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Genotypic Diversity of Multidrug Resistant Shigella species from Iran
Sajjad Zamanlou,Mohammad Ahangarzadeh Rezaee,Mohammad Aghazadeh,Reza Ghotaslou,Hossein Hosseini Nave,Younes Khalili 대한감염학회 2018 Infection and Chemotherapy Vol.50 No.1
Background: In many developing countries, shigellosis is endemic and also occurs in epidemics and treatment of multidrug-resistant (MDR) isolates are important. The aims of this study were to determine the antimicrobial susceptibility, prevalence of class 1 and 2 integrons and the clonal relatedness of isolates. Materials and Methods: Antimicrobial susceptibility tests were performed by disc diffusion method. Polymerase chain reaction (PCR)-sequencing technique was employed for detection and characterization of integrons. The genetic relatedness was evaluated by using enterobacterial repetitive intergenic consensus (ERIC) PCR. Results: There was a high percentage of resistance to trimethoprim-sulfamethoxazole (TMP/SMX) (93.7%), ampicillin (AMP) (87.3%), streptomycin (STR) (84.5%) and tetracycline (TET) (78.9%). MDR phenotype was seen in 95.1% of total isolates. Most common MDR profile was TMP/SMX/STR/AMP resistant pattern. Among the 142 Shigella spp. analyzed in this study, 28 isolates were positive for class 1 integron with two types of gene cassette arrays (dfrA17/aadA5 = 31.7% and dfrA7 = 3.8%). The class 2 integron was more frequently detected among the isolates (94.7%) with dfrA1/sat1/aadA1 (69.4%) and dfrA1/sat1 (30.6%) gene cassettes. ERIC-PCR results showed 6, 5, 4 and 3 main genotypes among S. flexneri, S. sonnei, S. boydii and S. dysenteriae isolates, respectively. Conclusion: Our findings revealed that multidrug resistant Shigella species with high prevalence of class 2 integron were very common in Iran. In addition, ERIC-PCR patterns showed limited variety of clones are responsible for shigellosis in the region of the study.
Sajjad Dehghanpour,Keivan Hosseini Safari,Farzan Barati,Mohammadmahdi Attar 대한기계학회 2019 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.33 No.10
The objective of this study is to examine the stress concentration factor around a pin-loaded hole in a metallic matrix composite material, analytically and numerically. It is assumed that all unidirectional fibers lie in the metallic matrix while the shear stress in fibers is discarded. To generally derive the equilibrium equation for all fibers and the metallic matrix, the previous shear-lag theory had been improved and the extension in the metallic matrix was considered. Afterwards, the equilibrium equation was solved by the eigenvalue method while the displacement field and stress distribution around the pin-loaded hole were computed. Having calculated stress concentration factors and the displacement field in a unidirectional multi-layered composite material, we compared the analytical results with those numerical values from other references. Additionally, the effect of the pin’s diameter, as well as the edge-hole distance on maximum stress concentration factor was investigated. To recapitulate, it is seen that the modified shear-lag theory can simulate the mechanism of the load transfer between metallic matrices.
Sajjad Hamkari,Majid Moradzadeh,Elyas Zamiri,Mehdi Nasiri,Seyed Hossein Hosseini 전력전자학회 2017 JOURNAL OF POWER ELECTRONICS Vol.17 No.3
In this study a new high step-up dc-dc converter is presented. The operation of the proposed converter is based on the capacitor switching and coupled inductor with a single active power switch in its structure. A passive voltage clamp circuit with two capacitors and two diodes is used in the proposed converter for elevating the converter's voltage gain with the recovered energy of the leakage inductor, and for lowering the voltage stress on the power switch. A switch with a low (on) DS R can be adopted to reduce conduction losses. In the generalized mode of the proposed converter, to reach a desired voltage gain, capacitor stages with parallel charge and series discharge techniques are extended from both sides of secondary side of the coupled inductor. The proposed converter has the ability to alleviate the reverse recovery problem of diodes with circuit parameters. The operating principle and steady-states analyses are discussed in detail. A 40W prototype of the proposed converter is implemented in the laboratory to verify its operation.
Hamkari, Sajjad,Moradzadeh, Majid,Zamiri, Elyas,Nasir, Mehdi,Hosseini, Seyed Hossein The Korean Institute of Power Electronics 2017 JOURNAL OF POWER ELECTRONICS Vol.17 No.3
In this study a new high step-up dc-dc converter is presented. The operation of the proposed converter is based on the capacitor switching and coupled inductor with a single active power switch in its structure. A passive voltage clamp circuit with two capacitors and two diodes is used in the proposed converter for elevating the converter's voltage gain with the recovered energy of the leakage inductor, and for lowering the voltage stress on the power switch. A switch with a low $R_{DS}$ (on) can be adopted to reduce conduction losses. In the generalized mode of the proposed converter, to reach a desired voltage gain, capacitor stages with parallel charge and series discharge techniques are extended from both sides of secondary side of the coupled inductor. The proposed converter has the ability to alleviate the reverse recovery problem of diodes with circuit parameters. The operating principle and steady-states analyses are discussed in detail. A 40W prototype of the proposed converter is implemented in the laboratory to verify its operation.
