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양옥승 ( Ok Seung Yang ) 한국유아교육학회 2013 유아교육연구 Vol.33 No.6
본 연구의 목적은 필자가 개발한「VPE 프로그램」`Verbal Plan and Evaluation program: 언어적 계획·평가 프로그램`이 만 3-5세 유아의 자기조절력에 미치는 효과를 검증하는데 있다. 이를 위해 이 연구에서는 통제집단에 처치를 가하지 않은 사전·사후 검사 설계`untreated control group design with pretest and posttest` 방법을 적용하였다. 연구대상은 서울지역에 위치한 어린이집 유아 만 3세 37명, 만 4세 37명, 만 5세 39명 등 총 113명이었고, 효과를 측정하기 위한 도구로는 필자의 ``영유아 자기조절력 측정도구``가 사용되었다. 본 연구의 결과를 요약하면 다음과 같다. 첫째, 「VPE 프로그램」은 만 3-5세 유아의 자기조절력을 향상시킨다. 둘째, 「VPE 프로그램」이 유아의 자기조절력에 미치는 영향은 연령별로 차이가 있다. 셋째, 개인 내적 요인`연령, 성별, 지능`을 통제했을 때에도 「VPE 프로그램」은 유아의 자기조절력 향상에 효과적이다. 이러한 사실들은 만 3세-5세 유아의 자기조절력을 증진시키기 위해서는 유아교육기관에서 자유선택활동 시간에 「VPE 프로그램」을 적용하는 것이 필요함을 시사한다. Recent neuroscience research in the brain development of children stresses that early childhood years are optimal for nurturing a healthy propensity for self-regulation. Building upon this neuroscience finding, this study investigates the efficacy of the Verbal Plan and Evaluation `VPE` program which guides young children in verbally planning, implementing, and verbally evaluating their choice of activities during free play time in terms of its effect on self-regulation development. Using the Untreated Control Group Design with Pre-and Post-test, subjects, totaling 113 children `37 children at age three, 37 children at age four and 39 children at age five` all enrolled in a child care center in Seoul, were given pre-and post-tests of Yang`s SREC `Self-Regulation in Early Childhood` Scale to measure their self-regulation. The findings of the study are as follows: First, the VPE program for 3-5 year-old improved their self-regulation ability. Second, the VPE program`s effects on the children`s self-regulation were different among the three age groups, indicating the influence of age on developmental capacity. Third, the VPE program improved the self-regulation of all of the 3-year-old, 4-year-old and 5-year-old children even when internal variables including age, gender and intelligence were taken into account. In other words, the VPE program is an effective program for developing self-regulation in 3-year-old, 4-year-old and 5-year-old children. Moreover, the components of the VPE program can be used in a variety of early childhood settings to encourage the plasticity of healthy self-regulation growth.
HPLC-based metabolic profiling and quality control of leaves of different Panax species
Seung-Ok Yang,Sang Won Lee,Young Ock Kim,Sang-Hyun Sohn,Young Chang Kim,Dong Yoon Hyun,Yoon Pyo Hong,Yu Su Shin 고려인삼학회 2013 Journal of Ginseng Research Vol.37 No.2
Leaves from Panax ginseng Meyer (Korean origin and Chinese origin of Korean ginseng) and P. quinquefolius (American ginseng) were harvested in Haenam province, Korea, and were analyzed to investigate patterns in major metabolites using HPLC-based metabolic profiling. Partial least squares discriminant analysis (PLS-DA) was used to analyze the the HPLC chromatogram data. There was a clear separation between Panax species and/or origins from different countries in the PLS-DA score plots. The ginsenoside compounds of Rg1, Re, Rg2, Rb2, Rb3, and Rd in Korean leaves were higher than in Chinese and American ginseng leaves, and the Rb1 level in P. quinquefolius leaves was higher than in P. ginseng (Korean origin or Chinese origin). HPLC chromatogram data coupled with multivariate statistical analysis can be used to profile the metabolite content and undertake quality control of Panax products.
