Transcriptome analysis of flower colour reveals the correlation between SNP and differential expression genes in Phalaenopsis

Ding Yu,Wang Ma-Yin,Yang Ding-Hai,Hao Dai-Cheng,Li Wei-Shi,Ling Peng,Xie Shang-Qian 한국유전학회 2023 Genes & Genomics Vol.45 No.12

Background Phalaenopsis is an important ornamental plant that has great economic value in the world flower market as one of the most popular flower resources. Objective To investigate the flower colour formation of Phalaenopsis at the transcription level, the genes involved in flower color formation were identified from RNA-seq in this study. Methods In this study, white and purple petals of Phalaenopsis were collected and analyzed to obtained (1) differential expression genes (DEGs) between white and purple flower color and (2) the association between single nucleotide polymorphisms (SNP) mutations and DEGs at the transcriptome level. Results The results indicated that a total of 1,175 DEGs were identified, and 718 and 457 of them were up- and down-regulated genes, respectively. Gene Ontology and pathway enrichment showed that the biosynthesis of the secondary metabolites pathway was key to color formation, and the expression of 12 crucial genes (C4H, CCoAOMT, F3’H, UA3’5’GT, PAL, 4CL, CCR, CAD, CALDH, bglx, SGTase, and E1.11.17) that are involved in the regulation of flower color in Phalaenopsis. Conclusion This study reported the association between the SNP mutations and DEGs for color formation at RNA level, and provides a new insight to further investigate the gene expression and its relationship with genetic variants from RNA-seq data in other species.

Measure Correlation Analysis of Network Flow Based On Symmetric Uncertainty

( Shi Dong ),( Wei Ding ),( Liang Chen ) 한국인터넷정보학회 2012 KSII Transactions on Internet and Information Syst Vol.6 No.6

In order to improve the accuracy and universality of the flow metric correlation analysis, this paper firstly analyzes the characteristics of Internet flow metrics as random variables, points out the disadvantages of Pearson Correlation Coefficient which is used to measure the correlation between two flow metrics by current researches. Then a method based on Symmetrical Uncertainty is proposed to measure the correlation between two flow metrics, and is extended to measure the correlation among multi-variables. Meanwhile, the simulation and polynomial fitting method are used to reveal the threshold value between different correlation degrees for SU method. The statistical analysis results on the common flow metrics using several traces show that Symmetrical Uncertainty can not only represent the correct aspects of Pearson Correlation Coefficient, but also make up for its shortcomings, thus achieve the purpose of measuring flow metric correlation quantitatively and accurately. On the other hand, reveal the actual relationship among fourteen common flow metrics.

Determination of Energy Levels and Crystallographic Sites of Sm[sup 2+] Ions Doped in SrZn[sub 2](PO[sub 4])[sub 2]

Ding, Haiyan,Huang, Yanlin,Wei, Donglei,Shi, Liang,Qiao, Xuebin,Seo, Hyo Jin The Electrochemical Society 2009 Journal of the Electrochemical Society Vol.156 No.10

Effect of support on the performance of Mn–Cu oxides for low temperature selective catalytic reduction of NO with NH3

Wei-Guo Pan,Jie-nan Hong,Rui-Tang Guo,Wen-long Zhen,Hong-lei Ding,Qiang Jin,Cheng-gang Ding,Shi-yi Guo 한국공업화학회 2014 Journal of Industrial and Engineering Chemistry Vol.20 No.4

MnOx–CuOx/TiO2 and MnOx–CuOx/Al2O3 catalysts were prepared by sol–gel method and used for low temperature selective catalytic reduction of NO with NH3. The results showed that MnOx–CuOx/TiO2 had better catalytic activity and SO2 resistance than MnOx–CuOx/Al2O3 in the temperature range of 100–250 ℃. The properties of the catalysts were characterized by using XRD, N2 adsorption, temperature programmed reduction (H2-TPR) and temperature programmed desorption (NH3-TPD). It was found that the support has a great impact on the acidity of catalyst; TiO2 and Al2O3 can promote the formation of Lewis acid sites and Bro¨ nsted acid sites respectively.

Chinese Patients with Gastric Cancer Need Targeted Adjuvant Chemotherapy Schemes

Shi, Wen-Tao,Wei, Lei,Xiang, Jin,Su, Ke,Ding, Qiong,Tang, Meng-Jie,Li, Ji-Qiang,Guo, Yi,Wang, Pu,Zhang, Jing-Wei Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.10

