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      • KCI등재

        A review on phyto pharmacological, botanical and marketed formulation studies of Anethum sowa

        Sangeeta Singh,Mohammad Khalid,Muhammad Arif,Farogh Ahsan 경희대학교 융합한의과학연구소 2020 Oriental Pharmacy and Experimental Medicine Vol.20 No.4

        Anethum as vast growing aromatic plant of family umbelliferae which is extensively used in therapeutic preparations and in different cuisines. The plant is a local inhabitant of southern Europe known as Dill originating from Norse Dilla which means to have soothing and healing ability. The phytochemical investigation revealed the presence of flavonoids, glucosides, alkaloids, vitamins, minerals, proteins and essential oil. The present review emphasizes mainly on the significant information about its phytochemical investigations, pharmacological activities as well as ethnopharmacological properties as traditional medicine. The plant has been investigated and it displayed notable pharmacological activities such as antidiabetic, antimicrobial activity, antioxidant and cytotoxic activity, hypoglycemic and hematopoietic potential, insecticidal activity. The entire plant is important for the medicinal purpose which can be further explored and studied for future pharmaceutical perspective.

      • KCI등재

        Strained Si on Insulator as Potential Material for Forced Stacked Multi-threshold FinFET Based Inverter Considering Ultra Low-Power Applications

        Sangeeta Singh,Shashank Dubey,Saurabh Kharwar,P. N. Kondekar 한국전기전자재료학회 2019 Transactions on Electrical and Electronic Material Vol.20 No.4

        This work investigates the performance of strained Si on insulator as potential material for forced stacked multi-threshold FinFET based inverter considering its ultra low-power applications. Using the calibrated exhaustive 3D-TCAD mixed-mode simulation a comparative analysis of conventional and forced stack FinFET based inverters has been performed. The static and dynamic characteristics have been compared with conventional and forced stacked FinFET based inverter. The leakage in standby mode can be reduced through well-defi ned stack and multi-threshold (V TH ) transistors. Channel doping is optimized to get higher V TH devices. To improve the speed of circuits FinFETs are designed on strained Silicon on Insulator (sSOI) wafer. Uniform uniaxial tensile stress in sSOI gives the advantage of high ON current in n-FinFETs. It is observed that using strained FinFETs the maximum delay is reduced below 10 ps and using multi V TH forced stack technique the leakage power is reduced. Hence, forced stack technique based FinFET can evolve as a potential candidate for the future ultra-low power device applications.

      • KCI등재

        Role of copper pyrovanadate as heterogeneous photo-Fenton like catalyst for the degradation of neutral red and azure-B: An eco-friendly approach

        Sangeeta Kalal,Pinki Bala Punjabi,Narendra Pal Singh Chauhan,Noopur Ameta,Rakshit Ameta,Sudhish Kumar 한국화학공학회 2014 Korean Journal of Chemical Engineering Vol.31 No.12

        The heterogeneous photo-Fenton like process is a green chemical pathway. It has an edge over conven-tional Fenton and photo-Fenton processes as it does not require the removal of ferrous/ferric ions in the form of sludge. We prepeared copper pyrovanadate or Volborthite (Cu3V2(OH)2O7·2H2O) composite photocatalyst by wet chemicalmethod. The photocatalyst was characterized by SEM, XRD, IR, TGA/DSC, EDX and BET. Experiments demon-strated that catalyst could effectively catalyze degradation of neutral red and azure-B in presence of H2O2 in visiblelight. Moreover, the photo-Fenton-like catalytic activity of Cu3V2(OH)2O7·2H2O was much higher than CuO and V2O5,when used alone as photocatalyst. The effect of variation of different parameters, i.e., pH, amount of photocatalyst,concentration of dye, amount of H2O2 and light intensity was also investigated. The degradation was well fitted underpseudo-first-order reaction with a rate constant of 2.081×10−4sec−1and 3.876×10−4sec−1for neutral red and azure-B,respectively. Quality parameters of dye solutions before and after photo-Fenton degradation were also determined. Atentative mechanism involving•OH radical as an oxidant has been proposed. The high catalytic activity may be dueto the Cu3V2(OH)2O7·2H2O shell, which not only increased the surface hydroxyl groups, but also enhanced the interfacialelectron transfer. The catalyst has been found to possess good recyclability.

