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- 저자 : Kosuke Ito (검색결과 6 건)
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Ito, Kosuke,Takahashi, Toru,Fujino, Takayasu,Ishikawa, Motoo The Korean Institute of Electrical Engineers 2014 The Journal of International Council on Electrical Vol.4 No.3
The present paper discusses experimental and numerical studies on the fluid behavior in a magnetohydrodynamic(MHD) micro pump for micro total analysis system(${\mu}$-TAS). In the experiment, the MHD micro pump has a length of 26.0 mm, a width and a height of 0.5 mm. As a working fluid, Phosphate Buffered Saline(PBS) solution is used under the assumption of blood analysis using ${\mu}$-TAS. A neodymium permanent magnet with the maximum magnetic flux density of 0.32 T is used for applying a magnetic field to a channel in the MHD pump. Experimental and numerical results show that Hartmann flow is not observed in the channel because the MHD interaction is very weak, so that Poiseuille flow is maintained in the channel. The numerical study also examines the influences of the channel height and the strength of externally applied magnetic flux density on the fluid temperature in the channel. The numerical results indicate that an increase in fluid temperature by operating the MHD pump is less than 1 K when the magnetic flux density and the channel height are more than 0.3 T and 0.3 mm, respectively.
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Life-cycle analyses of very-large scale PV systems using six types of PV modules
Masakazu Ito,Keiichi Komoto,Kosuke Kurokawa 한국물리학회 2010 Current Applied Physics Vol.10 No.2
The authors have been studied the life-cycle analysis of the VLS-PV systems installed in desert area using sc-Si, mc-Si, a-Si/sc-Si, a-Si/lc-Si, CdTe, and CIS PV modules. The sc-Si and a-Si/sc-Si, a-Si/lc-Si are new items from the last studies [1]. It is assumed 1 GW system in Gobi desert including transmission lines. We estimated energy requirement, energy pay-back time, CO2 emissions, and CO2 emissions rate. Concerning the energy requirement, the CIS is the smallest, and biggest energy requirement is the sc-Si. The mc-Si, a-Si/sc-Si, thin-film Si and CdTe are average. The energy pay-back time of the CIS’s VLS-PV system is approximately 1.8 years, and sc-Si is 2.5 years. The others are approximately 2.0–2.3 years. Characteristics of the CO2 emissions rate are almost same as energy pay-back time. The CO2 emissions rate is 43–54 g-CO2/kW h. The mc-Si, a-Si/sc-Si, and CIS shows lower CO2 emissions rate.
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역학초기화 및 해양결합모델을 이용한 T-PARCII와 Himawari-8 위성을 활용하여 재생산한 상대습도 동화의 효과: 태풍 Lan (2017) 사례
이재덕,박두선,Kosuke Ito,Chun-Chieh Wu 한국기상학회 2021 한국기상학회 학술대회 논문집 Vol.2021 No.10
Tropical cyclones-Pacific Asian Research Campaign for Improvement of Intensity estimations/forecasts (T-PARCII) campaign과 Himawari-8위성 자료를 이용하여 3차원 상대습도를 재생산하고, 그 효과를 Weather research and forecasting (WRF)모델을 이용하여 태풍 Lan (2017)에 대해 조사하였다. WRF모델의 초기 및 경계조건은 Global Forecast System (GFS) 0.25도 예측장을 사용하였다. GFS 초기장을 개선하기 위해, 본 연구에서는 Dynamical initialization (DI, 태풍역학초기화 방법)을 사용하였다. 민감도 실험은 GFS, DI, DI-OCEAN, DI-ARH-OCEAN으로 총 4개로 구성하였다:(DI-OCEAN 실험은 WRF 모델에서 제공하는 3차원 Price-Weller-Pinkel 모델을 활성한 실험; ARH는 the assimilation of relative humidity를 의미함). 총 42시간 수치모의를 수행하였다. 태풍의 진로측면에서 DI-ARH-OCEAN, GFS, DI-OCEAN, DI 순으로 나타났으나, 강도예측에서는 DI-ARH-OCEAN, DI-OCEAN, DI, GFS순으로, 일반적인 재분석장에서는 태풍의 구조나 강도가 약화되어 있는 경향을 보였다. 그러나 0.25도 GFS 예측장도 최소해수면기압에서 급속적응이 보이긴 하지만, 다른 초기화된 실험과 비교하였을 때, 큰 강도차이는 보이지 않았다. Ocean 결합실험에서는 태풍의 오른쪽뒤 사분면에서 해수표면냉각이 관찰되었고, 이는 안정경계층을 형성하였다. 이러한 안정경계층은 태풍의 하층에서 대류발달을 억제하고, 이로 인해 태풍의 약화를 설명하는 메커니즘을 가지고 있다. 총 4가지 민감도 실험을 통해, DI-ARH-OCEAN 실험이 기존의 DI실험과 비교하였을 때 향상된 결과를 보여주었다. 더욱이, DI의 경우 모델 경향을 100% 반영하는 초기화이지만, 본 연구에서 사용된 방법은, DI의 모델경향성을 줄일 수 있을 것으로 사료된다. 이 연구에서 제안하는 마지막 결론은 북서태평양에서의 태풍에 대한 항공기 관측이 정기적으로 수행되어야 할 필요성도 제기하고 있다. 그 이유로, 많은 드랍존데관측과 위성관측을 통해 보다 더 통계적으로 유의한 상대습도 도출이 가능하고, 데이터가 충분히 수집된다면, 위성영상만으로도 충분히 상대습도 도출이 가능하고, DI를 활용하여 태풍의 예측력을 높일 수 있을 것으로 생각되기 때문이다.
