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피하조직 삭제술과 CO2 레이저를 이용한 액취증 수술의 임상적 고찰
김상백 ( Sang Baik Kim ),김일환 ( Il Hwan Kim ) 대한피부과학회 2002 大韓皮膚科學會誌 Vol.40 No.12
N/A Background : Axillary osmidrosis is a distressing problem characterized by and unpleasant odor, profuse sweating, and occasionally staining of clothes that may handicap those affected socially, psychologically and in the work place. Various types of surgical procedures have been developed for the treatment of axillary osmidrosis. However, it is still not clear whether which type of surgery can provide the best long-term results. Objective : We evaluated the long-term(more than 2 years) follow-up resole of subcutaneous tissue remover and Carbon Dioxide(CO_2) laser for surgical treatment(Kim`s operative method) of axillary osmidrosis retrospectively. Methods : The number of patients who had been surgically operated wase 132 and among them, 62 patients were interviewed by telephone. The degree of recurrence, scar, satisfaction, the causes of dissatisfaction, and recommendation were evaluated. Results : Thirty-eight of tile 62 patients(61.3%) had no recurrence, Twenty-one patients(33.9%) of the 62 patients had rarely scar, Forty-five patients(72.6%) had a feeling of satisfaction. Conclusion : This combined method has the advantages of a high success rate, low complication rate and Ina scarring for the treatment of axillary osmidrosis baaed on the long-term evaluation. (Korean J Dermatol 2002;40(12) : 1474-1480)
행우서옥본(杏雨書屋本)『황제내경태소(黃帝內經太素)』 권(卷)21, 권(卷)27의 출간(出刊) 의의(意義)와 그 내용에 대한 고찰(考察)
김종현 ( Jong Hyun Kim ),백유상 ( You Sang Baik ),장우창 ( Woo Chang Jang ),정창현 ( Chang Hyun Jeong ) 대한한의학원전학회(구 대한원전의사학회) 2011 대한한의학원전학회지 Vol.24 No.5
『Hwangjenaegyeong-taeso(黃帝內經太素)』 is a classic work of Yang Sang-seon(楊上善), which comprises original articles of 『Hwangjenaegyeong(黃帝內經)』 along with 『Somun(素問)』, 『Yeongchu (靈樞)』, and 『gapeul(甲乙)』, as a one of the oldest annotated publications. Therefore, its significance lies in that 『Hwangjenaegyeong-taeso(黃帝內經太素)』 is a valuable work to reconstruct the original text of 『Hwangjenaegyeong(黃帝內經)』 and comprehend its fundamental ideas. The only printed edition of 『Hwangjenaegyeong-taeso(黃帝內經太素)』 was photocopied in 1981, and is currently known as ``Orient Edition``. While ``Orient Edition`` was referred to as the draft for the latest revised edition, volume 21 and 27 were photocopied from hand-copied edition, not the original. The original publications of ``Orient Edition`` have been stocked at ``Haengwuseook(杏雨書屋)`` of Japan and were recently published. Hence, a comparative study between the two original volumes and the former ones has been conducted. Although the most of the differences were trivial, some may have led to distorted interpretation of the text. The errors of the former revised edition fall into a few specific categories, and the most significant ones were errors that were made during the hand-copying procedure. Moreover, there were errors that were made due to the low resolution of the former draft, and simple errors during the publishing. In this work, examples of such cases were presented, and the results were collected.
Changing prevalence of upper gastrointestinal disease in 28 893 Koreans from 1995 to 2005
Kim, Jin Il,Kim, Sang Gyun,Kim, Nayoung,Kim, Jae Gyu,Shin, Sung Jae,Kim, Sang Woo,Kim, Hyun Soo,Sung, Jae Kyu,Yang, Chang Heon,Shim, Ki-Nam,Park, Seun Ja,Park, Joon Yong,Baik, Gwang Ho,Lee, Sang Woo,P Lippincott Williams Wilkins, Inc. 2009 European journal of gastroenterology & hepatology Vol.21 No.7
OBJECTIVES: Changes in the pattern of gastrointestinal diseases in a population tend to be influenced by changes in diet and lifestyle. Shifts in gastrointestinal disease from 1995 to 2005 in Korea were evaluated, retrospectively. METHODS: Seventeen nationwide medical centers participated in this study. The cross-sectional review of endoscopic findings in 28 893 patients included 8441 patients from 1995, 10 350 patients from 2000, and 10 102 patients from 2005. RESULTS: The prevalence of reflux esophagitis increased from 1.8% in 1995 to 5.9% in 2000 and 9.1% in 2005 (P<0.001, the P value was only for the comparison between 1995 and 2005, the followings were as same). The prevalence of peptic ulcer diseases was 18.0% in 1995, 19.1% in 2000, and 20.2% in 2005 (P<0.001). Although no significant differences were noted in duodenal ulcers (8.4, 8.7, and 8.2%, P=0.449), gastric ulcers showed an increasing trend (9.6, 10.5, and 12.0%, P<0.001). The prevalence of gastric cancer increased from 3.4% in 1995 to 4.5% in 2000 (P<0.001), but then decreased to 2.4% in 2005 (P<0.001). The incidence of advanced gastric cancer was 2.5, 3.2, and 1.3%, respectively (P<0.001), and that of early gastric cancer remained constant with rates of 0.8%, 1.3, and 1.1%, respectively (P=0.056). CONCLUSION: The cross-sectional review of data collected in 1995, 2000, and 2005 showed an increase in reflux esophagitis and peptic ulcer diseases. Meanwhile, the prevalence of gastric cancer increased until 2000, but decreased in 2005.