      • KCI등재

        Determination of Johnson–Cook Material Parameters for Armour Plate Using DIC and FEM

        Sangeeta Khare,Krishna Kumar,Shashank Choudhary,Pundan Kumar Singh,Rahul Kumar Verma,Puneet Mahajan 대한금속·재료학회 2021 METALS AND MATERIALS International Vol.27 No.12

        Understanding of material behavior of armour steel under large deformations and high strains during loading is very crucial indesigning steel structures for various applications. Johnson–Cook flow stress and Johnson–Cook failure models were adoptedfor modeling and predicting the material flow behavior of armour plate. The material parameters of Johnson–Cook flowstress have been determined experimentally from tests performed at different strain rates (10−4–1550 s−1) and temperatures(25–600 °C). The damage parameters of Johnson–Cook failure model were determined through experiments on flat tensilespecimens in combination with finite element simulation. Using these materials parameters, finite element simulations wereperformed on notch specimens of different radii between 2 mm and 20 mm loaded under tension. Load-strain curves werein good agreement with the experimentally obtained data. Triaxiality obtained from simulation were matched against thereported values from the literature.

      • SCOPUSKCI등재

        A Novel Approach for Deriving Test Scenarios and Test Cases from Events

        Singh, Sandeep K.,Sabharwal, Sangeeta,Gupta, J.P. Korea Information Processing Society 2012 Journal of information processing systems Vol.8 No.2

        Safety critical systems, real time systems, and event-based systems have a complex set of events and their own interdependency, which makes them difficult to test ma Safety critic Safety critical systems, real time systems, and event-based systems have a complex set of events and their own interdependency, which makes them difficult to test manually. In order to cut down on costs, save time, and increase reliability, the model based testing approach is the best solution. Such an approach does not require applications or codes prior to generating test cases, so it leads to the early detection of faults, which helps in reducing the development time. Several model-based testing approaches have used different UML models but very few works have been reported to show the generation of test cases that use events. Test cases that use events are an apt choice for these types of systems. However, these works have considered events that happen at a user interface level in a system while other events that happen in a system are not considered. Such works have limited applications in testing the GUI of a system. In this paper, a novel model-based testing approach is presented using business events, state events, and control events that have been captured directly from requirement specifications. The proposed approach documents events in event templates and then builds an event-flow model and a fault model for a system. Test coverage criterion and an algorithm are designed using these models to generate event sequence based test scenarios and test cases. Unlike other event based approaches, our approach is able to detect the proposed faults in a system. A prototype tool is developed to automate and evaluate the applicability of the entire process. Results have shown that the proposed approach and supportive tool is able to successfully derive test scenarios and test cases from the requirement specifications of safety critical systems, real time systems, and event based systems.

      • KCI등재

        Evaluation of β-1,4-Endoglucanases Produced by Bacilli Isolated from Paper and Pulp Mill Effluents Irrigated Soil

        ( Sangeeta Pandey ),( Rameshwar Tiwari ),( Surender Singh ),( Lata Nain ),( Anil Kumar Saxena ) 한국미생물 · 생명공학회 2014 Journal of microbiology and biotechnology Vol.24 No.8

