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      • Query Subtopic Mining by Combining Multiple Semantics

        Lizhen Liu,Wenbin Xu,Wei Song,HanshiWang,Chao Du 보안공학연구지원센터 2015 International Journal of Multimedia and Ubiquitous Vol.10 No.12

        Query subtopic mining aims to find aspects to represent people’s potential intents for a query. Clustering query reformulations is the most common approach for subtopic mining these days. However, there are some challenges that the existing approaches have to face in finding both relevant and diverse subtopics, such as term mismatch and data sparseness. In this paper, a novel semantic representations for query subtopics is introduced, which including phrase embedding representation and query category distributional representation, to solve those problems mentioned above. Furthermore, we also combine multiple semantic representations into vector space model and compute a joint similarity for clustering query reformulations. To evaluate our theory an experiment is conducted on a public dataset offered by NTCIR subtopic mining project, the experimental results show that phrase embedding representation is the most effective representation while combining multiple semantics benefits short text clustering and improves the performance of query subtopic mining.

      • KCI등재

        Identification and Validation of Circulating MicroRNA Signatures for Breast Cancer Early Detection Based on Large Scale Tissue-Derived Data

        Xiaokang Yu,Jinsheng Liang,Jiarui Xu,Xingsong Li,Shan Xing,Huilan Liu,Wan-Li Liu,Dongdong Liu,Jianhua Xu,Lizhen Huang,Hongli Du 한국유방암학회 2018 Journal of breast cancer Vol.21 No.4

        Purpose: Breast cancer is the most commonly occurring cancer among women worldwide, and therefore, improved approaches for its early detection are urgently needed. As microRNAs (miRNAs) are increasingly recognized as critical regulators in tumorigenesis and possess excellent stability in plasma, this study focused on using miRNAs to develop a method for identifying noninvasive biomarkers. Methods: To discover critical candidates, differential expression analysis was performed on tissue-originated miRNA profiles of 409 early breast cancer patients and 87 healthy controls from The Cancer Genome Atlas database. We selected candidates from the differentially expressed miRNAs and then evaluated every possible molecular signature formed by the candidates. The best signature was validated in independent serum samples from 113 early breast cancer patients and 47 healthy controls using reverse transcription quantitative real-time polymerase chain reaction. Results: The miRNA candidates in our method were revealed to be associated with breast cancer according to previous studies and showed potential as useful biomarkers. When validated in independent serum samples, the area under curve of the final miRNA signature (miR-21-3p, miR-21-5p, and miR-99a-5p) was 0.895. Diagnostic sensitivity and specificity were 97.9% and 73.5%, respectively. Conclusion: The present study established a novel and effective method to identify biomarkers for early breast cancer. And the method, is also suitable for other cancer types. Furthermore, a combination of three miRNAs was identified as a prospective biomarker for breast cancer early detection.

      • SCIESCOPUSKCI등재

        Simulations for the cesium dynamics of the RF-driven prototype ion source for CRAFT N-NBI

        Yalong Yang,Yong Wu,Lizhen Liang,Jianglong Wei,Rui Zhang,Yahong Xie,Wei Liu,Chundong Hu Korean Nuclear Society 2024 Nuclear Engineering and Technology Vol.56 No.4

        To realize an initial objective of the negative ion-based neutral beam injection (N-NBI) at the Comprehensive Research Facility for Fusion Technology (CRAFT) test facility, which targets an H<sup>0</sup> beam power of 2 MW at an energy of 200-400 keV and a pulse duration of 100 s, it is crucial to study the cesium dynamics of the negative ion source. Here a numerical simulation program CSFC3D is developed and applied to simulate the distribution and time dynamics of cesium during short pulses. The calculations show that most of the cesium on the plasma grid (PG) area originates from the release of cesium that is accumulated within the ion source in the plasma phase. Increasing the wall temperature reduces the loss of cesium on the wall of the ion source. Furthermore, the thickness of the cesium monolayer is directly influenced by the PG temperature. Both simulated and experimental results demonstrate that maintaining the PG temperature between 180 ℃ and 200 ℃ is essential for enhancing the performance of the ion source and optimizing the cesium behavior.