경성여자의학전문학교 창립의 주체였던 김탁원,길정희부부는 왜 실제 설립 과정에서 제외되었는가?
백운기 ( Woon Kee Baik ),김상덕 ( Sang Duk Kim ) 연세대학교 의과대학 의사학과 의학사연구소 2010 연세의사학 Vol.13 No.1
Chosun (a.k.a. Keijo) Women``s Medical Training Institute was founded in 1928 as a joint effort between an American missionary physician named Dr. Rosetta Sherwood Hall and one of Korea’s first female physicians, Dr. Kil Chung-Hee. In 1932, in anticipation of her retirement, Dr. Hall transferred full responsibility for the Institute to Dr. Kil and her husband Dr. Kim Taik-Won, a neuropsychiatrist. Unfortunately, following Dr. Hall``s departure to America in 1933, funding from Dr. Hall’s missionary society was discontinued. This prompted an evacuation of the Institute’s lecture halls and teaching laboratories. As a result of this change in finances, the Institute’s operations were transported to, and maintained exclusively at, Drs. Kim and Kil``s private residence. During this interim period, the institute was sustained financially by this husband and wife team. In addition to these new found financial difficulties, there were ongoing political hardships. In an effort to alleviate these various difficulties, the couple decided to pursue the task of upgrading the Institute to a standard medical college. As a first step toward this goal, in 1934, the couple established a foundation for the “creation of a women``s medical college”. This undertaking (i.e., the creation of a medical college) required a large amount of funding. Therefore, the couple became actively engaged in the solicitation of funding for this purpose. In 1937, an education philanthropist named Mr. Kim Chong-Ik agreed to donate substantial funds for the purpose of establishing the women’s medical college. As fate would have it, however, / 49 he unexpectedly contracted dysentery and died suddenly. The application for the creation of a women``s medical college was filed and approved in 1938 by the Japanese Governor-General. Thus, the first class of students in the newly created medical college was enrolled on May 1, 1938. Curiously, however, neither Dr. Kim nor Dr. Kil was named in the charter. Although one could presuppose various reasons to explain how this omission occurred, there is one undeniable aspect of history that makes clear and cogent sense in this regard. It is now known that Dr. Kim was a leading activist for Korean independence from Japan during the 1920’s and 1930’s. He was regarded as an agitator by the Japanese occupation government and viewed as an undesirable, rebellious, anti-Japanese element. The South Korean government, in recognition of his heroic deeds during that period of Japanese occupation, posthumously awarded the Ae-Jok Jan(humanitarian award) to Dr. Kim Taik-Won on August 15, 2007. On July 4, 2008, his remains were subsequently transferred, along with his professional partner and wife Dr. Kil Chung-Hee, to the Korean National Cemetery in Daejon, South Korea. If one considers the political climate that existed in Korea in the late 1930’s under Japanese occupation, it stands to reason that any medical college application that included an anti-Japanese activist such as Kim Taik-Won would be doomed to fail. I believe that the absence of Drs. Kim Taik-Won and Kil Chung-Hee’s names from the medical college charter was a rational, politically motivated act of omission.