        A total of 10 cellulase-producing bacteria were isolated from soil samples irrigated with paper and pulp mill effluents. The sequencing of 16S rRNA gene revealed that all isolates belonged to different species of genus Bacillus. Among the different isolates, B. subtilis IARI-SP-1 exhibited a high degree of β-1,4-endoglucanase (2.5 IU/ml), β-1,4-exoglucanase (0.8 IU/ml), and β-glucosidase (0.084 IU/ml) activity, followed by B. amyloliquefaciens IARI-SP-2. CMC was found to be the best carbon source for production of endo/exoglucanase and β-glucosidase. The β-1,4-endoglucanase gene was amplified from all isolates and their deduced amino acid sequences belonged to glycosyl hydrolase family 5. Among the domains of different isolates, the catalytic domains exhibited the highest homology of 93.7%, whereas the regions of signal, leader, linker, and carbohydrate-binding domain indicated low homology (73-74%). These variations in sequence homology are significant and could contribute to the structure and function of the enzyme.

      • KCI등재

        Solid Freeform Techniques Application in Bone Tissue Engineering for Scaffold Fabrication

        Saurabh Shivalkar,Sangeeta Singh 한국조직공학과 재생의학회 2017 조직공학과 재생의학 Vol.14 No.3

        Solid freeform techniques are revolutionising technology with great potential to fabricate highly organized biodegradable scaffolds for damaged tissues and organs. Scaffolds fabricated via Solid freeform (SFF) techniques have more pronounced effect in bone tissue engineering. SFF techniques produce various types of scaffolds from different biomaterials with specific pore size, geometries, orientation, interconnectivity and anatomical shapes. Scaffolds needs to be designed from such biomaterials which can attach directly to natural tissues and mimic its properties, so ideally mechanical properties of scaffolds should be same as that of regenerating tissues for best results. The scaffolds designed without optimized mechanical properties would lead to the reduced nutrition diffusion within tissue engineered constructs (TECs) causing tissue necrosis. These scaffolds are mainly processed from ceramics and polymers like calcium phosphate, polydioxane, €-polycaprolactone, polylactic and polyglycolic acids etc. While, hydrogel scaffolds provide bridge for encapsulated cells and tissues to integrate with natural ECM. Likewise, 2D images from radiography were not sufficient for the prediction of the brain structure, cranial nerves, vessel and architecture of base of the skull and bones, which became possible using the 3D prototyping technologies. Any misrepresentation can lead to fatal outcomes. Biomodelling from these techniques for spinal surgery and preoperative planning are making its way toward successful treatment of several spinal deformities and spinal tumor. In this review we explored laser based and printing SFF techniques following its methodologies, principles and most recent areas of application with its achievements and possible challenges faced during its applications.

      • SCOPUSKCI등재

        Novel Approach for Deriving Test Scenarios and Test Cases from Events

        ( Sandeep K Singh ),( Sangeeta Sabharwal ),( J P Gupta ) 한국정보처리학회 2012 Journal of information processing systems Vol.8 No.2

        Safety critical systems, real time systems, and event-based systems have a complex set of events and their own interdependency, which makes them difficult to test ma Safety critic Safety critical systems, real time systems, and event-based systems have a complex set of events and their own interdependency, which makes them difficult to test manually. In order to cut down on costs, save time, and increase reliability, the model based testing approach is the best solution. Such an approach does not require applications or codes prior to generating test cases, so it leads to the early detection of faults, which helps in reducing the development time. Several model-based testing approaches have used different UML models but very few works have been reported to show the generation of test cases that use events. Test cases that use events are an apt choice for these types of systems. However, these works have considered events that happen at a user interface level in a system while other events that happen in a system are not considered. Such works have limited applications in testing the GUI of a system. In this paper, a novel model-based testing approach is presented using business events, state events, and control events that have been captured directly from requirement specifications. The proposed approach documents events in event templates and then builds an event-flow model and a fault model for a system. Test coverage criterion and an algorithm are designed using these models to generate event sequence based test scenarios and test cases. Unlike other event based approaches, our approach is able to detect the proposed faults in a system. A prototype tool is developed to automate and evaluate the applicability of the entire process. Results have shown that the proposed approach and supportive tool is able to successfully derive test scenarios and test cases from the requirement specifications of safety critical systems, real time systems, and event based systems.

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