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      • KCI등재

        Transcriptome reveals genes involving in black skin color formation of ducks

        Lei Wang,Hehe Liu,Bo Hu,Jiwei Hu,Hengyong Xu,Hua He,Chunchun Han,Bo Kang,Lili Bai,Rongping Zhang,Jiwen Wang,Shengqiang Hu,Liang Li 한국유전학회 2021 Genes & Genomics Vol.43 No.2

        Background Skin color is colorful for birds, which has been reported to be associated with multi-biological functions, such as crypsis, camoufage, social signaling and mate choice, but little is known about its underlying molecular mechanism. Objective Studies on the major genes afecting the black skin color of ducks. Methods For this purpose, Silver ammonia staining and RNA-seq analysis were carried out to identify the diferences in tissue morphology and gene expressions between black and yellow skin ducks. Results The silver ammonia dyes slice results showed that in the development of black duck, the content of melanin in black skin gradually increased and then decreased, and the content of melanin in yellow and black skin was signifcantly diferent. Through transcriptome, a total of 102 and 84 diferentially expressed genes (DEGs) were identifed in beak skin and web skin, respectively. These DEGs were enriched in melanin biosynthesis and play a critical role in melanogenesis pathway. Co-expression analysis showed that EDNRB2 was the only gene associated with black skin color in DEGs, which was also consistent with qRT-PCR. Conclusions The melanin synthesis pathway dominated by EDNRB2 up-regulated the amount of melanin synthesis, leading to the formation of black skin in ducks.

      • KCI등재

        Radiation Force Calculation and Acoustic Power Measurement for a Cylindrical Concave Transducer Based on the Ray Acoustic Model

        Lili Yu,Wende Shou,Chun Hui,Bing Hu 한국물리학회 2012 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.61 No.4

        New relationships between the radiation force and the acoustic power for a cylindrical concave transducer were derived based on the ray acoustic model. The performance of this model is compared with that of the far-field integration model. The numerical results showed excellent agreement. Thus, these two models can be applied in the correction of measured results. Moreover, the formula based on the ray acoustic model can be applied more widely in practice because of its simplicity. The experimental results demonstrated further the reliability of the relationships between the radiation force and the acoustic power in theory, and the feasibility of using cylindrical concave transducers based on the ray acoustic model in practice.

      • KCI등재
      • KCI등재

        Procedure for Ranking Ground Motion Records Based on the Destructive Capacity Parameter

        Jinjun Hu,Qinghui Lai,Shuang Li,Lili Xie 대한토목학회 2021 KSCE Journal of Civil Engineering Vol.25 No.1

        The relative input energy of a ground motion is used to quantitatively estimate the destructive capacity of ground motion to a structure, which reflects the deformation capacity and energy dissipation capacity of a structure. The destructive capacity of a ground motion on a structure is known to be relevant to the structural period. Because ranking the destructive capacity of ground motion at all periods is not practical, rationally dividing period ranges should be performed before ranking ground motions according to their destructive capacity and a new method to divide period ranges based on the relative input energy is proposed. According to the correlation coefficient of the relative input energy at adjacent structural periods, the structural periods from 0.2 s to 10 s are divided into several representational period ranges, which include a recommended period within each period range to represent the whole range. Only the ground motion ranking sequence at the recommended period is used in this period range. The rationality of the ranking sequence of ground motions based on destructive capacity is verified by a series of structural seismic response analyses. The results of this paper are compared with those of existing methods, and the results show that the relative input energy index is able to better quantitatively describe the destructive capacity of ground motion.

      • KCI등재

        Improving Patients’ Adherence to Physical Activity in Diabetes Mellitus: A Review

        Shan-hu Qiu,Zi-lin Sun,Xue Cai,Lili Liu,Bingquan Yang 대한당뇨병학회 2012 Diabetes and Metabolism Journal Vol.36 No.1

        Regular physical activity (PA) is a key element in the prevention and management of type 2 diabetes mellitus (T2DM). Participation in regular PA improves blood glucose control and can prevent or delay T2DM and its complications, along with positively affecting lipids, blood pressure, cardiovascular events, mortality, and quality of life. However, most people with T2DM are not active and show poor adherence. This paper reviews the possible barriers to PA and strategies to improve the adherence to PA. Based on the currently available literature, it is concluded that self-efficacy and social support from family, friends, and health care providers play the important role in adoption and maintenance of regular PA. Here we also highlight some new modern and innovative interventions that facilitate exercise participation and improve the adherence.

