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- 저자 : Morrow, G. (검색결과 33 건)
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Feeding Orange Pulp Improved Bone Quality in a Rat Model of Male Osteoporosis
Morrow, Rori,Deyhim, Farzad,Patil, Bhimanagouda S.,Stoecker, Barbara J. The Korean Society of Food Science and Nutrition 2009 Journal of medicinal food Vol.12 No.2
Oxidative stress and inflammation have been linked to bone loss. We evaluated the effects of feeding orange pulp (OP), a source of vitamin C and flavonoids, on bone quality in a rat model of male osteoporosis. One-year-old retired breeder rats (n = 43) were orchidectomized (ORX) or sham-operated (SHAM). Three days postsurgery, ORX rats were randomly assigned to treatments: ORX or ORX with 2.5% OP, 5% OP, or 10% OP. Diets were isonitrogenous, isocaloric, modified AIN-93M diets with equal fiber content. All ORX rats were fed for 4 months to the mean food intake of the SHAM group. At the end of the study blood, urine and bone samples were collected. Plasma antioxidant capacity and urinary deoxypyridinoline (DPD) were determined. Bone density, structure, and strength were assessed using dual energy X-ray absorptiometry, microcomputed tomography, and finite element analyses. ORX decreased (P < .05) antioxidant status, while OP as low as 2.5% maintained the antioxidant capacity of ORX rats comparable to that of the SHAM group. Cortical thickness at the tibial midshaft was significantly decreased by ORX and increased by OP, and urinary DPD was significantly increased by ORX and decreased by OP. In fourth lumbar trabecular cores, ORX rats had significantly reduced bone volume fraction, connectivity density, and trabecular number and increased trabecular separation. OP significantly increased bone volume fraction and trabecular number and decreased trabecular separation in ORX rats. Improvements due to OP in microarchitectural properties of vertebral bones and in cortical thickness of long bones were subtle but significant. The consistently negative impacts of ORX on bone density, structure, and strength parameters confirm the previously reported importance of testosterone for bone.
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Morrow, Thomas A.,Mittelstaedt, Eric,Kim, Seung-Sep Elsevier 2019 Earth and planetary science letters Vol.512 No.-
<P><B>Abstract</B></P> <P>Between 150°W and 135°W, the Clarion Fracture Zone (FZ) coalesces from six discrete FZ traces to a single FZ over a period of ∼30 million years, coinciding with a change in plate motion that placed the associated transform fault (TF) in compression. Between 160° and 157°, the Murray FZ is also comprised of several closely-spaced (<50 km) discrete FZs and the associated TF experienced similar transpressional motion. Analysis of newly collected bathymetry data along the Clarion and Murray FZs reveals FZ structures that are inconsistent with predictions from a simple locked fault thermal subsidence model. These structures include FZ-bounded lithosphere that dips towards the old side of the FZ, whereas locked fault models predict it should dip towards the young side, and reversed fault scarp relationships where younger lithosphere lies deeper than older lithosphere. We investigate these anomalous observations using a combination of analytical and numerical models of two closely-spaced fracture zones to test how FZ strength and tectonic motions (compression or extension) affect the evolution of the intra-transform lithosphere. Our models predict that interior blocks within a segmented FZ, initially in isostatic equilibrium, can develop anomalous tilts and scarp depth relationships if the intervening FZs are relatively weak. Model results suggest that unusually low apparent coefficients of friction (<0.01) and tectonic compression are required to reproduce the magnitude of reverse tilt and scarp reversals observed in the Clarion and Murray FZs. We suggest that these low apparent friction coefficients might be the result of near lithostatic pore-fluid pressures associated with compression and alteration processes. Our results provide a tool to constrain histories of tectonic compression across FZs in places where rotation poles or other measures of plate motion may not be well constrained. Our results also imply that FZs are tectonically weak regions of hydrothermal alteration that may carry large volumes of volatiles into the mantle when subducted.</P> <P><B>Highlights</B></P> <P> <UL> <LI> New bathymetry at two FZs reveals structures inconsistent with locked fault models. </LI> <LI> Numerical and analytical models suggest features require weak fracture zones. </LI> <LI> Required weakness suggests pore fluid pressures approaching lithostatic values in FZ. </LI> </UL> </P>
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POSSIBLE WORLD BANK ASSISTANCE TO NORTH KOREA: ISSUES AND CHALLENGES
Daniel Morrow 경남대학교 극동문제연구소 2006 ASIAN PERSPECTIVE Vol.30 No.3
Accepting the DPRK as a member of the World Bank would require the political support of most of the Bank’s member governments, and this would become possible only if there is a successful resolution of the Six-Party Talks. The amount of financial assistance from the Bank would then depend on how seriously the DPRK pursues a transition to a more open and market-oriented economy, but in any case the Bank’s financial assistance would be small compared to the DPRK’s needs and to the potential assistance from bilateral sources. Nevertheless, the World Bank’s policy advice and its potential role in coordinating and catalyzing other assistance could be important for North Korean economic development. The prospects for quickly launching a constructive relationship between the DPRK and the World Bank following a successful conclusion of the Six-Party Talks would be enhanced by advanced preparation on both sides. In particular, the DPRK should begin to articulate its own strategy for economic transition.
