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피하조직 삭제술과 CO2 레이저를 이용한 액취증 수술의 임상적 고찰
김상백 ( Sang Baik Kim ),김일환 ( Il Hwan Kim ) 대한피부과학회 2002 大韓皮膚科學會誌 Vol.40 No.12
N/A Background : Axillary osmidrosis is a distressing problem characterized by and unpleasant odor, profuse sweating, and occasionally staining of clothes that may handicap those affected socially, psychologically and in the work place. Various types of surgical procedures have been developed for the treatment of axillary osmidrosis. However, it is still not clear whether which type of surgery can provide the best long-term results. Objective : We evaluated the long-term(more than 2 years) follow-up resole of subcutaneous tissue remover and Carbon Dioxide(CO_2) laser for surgical treatment(Kim`s operative method) of axillary osmidrosis retrospectively. Methods : The number of patients who had been surgically operated wase 132 and among them, 62 patients were interviewed by telephone. The degree of recurrence, scar, satisfaction, the causes of dissatisfaction, and recommendation were evaluated. Results : Thirty-eight of tile 62 patients(61.3%) had no recurrence, Twenty-one patients(33.9%) of the 62 patients had rarely scar, Forty-five patients(72.6%) had a feeling of satisfaction. Conclusion : This combined method has the advantages of a high success rate, low complication rate and Ina scarring for the treatment of axillary osmidrosis baaed on the long-term evaluation. (Korean J Dermatol 2002;40(12) : 1474-1480)
행우서옥본(杏雨書屋本)『황제내경태소(黃帝內經太素)』 권(卷)21, 권(卷)27의 출간(出刊) 의의(意義)와 그 내용에 대한 고찰(考察)
김종현 ( Jong Hyun Kim ),백유상 ( You Sang Baik ),장우창 ( Woo Chang Jang ),정창현 ( Chang Hyun Jeong ) 대한한의학원전학회(구 대한원전의사학회) 2011 대한한의학원전학회지 Vol.24 No.5
『Hwangjenaegyeong-taeso(黃帝內經太素)』 is a classic work of Yang Sang-seon(楊上善), which comprises original articles of 『Hwangjenaegyeong(黃帝內經)』 along with 『Somun(素問)』, 『Yeongchu (靈樞)』, and 『gapeul(甲乙)』, as a one of the oldest annotated publications. Therefore, its significance lies in that 『Hwangjenaegyeong-taeso(黃帝內經太素)』 is a valuable work to reconstruct the original text of 『Hwangjenaegyeong(黃帝內經)』 and comprehend its fundamental ideas. The only printed edition of 『Hwangjenaegyeong-taeso(黃帝內經太素)』 was photocopied in 1981, and is currently known as ``Orient Edition``. While ``Orient Edition`` was referred to as the draft for the latest revised edition, volume 21 and 27 were photocopied from hand-copied edition, not the original. The original publications of ``Orient Edition`` have been stocked at ``Haengwuseook(杏雨書屋)`` of Japan and were recently published. Hence, a comparative study between the two original volumes and the former ones has been conducted. Although the most of the differences were trivial, some may have led to distorted interpretation of the text. The errors of the former revised edition fall into a few specific categories, and the most significant ones were errors that were made during the hand-copying procedure. Moreover, there were errors that were made due to the low resolution of the former draft, and simple errors during the publishing. In this work, examples of such cases were presented, and the results were collected.