      • KCI등재

        Direct Electrochemistry and Electrocatalysis of Myoglobin with CoMoO4 Nanorods Modified Carbon Ionic Liquid Electrode

        Zengying Zhao,Lili Cao,Anhui Hu,Weili Zhang,Xiaomei Ju,Yuanyuan Zhang,Wei Sun 대한화학회 2013 Bulletin of the Korean Chemical Society Vol.34 No.2

        By using ionic liquid 1-hexylpyridinium hexafluorophosphate (HPPF6) based carbon ionic liquid electrode (CILE) as the substrate electrode, a CoMoO4 nanorods and myoglobin (Mb) composite was casted on the surface of CILE with chitosan (CTS) as the film forming material to obtain the modified electrode (CTS/ CoMoO4-Mb/CILE). Spectroscopic results indicated that Mb retained its native structures without any conformational changes after mixed with CoMoO4 nanorods and CTS. Electrochemical behaviors of Mb on the electrode were carefully investigated by cyclic voltammetry with a pair of well-defined redox peaks from the heme Fe(III)/Fe(II) redox center of Mb appeared, which indicated that direct electron transfer between Mb and CILE was realized. Electrochemical parameters such as the electron transfer number (n), charge transfer coefficient (α) and electron transfer rate constant (ks) were estimated by cyclic voltammetry with the results as 1.09, 0.53 and 1.16 s−1, respectively. The Mb modified electrode showed good electrocatalytic ability toward the reduction of trichloroacetic acid in the concentration range from 0.1 to 32.0 mmol L−1 with the detection limit as 0.036 mmol L−1 (3σ), and the reduction of H2O2 in the concentration range from 0.12 to 397.0 μmol L− 1 with the detection limit as 0.0426 μmol L−1 (3σ).

      • KCI등재

        Use of antibiotics and other treatments in Chinese adults with acute cough: An online survey

        Xiao-yang Hu,Ru-yu Xia,Michael Moore,Beth Stuart,Wen Ling-Zi,Bertrand Graz,Lai Lily,Liu Jian-Ping,Yu-tong Fei,Merlin Willcox 한국한의학연구원 2023 Integrative Medicine Research Vol.12 No.1

        Background: Acute respiratory tract infections are common worldwide and there has been a rapid in- crease in antibiotic consumption. This study aimed to identify use of various treatments and their as- sociation with the use of antibiotics and patient reported clinical recovery in Chinese adults with acute cough. Methods: An online survey recruiting people who had recently experienced cough was conducted. Their sociodemographic, clinical characteristics, treatments received and their perceived changes in symptoms were collected. Factors influencing avoidance of antibiotics and improvement in symptoms were explored. Results: A total of 22,787 adults with recent acute cough completed the questionnaire, covering all 34 province-level administrative units in China. Most respondents were male (68.0%), young (89.4%, aged 18–45), educated to university/degree or postgraduate level (44.6%), with a median cough severity of 6/10 on a numerical rating scale. Nearly half of the participants (46.4%) reported using antibiotics, among which 93.1% were for presumed upper respiratory tract infections (URTIs). Pharmacies (48.8%) were the most common source of antibiotics. Fewer patients took antibiotics after taking CHM (14.9%), compared to those who started with home remedies (18.0%), or allopathic non-antibiotic medication (25.0%). An- tibiotics, allopathic non-antibiotic medications, CHM and home remedies were all perceived beneficial in relieving cough. Conclusions: Chinese adult responders report use of a considerable variety of treatments alone or in combination for acute cough. Patient-reported clinical recovery was similar regardless of treatment. There is likely a high proportion of inappropriate use of antibiotics for treatment of simple acute cough. As the majority of respondents did not use antibiotics as a first-line, and use of CHM was associated with relief of cough symptoms and reduction in the use of antibiotics, this presents an important opportunity for prudent antibiotic stewardship in China.

