Effect of Route of Preoperative Biopsy on Endoscopic Submucosal Dissection for Patients with Early Gastric Cancer

Jiang, Hui,Tu, Hui-Ming,Qiao, Qiao,Xu, Ke-Bin,Li, Jie,Qi, Xiao-Wei,Ge, Xiao-Song Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.20

Objective: To observe and compare the effects of multi-patch biopsy under conventional white light imaging endoscopy (C-WLI) and precise targeted biopsy under magnifying narrow-band imaging endoscopy (M-NBI) on the endoscopic submucosal dissection (ESD) of early gastric cancers and intraepithelial neoplasias. Methods: According to the way of selecting biopsy specimens, patients were divided into C-WLI and M-NBI groups, 20 cases. The ESD operations of the 2 groups were compared quantitively. Results: The mean frequency of biopsy in M-NBI group was ($1.00{\pm}0.00$), obviously lower than in the C-WLI group ($4.78{\pm}1.02$) (P<0.01).The average total number of selected biopsy specimens was also fewer ($1.45{\pm}0.12$ and $7.82{\pm}2.22$, respectively, P<0.01). There was no significant difference in the time of determining excision extension, marking time and the time of specimen excision of 2 groups during the ESD (P>0.05), whereas submucosal injection time, mucosal dissection time, stopping bleeding time, wound processing time in the M-NBI group were significantly shorter than in the C-WLI group (P<0.01). Conclusion: Precise targeted biopsy under M-NBI can obviously shorten the time of ESD operation, with small quantity of tissues but high pathological positive rate.

Ceratovacuna atrovirensa Qiao, a new species from China (Aphididae: Hormaphdinae)

Jiang Li-Yun,Chen Jing,Xu Ying,Qiao Ge-xia 한국응용곤충학회 2021 Journal of Asia-Pacific Entomology Vol.24 No.3

Ceratovacuna atrovirensa Qiao sp.n., a woolly aphid on Indocalamus tessellatus from China, is described and illustrated. The new species is supported by both morphological and molecular data. An updated key to apterous viviparous females of Ceratovacuna is provided. The type specimens are deposited in the National Zoological Museum of China, Institute of Zoology, the Chinese Academy of Sciences, Beijing, China and the Natural History Museum, London, United Kingdom.

The Research on Development of China’s Strategic Marine Emerging Industry Based on Grey System Theory

강교언(Qiao-Yan Jiang),김재봉(Jae-Bong Kim) 한국해양비즈니스학회 2017 해양비즈니스 Vol.- No.37

The 21st century is named marine century since the maritime economy has played an important role in global and regional economic development. This paper attempts to analyze China’s strategic marine emerging industries, applying the grey relative analysis method which fits the situation of less data and poor information. Firstly, we analyze the correlation between output value of China’s marine industry and the three main marine industries, which reach the result that the marine secondary and tertiary industry have more closely relation with the marine economy. Then, the sub-industry of the marine secondary and tertiary industry is listed to analyze the correlation between specific marine industry and marine economy. Next, according to the definition and characteristics of strategic marine emerging industry, the offshore oil and gas industry, marine scientific research & education management and other five industries are selected as China’s strategic marine emerging industry. Finally, it concludes and suggests to develop China’s strategic marine emerging industry in the future, which are to formulate the scientific policy system, to establish marine industrial concentration area, to improve marine ecological awareness and to focus on talent training specialized in strategic marine emerging industry. The present study embodies the application of grey system theory in analyzing China’s marine economic development which contributes to provide theoretical basis and practical references for choosing strategic marine industry scientifically.

D-RADA16-RGD-Reinforced Nano-Hydroxyapatite/Polyamide 66 Ternary Biomaterial for Bone Formation

Bo Qiao,Bin He,Ao Zhou,Yuling Li,Xiaojun Chen,Qiming Yang,Beike Chen,Bo Qiao,Dianming Jiang 한국조직공학과 재생의학회 2019 조직공학과 재생의학 Vol.16 No.2