Background: Gastric cancer (GC) is one of the most common cancers in China. Adjuvant chemotherapy (AC) is a routine auxiliary treatment for GC recommended by the guidelines issued in 2011 by the Ministry of Health of the People's Republic of China, but the relevant credible consequences in China have been insufficient because of China's late start and ethical concerns. Methods: A series of databases, including Cochrane Library, MEDLINE, EMBASE, the Chinese database of the National Knowledge Infrastructure and the VIP database, were searched by 2 reviewers independently for studies investigating AC for GC through March 2012. The retrieved literature was screened according to the eligibility criteria. Results: A total of 35 randomized control trials (RCTs) were subjected to the final analysis, including 4,043 patients in treatment group and 3,884 in the control group, as well as 4 clinical-control trials (CCTs), which accessed the final analysis with 238 and 252 patients, respectively. AC reduced the risk of death as a protective treatment with statistical significance (HR=0.91, 95%CI: [0.85, 0.97], P=0.002), and it seemed more effective for Asian than non-Asian patients. The effects of AC were not influenced by the starting time (P>0.05). D2 lymphadenectomy-based chemotherapy was effective (HR=0.89, 95%CI: [0.80, 0.99], P=0.04). Oral S-1 40 mg/m2 after D2 lymphadenectomy might be a better choice for Asians with advanced GC and might result in a greater reduction of adverse events than in non-Asian patients. GRADE quality assessment determined that the strength of the evidence from foreign studies from Europe, the United States and Asian countries other than China was high, while it was moderate for Chinese studies. Conclusion: AC was effective or even curative in Chinese patients in general, although it is still necessary to optimize a targeted AC scheme for Chinese patients with GC.

Benzo-thia-fused [ <i>n</i> ]thienoacenequinodimethanes with small to moderate diradical characters: the role of pro-aromaticity <i>versus</i> anti-aromaticity

Shi, Xueliang,Quintero, Estefaní,a,Lee, Sangsu,Jing, Linzhi,Herng, Tun Seng,Zheng, Bin,Huang, Kuo-Wei,Ló,pez Navarrete, Juan T.,Ding, Jun,Kim, Dongho,Casado, Juan,Chi, Chunyan Royal Society of Chemistry 2016 Chemical Science Vol.7 No.5

<▼1><P>Pro-aromatic <B>Th<I>n</I>-TIPS</B> exhibits distinctly different physical properties from anti-aromatic <B>S<I>n</I>-TIPS</B>.</P></▼1><▼2><P>Open-shell singlet diradicaloids have recently received much attention due to their unique optical, electronic and magnetic properties and promising applications in materials science. Among various diradicaloids, quinoidal π-conjugated molecules have become the prevailing design. However, the need for a fundamental understanding on how the fusion mode and pro-aromaticity/anti-aromaticity affect their diradical character and physical properties remains unaddressed. In this work, a series of pro-aromatic benzo-thia-fused [<I>n</I>]thienoacenequinodimethanes (<B>Th<I>n</I>-TIPS</B> (<I>n</I> = 1–3) and <B>BDTh-TIPS</B>) were synthesized and compared with the previously reported anti-aromatic bisindeno-[<I>n</I>]thienoacenes (<B>S<I>n</I>-TIPS</B>, <I>n</I> = 1–4). The ground-state geometric and electronic structures of these new quinoidal molecules were systematically investigated by X-ray crystallographic analysis, variable temperature NMR, ESR, SQUID, Raman, and electronic absorption spectroscopy, assisted by DFT calculations. It was found that the diradical character index (<I>y</I><SUB>0</SUB>) increased from nearly zero for <B>Th1-TIPS</B> to 2.4% for <B>Th2-TIPS</B>, 18.2% for <B>Th3-TIPS</B>, and 38.2% for <B>BDTh-TIPS</B>, due to the enhanced aromatic stabilization. Consequently, with the extension of molecular size, the one-photon absorption spectra are gradually red-shifted, the two-photon absorption (TPA) cross section values increase, and the singlet excited state lifetimes decrease. By comparison with the corresponding anti-aromatic analogues <B>S<I>n</I>-TIPS</B> (<I>n</I> = 1–3), the pro-aromatic <B>Th<I>n</I>-TIPS</B> (<I>n</I> = 1–3) exhibit larger diradical character, longer singlet excited state lifetime and larger TPA cross section value. At the same time, they display distinctively different electronic absorption spectra and improved electrochemical amphotericity. Spectroelectrochemical studies revealed a good linear relationship between the optical energy gaps and the molecular length in the neutral, radical cationic and dicationic forms. Our research work discloses a significant difference between the pro-aromatic and anti-aromatic quinoidal compounds and provides guidance for the design of new diradicaloids with desirable properties.</P></▼2>

Event-triggered Fusion Estimation for Nonlinear Stochastic System with Unknown Parameters and Transmission Fading Over Sensor Networks

Yeming Shi,Guoliang Wei,Derui Ding 제어·로봇·시스템학회 2022 International Journal of Control, Automation, and Vol.20 No.5

This paper investigates an event-triggered fusion estimation problem for a class of discrete-time nonlinear stochastic systems with unknown parameters and transmission fading over sensor networks (SNs). The system with unknown and bounded parameters is considered in this paper, which is more practical compared with traditional systems. The fading of local estimation information will occur during the remote transmission. Therefore, the objective of this paper is to design a new fusion method based on unknown parameters and faded local estimation information. With the help of Lyapunov-type analysis approaches and quadratic cost function, sufficient conditions are established to ensure the input-to-state stability (ISS) of the dynamics of estimation errors and obtain the bound of estimation errors in the mean square sense. Finally, an appropriate fusion estimation method is proposed to estimate both unknown parameters and system states. At last, an illustrative simulation is utilized to verify the feasibility of the proposed design scheme.