      • KCI등재

        Effects of Glucagon-Like Peptide-2-Expressing Saccharomyces cerevisiae Not Different from Empty Vector

        ( Xi Zhong ),( Guopeng Liang ),( Lili Cao ),( Qi Qiao ),( Zhi Hu ),( Min Fu ),( Hong Bo ),( Qin Wu ),( Guanlin Liang ),( Zhongwei Zhang ),( Lin Zhou ) 한국미생물생명공학회(구 한국산업미생물학회) 2019 Journal of microbiology and biotechnology Vol.29 No.10

        Saccharomyces cerevisiae (S. cerevisiae) and glucagon-like peptide-2 (GLP-2) have been employed to improve the intestinal development of weaned animals. The goal of this study was to determine whether either exogenous S. cerevisiae or GLP-2 elicits major effects on fecal microbiotas and cytokine responses in weaned piglets. Ninety-six piglets weaned at 26 days were assigned to one of four groups: 1) Basal diet (Control), 2) empty vector-harboring S. cerevisiae (EV-SC), 3) GLP-2-expressing S. cerevisiae (GLP2-SC), and 4) recombinant human GLP-2 (rh-GLP2). At the start of the post-weaning period (day 0), and at day 28, fecal samples were collected to assess the bacterial communities via sequencing the V1-V2 region of the 16SrRNA gene, and piglets’ blood was also sampled to measure cytokine responses (i.e., IL-1β, TNF-α, and IFN-γ). This study revealed that, on the one hand, although S. cerevisiae supplementation did not significantly alter the growth of weaned piglets, it induced increases in the relative abundances of two core genera (Ruminococcaceae_norank and Erysipelotrichaceae_norank) and decreases in the relative abundances of two other core genera (Lachnospiraceae_norank and Clostridiale_norank) and cytokine levels (IL-1β and TNF-α) (p < 0.05, Control vs EV-SC; p < 0.05, rh-GLP2 vs GLP2-SC). On the other hand, GLP-2 supplementation had no significant influence on fecal bacterial communities and cytokine levels, but it produced better body weight and average daily gain (p < 0.05, Control vs EV-SC; p < 0.05, rh-GLP2 vs GLP2-SC). Therefore, altered fecal microbiotas and cytokine response effects in weaned piglets were due to S. cerevisiae rather than GLP-2.

      • KCI등재

        Enhanced photocatalytic activity of TiO2/graphene by tailoring oxidation degrees of graphene oxide for gaseous mercury removal

        Yu Guan,Tao Hu,Jiang Wu,Lili Zhao,Fengguo Tian,Wei-Guo Pan,Ping He,Xuemei Qi,Fangqin Li,Kai Xu 한국화학공학회 2019 Korean Journal of Chemical Engineering Vol.36 No.1

        We used a simple method of graphene oxide (GO) preparation with different oxidation levels, and control the properties of the TiO2 nanocrystals by tuning the content and oxidation degree of GO to enhance the photocatalytic performance. During the hydrothermal reaction, reduction of GO, formation of TiO2 and chemical bonds between TiO2 and reduced graphene oxide (RGO) was achieved simultaneously. Characterization results showed that TiO2 properties such as crystalline grain and particle size could be tailored by the amount of functional groups, and that crystallinity was also controlled by GO degrees of oxidation. TiO2/RGO photocatalysts showed great efficiency of mercury oxidation, which reached 83.7% and 43.6% under UV and LED light irradiation, respectively. The effects of crystalline grain size and surface chemical properties on Hg0 removal under LED and UV light irradiation were analyzed. In addition, the properties of the photocatalysts before and after UV illumination were investigated, finding that part of Ti-OH on TiO2 surface transformed to Ti-O-Ti. In a nutshell, this work could provide a new insight into enhancing activity of photocatalysts and understanding the photocatalytic mechanism.

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