Computed tomographic assessment of the lacrimal sac fossa in southwest population of Iran

Samad Shahryari,Mohammad Ghasem Hanafi,Rouhangiz Kamankesh,Atefeh Mahdianrad,Ali Reza Eftekhari Moghadam 대한해부학회 2022 Anatomy & Cell Biology Vol.55 No.3

To determine the morphology of the lacrimal sac fossa and bony nasolacrimal duct using computed tomography for obtaining detailed anatomical understanding of the drainage system and utilizing these measurements in planning for dacryocystorhinostomy (DCR) and nasolacrimal duct (NLD) obstruction in normal southwest (SW) population of Iran. One-hundred-sixty-five cases referred for the diagnosis of neuro-ophthalmic conditions were retrospectively studied. Measurements of lacrimal sac fossa were taken on three anatomical sections (upper, middle, and lower planes) utilizing a digital caliper/protractor instrument. Lacrimal thickness and two measurements of maxillary bone thickness were taken at each plane—namely, the “midpoint thickness” and the “maximum thickness.” The anterior extent of the nasal mucosa and NLD width was also evaluated. The mean maximum thickness of the maxillary bone at the three anatomical planes of the lacrimal sac fossa was 4.07 mm, 4.78 mm, and 5.60 mm, respectively. The midpoint thickness of the maxillary bone at each plane was 2.38 mm, 1.99 mm, and 1.68 mm, respectively, in both sexs. The lacrimal bone thickness at each level was 0.76 mm, 0.69 mm, and 0.67 mm, respectively. The proportion of the lacrimal sac fossa comprising the lacrimal bone at lower plane was 43.57% and showed a positive correlation with age (P=0.01). The mean anteroposterior bony nasolacrimal diameter was 5.94 mm with no significant difference between patient sex and age. According to the results, its indicate that performing an osteotomy during DCR could be easier in the Iranian SW population compared to other ethnics.

Generation and Expression in Plants of a Single-Chain Variable Fragment Antibody Against the Immunodominant Membrane Protein of Candidatus Phytoplasma Aurantifolia

( F Shahryari ),( M R Safarnejad ),( M Shams Bakhsh ),( S Schillberg ),( G Nolke ) 한국미생물 · 생명공학회 2013 Journal of microbiology and biotechnology Vol.23 No.8

Witches`` broom of lime is a disease caused by Candidatus Phytoplasma aurantifolia, which represents the most significant global threat to the production of lime trees (Citrus aurantifolia). Conventional disease management strategies have shown little success, and new approaches based on genetic engineering need to be considered. The expression of recombinant antibodies and fragments thereof in plant cells is a powerful approach that can be used to suppress plant pathogens. We have developed a single-chain variable fragment antibody (scFvIMP6) against the immunodominant membrane protein (IMP) of witches`` broom phytoplasma and expressed it in different plant cell compartments. We isolated scFvIMP6 from a naive scFv phage display library and expressed it in bacteria to demonstrate its binding activity against both recombinant IMP and intact phytoplasma cells. The expression of scFvIMP6 in plants was evaluated by transferring the scFvIMP6 cDNA to plant expression vectors featuring constitutive or phloem specific promoters in cassettes with or without secretion signals, therefore causing the protein to accumulate either in the cytosol or apoplast. All constructs were transiently expressed in Nicotiana benthamiana by agroinfiltration, and antibodies of the anticipated size were detected by immunoblotting. Plant-derived scFvIMP6 was purified by affinity chromatography, and specific binding to recombinant IMP was demonstrated by enzyme-linked immunosorbent assay. Our results indicate that scFvIMP6 binds with high activity and can be used for the detection of Ca. Phytoplasma aurantifolia and is also a suitable candidate for stable expression in lime trees to suppress witches`` broom of lime.

Minimum cost design of RCMRFs based on consistent approximation method

Alireza Habibi,Mobin Shahryari,Hasan Rostami 사단법인 한국계산역학회 2020 Computers and Concrete, An International Journal Vol.26 No.1

In this paper, a procedure for automated optimized design of reinforced concrete frames has been presented. The procedure consists of formulation and solution of the design problem in the form of an optimization problem. The minimization of total cost of R/C frame has been taken as the objective of optimization problem. In this research, consistent approximation method is applied to explicitly formulate constraints and objective function in terms of the design variables. In the presented method, the primary optimization problem is replaced with a sequence of explicit sub-problems. Each sub-problem is efficiently solved using the Sequential Quadratic Programming (SQP) method. The proposed method is demonstrated through a four-story frame and an eight-story frame, and the optimum results are compared with those in the available literature. It is shown that the proposed method can be easily applied to obtain rational, reliable, economical and practical designs for Reinforced Concrete Moment Resisting Frames (RCMRFs) while it is converged after a few analyses.

Optimization of a radiator for a MPFL system in a GEO satellite

Afshari, Behzad Mohasel,Abedi, Mohsen,Shahryari, Mehran Techno-Press 2017 Advances in aircraft and spacecraft science Vol.4 No.6

One of the components that used in the satellite thermal control subsystem is the Mechanically Pumped Fluid Loop (MPFL) system; this system mostly used in geosynchronous orbit (GEO) satellites, and can transfer heat from a hot point to a cold point using the fluid which circulated in a closed loop. Heat radiates to the deep space at the cold plate to cool down the fluid temperature. In this research, the radiative heatexchanger (RHX) for a MPFL system is optimized. The genetic algorithm has been used for minimizing the total mass and pressure drop by considering a constant transferred heat rate at the heat exchanger. The optimization has been done in two cases. In case I, two parameters are considered as a goal function, so optimization is performed using NSGA-II method. Results of optimization are shown in the pareto diagram. In case II, the diameter of pipe is considered constant, so the optimized value for distances of the parallel pipes is obtained by using the genetic algorithm, in which the system has the least total mass. Results show that in the RHX, by increasing the pipe diameter, pressure drop decreases and total mass increases. Also by considering a constant value for pipe diameter, an optimum distance between pipes and pipe length are obtained in which the system has a minimum mass.

