http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Enhanced UV stability of perovskite solar cells with a SrO interlayer
Lee, Sang-Won,Kim, Seongtak,Bae, Soohyun,Cho, Kyungjin,Chung, Taewon,Hwang, Jae-Keun,Song, Inseol,Lee, Wonkyu,Park, Sungeun,Jung, Jaebong,Chun, Jihun,Lee, Yoon Jung,Moon, Yeon Ji,Lee, Hae-Seok,Kim, Do Elsevier 2018 Organic Electronics Vol.63 No.-
<P><B>Abstract</B></P> <P>We investigated strontium oxide (SrO) as an interlayer material to enhance the UV stability of a CH<SUB>3</SUB>NH<SUB>3</SUB>PbI<SUB>3</SUB> perovskite solar cell. Moisture and over 400 nm wavelength of light were excluded to investigate the effect of UV light only. Two different interlayer fabrication processes were examined to optimize the performance of this solar cell. Devices fabricated by dipping for 30 min in SrO solution exhibited photoconversion efficiencies of 15.5%, whereas those fabricated with 60-min dipping showed photoconversion efficiencies of 15% and exhibited local Sr agglomeration. Devices with SrO displayed lower initial efficiencies than those without any SrO layer (17.6%), However, a device without SrO retained only 34.4% of its initial efficiency after 100 h of UV exposure. In contrast, SrO-incorporated devices retained almost 60.0% of their initial efficiency. Severe μ-PL mapping intensity degradation was observed in devices that did not include the interlayer, but no degradation was observed in those with the SrO interlayer. This can be attributed to the passivation of the degradation sites by SrO.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Perovskite UV stability was tested under conditions except moisture, oxygen and wavelengths exceeding 400 nm. </LI> <LI> With high resolution μ-PL mapping technique, direct evidence is provided about the area perovskite UV degradation begins. </LI> <LI> UV degradation is initiated at the ETL/perovskite interface. </LI> <LI> Effect of the SrO interlayer on UV stability was examined in an inert atmosphere. </LI> <LI> UV stability is enhanced by SrO interface passivation. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
Coenzyme Q10 Inhibits Th17 and STAT3 Signaling Pathways to Ameliorate Colitis in Mice
Lee, Seon-Yeong,Lee, Seung Hoon,Yang, Eun-Ji,Kim, Jae-Kyung,Kim, Eun-Kyung,Jung, KyungAh,Jung, Hongsoon,Lee, Kyungjin,Lee, Han Hee,Lee, Bo-In,Park, Sung-Hwan,Shin, Dong Yun,Cho, Mi-La Mary Ann Liebert, Inc. Publishers 2017 Journal of Medicinal Food Vol. No.
<P>Coenzyme Q10 (CoQ10) is a powerful antioxidant substance synthesized in the body. The current study aimed to determine whether CoQ10 suppresses inflammation and inhibits p-STAT3 expression in an experimental colitis mouse model. The mice were orally fed with CoQ10 once a day for 13 days. Histological analysis of the colons was performed by immunohistochemistry. Expression of IL-17, FOXP3, p53, AMPK, and mTOR and activation of p-STAT3 and p-STAT5 in lymph node and spleen tissues were detected by confocal microscopy of stained tissue sections. The relative mRNA expression was measured with real-time PCR, and protein levels were examined by western blot. CoQ10 reduced the disease activity index score and the colon histological score. It also reduced inflammatory mediators in the colon and increased the colon length. The expression of IL-17 and p-STAT3 was decreased with CoQ10 treatment. In contrast, CoQ10 treatment increased the expression of p-AMPK and FOXP3. Expression of anti-inflammatory cytokines was shown to increase in colitis mice treated with CoQ10. These results suggested that CoQ10 may reduce the severity of colitis and suppress inflammation through the inhibition of p-STAT3 and IL-17. These results support the use of CoQ10 as a potential targeted therapy for the treatment of colitis.</P>
Influence of hormone therapy on platinum-based chemotherapy using ovarian cancer cell line
( Kyungjin Lee ),( Minkyung Lee ),( Taehee Kim ),( Yejeong Kim ),( Sina Jang ),( Banghyun Lee ),( Sung Ook Hwang ) 대한산부인과학회 2022 대한산부인과학회 학술대회 Vol.108 No.-
Objective: In epithelial ovarian, primary peritoneal, or fallopian tube cancer (EOC), no studies have analyzed impacts of hormone therapy combined with platinum-based chemotherapy according to hormonal receptor expression. This study evaluated influence of hormone therapies (according to hormonal receptor expressions) and their molecular mechanisms on efficacy of platinum-based chemotherapy using a high-grade serous ovarian cancer (HGSC) cell line. Methods: Caov3 cells were stimulated with the following therapeutic agents: paclitaxel (P); carboplatin (C); tamoxifen (T); MPA (M); paclitaxel and tamoxifen (PT); paclitaxel and MPA (PM); carboplatin and tamoxifen (CT); carboplatin and MPA (CM); paclitaxel and carboplatin (PC); paclitaxel, carboplatin, and tamoxifen (PCT); and paclitaxel, carboplatin, and MPA (PCM). MTT assay was performed, and quantitative real-time RT-PCR and methylation assay using estrogen receptor (ER)-, ER-, progesterone receptor (PR)-A, PR-B, and PR-AB were performed. Results: Compared with the non-treated (NT) group, Caov3 cell viability decreased significantly in all groups with the highest decreases in the T and PCT groups (P <0.05). Viability increased significantly in PT and PM groups compared with P group, and in CM group compared with C group (P <0.05). Additionally, compared with PC group, viability decreased significantly in PCT group and increased significantly in PCM group (P <0.05). Expressions of ER-, ER-, and PR-B to PR-AB were not different between the groups. In methylation analyses of ER-, ER-, PR-A, and PR-B genes, methylation of promoters and gene bodies of PCT group were different from the other groups. Conclusion: Combinations of tamoxifen or MPA have influences on platinum-based chemotherapy efficacy in HGSC cells regardless of ER and PR expression. Methylation of ER and/or PR might have influences on HGSC cell proliferation under a combination of platinum-based chemotherapy and tamoxifen.
조경진(Kyungjin Cho),김성탁(Seongtak Kim),배수현(Soohyun Bae),정태원(Taewon Chung),이상원(Sang-won Lee),이경동(Kyung Dong Lee),이승훈(Seunghun Lee),권구한(Guhan Kwon),안세원(Seh-Won Ahn),이헌민(Heon-Min Lee),고민재(Min Jae Ko),강윤묵(Yo 한국태양광발전학회 2016 Current Photovoltaic Research Vol.4 No.2
The power conversion efficiency of perovskite solar cells has remarkably increased from 3.81% to 22.1% in the past 6 years. Perovskite solar cells, which are based on the perovskite crystal structure, are fabricated using organic-inorganic hybrid materials. The advantages of these solar cells are their low cost and simple fabrication procedure. Also, they have a band gap of about 1.6 eV and effectively absorb light in the visible region. For the commercialization of perovskite solar cells in the field of photovoltaics, the issue of their long term stability cannot be overlooked. Although the development of perovskite solar cells is unprecedented, their main drawback is the degradation of the perovskite structure by moisture. This degradation is accelerated by exposure to UV light, temperature, and external bias. This paper reviews the aforesaid reasons for perovskite solar cell degradation. We also discuss the research directions that can lead to the development of perovskite solar cells with high stability.