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Feeding Orange Pulp Improved Bone Quality in a Rat Model of Male Osteoporosis
Rori Morrow,Farzad Deyhim,Barbara J. Stoecker,Bhimanagouda S. Patil 한국식품영양과학회 2009 Journal of medicinal food Vol.12 No.2
Oxidative stress and inflammation have been linked to bone loss. We evaluated the effects of feeding orange pulp (OP), a source of vitamin C and flavonoids, on bone quality in a rat model of male osteoporosis. One-year-old retired breeder rats (n = 43) were orchidectomized (ORX) or sham-operated (SHAM). Three days postsurgery, ORX rats were randomly assigned to treatments: ORX or ORX with 2.5% OP, 5% OP, or 10% OP. Diets were isonitrogenous, isocaloric, modified AIN-93M diets with equal fiber content. All ORX rats were fed for 4 months to the mean food intake of the SHAM group. At the end of the study blood, urine and bone samples were collected. Plasma antioxidant capacity and urinary deoxypyridinoline (DPD) were determined. Bone density, structure, and strength were assessed using dual energy X-ray absorptiometry, microcomputed tomography, and finite element analyses. ORX decreased (P < .05) antioxidant status, while OP as low as 2.5% maintained the antioxidant capacity of ORX rats comparable to that of the SHAM group. Cortical thickness at the tibial midshaft was significantly decreased by ORX and increased by OP, and urinary DPD was significantly increased by ORX and decreased by OP. In fourth lumbar trabecular cores, ORX rats had significantly reduced bone volume fraction, connectivity density, and trabecular number and increased trabecular separation. OP significantly increased bone volume fraction and trabecular number and decreased trabecular separation in ORX rats. Improvements due to OP in microarchitectural properties of vertebral bones and in cortical thickness of long bones were subtle but significant. The consistently negative impacts of ORX on bone density, structure, and strength parameters confirm the previously reported importance of testosterone for bone.
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Current Practices in the Assessment of Quality of Life in Individuals with Aphasia
K. Leigh Morrow-Odom,Dana C. Moser,Jean Neils-Strunjas 한국언어재활사협회 2017 Clinical Archives of Communication Disorders Vol.2 No.2
Purpose: The purpose of this study was to determine how speech-language pathologists (SLPs) in the United States are implementing recommendations regarding the assessment of quality of life (QoL) in persons with aphasia (PWA). Methods: A brief, anonymous survey was made available online using a web-based survey platform. Questions addressed demographics, training, importance of QoL assessment, current patterns of clinical practice, and perception of barriers. Data reported included frequency counts and percentages. Results: Sixty-two SLPs completed the survey in-part or in-full. The data suggest that the participants appreciate the importance of addressing QoL in PWA. Most participants indicated receiving instruction on QoL assessment in an academic setting, and about half reported completing continuing education on the topic. Interview and observation were most often used as the method of assessment, and few indicated using published measures. Information was elicited from a variety of sources, and QoL was most often assessed at the beginning and end of treatment, but seldom after discharge. QoL was less often assessed in those with severe and/or global aphasia. The most frequently reported barriers to assessing QoL were lack of training/knowledge and resources. Conclusions: It is hoped that these findings will help facilitate improved clinical care for persons with aphasia by encouraging SLPs to utilize currently available tools for assessing QoL in PWA and work to develop other tools and strategies for conducting QoL assessments throughout the rehabilitation process, including into the chronic stage of recovery, in order to optimize recovery.
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Rudolph M. Morrow,Gary E. McIlvian,Jenifer Johnson,Mark K. Timmons 대한견주관절학회 2022 대한견주관절의학회지 Vol.25 No.3
Background: Medial elbow laxity develops in throwing athletes due to valgus forces. Medial elbow instability in professional, collegiate, and high school athletes is well documented; however, the medial elbow of young throwing athletes has received less attention. This study investigated the medial elbow and common flexor tendon during applied elbow valgus stress of youth baseball players. Methods: The study included 15 participants. The medial elbow width and thickness of the common flexor tendon were measured on ultrasound images. Results: No significant side differences in medial elbow width or common flexor tendon were found at rest or under applied valgus stress. At rest, the medial elbow joint width was 3.34±0.94 mm on the dominant side and 3.42±0.86 mm on the non-dominant side. The dominant side increased to 3.83±1.02 mm with applied valgus stress, and the non-dominant side increased to 3.96±1.04 mm. The mean flexor tendon thickness was 3.89±0.63 mm on the dominant side and 4.02±0.70 mm on the non-dominant side. Conclusions: These findings differ from similar studies in older throwing athletes, likely because of the lack of accumulated stress on the medial elbow of youth throwing athletes. Maintaining elbow stability in young throwing athletes is a vital step to preventing injury later in their careers.
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