Effect of Anhydride Grafting Agent on Trap Levels of Low-Density Polyethylene

Lijuan He,Zhenhua Yuan,Xiong Yang,Huiqing Niu,Chao Zhu,Dawei Li,Lei Zhao,Chuntian Chen 보안공학연구지원센터 2016 International Journal of Security and Its Applicat Vol.10 No.5

Trap distribution of the low-density polyethylene(LDPE) modified by anhydride grafting agent was studied and the effect of grafting agent on the trap levels was analyzed by the method of Photo-stimulated Discharge in this paper. Different concentrations and types of same concentration of LDPE modified by anhydride grafting agent were measured by using continuous UV scanning. The results showed that different concentrations and types of grafting agent had effect on trap levels distribution of LDPE. The trap depth would decrease with the anhydride grafting agent content increasing and increase with its damaged condition increasing when anhydride grafting agent was destroyed. Anhydride grafting agent are widely applied to the production and research of high pressure insulating polyethylene materials. The purpose of this paper is to elaborate the effect of anhydride grafting agent on the insulating properties of polyethylene material and explain the strongest binding capacity of anhydride grafting agent to space charge.

A novel multiemissive Ln/covalent-organic frameworks for ratiometric detection of 2,6-dipicolinic acid

Lijuan Kuang,Yue Du,Shiqi Wang,Li Yang,Yonghai Song 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.106 No.-

As one of the specific biomarkers of anthrax, timely, sensitive and accurate detection of 2,6-dipicolinicacid (DPA) plays an important role in preventing biological weapons attacks and disease outbreaks. Here, multiemission Eu3+/covalent- organic framework (COFDTA-TFP) and Tb3+/COFDTA-TFP were constructedby the coordination between Eu3+ or Tb3+ with fluorescent COFDTA-TFP which was prepared byamine-aldehyde dehydration condensation between 2,5-diaminoterephthalic acid and 2,4,6-triformylphloroglucinol for the first time. The Eu3+/COFDTA-TFP and Tb3+/COFDTA-TFP can emit nonoverlappingfluorescence of COFDTA-TFP and Eu3+ or Tb3+, which was used to ratiometric detection ofDPA. Due to the strong coordination between the nitrogen atoms in the pyridine ring and the oxygenatoms in the carboxyl group of DPA with Eu3+ or Tb3+, DPA replaced coordinated H2O to sensitize fluorescenceof Eu3+ or Tb3+ by ‘‘antenna” effect but fluorescence of COFDTA-TFP with two-dimensional lamellarstructure was kept constant as a reference. The linear range and detection limit of ratiometric fluorescencesensor based on Eu3+/COFDTA-TFP for detection of DPA are 0.01–12 mM and 4.2 nM, respectively. The linear range and detection limit of ratiometric fluorescence sensor based on Tb3+/COFDTA-TFP fordetection of DPA are 0.01–9.0 mM and 2.9 nM, respectively.

A Ultra-Low Specific On-Resistance and Extended Gate SJ LDMOS Structure

Lijuan Wu,Jiaqi Chen,Hang Yang,QiLin Ding,Xing Chen,Shaolian Su 한국전기전자재료학회 2021 Transactions on Electrical and Electronic Material Vol.22 No.3

A new structure of extended gate (EG) SJ LDMOS is proposed in this paper to overcome the substrate assisted depletion (SAD) eff ect in the structure of Super-Junction lateral double diff used metal oxide semiconductor (SJ LDMOS). Different from other surface SJ structures, the SJ layer of the structure is located in the body of the drift region. Gate oxide and silicon layer form the EG Structure-Oxide-Semiconductor structure that is similar to Metal–Insulator–Semiconductor capacitor. The the N-drift of the EG structure can obtain the charge compensation to overcome the SAD eff ect, and a nearly rectangular electric field is achieved. In the on-state, the EG structure has two conductive channels and the accumulation layer is formed on the drift region. By accumulating high concentration electrons in the channels, the specifi con-resistance ( R ON,sp ) is greatly reduced. When the drift length is 24 μm, 431.4 V breakdown voltage ( V B ) and 9.8 mΩ cm 2 R ON,sp are achieved, and the fi gure of merit is 18.9 MW cm −2 .