Changing prevalence of upper gastrointestinal disease in 28 893 Koreans from 1995 to 2005
Kim, Jin Il,Kim, Sang Gyun,Kim, Nayoung,Kim, Jae Gyu,Shin, Sung Jae,Kim, Sang Woo,Kim, Hyun Soo,Sung, Jae Kyu,Yang, Chang Heon,Shim, Ki-Nam,Park, Seun Ja,Park, Joon Yong,Baik, Gwang Ho,Lee, Sang Woo,P Lippincott Williams Wilkins, Inc. 2009 European journal of gastroenterology & hepatology Vol.21 No.7
OBJECTIVES: Changes in the pattern of gastrointestinal diseases in a population tend to be influenced by changes in diet and lifestyle. Shifts in gastrointestinal disease from 1995 to 2005 in Korea were evaluated, retrospectively. METHODS: Seventeen nationwide medical centers participated in this study. The cross-sectional review of endoscopic findings in 28 893 patients included 8441 patients from 1995, 10 350 patients from 2000, and 10 102 patients from 2005. RESULTS: The prevalence of reflux esophagitis increased from 1.8% in 1995 to 5.9% in 2000 and 9.1% in 2005 (P<0.001, the P value was only for the comparison between 1995 and 2005, the followings were as same). The prevalence of peptic ulcer diseases was 18.0% in 1995, 19.1% in 2000, and 20.2% in 2005 (P<0.001). Although no significant differences were noted in duodenal ulcers (8.4, 8.7, and 8.2%, P=0.449), gastric ulcers showed an increasing trend (9.6, 10.5, and 12.0%, P<0.001). The prevalence of gastric cancer increased from 3.4% in 1995 to 4.5% in 2000 (P<0.001), but then decreased to 2.4% in 2005 (P<0.001). The incidence of advanced gastric cancer was 2.5, 3.2, and 1.3%, respectively (P<0.001), and that of early gastric cancer remained constant with rates of 0.8%, 1.3, and 1.1%, respectively (P=0.056). CONCLUSION: The cross-sectional review of data collected in 1995, 2000, and 2005 showed an increase in reflux esophagitis and peptic ulcer diseases. Meanwhile, the prevalence of gastric cancer increased until 2000, but decreased in 2005.
경성여자의학전문학교 창립의 주체였던 김탁원,길정희부부는 왜 실제 설립 과정에서 제외되었는가?
백운기 ( Woon Kee Baik ),김상덕 ( Sang Duk Kim ) 연세대학교 의과대학 의사학과 의학사연구소 2010 연세의사학 Vol.13 No.1
Chosun (a.k.a. Keijo) Women``s Medical Training Institute was founded in 1928 as a joint effort between an American missionary physician named Dr. Rosetta Sherwood Hall and one of Korea’s first female physicians, Dr. Kil Chung-Hee. In 1932, in anticipation of her retirement, Dr. Hall transferred full responsibility for the Institute to Dr. Kil and her husband Dr. Kim Taik-Won, a neuropsychiatrist. Unfortunately, following Dr. Hall``s departure to America in 1933, funding from Dr. Hall’s missionary society was discontinued. This prompted an evacuation of the Institute’s lecture halls and teaching laboratories. As a result of this change in finances, the Institute’s operations were transported to, and maintained exclusively at, Drs. Kim and Kil``s private residence. During this interim period, the institute was sustained financially by this husband and wife team. In addition to these new found financial difficulties, there were ongoing political hardships. In an effort to alleviate these various difficulties, the couple decided to pursue the task of upgrading the Institute to a standard medical college. As a first step toward this goal, in 1934, the couple established a foundation for the “creation of a women``s medical college”. This undertaking (i.e., the creation of a medical college) required a large amount of funding. Therefore, the couple became actively engaged in the solicitation of funding for this purpose. In 1937, an education philanthropist named Mr. Kim Chong-Ik agreed to donate substantial funds for the purpose of establishing the women’s medical college. As fate would have it, however, / 49 he unexpectedly contracted dysentery and died suddenly. The application for the creation of a women``s medical college was filed and approved in 1938 by the Japanese Governor-General. Thus, the first class of students in the newly created medical college was enrolled on May 1, 1938. Curiously, however, neither Dr. Kim nor Dr. Kil was named in the charter. Although one could presuppose various reasons to explain how this omission occurred, there is one undeniable aspect of history that makes clear and cogent sense in this regard. It is now known that Dr. Kim was a leading activist for Korean independence from Japan during the 1920’s and 1930’s. He was regarded as an agitator by the Japanese occupation government and viewed as an undesirable, rebellious, anti-Japanese element. The South Korean government, in recognition of his heroic deeds during that period of Japanese occupation, posthumously awarded the Ae-Jok Jan(humanitarian award) to Dr. Kim Taik-Won on August 15, 2007. On July 4, 2008, his remains were subsequently transferred, along with his professional partner and wife Dr. Kil Chung-Hee, to the Korean National Cemetery in Daejon, South Korea. If one considers the political climate that existed in Korea in the late 1930’s under Japanese occupation, it stands to reason that any medical college application that included an anti-Japanese activist such as Kim Taik-Won would be doomed to fail. I believe that the absence of Drs. Kim Taik-Won and Kil Chung-Hee’s names from the medical college charter was a rational, politically motivated act of omission.
