Look at a flower lamp

( Leon ) 한국무용연구학회 2020 한국무용연구회 국제학술발표논문집 Vol.2020 No.-

A Study on Rigid Foam / Evacuated Powder Composite Panels for Thermal Insulation

Leon R Glicksman(Leon R Glicksman),홍진관(Jin Kwan Hong) 대한설비공학회 1995 대한설비공학회 학술발표대회논문집 Vol.1995 No.11

Reflections on the Lack of Consideration of Ethnic Ancestry to Stratify Clozapine Dosing

Jose de Leon(Jose de Leon ) 대한신경정신의학회 2023 PSYCHIATRY INVESTIGATION Vol.20 No.3

This review article argues against trusting standard clozapine references, including the US package insert, because they do not include advances in the sciences of pharmacokinetics and pharmacovigilance and ignore the effects of ethnic ancestry on therapeutic dosing. The minimum therapeutic dose leading to the minimum therapeutic concentration of 350 ng/mL in serum/plasma can be used to compare individuals/groups with treatment-resistant schizophrenia. The US clozapine package insert recommends targeting doses of 300-450 mg/day and, subsequently, increments of up to 100 mg with a maximum dose of 900 mg/day. Ethnic ancestry is defined by DNA ancestry group. Asians (people with ancestry ranging from Pakistan to Japan) and Indigenous Americans are similar in clozapine dosing; their average clozapine minimum therapeutic dose ranged from 166 mg/day (female non-smokers) to 270 mg/day (male smokers). For those with European ancestry, average clozapine minimum therapeutic doses ranged from 236 mg/day (female non-smokers) to 368 mg/day (male smokers). Based on limited studies, Black (African sub-Saharan ancestry) patients may be treated with typical US doses (300-600 mg/day), assuming no poor metabolism (PM) status. Ancestry’s impact on clozapine lethality in four countries is discussed (two countries with highly homogenous populations, Denmark and Japan, and two countries with increasingly heterogenous populations due to immigration, Australia and the UK). An international guideline with 104 authors from 50 countries/regions was recently published, providing 6 personalized clozapine titration schedules for adult inpatients (3 ancestry groups and PM/non-PM schedules) and recommending c-reactive protein monitoring at baseline and weekly for 4 weeks.

Dr. Pablo Mendes de Leon Director, International Institute of Air and Space Law Leiden University, Leiden, The Netherlands

Pablo Mendes de Leon 숭실대학교 법학연구소 1998 法學論叢 Vol.11 No.-

North Korea’s Earthquake

Leon V. Sigal 동아시아재단 2013 Global Asia Vol.8 No.1

Morphometrics of Scinaia latifrons (Nemaliales, Rhodophyta) in the Southwestern Gulf of California, Mexico

Leon-Cisneros, Karla,Riosmena-Rodriguez, Rafael The Korean Society of Phycology 2005 ALGAE Vol.20 No.1

Scinaia latifrons Howe occurs in rhodolith beds between 9 to 27 m depths at San Lorenzo channel, Gulf of California, Mexico. As very little was known about the morphometrics of this normally temperate species in a subtropical area, we investigated the phenological changes from December 1998 to December 1999. The gametophytic phase of the species was present from late February to late May, which represented a shorter time period to other known species in the genus. Our results suggested that two gametophytic cohorts develop over winter and early spring based on the size class structure of the frond height. Thalli became reproductively mature at a small size (1-2 cm in height) and all the plants were monoecious. Scinaia latifrons at the study location underwent allometric growth, indicated by the lack of correlation between size, width of the plants, or branching patterns.

