Effect of Pitting Corrosion on the Stress Intensity Factor Magnitude and Distribution

Shan-Hua Xu,Haijiang Zhang,Biao Nie,Zhexun Zhang 한국강구조학회 2021 International Journal of Steel Structures Vol.21 No.4

The fracture and fatigue performance of corroded steel components show signifi cant degradation in both the crack initiation and propagation stage. This study is aimed to research the fracture behavior degradation mechanism of corroded steel members through investigating the eff ects of pits on stress intensity factor magnitude and distribution. The numerical simulation method was adopted, and a series of specimens with diff erent sizes and shapes of corrosion pits were modeled. It was found that the pitting-degradation models would show a more intense displacement and stress fi eld. A greater value of stress intensity factor SIF could be observed in model interior when the specimens were attacked by corrosion pits. The SIF distribution characteristic along thickness direction was aff ected by ratios of pit depth to radius. According to SIF numerical results, the premature fracture and shorter fatigue life induced by corrosion pits could be attributed to the higher SIF value compared with non-corrosion one.

Diabetes Mellitus Reduces Prostate Cancer Risk - No Function of Age at Diagnosis or Duration of Disease

Xu, Hua,Mao, Shan-Hua,Ding, Guan-Xiong,Ding, Qiang,Jiang, Hao-Wen Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.1

Background: Prior studies examining the relation between diabetes mellitus (DM) and prostate cancer risk have reported controversial findings. We examined this association by conducting a detailed meta-analysis of the peer-reviewed literature. Methods: A comprehensive search for articles of MEDLINE and EMBASE databases and bibliographies of retrieved articles published up to November, 2012 was performed. Methodological quality assessment of the trials was based on the Newcastle-Ottawa Scaleq and the meta-analysis was performed using STATA 12.0. Dose-response regression was conducted with SPSS 19.0. Results: We included 29 studies in the meta-analysis (13 case-control studies, 16 cohort studies), and found an inverse association between DM and prostate cancer (relative risk (RR) 0.84, 95% confidence interval (CI), 0.78-0.91). An inverse association was also observed in non-Asian populations (RR 0.81, 95% CI 0.76-0.87) and population-based studies (RR 0.80, 95% CI 0.77-0.91). No statistical significance was found of the association between prostate cancer risk and the duration of DM (p=0.338), and risk seemed not related with the age of DM diagnosis. Conclusions: This study suggested an inverse relationship between DM and prostate cancer, but without links to duration of disease or age of diagnosis.

A Wireless Sensor Network Clustering Algorithm based on Hypergraph

Xu Qian,Hu Ji-cheng,Lin Hai,Kong Ruo-shan,Luo Yong-en,Zhu Li,Mao Hua-qing 보안공학연구지원센터 2016 International Journal of Future Generation Communi Vol.9 No.6

The paper proposes a clustering algorithm for wireless sensor network based on hypergraph. Under the hypergraph model, a wireless sensor network is mapped to a hypergraph. Then a hierarchical iterative clustering algorithm is applied to the hypergraph, thus dividing the hypergraph into multiple parts. A cluster head is selected from each part. In order to improve the partitioning process, a new modularity function is proposed. Compared with the classic clustering algorithm LEACH, simulation shows that our algorithm performs better in energy consuming and network lifetime.

CULTIVATION OF STUDENTS’ CORE LITERACY BASED ON THE MATHEMATICAL CULTURE PERSPECTIVE

Hua Nan,Shan Tong,Yu Xu 영남수학회 2019 East Asian mathematical journal Vol.35 No.2

In recent years, the term core literacy has been popular in educational circles all over the world, and there are more and more research on core literacy . At the same time, the mathematical culture has also been highly valued on a global scale. The mathematical culture is a part of college students’ cultural quality, and then, what is the connection between the mathematical culture and mathematical core literacy? How to improve the mathematical core literacy of contemporary college students? This paper gives the corresponding answers to these two questions. By illustrating the concrete implementation of the course ′′Mathematical Culture′′ offered by Yanbian University, this paper discusses various mea- sures for cultivating students’ core qualities in Chinese universities. It must be useful and promote the research on mathematical core literacy for the educators in various countries.

On the Feasibility of Interference Alignment in the Cellular Network

( Hua Chen ),( Shan Wu ),( Ping Hu ),( Zhudi Xu ) 한국인터넷정보학회 2017 KSII Transactions on Internet and Information Syst Vol.11 No.11

In this paper, we investigate the feasibility of interference alignment(IA) in signal space in the scenario of multiple cell and multiple user cellular networks, as the feasibility issue is closely related to the solvability of a multivariate polynomial system, we give the mathematical analysis to support the constraint condition obtained from the polynomial equations with the tools of algebraic geometry, and a new distribute IA algorithm is also provided to verify the accessibility of the constraint condition for symmetric system in this paper. Simulation results illustrate that the accessibility of the constraint condition is hold if and only if the degree of freedom(DoF) of each user can be divided by both the transmit and receive antenna numbers.

CULTIVATION OF STUDENTS' CORE LITERACY BASED ON THE MATHEMATICAL CULTURE PERSPECTIVE

Nan, Hua,Tong, Shan,Xu, Yu The Youngnam Mathematical Society 2019 East Asian mathematical journal Vol.35 No.2

In recent years, the term core literacy has been popular in educational circles all over the world, and there are more and more research on core literacy. At the same time, the mathematical culture has also been highly valued on a global scale. The mathematical culture is a part of college students' cultural quality, and then, what is the connection between the mathematical culture and mathematical core literacy? How to improve the mathematical core literacy of contemporary college students? This paper gives the corresponding answers to these two questions. By illustrating the concrete implementation of the course "Mathematical Culture" offered by Yanbian University, this paper discusses various measures for cultivating students' core qualities in Chinese universities. It must be useful and promote the research on mathematical core literacy for the educators in various countries.