Finite-time Incremental Stability Analysis for Nonlinear Switched Systems With Unstable Subsystems

Lijuan Wang,Yuanhong Ren,Yushi Yang,Lin Guan 제어·로봇·시스템학회 2023 International Journal of Control, Automation, and Vol.21 No.10

In this paper, finite-time incremental stability (FTIS) and finite-time incremental boundedness (FTIB) are investigated for nonlinear switched systems (NSS) with unstable systems. Firstly, based on the reverse modedependent average dwell time (MDADT) method, we propose some sufficient conditions for FTIS of NSS. Secondly, the sufficient conditions for NSS to be FTIB with an incremental performance index are given by the multiple incremental Lyapunov functions. Finally, a distinctive advantage of reverse MDADT method is that each subsystems satisfies FTIB in the activation interval. A example has been provided to show the effectiveness of the theoretic results developed.

Characterization of a Thermophilic Hemoglobin-degrading Protease from Streptomyces rutgersensis SCSIO 11720 and Its Application in Antibacterial Peptides Production

Jian Yang,Jie Li,Yunfeng Hu,Lizhen Li,Lijuan Long,Fazuo Wang,Si Zhang 한국생물공학회 2015 Biotechnology and Bioprocess Engineering Vol.20 No.1

High value utilization of byproduct of slaughterhousesis regarded as beneficial to both economy andenvironment. A hemoglobin degrading protease PA720was purified from fermentation broth of a Porites luteaassociated strain Streptomyces rutgersensis SCSIO 11720(SCSIO 11720) and exhibited maximal activity at 70°C,pH 10.5. The isolated strain was identified by genotypicmethod and 16 s RNA gene sequence was deposited inGenBank under accession No. KC414842. The enzymeexhibited excellent thermostability since it was stable at 70°Cwith t1/2 value of 1,386.3 min. Kinetic and thermodynamicstudy showed the activation energy (Ea), ΔG* (free energy),ΔH* (enthalpy) and ΔS* (entropy) for protease deactivationwere 62.71 kJ/mol, 74.26 kJ/mol, 59.86 kJ/mol, and-41.97 J/mol/K, respectively. Highest specific activity ofprotease PA720 was observed when using casein (9,953 U/mg)and hemoglobin (9,854 U/mg) as substrates. Hemoglobinhydrolysate prepared by protease PA720 showed significantantibacterial activity towards Escherichia coli, Staphylococcusaureus and Bacillus subtilis, indicating this protease couldbe used as an instrumental enzyme for production ofhemoglobin-based antibacterial peptides. Based on partialamino acid sequences of the enzyme PA720, the full geneencoding this protease was obtained by degenerate primerPCR and has been deposited in GenBank under accessionNo. KC414842. The deduced amino acid sequence exhibitshomology with other microbial thermophilic proteases insubtilisin family.

Expression and localization of insulin-like growth factor-I in four parts of the red deer antler

Gu, Lijuan,Mo, Eunkyoung,Yang, Zhihong,Zhu, Xuemei,Fang, Zheming,Sun, Baishen,Wang, Chunyan,Bao, Jianfeng,Sung, Changkeun Informa Healthcare 2007 Growth factors Vol.25 No.4

<P> The expression and localization of insulin-like growth factor-I (IGF-I) in the four parts (tip, upper, mid and base) of the red deer antler has been extensively investigated. We used reverse transcriptase polymerase chain reaction (RT-PCR) and real-time reverse transcriptase polymerase chain reaction (real time RT-PCR), in situ hybridization, immunohistochemistry and Western blot techniques to localize IGF-I messenger ribonucleic acid (mRNA) and IGF-I peptide in the four parts of the antler. The specific sequence encoding IGF-I was detected by RT-PCR in all of the four specimens, and the 395 bp IGF-I sequence from the red deer antler was shown to have very high homology with human, goat and mouse IGF-I. In situ hybridization and immunohistochemistry results demonstrated that the expression of IGF-I occurred in chondrocytes and osteoblasts in the tip and upper parts of the antler. However, IGF-I was only detectable in osteoblasts around the bone in the mid and base parts. There were significant differences in the intensity of the signal obtained with the IGF-I probe in the tip, upper, mid and base tissues. The Western blot analysis also provided evidence that IGF-I expression was localized differentially in the four parts of the deer antler. This study indicates that antler tissue is an essential part of the IGF system, which is involved in the regulation of the growth of red deer antlers. The specific expression of IGF-I in the four parts of the deer antler suggests that the IGF-I molecule is present at significantly different levels throughout the deer antler development and regeneration processes. Localization of IGF-I in chondrocytes and osteoblasts suggests that IGF-I may play an important role in cartilage and bone formation. In addition, it may have a variety of biophysical effects that influence the rapid growth of deer antlers.</P>