YANG, Seung-Ok,KIM, So-Hyun,KIM, Yujin,KIM, Hee-Su,CHUN, Young-Jin,CHOI, Hyung-Kyoon Japan Society for Bioscience, Biotechnology, and A 2009 Bioscience, Biotechnology, and Biochemistry Vol.73 No.9
<P>Creating a plant-cell suspension culture involves first transferring the callus into liquid media, but there are no objective criteria for selecting the location of the callus to be transferred. In this study, inner and outer cells of <I>Catharanthus roseus</I> with various elicitors in solid-state cultures were differentiated by <SUP>1</SUP>H NMR (nuclear magnetic resonance) spectrometry and principal component analysis (PCA). It was found that the samples of various elicitors and relative locations could be separated in PCA-derived score plots. Especially, there was a clear separation between nontreated samples and those cotreated with silver nitrate and methyl jasmonate. Loading-plot analysis was therefore applied to data obtained from nontreated samples and those cotreated with silver nitrate and methyl jasmonate to determine the separation of major metabolites on score plots. The levels of valine, lactic acid, threonine, alanine, arginine, acetic acid, malic acid, succinic acid, citric acid, asparagine, choline, lactose, fumaric acid, phenylalanine, tryptophan, and formic acid were higher in the inner callus than in the outer callus, whereas 2-oxoglutaric acid, oxalacetic acid, sucrose, and glucose dominated in the outer callus. The results obtained in this study suggest that inner and outer calli can be differentiated by <SUP>1</SUP>H-NMR-based metabolomic analysis.</P>
YANG, Seung-Ok,KIM, So-Hyun,CHO, Sayeon,LEE, JaeHwan,KIM, Young-Suk,YUN, Sung-Seob,CHOI, Hyung-Kyoon Japan Society for Bioscience, Biotechnology, and A 2009 Bioscience, Biotechnology, and Biochemistry Vol.73 No.5
<P>Changes in metabolites in fermented soymilk prepared with selected <I>Bifidobacterium</I> and <I>Streptococci</I> strains were analyzed using a <SUP>1</SUP>H-NMR-based metabolomic technique. Principal components analysis (PCA) allowed the clear separation of 50% methanol extracts from fermented soymilk with different fermentation times by combining principal components PC1 and PC3, which accounted for 55.1% of the total variance. Loading plot analysis was performed to select major compounds contributing to the separation, and the relative levels of selected metabolites were determined. In addition, the free-radical scavenging activities of each sample were investigated, and the underlying mechanisms were elucidated by determining the total phenolics and total flavonoids contents of each sample. The present study suggests the usefulness of combining <SUP>1</SUP>H-NMR with PCA in discriminating fermented soymilk samples with different fermentation times, and elucidates of the factors affecting free-radical scavenging activities of fermented soymilk.</P>
( Seung Tae Han ),( Shin Han Song ),( Min Keun Kim ),( Jae Seok Kim ),( Byoung Geun Han ),( Seung Ok Choi ),( Jae Won Yang ) 대한신장학회 2011 Kidney Research and Clinical Practice Vol.30 No.3
The superior vena cava (SVC) syndrome refers to all clinical phenomena appeared as bronchial pneumonia, lymphoma, mediastinitis, and aortic aneurysm compress the superior vena cava and the veins in the vicinity in the superior mediastinum. Iatrogenic superior vena cava syndrome due to vascular stenosis or aneurysmal change has occurred by the repeated placement of cardiac pacemaker. Cardiac tamponade and hematoma have been reported in patients with end-stage renal disease due to impairment of blood coagulation caused by uremia. But acutely developed SVC syndrome was not reported after catheterization. In this report, we describe a case of acute SVC syndrome and mediastinal hematoma after insertion of internal jugular catheter for hemodialysis.