Characteristics and electrical conductivity of graphene and graphene oxide for adsorption of cationic dyes from liquids: Kinetic and thermodynamic study

Omid Moradi,Vinod Kumar Gupta,Shilpi Agarwal,Inderjeet Tyagi,Mohammad Asif,Abdel Salam Hamdy Makhlouf,Hamidreza Sadegh,Ramin Shahryari-ghoshekandi 한국공업화학회 2015 Journal of Industrial and Engineering Chemistry Vol.28 No.-

Graphene (G) and Graphene oxide (GO) were employed in the present study for the removal of two toxiccationic dye Basic Red 12 (BR 12) and Basic Red 46 (BR 46), from aqueous solutions. Graphene oxide wassynthesized by Hummer–Offeman method, and then characterized by XRD (X-ray diffraction), and FT-IR(Fourier Transform Infrared spectroscopy). The influence of various physico-chemical parameters suchas electrical conductivity behaviors, contact time, solution pH, dye concentration and temperature werewell investigated and elucidated. The kinetics and thermodynamics of the toxic dye removal processwere also investigated; results clearly depicts that the kinetics of the removal of BR 12 and BR 46 using Gand GO as adsorbents follows a pseudo-second-order model. G and GO exhibited high-adsorptioncapacity for BR 12 and BR 46. The dye removal depends on the initial pH of the solution with themaximum uptake occurring at about pH 9. Moreover, the thermodynamic results confirmed thatadsorption of dye BR 46 on G and GO were exothermic and adsorption of dye BR 12 on G and GO wereendothermic in nature. The electrical conductivity behaviors of the aqueous solution were found to beenhanced by oxidation of graphene.

Adsorption of malachite green from aqueous solution by carboxylate group functionalized multi-walled carbon nanotubes: Determination of equilibrium and kinetics parameters

M. Rajabi,B. Mirza,K. Mahanpoor,M. Mirjalili,F. Najafi,O. Moradi,H. Sadegh,R. Shahryari-ghoshekandi,M. Asif,I. Tyagi,S. Agarwal,Vinod Kumar Gupta 한국공업화학회 2016 Journal of Industrial and Engineering Chemistry Vol.34 No.-

MWCNTs functionalized with the carboxylate group are used as efficient adsorbent for the rapid removaland fast adsorption of malachite green from the aqueous solutions. The optimized contact time and pHwere 10 min and 9, respectively. The effect of temperature revealed that the adsorption capacity ofmalachite green (MG) dye increased with increasing contact time, temperature and pH of the workingsolution. The adsorption equilibrium and kinetic data was well fitted and found to be in good agreementwith the Langmuir isotherm model and pseudo second order kinetic model respectively with highcorrelation coefficient.

Cytochrome P450 1B1 polymorphisms and risk of renal cell carcinoma in men.

Chang, Inik,Fukuhara, Shinichiro,Wong, Darryn K,Gill, Ankurpreet,Mitsui, Yozo,Majid, Shahana,Saini, Sharanjot,Yamamura, Soichiro,Chiyomaru, Takeshi,Hirata, Hiroshi,Ueno, Koji,Arora, Sumit,Shahryari, V Saikon Pub. Co 2014 TUMOR BIOLOGY Vol.35 No.10

<P>The cytochrome P450 1B1 (CYP1B1) enzyme activates xenobiotics to reactive forms as well as convert estradiol to 4-hydroxy-estradiol that has been shown to play a role in the carcinogenesis process of the kidney in male but not female animals. Prior reports show polymorphic variants of CYP1B1 to alter catalytic activity, and thus, we hypothesize that polymorphisms of the CYP1B1 gene are involved in the malignant transformation of the renal cell in men. The genetic distributions of five CYP1B1 polymorphisms were analyzed by polymerase chain reaction-restriction fragment length polymorphism in 480 normal healthy subjects and 403 sporadic renal cell carcinoma cases. All subjects were Caucasian men. The sites evaluated were codons 48 (C??G, Arg??Gly, rs10012), 119 (G??T, Ala??Ser, rs1056827), 432 (C??G, Leu??Val, rs1056836), 449 (C??T, Asp, rs1056837), and 453 (A??G, Asn??Ser, rs1800440). A trend was demonstrated for the 432 Val/Val (χ2, P?=?0.06) and 449 T/T (χ2, P?=?0.1) genotypes to play a protective role against renal cancer. Odds ratio (95 % confidence interval) for Val/Val compared to Leu/Leu at codon 432 was 0.65 (0.44-0.95) and T/T compared to C/C at codon 449 was 0.67 (0.45-0.99). Codons 432 and 449 were observed to be linked (D?=?0.24), and haplotype involving 432 Val and 449 T was significantly reduced in cancer cases (P?=?0.04). No association was found, however, when analyzing polymorphic sites with clinical stage of cancer. These results demonstrate polymorphisms of CYP1B1 to be associated with renal carcinogenesis and are of importance in understanding their role in the pathogenesis of renal cell carcinoma.</P>