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Chikahiro Imashiro,Takashi Morikura,Motoaki Hayama,Atsushi Ezura,Jun Komotori,Shogo Miyata,Sakaguchi Katsuhisa,Shimizu Tatsuya 한국생물공학회 2023 Biotechnology and Bioprocess Engineering Vol.28 No.1
Various culture devices have been developed as fundamental technologies for facilitating bioengineering studies. Culture devices are designed to prepare specific culture environments. Thus, both macrostructures and surface micromorphology should be considered in the device design. Although fabricating devices with elaborate designs incurs high production costs, disposable materials are typically used for culture devices. However, some metallic materials are strong, stable, and biocompatible. Bioengineers have not applied these materials to culture devices because of the difficulty of processing. An emerging technology using three-dimensional (3D) printing has been developed, which can produce complex designs using metal. We demonstrate the applicability and potential of metal 3D printing for fabricating culture devices toward the development of the bioengineering discipline. As a specific example, we fabricated metallic culture devices where the environment of cultured tissues can be improved. One of the biggest factors determining the culture environment is active media supply. To attain active media supply to the tissue, devices having culture surfaces with mesh structures having holes far larger than cells were proposed. Cell sheets were cultured as tissue models, realizing tissue culture with such structures. The cultured tissue showed increased metabolism, indicating enhanced media supply owing to mesh surfaces. The biocompatibility of the 3D printed metal device was confirmed by viability assays on cultured cells, and reusability of the device was confirmed by mechanical and biochemical evaluations. We believe this study serves as a reference for using metallic 3D printing as an option for fabricating culture devices, which will promote bioengineering research.
Back out of Locking Pin with Hinge Fracture after High Tibial Osteotomy
( Shuhei Otsuki ),( Tomohiko Murakami ),( Rei Morikura ),( Kosuke Nakagawa ),( Yoshinori Okamoto ),( Masashi Neo ) 대한슬관절학회 2018 대한슬관절학회지 Vol.30 No.2
Low-profile fixation devices for medial opening wedge high tibial osteotomy (OWHTO) were developed in order to avoid skin irritation and additional invasion. However, the low-profile system is associated with additional risks. We report three cases of locking pin back out with the lowprofile locking plate system for medial OWHTO.
Stochastic Geometry Analysis of Normalized SNR-Based Scheduling in Downlink Cellular Networks
Ohto, Takuya,Yamamoto, Koji,Kim, Seong-Lyun,Nishio, Takayuki,Morikura, Masahiro IEEE 2017 IEEE wireless communications letters Vol.6 No.4
<P>The coverage probability and average data rate of normalized SNR-based scheduling in a downlink cellular network are derived by modeling the locations of the base stations and users as two independent Poison point processes. The scheduler selects the user with the largest instantaneous SNR normalized by the short-term average SNR. In normalized SNR scheduling, the coverage probability when the desired signal experiences Rayleigh fading is shown to be given by a series of Laplace transforms of the probability density function of interference. Also, a closed-form expression for the coverage probability is approximately achieved. The results confirm that normalized SNR scheduling increases the coverage probability due to the multi-user diversity gain.</P>
Performance Analysis of a Two-hop Wireless Relay Network with CSMA / CA and Network Coding
Chun-Hsiang Huang,Daisuke Umehara,Satoshi Denno,Masahiro Morikura,Takatoshi Sugiyama 대한전자공학회 2009 ITC-CSCC :International Technical Conference on Ci Vol.2009 No.7
In this paper, we provide an analytical model to compute the approximate throughput of a two-hop wireless relay network in which stations employ carrier sense multiple access with collision avoidance (CSMA/CA) protocol and network coding on the MAC layer. In addition, this model can be applied to the conventional CSMA/CA wireless relay network without network coding. Network coding is a highly regarded technology that is able to enhance the system capacity of multiple unicast and multisource multicast networks. Based on the assumption of no hidden terminals, we show that the proposed analytical model works well with the parameters of IEEE 802.11a and the difference in throughput between theoretical analysis and computer simulation is at most 2 percent.