Physician-Directed Diabetes Education without a Medication Change and Associated Patient Outcomes
Kim, Hun-Sung,Kim, Hyunah,Yang, Hae-Kyung,Lee, Eun Young,Jeong, Yoo Jin,Kim, Tong Min,Yang, So Jung,Baik, Seo Yeon,Lee, Seung-Hwan,Cho, Jae Hyoung,Choi, In Young,Yim, Hyeon Woo,Cha, Bong-Yun Korean Diabetes Association 2017 Diabetes and Metabolism Journal Vol.41 No.3
<P><B>Background</B></P><P>When patients with diabetes mellitus (DM) are first referred to a hospital from primary health care clinics, physicians have to decide whether to administer an oral hypoglycemic agent (OHA) immediately or postpone a medication change in favor of diabetes education regarding diet or exercise. The aim of this study was to determine the effect of diabetes education alone (without alterations in diabetes medication) on blood glucose levels.</P><P><B>Methods</B></P><P>The study was conducted between January 2009 and December 2013 and included patients with DM. The glycosylated hemoglobin (HbA1c) levels were evaluated at the first visit and after 3 months. During the first medical examination, a designated doctor also conducted a diabetes education session that mainly covered dietary management.</P><P><B>Results</B></P><P>Patients were divided into those who received no diabetic medications (<I>n</I>=66) and those who received an OHA (<I>n</I>=124). Education resulted in a marked decrease in HbA1c levels in the OHA group among patients who had DM for <1 year (from 7.0%±1.3% to 6.6%±0.9%, <I>P</I>=0.0092) and for 1 to 5 years (from 7.5%±1.8% to 6.9%±1.1%, <I>P</I>=0.0091). Those with DM >10 years showed a slightly lower HbA1c target achievement rate of <6.5% (odds ratio, 0.089; <I>P</I>=0.0024).</P><P><B>Conclusion</B></P><P>For patients who had DM for more than 5 years, higher doses or changes in medication were more effective than intensive active education. Therefore, individualized and customized education are needed for these patients. For patients with a shorter duration of DM, it may be more effective to provide initial intensive education for diabetes before prescribing medicines, such as OHAs.</P>
Kim Jongtae,Hong Seong-Wan,Kim Sang-Baik,Kim Hee-Dong,Lee Unjang,Royl P.,Travis J. R. Korean Nuclear Society 2004 Nuclear Engineering and Technology Vol.36 No.1
In order to analyze the hydrogen distribution during a severe accident in the APR1400 containment, GASFLOW II was used. For the APR1400 NPP, a hydrogen mitigation system is considered from the design stage, but a fully time-dependent, three-dimensional analysis has not been performed yet. In this study GASFLOW code II is used for the three-dimensional analysis. The first step to analysis involving hydrogen behavior in a full containment with the GASLOW code is to generate a realistic geometry model, which includes nodalization and modeling of the internal structures such as walls, ceilings and equipment. Geometry modeling of the APR1400 is conducted using GUI program by overlapping the containment cut drawings in a graphical file format on the mesh view. The total number of mesh cells generated is 49,476. And the calculated free volume of the APR1400 containment by GASFLOW is almost the same as the value from the GOTHIC modeling. A hypothetical SB-LOCA scenario beyond design base accident was selected to analyze the hydrogen behavior with the hydrogen mitigation system. The source of hydrogen and steam for the GASFLOW II analysis is obtained from a MAAP calculation. Combustion pressure and temperature load possibilities within the compartments used in the GOTHIC analysis are studied based on the Sigma-Lambda criteria. Finally the effectiveness of HMS installed in the APR1400 containment is evaluated from the point of severe accident management
Kim, Sang Ryong,Chung, Eun Sook,Bok, Eugene,Baik, Hyung Hwan,Chung, Young Cheul,Won, So Yoon,Joe, Eunhye,Kim, Tae Hyong,Kim, Soung Soo,Jin, Min Young,Choi, Sang Ho,Jin, Byung Kwan Wiley Subscription Services, Inc., A Wiley Company 2010 JOURNAL OF NEUROSCIENCE RESEARCH - Vol.88 No.7
<P>We have shown that prothrombin kringle-2 (pKr-2), a domain of human prothrombin distinct from thrombin could activate cultured rat brain microglia in vitro. However, little is known whether pKr-2-induced microglial activation could cause neurotoxicity on dopaminergic (DA) neurons in vivo. To address this question, pKr-2 was injected into the rat substantia nigra (SN). Tyrosine hydroxylase (TH) immunohistochemistry experiments demonstrate significant loss of DA neurons seven days after injection of pKr-2. In parallel, pKr-2-activated microglia were detected in the SN with OX-42 and OX-6 immunohistochemistry. Reverse transcription PCR and double-label immunohistochemistry revealed that activated microglia in vivo exhibit early and transient expression of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2) and several proinflammatory cytokines. The pKr-2-induced loss of SN DA neurons was partially inhibited by the NOS inhibitor N<SUP>G</SUP>-nitro-L-arginine methyl ester hydrochloride, and the COX-2 inhibitor DuP-697. Extracellular signal-regulated kinase 1/2, c-Jun N-terminal kinase and p38 mitogen-activated protein kinase were activated in the SN as early as 1 hr after pKr-2 injection, and localized within microglia. Inhibition of these kinases led to attenuation of mRNA expression of iNOS, COX-2 and several proinflammatory cytokines, and rescue of DA neurons in the SN. Intriguingly, following treatment with pKr-2 in vitro, neurotoxicity was detected exclusively in co-cultures of mesencephalic neurons and microglia, but not microglia-free neuron-enriched mesencephalic cultures, indicating that microglia are required for pKr-2 neurotoxicity. Our results strongly suggest that microglia activated by endogenous compound(s), such as pKr-2, are implicated in the DA neuronal cell death in the SN. © 2009 Wiley-Liss, Inc.</P>