푸코-데리다의 광기 논쟁에 대한 ‘데리다적’ 독해 -「코기토와 광기의 역사」 다시 읽기-

김민호(Kim, Minho) 서울대학교 철학사상연구소 2021 철학사상 Vol.79 No.-

우리의 목적은 「코기토와 광기의 역사」를 데리다라는 사상가 ‘의’ 텍스트로서 읽음으로써 이 텍스트를 해석할 때 주로 푸코의 이후의 저작들에 조회하는 김은주의 논의를 일정하게 보충하는 데에 있다. 우리는 「코기토와 광기의 역사」에 선행하는 데리다의 두 저작, 즉 『발생의 문제』 및 『《기하학의 기원》에 대한 서설』에서 출발해서 이 논쟁에 개입한다. 이를 위해 우리는 『발생의 문제』 및 『서설』에서 푸코가 데리다를 비판하는 논점들이 앞질러 예고됨을 (2장), 그 함축에 입각하여 「코기토와 광기의 역사」가 감행하는 독해의 의의를 규명하면서 푸코의 데리다에 대한 비판이 데리다에게는 여전히 미진함을(3장), 마지막으로 데리다야말로 『성찰』을 하나의 사건으로 만들고 있음을(4장) 보인다. This article aims to complement Eunju Kim’s reading of “Cogito and the History of Madness,” oriented towards Foucault’s later works, by examining it in the light of Derrida’s early writings on Husserl’s thought, i.e. The Problem of Genesis in Husserl’s Philosophy and Introduction to Husserl’s Origin of Geometry. It argues that the basis of Foucault’s critique of Derrida’s interpretation of Meditations on First Philosophy, as reconstructed by Kim, is not far from that of Derrida’s own philosophy (II). From this viewpoint, Foucault’s critique is refuted in advance within the scope of “Cogito and the History of Madness” (III), which implies that, contrary to what Foucault and Kim believe, Derrida is the one who makes Descartes’ Meditations “an event worthy of its name” (IV).

Exploring the Microbial Community and Functional Characteristics of the Livestock Feces Using the Whole Metagenome Shotgun Sequencing

Kim Hyeri,Kim Eun Sol,Cho Jin Ho,Song Minho,Cho Jae Hyoung,Kim Sheena,Keum Gi Beom,Kwak Jinok,Doo Hyunok,Pandey Sriniwas,Park Seung-Hwan,Lee Ju Huck,Hyunjung Jung,Hur Tai Young,Kim Jae-Kyung,Oh Kwang 한국미생물·생명공학회 2023 Journal of microbiology and biotechnology Vol.33 No.1

The foodborne illness is the important public health concerns, and the livestock feces are known to be one of the major reservoirs of foodborne pathogens. Also, it was reported that 45.5% of foodborne illness outbreaks have been associated with the animal products contaminated with the livestock feces. In addition, it has been known that the persistence of a pathogens depends on many potential virulent factors including the various virulent genes. Therefore, the first step to understanding the public health risk of livestock feces is to identify and describe microbial communities and potential virulent genes that contribute to bacterial pathogenicity. We used the whole metagenome shotgun sequencing to evaluate the prevalence of foodborne pathogens and to characterize the virulence associated genes in pig and chicken feces. Our data showed that the relative abundance of potential foodborne pathogens, such as Bacillus cereus was higher in chickens than pigs at the species level while the relative abundance of foodborne pathogens including Campylobacter coli was only detected in pigs. Also, the microbial functional characteristics of livestock feces revealed that the gene families related to “Biofilm formation and quorum sensing” were highly enriched in pigs than chicken. Moreover, the variety of gene families associated with “Resistance to antibiotics and toxic compounds” were detected in both animals. These results will help us to prepare the scientific action plans to improve awareness and understanding of the public health risks of livestock feces.

Ultrareliable and Low-Latency Communication Techniques for Tactile Internet Services

Kim, Kwang Soon,Kim, Dong Ku,Chae, Chan-Byoung,Choi, Sunghyun,Ko, Young-Chai,Kim, Jonghyun,Lim, Yeon-Geun,Yang, Minho,Kim, Sundo,Lim, Byungju,Lee, Kwanghoon,Ryu, Kyung Lin IEEE 2019 Proceedings of the Institute of Electrical and Ele Vol.107 No.2

<P>This paper presents novel ultrareliable and low-latency communication (URLLC) techniques for URLLC services, such as Tactile Internet services. Among typical use cases of URLLC services are teleoperation, immersive virtual reality, cooperative automated driving, and so on. In such URLLC services, new kinds of traffic such as haptic information including kinesthetic information and tactile information need to be delivered in addition to high-quality video and audio traffic in traditional multimedia services. Furthermore, such a variety of traffic has various characteristics in terms of packet sizes and data rates with a variety of requirements of latency and reliability. Furthermore, some traffic may occur in a sporadic manner but requires reliable delivery of packets of medium to large sizes within a low latency, which is not supported by current state-of-the-art wireless communication systems and is very challenging for future wireless communication systems. Thus, to meet such a variety of tight traffic requirements in a wireless communication system, novel technologies from the physical layer to the network layer need to be devised. In this paper, some novel physical layer technologies such as waveform multiplexing, multiple-access scheme, channel code design, synchronization, and full-duplex transmission for spectrally efficient URLLC are introduced. In addition, a novel performance evaluation approach, which combines a ray-tracing tool and system-level simulation, is suggested for evaluating the performance of the proposed schemes. Simulation results show the feasibility of the proposed schemes providing realistic URLLC services in realistic geographical environments, which encourages further efforts to substantiate the proposed work.</P>