An optimization design study of producing transuranic nuclides in high flux reactor

Xu Wei,Li Jian,Zhao Jing,She Ding,Liu Zhihong,Xie Heng,Shi Lei 한국원자력학회 2023 Nuclear Engineering and Technology Vol.55 No.8

Transuranic nuclides (such as 238Pu, 252Cf, 249Bk, etc.) have a wide range of application in industry, medicine, agriculture, and other fields. However, due to the complex conversion chain and remarkable fission losses in the process of transuranic nuclides production, the generation amounts are extremely low. High flux reactor with high neutron flux and flexible irradiation channels, is regarded as the promising candidate for producing transuranic nuclides. It is of great significance to increase the conversion ratio of transuranic nuclides, resulting in higher efficiency and better economy. In this paper, we perform an optimization design evaluation of producing transuranic nuclides in high flux reactor, which includes optimization design of irradiation target and influence study of reactor core loading. It is demonstrated that the production rate increases with appropriately determined target material and target structure. The target loading scheme in the irradiation channel also has a significant influence on the production of transuranic nuclides

Selection of the Lowest Instrumented Vertebra and Relative Odds Ratio of Distal Adding-on for Lenke Type 1A and 2A Curves in Adolescent Idiopathic Scoliosis: A Systematic Review and Meta-analysis

Che-Wei Liu,Lawrence G. Lenke,Lee A. Tan,Taemin Oh,Kou-Hua Chao,Shi-Ding Lin,Ru-Yu Pan 대한척추신경외과학회 2020 Neurospine Vol.17 No.4

Objective: To examine existing literature and pool the data to determine the relative odds ratio of “adding-on” (AO) based on various reported criteria for lower instrumented vertebra (LIV) selection in Lenke type 1A and 2A curves. Methods: Using electronic databases, studies reporting on AO and LIV selection in Lenke type 1A and 2A curves were identified. Studies were excluded if they failed to meet the following criteria: ≥30 patients, Lenke type 1A or 2A curves, thoracic-only fusions, and inclusion of outcome differences in AO and non-AO groups. Review articles, letters, and case reports were excluded. Results: Six studies were identified reporting on 732 patients with either Lenke type 1A or 2A curves treated with thoracic-only fusions. Five different landmarks were used for LIV selection in these studies including the stable vertebra (SV) -1, end vertebra (EV) +1, neutral vertebra (NV), touched vertebra (TV), and substantially touched vertebra (STV) versus nonsubstantially touched vertebra (nSTV) +1. The pooled odds ratios of AO for choosing LIV at levels above the afore landmarks (i.e., ending the construct “short”) versus at the landmarks were 2.59 (SV-1), 2.43 (EV+1), 3.05 (NV), 3.40 (TV), and 4.52 (STV/nSTV+1), all at 95% confidence interval. Conclusion: Five landmarks shared a similar characteristic in that the incidence of AO was significantly higher if the LIV was proximal to the chosen landmark. In addition, choosing STV/(nSTV+1) as the LIV have the lowest absolute risk of AO and the greatest risk reduction. If additional levels were fused (i.e., LIV distal to the landmark), there was no statistically significant benefit in further reducing the risk of AO. Selection of the optimal LIV is a complex issue and spine surgeons must balance the risk of AO with the need for motion preservation in young patients.

Extraction of density-of-states in amorphous InGaZnO thin-film transistors from temperature stress studies

Xing-Wei Ding,Jianhua Zhang,Weimin Shi,Hao Zhang,Chuanxin Huang,Jun Li,Xueyin Jiang,Zhilin Zhang 한국물리학회 2014 Current Applied Physics Vol.14 No.12

The instability of amorphous InGaZnO (a-IGZO) thin-film transistors (TFTs) with different active layer thicknesses under temperature stress has been investigated through using the density-of-states (DOS). Interestingly, the a-IGZO TFT with 22 nm active layer thickness showed a better stability than the others, which was observed from the decrease of interfacial and semiconductor bulk trap densities. The DOS was calculated based on the experimentally-obtained activation energy (EA), which can explain the experimental observations. We developed the high-performance Al2O3 TFT with 22 nm IGZO channel layer (a high mobility of 7.4 cm2/V, a small threshold voltage of 2.8 V, a high Ion/Ioff 1.8 107, and a small SS of 0.16 V/dec), which can be used as driving devices in the next-generation flat panel displays.