BACKGROUND: Nano-hydroxyapatite/polyamide 66 (nHA/PA66) is a composite used widely in the repair of bone defects. However, this material is insufficient bioactivity. In contrast, D-RADA16-RGD self-assembling peptide (DRADA16- RGD sequence containing all D-amino acids is Ac-RADARADARADARADARGDS-CONH2) shows admirable bioactivity for both cell culture and bone regeneration. Here, we describe the fabrication of a favorable biomaterial material (nHA/PA66/D-RADA16-RGD). METHODS: Proteinase K and circular dichroism spectroscopy were employed to test the stability and secondary structural properties of peptide D-RADA16-RGD respectively. Scanning electron microscopy (SEM) and transmission electron microscopy (TEM) were used to characterize the surface of these materials. Confocal laser scanning (CLS), cell counting kit-8 tests (CCK-8), alizarin red S staining, cell immunofluorescence analysis and Western blotting were involved in vitro. Also biosafety and bioactivity of them have been evaluated in vivo. RESULTS: Proteinase K and circular dichroism spectroscopy demonstrated that D-RADA16-RGD in nHA/PA66 was able to form stable-sheet secondary structure. SEM and TEM showed that the D-RADA16-RGD material was 7–33 nm in width and 130–600 nm in length, and the interwoven pore size ranged from 40 to 200 nm. CLS suggests that cells in nHA/PA66/ D-RADA16-RGD group were linked to adjacent cells with more actin filaments. CCK-8 analysis showed that nHA/PA66/ D-RADA16-RGD revealed good biocompatibility. The results of Alizarin-red S staining and Western blotting as well as vivo osteogenesis suggest nHA/PA66/D-RADA16-RGD exhibits better bioactivity. CONCLUSION: This study demonstrates that our nHA/PA66/D-RADA16-RGD composite exhibits reasonable mechanical properties, biocompatibility and bioactivity with promotion of bone formation.

Research on Query Gain Routing Algorithms and Load Balancing Mechanism in Wireless Sensor Networks

Jiang Hui-Lin,Qiao Li,Fu Yi-De 보안공학연구지원센터 2015 International Journal of Future Generation Communi Vol.8 No.2

It is necessary to reduce the consumption of network node energy and the network load for solving the query design for routing algorithm in wireless sensor network, thus this article presents query gain routing algorithms and load balancing mechanism. This algorithm selects routing node by querying the routing information of gain matrix according to the successful record of historical query. The load balancing mechanism queries the energy information, which records node in the routing process and transfers load to balance the energy consumption of each node in the query path. This algorithm is able to effectively aware routing load to reduce the network energy consumption and avoid the data collision. The experimental result shows that compared with other query routing strategy, the query gain routing can increase the success rate of query under the condition of reducing the node energy consumption, but the load balancing mechanism can reduce the energy consumption of query gain routing further and prolong the network life cycle more effectively.

Controlling the initial conditions of precursor powders and its effects on the phase evolution and $J_c$ properties of Bi-2223/Ag tapes

Jiang, C.H,Yoo, J.M,Kim, H.D,Kang, S.C,Chung, H.S,Wang, Y.Z,Ko, J.W,Qiao, G.W The Korean Superconductivity Society 2001 Progress in superconductivity Vol.3 No.1

By varying fabricating process, precursor powders with different initial conditions were prepared. Subsequently, Bi-2223/Ag tapes were made through these powders. The effects of precursor powders on the phase evolution and Jr properties of Bi-2223/Ag tapes were studied along with several thermomechanical cycles. Our results showed that the initial conditions of precursor powders could strongly influence the phase formation rate and $J_{c}$ value in final tapes. The factors of precursor powders that influence the phase formation and $J_{c}$ of Bi-2223/Ag tapes must be studied and optimized in combination.ion.

Comparison of Molecular Linkage Maps and QTLs for Morphological Traits in Two Reciprocal Backcross Populations of Rice

Qiao, Yongli,Jiang, Wenzhu,Rahman, Md Lutfor,Chu, Sang Ho,Piao, Rihua,Han, Longzhi,Koh, Hee Jong Korean Society for Molecular Biology 2008 Molecules and cells Vol.25 No.3

