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Concurrent Relations of Commodity Futures
Namkoong,Hongseok,Kim, Woochang 대한산업공학회 2011 대한산업공학회 추계학술대회논문집 Vol.2011 No.11
Literatures have focused on the relationship between basis, cost of storage and convenience yield, as given by the Theory of Storage. However, the relations among futures contracts should be considered as a whole, upon discussion of futures-spot relationships: futures curve reflects inventory level and the risk premium and thus the dynamics of future spot price. Here the predictive ability of the futures curve over future spot price dynamics is empirically proven. When the futures curve is highly volatile, market participants’ expectation on inventory and risk premium vary. As this discrepancy widen, spot inventory is deemed unstable. Thus, spot price rises for a short time. But then, as inventory restores itself, spot mean reverts, making a sharp market correction. An investment strategy that predicts spot price crashes using the futures curve is devised. Equal weight portfolio of 26 commodities is used. Results corroborate the conjecture; it predicts major market crashes. Result indicates that contemporary relations among futures contracts are crucial in futures-spot relationships. This result expands the view offered by the Theory of Storage by highlighting the importance of relationship among futures contracts.
김유철,남궁재관 한국산업안전학회 1994 한국안전학회지 Vol.9 No.1
Ultrasonic for MoSi₂/Y. C. Kim, C. K. Namkoong/MoSi₂ in the silicides has excellence in the oxidation and corrosion resistence. When the solid state bonding sintered-MoSi₂/metal or the thermal sprayed coating by powder-MoSi₂ on the metal are carried out, the defects may be occured at the bonded surface. So, the method for evaluating the existence of the defects by non-destructive inspection is strongly desired. Here, the characteristics of ultrasonic for sintered-MoSi₂ are elucidated and the possibility of the detection of defects using by ultrasonic is investigated.
Central administration of GLP-1 and GIP decreases feeding in mice
NamKoong, C.,Kim, M.S.,Jang, B.T.,Lee, Y.H.,Cho, Y.M.,Choi, H.J. Academic Press 2017 Biochemical and biophysical research communication Vol. No.
Glucagon-like peptide-1 amide (GLP-1) and gastric inhibitory polypeptide (GIP) are incretin hormones regulating energy metabolism. GLP-1 and GIP combination is suggested as a promising therapeutic strategy for treatment of obesity and diabetes. However, the neuronal mechanisms are not yet investigated. In the present study, we investigated the role of central GLP-1 and GIP in regulation of body weight homeostasis. The effect of GLP-1 with GIP on food intake, body weight, locomotor activity were determined following intracerebroventricular (ICV) administration of GLP-1 and/or GIP in mice. ICV administration of low dose GLP-1 (0.3 nmol) and GIP (1 and 3 nmol) did not change food intake. However, ICV administration of higher doses GLP-1 (1 and 3 nmol) and GIP (6 nmol) significantly decreased food intake and body weight. To investigate the synergic effect of ICV GLP-1 and GIP, subeffective dose GLP-1 (0.3 nmol) and subeffective dose GIP (1 nmol) were chosen for further co-administration study. ICV co-administration of GLP-1 and GIP significantly decreased food intake, body weight and drinking. ICV co-administration of GLP-1 and GIP significantly increased neuronal activation and pro-opiomelanocortin (POMC) expression in hypothalamic arcuate nucleus. The neuronal activation and POMC expression were observed in two distinct neuronal populations. These results provide neuronal mechanisms supporting the development of GLP-1 and GIP combination therapeutics for treatment of obesity and diabetes.
Effect of anti-muscarinic autoantibodies on leukocyte function in Sjögren’s syndrome
Namkoong, Eun,Lee, Sang-woo,Kim, Nahyun,Choi, Youngnim,Park, Kyungpyo 3M Company 2017 Molecular immunology Vol.90 No.-
<P>Our results suggest that anti-M3R autoantibodies in primary Sjogren's syndrome induce downregulation of plasma membrane-resident M3R and MHC class I molecules in leukocytes followed by NK cell-mediated cell death. This mechanism may explain the frequency of leukopenia occurrence in patients with primary Sjogren's syndrome.</P>
Precancerous Conditions of Uterine Cervix and its Relation to Trichomonal Infection
Namkoong, Sung Eun,Kim, Seung Jo,Lee, Yong Seon,Kim, Yoon Ho,Kim, Sun Moo CATHOLIC MEDICAL CENTER 1979 Bulletin of the Clinical Research Institute Vol.7 No.1
Trichomonas Vaginalis, first described by Donne, 1836, for many years has been associated with lesions of the female genital tract.
Effect of Probenecid on the Biliary Excretion of Belotecan
NamKoong, Eun-Mi,Kim, In-Wha,Kim, Dae-Duk,Chung, Suk-Jae,Shim, Chang-Koo 대한약학회 2007 Archives of Pharmacal Research Vol.30 No.11
The purpose of this study was to investigate the effect of probenecid, an inhibitor of the MRP2/ABCC transporter, on the pharmacokinetics and transport of belotecan (7-[2-(N-isopropy-lamino)ethyl]-(20S)-camptothecin). The effect of probenecid on the pharmacokinetics of belotecan was studied in rats. When belotecan was injected as a bolus dose of 5 mg/kg after probenecid was infused at a rate of 42.8 mg/2 mL/h/kg, the cumulative biliary excretion amounts and biliary clearance $(CL_b)$ of belotecan decreased ($28.29{\pm}2.83$ versus $19.96{\pm}1.45%$ of dose and $161.01{\pm}26.95$ versus $92.66{\pm}1.45$ mL/min/kg), whereas the systemic pharmacokinetics did not change. This indicates that the MRP2 transporter is involved in the biliary excretion of belotecan. The involvement of MRP2 in the secretory transport was further characterized using Caco-2 cell monolayers expressing MRP2. The apparent permeability across Caco-2 cell monolayers from basolateral to apical was 2.3 times greater than that from the apical to the basolateral side at the $50{\mu}M$ belotecan. In addition, probenecid significantly decreased the basolateral-to-apical transport of belotecan (52.9%). These results indicate that MRP2 is involved in the secretory transport of belotecan in biliary excretion.
Contour machining error in NC milling process
Namkoong, Chaikwan,Yellowley, I. 한국공작기계학회 2001 한국생산제조학회지 Vol.10 No.6
The comprehensive system analysis for contour milling operation has performed in this study, which combined the each element with proper connectivity into closed loop system, and determined the system response by numerical simulation technique. The obtained simulated results were then compared with the experimental results from the practical points of view, and so forth, the governing equations were formulated into the estimation model, which predicted the total contour machining error within 25% accuracy. Through the procedural evaluation, it could ascertain the characteristics of generation mechanics in circular contour machining error, and the weight of each factor.