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      • KCI등재

        A multifunctional lactic acid based plasticizer used for plasticizing PVC and PLA: Endowing PLA elastic restore capability

        Minjia Lu,Pingping Jiang,Pingbo Zhang,Shan Feng,Zhixuan Cui,Qingkui Song,Yong Zhao,Jingxian Shen,Yiyi Fan,Huixian Lu 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.128 No.-

        A novel multifunctional plasticizer, cyclohexyl triethylene glycol oligo-lactate (CTLE) was designed by atwo-step esterification reaction using green non-toxic biomass lactic acid as raw material. Its structurewas characterized by 1H NMR, FT-IR and TOF-MS. Thermogravimetric analysis (TGA), tensile test andleaching test were used to evaluate the plasticizer effect of PVC or PLA blends. Compared with commercialplasticizers, CTLE showed more outstanding thermal stability, flexibility and migration stability. Under the same condition with the addition of 50 phr plasticizer, the CTLE plasticized PVC film hadthe lowest glass transition temperature (TgCTLE-50 = 24.6 C) and the highest initial decomposition temperature(TiCTLE-50 = 265.4 C). In PLA blends, only the CTLE plasticized PLA film could recover after fracture,and the stress relaxation test results showed that the stress value of PLA-CTLE-20 drops sharply to anon-zero value, showing elastic characteristics. We estimate that the excellent plasticity of CTLE is due toits molecular structure. Among them, a large number of polar groups form intermolecular forces withPVC chain segments to make the binding tight, and the ring structure increases the free volume betweenPVC chain segments.

      • KCI등재

        Molecular mechanisms conferring asymmetrical cross-resistance between tebufenozide and abamectin in Plutella xylostella

        Qian Yin,Lu Qian,Pingping Song,Tunyu Jian,Zhao-Jun Han 한국응용곤충학회 2019 Journal of Asia-Pacific Entomology Vol.22 No.1

        Based on the confirmation of asymmetrical cross-resistance between abamectin and tebufenozide in Plutella xylostella, the present work proved that the cytochrome P450 monooxygenase plays a decisive role in crossresistance, and the expression of various cytochrome P450 (CYP450) genes in different strains was surveyed to elucidate the molecular basis of the underlying mechanisms. Enzyme analysis showed the activity of cytochrome P450 monooxygenase was notable enhanced in the strains resistant to both tebufenozide (3.07-fold) and abamectin (3.37-fold), suggesting that the enhancement of cytochrome P450 monooxygenase is the main detoxification mechanism responsible for the cross-resistance. CYP4M7 (64.58-fold) and CYP6K1 (41.97-fold) had extremely high expression levels in the Teb-R strain, selected using tebufenozide, which was highly resistant to tebufenozide (RR 185.5) and moderately cross-resistant to abamectin (RR 41.0). When this strain was subjected to further selection using abamectin, the resultant Aba-R strain showed a higher expression of CYP6K1 (60.32-fold). However, the expression of CYP4M7 was reduced (10.62-fold). Correspondingly, the Aba-R strain became more resistant to abamectin (RR 593.8) and less resistant to tebufenozide (RR 28.0). Therefore, we concluded that the over expression of CYP4M7 was the main cause for tebufenozide resistance, and that CYP6K1 mainly conferred abamectin resistance. The asymmetrical cross-resistance occurred because tebufenozide selection not only enhanced the expression of CYP4M7, but also that of CYP6K1. This is the first report on the molecular mechanism of asymmetrical cross-resistance between insecticides.

      • KCI등재

        Development and Application of Three-Dimensional Bioprinting Scaffold in the Repair of Spinal Cord Injury

        Lu Dezhi,Yang Yang,Zhang Pingping,Ma Zhenjiang,Li Wentao,Song Yan,Feng Haiyang,Yu Wenqiang,Ren Fuchao,Li Tao,Zeng Hong,Wang Jinwu 한국조직공학과 재생의학회 2022 조직공학과 재생의학 Vol.19 No.6

        Spinal cord injury (SCI) is a disabling and destructive central nervous system injury that has not yet been successfully treated at this stage. Three-dimensional (3D) bioprinting has become a promising method to produce more biologically complex microstructures, which fabricate living neural constructs with anatomically accurate complex geometries and spatial distributions of neural stem cells, and this is critical in the treatment of SCI. With the development of 3D printing technology and the deepening of research, neural tissue engineering research using different printing methods, bio-inks, and cells to repair SCI has achieved certain results. Although satisfactory results have not yet been achieved, they have provided novel ideas for the clinical treatment of SCI. Considering the potential impact of 3D bioprinting technology on neural studies, this review focuses on 3D bioprinting methods widely used in SCI neural tissue engineering, and the latest technological applications of bioprinting of nerve tissues for the repair of SCI are discussed. In addition to introducing the recent progress, this work also describes the existing limitations and highlights emerging possibilities and future prospects in this field.

      • KCI등재후보

        Edible composite films: enhancing the postharvest preservation of blueberry

        Shi Dongfang,Zhao Boya,Zhang Pingping,Li Ping,Wei Xinpei,Song Kai 한국원예학회 2024 Horticulture, Environment, and Biotechnology Vol.65 No.3

        Blueberry is popular among consumers for their unique fl avor and rich nutritional content. However, fresh blueberry often has a short shelf life due to microbial contamination and water loss. Existing blueberry preservation methods, such as irradiation, air conditioning, and high-voltage electrostatic fi elds, have shown certain eff ectiveness. Nonetheless, their high cost and energy consumption limit their widespread use. Edible composite fi lms, created by incorporating functional substances into an edible fi lm matrix, represent an eco-friendly preservation technology. These fi lms alter the surface microenvironment of fruits by establishing a selective barrier on the fruit's surface, which signifi cantly enhances fruit storage quality. This article provides a comprehensive review of the application of edible composite fi lms in blueberry preservation. By summarizing the spoilage process of blueberry during harvesting and storage, in conjunction with fruit preservation techniques, it explores the feasibility and potential applications of edible composite fi lms. Lastly, it delves into the possibilities and challenges of integrating nanomaterials with edible composite fi lms.

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