      • KCI등재

        Joint Lattice-Reduction-Aided Precoder Design for Multiuser MIMO Relay System

        ( Hua Jiang ),( Hao Cheng ),( Lizhen Shen ),( Guoqing Liu ) 한국인터넷정보학회 2016 KSII Transactions on Internet and Information Syst Vol.10 No.7

        Lattice reduction (LR) has been used widely in conventional multiple-input multiple-output (MIMO) systems to enhance the performance. However, LR is hard to be applied to the relay systems which are important but more complicated in the wireless communication theory. This paper introduces a new viewpoint for utilizing LR in multiuser MIMO relay systems. The vector precoding (VP) is designed along with zero force (ZF) criterion and minimum mean square error (MMSE) criterion and enhanced by LR algorithm. This implementable precoder design combines nonlinear processing at the base station (BS) and linear processing at the relay. This precoder is capable of avoiding multiuser interference (MUI) at the mobile stations (MSs) and achieving excellent performance. Moreover, it is shown that the amount of feedback information is much less than that of the singular value decomposition (SVD) design. Simulation results show that the proposed scheme using the complex version of the Lenstra--Lenstra--Lovasz (LLL) algorithm significantly improves system performance.

      • KCI등재

        Study on the Flexural Fatigue Performance of CFRP-OFBG Plate Reinforced Damaged Steel Beams

        Langni Deng,Mengjun Zhong,Yang Liu,Ling Liao,Shijin Lai,Lizhen Lei,Zheng Zhou 대한토목학회 2021 KSCE Journal of Civil Engineering Vol.25 No.12

        This paper studies the flexural fatigue performance of damaged steel beams strengthened by carbon fiber reinforced plastic-optical fiber bragg grating (CFRP-OFBG) plates. By analyzing the test beam's failure mechanism under cyclic loading and the strain data monitored by the CFRP-OFBG panel in real-time, a life prediction model based on cumulative fatigue damage is proposed. The test results show that CFRP-OFBG plate reinforcement effectively reduces the fatigue crack growth rate of damaged steel beams and increases the fatigue life of damaged steel beams by 22.46%. The analysis and test results show that the minimum error between the calculated value of the life prediction model and the test value is -24.13%, and the maximum error is -5.61%. This study provides some suggestions for improving the service life of existing fatigue-damaged steel beams and establishing a simple fatigue life evaluation model.

      • KCI등재

        Synthesis and Magnetic Properties of FeCo Alloy Nanowires via AC Frequency Conversion Electrodeposition

        Lirong Wang,Shunzhen Feng,Tingting Lu,Lizhen Zhen,Jiwei Zhang,Lihu Liu 한국자기학회 2022 Journal of Magnetics Vol.27 No.3

        Binary alloy nanowires of Fe3Co7 system are synthesized in the highly ordered porous anodic aluminum oxide (PAA) templates by AC frequency (5, 50, 120, and 200 Hz) conversion electrodeposition method. High resolution field emission transmission electron microscope (HRTEM) and Lorenz TEM (LTEM) were used to study the morphology and the magnetic domain structure of the Fe3Co7 alloy nanowires, respectively. Magnetic measurements showed that the M-H curves presented a discontinuity in a restricted magnetic field, but with high squareness (about 90 %). Quantitative local measurements of the magnetic properties of the nanowires are explored by differential phase contrast (DPC) imaging. The magnetic properties, however, were significantly affected by the AC frequency, which is correlated with the specific magnetic structure formation of Bloch line. We reported herein a detailed investigation on Fe3Co7 alloy nanowires and their magnetic properties.

      • KCI등재

        Effect of Various Retrogression Regimes on Aging Behavior and Precipitates Characterization of a High Zn-Containing Al–Zn–Mg–Cu Alloy

        Kai Wen,Baiqing Xiong,Yongan Zhang,Zhihui Li,Xiwu Li,Shuhui Huang,Lizhen Yan,Hongwei Yan,Hongwei Liu 대한금속·재료학회 2018 METALS AND MATERIALS International Vol.24 No.3

        In the present work, the infl uence of various retrogression treatments on hardness, electrical conductivity and mechanicalproperties of a high Zn-containing Al–Zn–Mg–Cu alloy is investigated and several retrogression regimes subjected to a samestrength level are proposed. The precipitates are qualitatively investigated by means of transmission electron microscopy(TEM) and high-resolution transmission electron microscopy techniques. Based on the matrix precipitate observations, thedistributions of precipitate size and nearest inter-precipitate distance are extracted from bright-fi eld TEM images projectedalong ⟨110⟩ Al orientation with the aid of an imaging analysis and an arithmetic method. The results show that GP zonesand η′ precipitates are the major precipitates and the precipitate size and its distribution range continuously enlarge with theretrogression regime expands to an extent of high temperature. The nearest inter-precipitate distance ranges obtained arequite the same and the average distance of nearest inter-precipitates show a slight increase. The infl uence of precipitates onmechanical properties is discussed through the interaction relationship between precipitates and dislocations.