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Hiroshi Asano,Katsutoshi Oda,Kosuke Yoshihara,Yoichi M Ito,Noriomi Matsumura,Muneaki Shimada,Hidemichi Watari,Takayuki Enomoto 대한부인종양학회 2022 Journal of Gynecologic Oncology Vol.33 No.4
Background: Poly (adenosine diphosphate)-ribose polymerase (PARP) inhibitors for tumors with homologous recombination deficiency (HRD), including pathogenic mutationsin , have been developed. Genomic analysis revealed that about 20% of uterine leiomyosarcoma (uLMS) have HRD, including 7.5%–10% of alterations and 4%–6% of carcinomas of the uterine corpus, and 2.5%–4% of the uterine cervix have alterations of. Preclinical and clinical case reports suggest that PARP inhibitors may be effective against those targets. The Japanese Gynecologic Oncology Group (JGOG) is now planning to conduct a new investigator-initiated clinical trial, JGOG2052. Methods: JGOG2052 is a single-arm, open-label, multi-center, phase 2 clinical trial to evaluate the efficacy and safety of niraparib monotherapy for a recurrent or persistent rare fraction of gynecologic malignancies with mutations except for ovarian cancers. We will independently consider the effect of niraparib for uLMS or other gynecologic malignancies with mutations (cohort A, C) and HRD positive uLMS without mutations (cohort B). Participants must have 1–3 lines of previous chemotherapy and at least one measurable lesion according to RECIST (v.1.1). Niraparib will be orally administered once a day until lesion exacerbation or unacceptable adverse events occur. Efficacy will be evaluated by imaging through an additional computed tomography scan every 8 weeks. Safety will be measured weekly in cycle 1 and every 4 weeks after cycle 2 by blood tests and physical examinations. The sample size is 16–20 in each of cohort A and B, and 31 in cohort C. Primary endpoint is the objective response rate.
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Quang-Hung Luu,Kosuke Ito,Yoichi Ishikawa,Toshiyuki Awaji 한국해양과학기술원 2011 Ocean science journal Vol.46 No.4
The potential role of the tide-induced time-mean flow (the tidal residual current) in determining transport through the Tsugaru Strait (located between the East/Japan Sea and the North Pacific) is investigated using a high-resolution numerical barotropic model. The calculated K_1, O_1, M_2, and S_2 tidal fields agree well with available observational records derived from both tide gauge and current meter measurements in the strait and the adjacent seas. The tidal residual current speed reaches 0.3 ms^(-1) in two narrow “neck” areas where topographic sills are located. This result suggests that tides should be taken into account in estimating the long-term water mass and nutrient transport through narrow regions between the East/Japan Sea and the North Pacific. An interesting aspect of the tidal residual current field is the prediction of several active eddy zones in which sequences of eddy triplets develop in the vicinity of capes. Our vorticity analysis reveals that the interplay of topographic effects arising from both the headland and the sill around capes plays a critical role in the formation of these triple eddy patterns.
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