Situational Philosophy : Towards a theory of philosophical practice

( Leon De Haas ) 한국철학상담치료학회 2012 철학 실천과 상담 Vol.3 No.-

This essay is a revised and expanded version of the text which was the basis for the author’s Masterclass at the 11th International Conference on Philosophical Practice (ICPP), the 18th of July 2012 at the Humanities Institute, Kangwon National University in Chuncheon, Republic of Korea. The main goal of the essay is, to contribute to a theory of philosophical practice. To do this, the author develops a criticism of reductionist practices in philosophy. The theoretical point of departure is an abridged survey of the two paradigmatic changes in European philosophy in the 20th century, i.e., Husserl’s phenomenology, and Wittgenstein’s language game analysis. The line of thinking is illustrated by a case story of the author. Part I discusses the phenomenological and linguistic turns in European philosophy. Part II describes and discusses a case story. Part III criticizes two forms of reductionism in philosophical practice, namely psychological and conceptual reductionism. Part IV gives an initial impetus to a theory of philosophical practice beyond any reductionism. In the present essay, the author is dealing with Western philosophy only, as the origins of post-Modern philosophical practice are rooted in Western philosophy. Lately, Eastern philosophy has been an inspiration for philosophical practice as well.

Building a Peace Regime in Korea: An American View

Leon V. Sigal 통일연구원 2006 International journal of korean unification studie Vol.15 No.1

Mutual deterrence makes the risk of deliberate aggression on the Korean Peninsula quite low, but the very steps that both sides have taken to deter pre-meditated war have increased the risk of inadvertent war. For a peace treaty to be militarily meaningful, the force postures and war plans on both sides that pose an excessive risk of pre-emptive war have to be altered. That will require mutual and reciprocal, though not necessarily identical steps by both sides to defuse the volatile standoff at the DMZ. That is a demanding task, and one that is unlikely to succeed without fostering a conducive political environment first. One way to foster that environment is a series of peace agreements, as distinct from a peace treaty, that establishes a new three.way peace mechanism and develops some politically useful, though militarily less meaningful, confidencebuilding measures. Such peace agreements, in which the United States is a signatory, are a way to give the DPRK a form of diplomatic recognition, thereby facilitating a resolution of the current nuclear crisis. The September 19, 2006 joint statement gives impetus to this effort when it says “the directly related parties will negotiate a permanent peace regime on the Korean Peninsula at an appropriate separate forum.” Mutual deterrence makes the risk of deliberate aggression on the Korean Peninsula quite low, but the very steps that both sides have taken to deter pre-meditated war have increased the risk of inadvertent war. For a peace treaty to be militarily meaningful, the force postures and war plans on both sides that pose an excessive risk of pre-emptive war have to be altered. That will require mutual and reciprocal, though not necessarily identical steps by both sides to defuse the volatile standoff at the DMZ. That is a demanding task, and one that is unlikely to succeed without fostering a conducive political environment first. One way to foster that environment is a series of peace agreements, as distinct from a peace treaty, that establishes a new three.way peace mechanism and develops some politically useful, though militarily less meaningful, confidencebuilding measures. Such peace agreements, in which the United States is a signatory, are a way to give the DPRK a form of diplomatic recognition, thereby facilitating a resolution of the current nuclear crisis. The September 19, 2006 joint statement gives impetus to this effort when it says “the directly related parties will negotiate a permanent peace regime on the Korean Peninsula at an appropriate separate forum.”

NORTH KOREA POLICY ON THE ROCKS: WHAT CAN BE DONE TO RESTORE CONSTRUCTIVE ENGAGEMENT?

Leon V. Sigal 동아시아재단 2009 Global Asia Vol.4 No.2

Revenue Maximizing Scheduling for a Fast Electric Vehicle Charging Station with Solar PV and ESS

Leon, Nishimwe H.,Yoon, Sung-Guk Korea Electric Power Corporation 2020 KEPCO Journal on electric power and energy Vol.6 No.3

The modern transportation and mobility sector is expected to encounter high penetration of Electric Vehicles (EVs) because EVs contribute to reducing the harmful emissions from fossil fuel-powered vehicles. With the prospective growth of EVs, sufficient and convenient facilities for fast charging are crucial toward satisfying the EVs' quick charging demand during their trip. Therefore, the Fast Electric Vehicle Charging Stations (FECS) will be a similar role to gas stations. In this paper, we study a charging scheduling problem for the FECS with solar photovoltaic (PV) and an Energy Storage System (ESS). We formulate an optimization problem that minimizes the operational costs of FECS. There are two cost and one revenue terms that are buying cost from main grid power, ESS degradation cost, and revenue from the charging fee of the EVs. Simulation results show that the proposed scheduling algorithm reduces the daily operational cost by effectively using solar PV and ESS.