Effects of Red Deer Antlers on Cutaneous Wound Healing in Full-thickness Rat Models

Gu, LiJuan,Mo, EunKyoung,Yang, ZhiHong,Fang, ZheMing,Sun, BaiShen,Wang, ChunYan,Zhu, XueMei,Bao, JianFeng,Sung, ChangKeun Asian Australasian Association of Animal Productio 2008 Animal Bioscience Vol.21 No.2

The process of wound repair involves an ordered sequence of events such as overlapping biochemical and cellular events that, in the best of circumstances, result in the restoration of both the structural and functional integrity of the damaged tissue. An important event during wound healing is the contraction of newly formed connective tissues by fibroblasts. The polypeptide growth factors, like transforming growth factor-${\beta}$(TGF-${\beta}$, insulin-like growth factor I (IGF- I) and epidermal growth factor (EGF), play very important mediator roles in the process of wound contraction. Deer antlers, as models of mammalian regeneration, are cranial appendages that develop after birth as extensions of a permanent protuberance (pedicle) on the frontal bone. Antlers contain various growth factors which stimulate dermal fibroblast growth. They are involved in digestion and respiration and are necessary for normal wound healing and skin health. In order to investigate and evaluate the effects of red deer antlers on skin wound site, the speed of full-thickness skin wound healing and the expression of IGF-I, TGF-${\beta}$ and EGF in skin wounds, three groups of skin full-thickness rat models with a high concentration of antler ointment, a low concentration of antler ointment and without antler ointment were compared. At post-injury days 0, 2, 4, 8, 16, 20, 32, 40 and 60, the skin wound area was measured, the expressions of IGF-I, TGF- ${\beta}$ and EGF mRNA were detected by reverse transcriptase polymerase chain reaction (RT-PCR) and collagen formation by sirius red dye and the localization of IGF-I, TGF-${\beta}$ and EGF peptides were inspected by histological immunohistochemical techniques. Wound healing was significantly more rapid in antler treated skins. In addition, the wound treated with a high concentration antler ointment, a low concentration antler ointment, and the control closed completely at post-injury day 40, day 44 and day 60, respectively. Via RT-PCR, the expressions of IGF-I (day 8 and day 16), TGF-${\beta}$(day 8, day 16 and day 20) and EGF (day 4, day 8, day 16, and day 32) were obviously up-regulated in high concentration antler-treated skins compared to control skins. Similar results could be seen in the histological detection of collagen dye and immunohistochemical methods using the corresponding polyclone antibodies of IGF-I, TGF-${\beta}$ and EGF. These results illustrate that antlers stimulate and accelerate the repair of cutaneous wounds.

Study on the grading standard of Panax notoginseng seedlings

Chen, Lijuan,Yang, Ye,Ge, Jin,Cui, Xiuming,Xiong, Yin The Korean Society of Ginseng 2018 Journal of Ginseng Research Vol.42 No.2

Background: The quality differences in seedlings of medicinal herbs often affect the quality of medicinal parts. The establishment of the grading standard of Panax notoginseng seedlings is significant for the stable quality of medicinal parts of P. notoginseng. Methods: To establish the grading standard of P. notoginseng seedlings, a total of 36,000 P. notoginseng seedlings were collected from 30 producing areas, of which the fresh weight, root length, root diameter, bud length, bud diameter, and rootlet number were measured. The K-means clustering method was applied to grade seedlings and establish the grading standard. Results: The fresh weight and rootlet number of P. notoginseng seedlings were determined as the final indices of grading. P. notoginseng seedlings from different regions of Yunnan could be preliminarily classified into four grades: the special grade, the premium grade, the standard grade, and culled seedlings. Conclusion: The grading standard was proven to be reasonable according to the agronomic characters, emergence rate, and photosynthetic efficiency of seedlings after transplantation, and the yields and contents of active constituents of the medicinal parts from different grades of seedlings.