Kim, Yong Seok,Park, Sang Woon,Kim, Min Ho,Jang, Eun Jeong,Park, Ju Sang,Park, Sang Jong,Baik, Hyun Wook,Chung, Gregory,Hahm, Ki Baik Blackwell Publishing Asia 2008 Journal of gastroenterology and hepatology Vol.23 No.suppl2
<P>Abstract</P><P>Background and Aim: </P><P>The gastroduodenal ulcer (GDU) mostly develops on the lesser curvature side of stomach and the anterior wall of duodenal bulb, irrespective of the etiologies including <I>Helicobacter pylori</I> infection, non-steroidal anti-inflammatory drugs, alcohol, etc. However, a clear explanation as to why ulcers are prevalent in these areas has still not been given. The current study was designed to evaluate whether the vascular endothelial growth factor (VEGF) polymorphism could predict susceptibility to GDU through deranged angiogenic activities.</P><P>Methods: </P><P>A large scale case-control study based on known single nucleotide polymorphisms (SNP) of VEGF and another case control study based on the novel SNP of VEGF was performed through the SNP-IT assay using the SNP stream 25 k system. A site-directed mutagenesis and functional assay was executed to document the biological effect of a novel VEGF SNP on angiogenesis.</P><P>Results: </P><P>Even though the case-control study between non-ulcer dyspepsia (NUD) and gastric ulcer (GU) patients was done in 10 SNP of the <I>VEGF</I> gene including −2488C/T, −634G/C, −7C/T, 3436G/C, 6112C/A, 6894C/T, 9374G/A, 9812C/T, 13128C/T, and 13553C/T, the analysis showed no statistically significant association between NUD and GU. Denaturing high-performance liquid chromatography analysis could identify two novel SNP of the <I>VEGF</I> gene, −1780T/C and <I>IVS-</I>99 G/C, among which −1780T/C showed a very strong association between NUD and GDU, presenting with OR = 2.93 on codominant analysis (<I>P</I> < 0.001), OR = 8.62 on dominant analysis (<I>P</I> < 0.001), and OR = 3.21 on recessive analysis (<I>P</I> < 0.001). The promoter assay using a site-directed mutagenesis and <I>in vitro</I> angiogenesis assay showed repressed transcription of the <I>VEGF</I> gene in gastric epithelial cells and defective tube formation in endothelial cells, both transfected with a plasmid containing −1780C/C mutant of VEGF gene.</P><P>Conclusion: </P><P>The novel VEGF polymorphism −1780T/C could significantly predict the predisposition to GDU after the exposure to etiologic risks, based on defective angiogenic activity.</P>
Isolation and Structural Determination of Squalene Synthase Inhibitor from Prunus mume Fruit
( Sung Won Choi ),( Nam Yoon Hur ),( Soon Cheol Ahn ),( Dong Seob Kim ),( Jae Kwon Lee ),( Dae Ok Kim ),( Seung Kook Park ),( Byung Yong Kim ),( Moo Yeol Baik ) 한국미생물생명공학회 2007 Journal of microbiology and biotechnology Vol.17 No.12