Comparison of maps and QTLs between populations may provide us with a better understanding of molecular maps and the inheritance of traits. We developed and used two reciprocal BC1F1 populations, IP/DS//IP and IP/DS//DS, for QTL analysis. DS (Dasanbyeo) is a Korean tongil-type cultivar (derived from an indica x japonica cross and similar to indica in its genetic make-up) and IP (Ilpumbyeo) is a Korean japonica cultivar. We constructed two molecular linkage maps corresponding to each backcross population using 196 markers for each map. The length of each chromosome was longer in the IP/DS//IP population than in the IP/DS//DS population, indicating that more recombinants were produced in the IP/DS//IP population. Distorted segregation was observed for 44 and 19 marker loci for the IP/DS//IP and IP/DS//DS populations, respectively; these were mostly skewed in favor of the indica alleles. A total of 36 main effect QTLs (M-QTLs) and 15 digenic epistatic interactions (E-QTLs) were detected for the seven traits investigated. The phenotypic variation explained (PVE) by M-QTLs ranged from 3.4% to 88.2%. Total PVE of the M-QTLs for each trait was significantly higher than that of the E-QTLs. The total number of M-QTLs identified in the IP/DS//IP population was higher than in the IP/DS//DS population. However, the total PVE by the M-QTLs and E-QTLs together for each trait was similar in the two populations, suggesting that the two BC1F1 populations are equally useful for QTL analysis. Maps and QTLs in the two populations were compared. Eleven new QTLs were identified for SN, SF, GL, and GW in this study, and they will be valuable in marker-assisted selection, particularly for improving grain traits in tongil-type varieties.

Fine Mapping and Candidate Gene Analysis of the Floury Endosperm Gene, FLO(a), in Rice

Qiao, Yongli,Lee, Song-I,Piao, Rihua,Jiang, Wenzhu,Ham, Tae-Ho,Chin, Joong-Hyoun,Piao, Zhongze,Han, Longzhi,Kang, Si-Yong,Koh, Hee-Jong Korean Society for Molecular and Cellular Biology 2010 Molecules and cells Vol.29 No.2

In addition to its role as an energy source for plants, animals and humans, starch is also an environmentally friendly alternative to fossil fuels. In rice, the eating and cooking quality of the grain is determined by its starch properties. The floury endosperm of rice has been explored as an agronomical trait in breeding and genetics studies. In the present study, we characterized a floury endosperm mutant, flo(a), derived from treatment of Oryza sativa ssp. japonica cultivar Hwacheong with MNU. The innermost endosperm of the flo(a) mutant exhibited floury characteristics while the outer layer of the endosperm appeared normal. Starch granules in the flo(a) mutant formed a loosely-packed crystalline structure and X-ray diffraction revealed that the overall crystallinity of the starch was decreased compared to wild-type. The FLO(a) gene was isolated via a map-based cloning approach and predicted to encode the tetratricopeptide repeat domaincontaining protein, OsTPR. Three mutant alleles contain a nucleotide substitution that generated one stop codon or one splice site, respectively, which presumably disrupts the interaction of the functionally conserved TPR motifs. Taken together, our map-based cloning approach pinpointed an OsTPR as a strong candidate of FLO(a), and the proteins that contain TPR motifs might play a significant role in rice starch biosynthetic pathways.

Relationships of uPA and VEGF Expression in Esophageal Cancer and Microvascular Density with Tumorous Invasion and Metastasis

Jiang, Jian-Tao,Zhang, Lan-Fang,Zhou, Bin,Zhang, Shun-Qun,Li, Shao-Min,Zhang, Wei,Zhang, Jin,Qiao, Zhe,Kong, Ran-Ran,Ma, Yue-Feng,Chen, Sheng Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.7

Objective: To investigate uPA and VEGF expression in esophageal cancer and relations with tumorous invasion and metastasis. Methods: Immunohistochemistry was used to detect uPA and VEGF expression in the normal epithelial tissue of esophageal mucosa and cancer tissue and detect CD34 labeled micrangium and analyze the relationships with clinical pathological features and tumor angiogenesis. Results: Positive rates for uPA and VEGF protein expression were significantly greater in esophageal cancer than normal epithelial tissue (P < 0.05), the two being linked (P <0.05). In addition, uPA and VEGF protein expression of the high microvessel density (MVD) group was significantly lower than in the low MVD group (P < 0.05), with relation to clinical pathological staging, differentiation and lymph node metastasis (P < 0.05). Conclusion: In esophageal cancer tissue, uPA and VEGF proteins are overexpressed and promote tumor angiogenesis, indicative of a poor prognosis.

Identification of QTLs for seed germination capability after various storage periods using two RIL populations in rice

Jiang, Wenzhu,Lee, Joohyun,Jin, Yong-Mei,Qiao, Yongli,Piao, Rihua,Jang, Sun Mi,Woo, Mi-Ok,Kwon, Soon-Wook,Liu, Xianhu,Pan, Hong-Yu,Du, Xinglin,Koh, Hee-Jong Springer-Verlag 2011 Molecules and cells Vol.31 No.4