Kidney Transplantation and Clinical Outcomes in Patients With Multiple Myeloma: Evidence From the United States Nationwide Inpatient Sample

Bo Yang,Lijuan Zhang,Xuechun Lu 대한배뇨장애요실금학회 2023 International Neurourology Journal Vol.27 No.3

Purpose: Patients with multiple myeloma (MM) are prone to developing persistent renal insufficiency. Novel therapeutic medications have improved long-term survival, making kidney transplantation (KT) a viable treatment option for MM survivors with end-stage renal disease. This study aimed to investigate the clinical outcomes in patients with MM who have received KT. Methods: Data from hospitalized patients ≥40 years of age with MM in the Nationwide Inpatient Sample 2016–2018 of the United States were queried. Patients were classified as having or not having undergone KT, as well as the stage of chronic kidney disease (CKD) for those who had not received KT. Propensity-score matching (PSM) was applied to balance the characteristics between the groups. Binary logistic regression was utilized to determine the associations between study variables and inhospital mortality, unfavorable discharges, prolonged length of stay (LOS), and major complications. Results: In total, 50,654 hospitalized patients with MM were identified, of whom 165 (0.3%) had received KT and 50,489 had not (5,905 at stage 5 CKD [CKD5D], 11,559 at stage 1–4 CKD [CKD1-4D], and 33,025 who were CKD-free). After PSM, between-group demographic and hospital-related characteristics were balanced. Binary regression analysis revealed that, compared to patients who were CKD-free, patients at CKD5D were significantly more likely to experience a prolonged LOS (odds ratio [OR], 1.31; 95% confidence interval [CI], 1.01–1.70) after adjusting for relevant confounders. Furthermore, compared to CKD-free patients, those who underwent KT were significantly more likely to have sepsis (OR, 1.48; 95% CI, 1.02–2.14). However, KT showed no association with the other adverse inpatient outcomes. Conclusions: Although KT is not common in MM patients, those who had undergone KT had comparable hospital outcomes to CKD-free patients. These data will help clinicians deliver better consultations to MM patients attempting to receive KT.

Effects of Lactobacillus curvatus and Leuconostoc mesenteroides on Suan Cai Fermentation in Northeast China^s

( Hongyan Yang ),( Hao Wu ),( Lijuan Gao ),( Hongbai Jia ),( Yuan Zhang ),( Zongjun Cui ),( Yuhua Li ) 한국미생물 · 생명공학회 2016 Journal of microbiology and biotechnology Vol.26 No.12

To investigate the effects of Lactobacillus curvatus and Leuconostoc mesenteroides on suan cai (pickled Chinese cabbage) fermentation, L. curvatus and/or Ln. mesenteroides were inoculated into suan cai. Physicochemical indexes were measured, and the microbial dynamics during the fermentation were analyzed by Illumina MiSeq sequencing and quantitative polymerase chain reaction (qPCR). The results showed that inoculation with lactic acid bacteria (LAB) lowered the pH of the fermentation system more rapidly. The decrease in water-soluble carbohydrates in the inoculated treatments occurred more rapidly than in the control. The LAB counts in the control were lower than in other inoculated treatments during the first 12 days of fermentation. According to the Illumina MiSeq sequencing analyses, Firmicutes, Proteobacteria, Bacteroidetes, Actinobacteria, Cyanobacteria, Fusobacteria, and Verrucomicrobia were present in the fermentations, along with other unclassified bacteria. Generally, Firmicutes was predominant during the fermentation in all treatments. At the genus level, 16 genera were detected. The relative abundance of Lactobacillus in all inoculated treatments was higher than in the control. The relative abundance of Lactobacillus in the treatments containing L. curvatus was higher than in the Ln. mesenteroides-only treatment. The relative abundance of Leuconostoc in the Ln. mesenteroides-containing treatments increased continuously throughout the fermentation. Leuconostoc was highest in the Ln. mesenteroides-only treatment. According to the qPCR results, L. curvatus and/or Ln. mesenteroides inoculations could effectively inhabit the fermentation system. L. curvatus dominated the fermentation in the inoculated treatments.