Farnaz Hosseini,Sajjad Mohebbi 한국공업화학회 2020 Journal of Industrial and Engineering Chemistry Vol.85 No.-
Photocatalytic reduction of Zn2+, Cu2+ and Pb2+ ions were performed using modified titanium dioxidenanoparticles with histidine (His) and imidazole (IM) as the modifier and characterized by FT-IR, X-RD,FESEM, EDAX, TEM and A.A.S. techniques. The anatase phase titanium dioxide nanoparticles with the sizedistribution of 25–45 nm were obtained by the Sol–Gel Method. In the case of Cu2+, the reduction reactionwas completed in 10 min. The photo-reduction yields of Pb2+ and Zn2+ ions achieved to 98% removalduring 60 and 160 min, respectively. The immobilized modifiers on the TiO2 surface accelerate theelectron transfer from TiO2 to the metal ion via imidazole bridge upon ultraviolet light irradiation. Thisphotocatalytic reduction could be proceeded through chemisorption, reduction and desorption processesof metal ions on the surface of modified TiO2, sequentially and repeatably. Herein, methanol was playedas an artificial electron donor. These hybrid photocatalysts were reused several times without losingefficiency while the highest reduction yield was achieved for TiO2@His NPs. So, modified TiO2 with aminoacids could be an excellent candidate for metal ion reduction by an inexpensive method with advantagesof high performance, high activity, reusability, easily prepared, easily separate, environmentally friendlyand short reaction time.
Meysam Olfatifar,Seyed Mehdi Hosseini,Payam Shokri,Soheila Khodakarim,Naghmeh Khadembashi,Sajjad Rahimi Pordanjani 한국역학회 2020 Epidemiology and Health Vol.42 No.-
OBJECTIVES: Spatial information makes a crucial contribution to enhancing and monitoring the brucellosis surveillance system by facilitating the timely diagnosis and treatment of brucellosis. METHODS: An exponential scan statistic model was used to formalize the spatial distribution of the adjusted delay in the diagnosis time of brucellosis (time between onset and diagnosis of the disease) in Kurdistan Province, Iran. Logistic regression analysis was used to compare variables of interest between the clustered and non-clustered areas. RESULTS: The spatial distribution of clusters of human brucellosis cases with delayed diagnoses was not random in Kurdistan Province. The mean survival time (i.e., time between symptom onset and diagnosis) was 4.02 months for the short spatial cluster, which was centered around the city of Baneh, and was 4.21 months for spatiotemporal clusters centered around the cities of Baneh and Qorveh. Similarly, the mean survival time for the long spatial and spatiotemporal clusters was 6.56 months and 15.69 months, respectively. The spatial distribution of the cases inside and outside of clusters differed in terms of livestock vaccination, residence, sex, and occupational variables. CONCLUSIONS: The cluster pattern of brucellosis cases with delayed diagnoses indicated poor performance of the surveillance system in Kurdistan Province. Accordingly, targeted and multi-faceted approaches should be implemented to improve the brucellosis surveillance system and to reduce the number of lost days caused by delays in the diagnosis of brucellosis, which can lead to long-term and serious complications in patients.
Effect of Chlorella vulgaris on Liver Function Biomarkers: a Systematic Review and Meta-Analysis
( Samira Yarmohammadi ),( Reza Hosseini-ghatar ),( Sahar Foshati ),( Mojgan Moradi ),( Niloofar Hemati ),( Sajjad Moradi ),( Mohammad Ali Hojjati Kermani ),( Mohammad Hosein Farzaei ),( Haroon Khan ) 한국임상영양학회 2021 Clinical Nutrition Research Vol.10 No.1
This study presents a comprehensive systematic review and meta-analysis of randomized controlled trials (RCTs) on Chlorella vulgaris (C. vulgaris) supplementation and liver function biomarkers. Pertinent studies were identified using Scopus, ISI Web of Science, PubMed, and Cochrane library databases up to August 2020. Mean differences were pooled using a random-effects model. Pooling 7 RCTs together showed that C. vulgaris supplementation led to a significant reduction of serum aspartate aminotransferase (AST) levels (weighted mean difference [WMD], -9.15 U/L; 95% confidence interval [CI], -16.09, -2.21), but not alanine aminotransferase (ALT) or alkaline phosphatase (ALP) levels compared to the placebo consumption. Subgroup-analysis indicated that C. vulgaris supplementation had more effect on AST decreasing among non-alcoholic fatty liver disease patients (WMD, -16.42 U/L; 95% CI, -29.75, -3.09) than others. Furthermore, subgroup analysis based on kind of supplementation showed that C. vulgaris supplementation significantly decreased ALT levels (WMD, -4.65 U/L; 95% CI, -8.88, -0.42) compared with the placebo, but not metformin consumption. It seems that C. vulgaris supplementation mainly affects AST levels rather than ALT and ALP levels, however, as mentioned the effect of C. vulgaris on those enzymes might be context-dependent. Therefore, further investigations with a large number of patients as well as on different disorders are necessary and can provide more definitive evidence.
Coronavirus disease 2019 in a 13-year-old patient with acute lymphoblastic leukemia
Hossaini, Seyed Kamal Eshagh,Movahedi, Zahra,Hormati, Ahmad,Heydari, Hosein,Hosseini, Seyed Jalal Eshagh,Khodadust, Fatemeh,Afifian, Mahboubeh,Ahmadpour, Sajjad The Korean Pediatric Society 2021 Clinical and Experimental Pediatrics (CEP) Vol.64 No.5