      • KCI등재

        Measurement and Theoretical Calculation Confirm the Improvement of T7651 Aging State Influenced Precipitation Characteristics on Fatigue Crack Propagation Resistance in an Al–Zn–Mg–Cu Alloy

        Kai Wen,Baiqing Xiong,Yongan Zhang,Zhihui Li,Xiwu Li,Lizhen Yan,Hongwei Yan,Hongwei Liu 대한금속·재료학회 2021 METALS AND MATERIALS International Vol.27 No.5

        Precipitation characteristics influencing fatigue crack propagation contained matrix precipitate, grain boundary precipitateand precipitate free zone for Al–Zn–Mg–Cu alloys. Over-aging treatment could effectively regulate precipitation and then tobe able to change fatigue crack propagation behavior compared with the peak aging state. In the current work, typical T651and T7651 aging tempers of the alloy were extracted via hardness, electrical conductivity and mechanical properties underone-step and two-step aging treatments. Fatigue crack propagation (FCP) rate under them was tested and correspondingprecipitation characteristics and fracture morphology were observed. The results indicated that fatigue crack propagationresistance for the T7651 temper possessed an obvious improvement on the side of that for the T651 temper, which was alsosupported by fracture appearance, including tearing ridge, tearing dimple and fatigue striation. The precipitation observationshowed that the T651 alloy contained GPI zone, GPII zone and ηʹ phase while the T7651 alloy possessed ηʹ phase and η phase.Compared with the T651 temper, matrix precipitate for the T7651 temper distinctly owed an expanding of size distributionand an enlargement of average size while cuttable phase still remained the dominance for both tempers. Grain boundaryprecipitate and precipitate free zone manifested no obvious difference between the two aging tempers. Cut and bypass mechanismsof dislocation–precipitate interactions were used for explanation and it revealed the reinforced cuttable phase was infavor of enhancing fatigue crack propagation resistance. A theoretical model which directly correlated FCP rate with matrixprecipitate characteristics was employed to calculate FCP rate by substituting quantitative precipitate characteristics and thecalculation results were vaguely consistent with the experimental measurement, which proved its reliability and feasibility.

      • KCI등재

        Characteristic and role of chromosomal type II toxin-antitoxin systems locus in Enterococcus faecalis ATCC29212

        Li Zhen,Shi Chao,Gao Shanjun,Zhang Xiulei,Lu Di,Liu Guangzhi 한국미생물학회 2020 The journal of microbiology Vol.58 No.12

        The Gram-positive bacterium Enterococcus faecalis is currently one of the major pathogens of nosocomial infections. The lifestyle of E. faecalis relies primarily on its remarkable capacity to face and survive in harsh environmental conditions. Toxin-antitoxin (TA) systems have been linked to the growth control of bacteria in response to adverse environments but have rarely been reported in Enterococcus. Three functional type II TA systems were identified among the 10 putative TA systems encoded by E. faecalis ATCC29212. These toxin genes have conserved domains homologous to MazF (DR75_ 1948) and ImmA/IrrE family metallo-endopeptidases (DR75_ 1673 and DR75_2160). Overexpression of toxin genes could inhibit the growth of Escherichia coli. However, the toxin DR75_1673 could not inhibit bacterial growth, and the bacteriostatic effect occurred only when it was coexpressed with the antitoxin DR75_1672. DR75_1948–DR75_1949 and DR75_ 160–DR75_2161 could maintain the stable inheritance of the unstable plasmid pLMO12102 in E. coli. Moreover, the transcription levels of these TAs showed significant differences when cultivated under normal conditions and with different temperatures, antibiotics, anaerobic agents and H2O2. When DR75_2161 was knocked out, the growth of the mutant strain at high temperature and oxidative stress was limited. The experimental characterization of these TAs loci might be helpful to investigate the key roles of type II TA systems in the physiology and environmental stress responses of Enterococcus.

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