Experimental and Theoretical Investigation on Flexural Behavior of Corroded Steel Beams Strengthened by CFRP Plate

Zong-Xing Zhang,Shan-Hua Xu,Lin Mu,Sheng-Yuan Peng 대한토목학회 2020 KSCE JOURNAL OF CIVIL ENGINEERING Vol.24 No.7

To investigate the flexural behavior of corroded steel beams strengthened by carbon fiber reinforced polymer (CFRP) plate, flexural test of five steel beams were carried out. The effects of corrosion and prestressing force levels on the flexural capacity, failure modes and interfacial stress were investigated. Meanwhile, considering the corrosion surface the calculation method of flexural capacity of corroded beams strengthened by CFRP plate was also established. The results showed that failure modes of corroded beams were the fracture of the CFRP plate after the shear failure of interface on the mid-span and fracture location of CFRP plate was mostly at the loading point. The rough surface of the corroded steel can enhance the efficiency of stress transfer at the interface, thereby improving the effective bond length of the interface. The shear stress was mainly concentrated on the CFRP plate end, and peak value appeared at the loading point. Compared the reference beam, the ultimate flexural capacity of the corroded beam strengthened by CFRP plate with 15% prestress level increased at a ratio of 21%, and utilization ratio of the CFRP plates was up to 71.59%.

FOXA1: a Promising Prognostic Marker in Breast Cancer

Hu, Qing,Luo, Zhou,Xu, Tao,Zhang, Jun-Ying,Zhu, Ying,Chen, Wei-Xian,Zhong, Shan-Liang,Zhao, Jian-Hua,Tang, Jin-Hai Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.1

Accurate diagnosis and proper monitoring of cancer patients remain important obstacles for successful cancer treatment. The search for cancer biomarkers can aid in more accurate prediction of clinical outcome and may also reveal novel predictive factors and therapeutic targets. One such prognostic marker seems to be FOXA1. Many studies have shown that FOXA1 is strongly expressed in a vast majority of cancers, including breast cancer, in which high expression is associated with a good prognosis. In this review, we summarize the role of this transcription factor in the development and prognosis of breast cancer in the hope of providing insights into utility of FOXA1 as a novel biomarker.

Clinical and Pathologic Features of Multifocal and Multicentric Breast Cancer in Chinese Women: A Retrospective Cohort Study

Mei-rong Zhou,Zhong-hua Tang,Jing Li,Jin-Hu Fan,Yi Pang,Hong-jian Yang,Shan Zheng,Jing-qiao Bai,Ning Lv,You-Lin Qiao,Feng Xu,Hai-zhi Qi 한국유방암학회 2013 Journal of breast cancer Vol.16 No.1

Purpose: This study aims to analyze the clinical-pathological characteristics of multifocal and multicentric breast cancer (MMBC) in Chinese women. Methods: Sixty-seven cases with MMBC were randomly collected and reviewed at seven hospitals in representative districts of China during 1999 to 2008. Results: The incidence of MMBC in breast cancer in China was 1.75%. Compared to those with unifocal breast cancer, women with MMBC were more likely to have larger tumor size, lymph node metastasis (59.70% vs. 45.62%) and stage III to IV (46.26% vs. 21.10%). The peak age at onset of MMBC was 40 to 49 years old and has been gradually increasing during 1999 to 2008. Most of the MMBC women were treated with surgery and adjuvant therapy. Conclusion: In China, the incidence of MMBC in breast cancer is significantly lower than that in Western countries. Compared to unifocal breast cancer, MMBC is biologically more aggressive. Most MMBC women underwent mastectomy, instead of breast conservation surgery.

Inhibitory effects of piceatannol on human cytomegalovirus (hCMV) in vitro

Wang San-Ying,Zhang Jing,Xu Xiao-Gang,Su Hui-Li,Xing Wen-Min,Zhang Zhong-Shan,Jin Wei-Hua,Dai Ji-Huan,Wang Ya-Zhen,He Xin-Yue,Sun Chuan,Yan Jing,Mao Gen-Xiang 한국미생물학회 2020 The journal of microbiology Vol.58 No.8

Human cytomegalovirus (hCMV) is a ubiquitous herpesvirus, which results in the establishment of a latent infection that persists throughout the life of the host and can be reactivated when the immunity is low. Currently, there is no vaccine for hCMV infection, and the licensed antiviral drugs mainly target the viral enzymes and have obvious adverse reactions. Thus, it is important to search for compounds with antihCMV properties. The present study aimed to investigate the suppressive effects of piceatannol on hCMV Towne strain infection and the putative underlying mechanisms using human diploid fibroblast WI-38 cells. Piceatannol supplementation prevented the lytic changes induced by hCMV infection in WI-38 cells. Furthermore, piceatannol suppressed the expression of hCMV immediate-early (IE) and early (E) proteins as well as the replication of hCMV DNA in a dose-dependent manner. Moreover, hCMV-induced cellular senescence was suppressed by piceatannol, as shown by a decline in the senescence-associated β-galactosidase (SA-β-Gal) activity and decreased production of intracellular reactive oxygen species (ROS). p16INK4a, a major senescence-associated molecule, was dramatically elevated by current hCMV infection that was attenuated by pre-incubation with piceatannol in a dose-dependent manner. These results demonstrated that piceatannol suppressed the hCMV infection via inhibition of the activation of p16INK4a and cellular senescence induced by hCMV. Together, these findings indicate piceatannol as a novel and potent anti-hCMV agent with the potential to be developed as an effective treatment for chronic hCMV infection.