THE IMPACT OF WEB DRAMA CHARACTERISTICS ON REUSE INTENTION

Minho Kim,Sejin Heo,Junyeong Kim,Changyong Lee,Dohyeon Lee,Mujin Kang,Kyunghoon Kim 글로벌지식마케팅경영학회 2018 Global Marketing Conference Vol.2018 No.07

Internet communication technology has encouraged social services and media industry to develop in various aspects. Web drama is one of them, which is characterized by mobility, immediacy, and personality, and provided with popular contents regardless of time or place. In addition, it includes various themes such as work, romance, thriller, zombie, and homosexuality. This study aims to examine what web drama characteristics affect consumer behavior. Data was collected from university students in south korea. who are main viewers of web drama. The respondents to this study consist of random sample respondents from college students in their 20s. A total of 200 samples were surveyed, and a voluntary participant. The data are analyzed by the SPSS 21.0. Short running time, convenience, contents diversity, accessibility, review, and grade are defineded as characteristics of web drama. Acording to the analysis of data. Web drama characteristics have a positive impact on reuse intention. Consumer engagement mediates the relationship between web drama characteristics and reuse intention. PPL moderates the relationship between web drama characteristics and reuse intention. The results of this study are expected to provide both the researchers and marketing practitioners with the framework to understand why and how web drama works on watching intention.

Transforming Growth Factor-β-Induced RBFOX3 Inhibition Promotes Epithelial-Mesenchymal Transition of Lung Cancer Cells

Kim, Yong-Eun,Kim, Jong Ok,Park, Ki-Sun,Won, Minho,Kim, Kyoon Eon,Kim, Kee K. Korean Society for Molecular and Cellular Biology 2016 Molecules and cells Vol.39 No.8

The RNA-binding protein Rbfox3 is a well-known splicing regulator that is used as a marker for post-mitotic neurons in various vertebrate species. Although recent studies indicate a variable expression of Rbfox3 in non-neuronal tissues, including lung tissue, its cellular function in lung cancer remains largely unknown. Here, we report that the number of RBFOX3-positive cells in tumorous lung tissue is lower than that in normal lung tissue. As the transforming growth factor-${\beta}$ (TGF-${\beta}$) signaling pathway is important in cancer progression, we investigated its role in RBFOX3 expression in A549 lung adenocarcinoma cells. TGF-${\beta}1$ treatment inhibited RBFOX3 expression at the transcriptional level. Further, RBFOX3 depletion led to a change in the expression levels of a subset of proteins related to epithelial-mesenchymal transition (EMT), such as E-cadherin and Claudin-1, during TGF-${\beta}1$-induced EMT. In immunofluorescence microscopic analysis, mesenchymal morphology was more prominent in RBFOX3-depleted cells than in control cells. These findings show that TGF-${\beta}$-induced RBFOX3 inhibition plays an important role in EMT and propose a novel role for RBFOX3 in cancer progression.

Development and validation of an LC-MS/MS method for determination of compound K in human plasma and clinical application

Kim, Jung Soo,Kim, Yunjeong,Han, Song-Hee,Jeon, Ji-Young,Hwang, Minho,Im, Yong-Jin,Kim, Jung Hyun,Lee, Sun Young,Chae, Soo-Wan,Kim, Min-Gul The Korean Society of Ginseng 2013 Journal of Ginseng Research Vol.37 No.1

A rapid, sensitive and selective analytical method was developed and validated for the determination of compound K, a major intestinal bacterial metabolite of ginsenosides in human plasma. Liquid-liquid extraction was used for sample preparation and analysis, followed by liquid chromatography tandem spectrometric analysis and an electrospray-ionization interface. Compound K was analyzed on a Phenomenex Luna C18 column ($100{\times}2.00$ mm, 3 ${\mu}m$) with the mobile phase run isocratically with 10 mM ammonium acetate-methanol-acetonitrile (5:47.5:47.5, v/v/v) at a flow rate of 0.5 mL/min. The method was validated for accuracy (relative error <12.63%), precision (coefficient of variation <9.14%), linearity, and recovery. The assay was linear over the entire range of calibration standards i.e., a concentration range of 1 ng/mL to 1,000 ng/mL ($r^2$ >0.9968). The recoveries of compound K after liquid-liquid extraction at 1, 2, 400, and 800 ng/mL were $106.00{\pm}0.08%$, $103.50{\pm}0.19%$, $111.45{\pm}5.21%$, and $89.62{\pm}34.46%$ for intra-day and $85.40{\pm}0.08%$, $94.50{\pm}0.09%$, $112.50{\pm}5.21%$, and $95.87{\pm}34.46%$ for inter-day, respectively. The lower limit of quantification of the analytical method of compound K was 1 ng/mL in human plasma. The developed method was successfully applied to a pharmacokinetic study of compound K after oral administration in ten of healthy human subjects.

A dual gated WSeu₂ field-effect transistors with graphene as the top gate electrode

Taekwang KIM,Hyewon DU,Somyung SHIN,Seonyeong KIM,Minho SONG,Sangmin KIM,Seungjun KIM,Sunae SEO 한국진공학회 2016 한국진공학회 학술발표회초록집 Vol.2016 No.8

함산소 연료첨가제 종류에 따른 연료 물성 및 배기배출 특성

이민호(Minho Lee),김성우(Sungwoo Kim),김재권(Jaigueon Kim),김종렬(Jongryeol kim),임의순(Euisoon Yim),김동길(Donggil Kim) 한국자동차공학회 2009 한국자동차공학회 부문종합 학술대회 Vol.2009 No.4

As the interest on the air pollution is gradually rising up at home and abroad, automotive and fuel researchers have been working on the exhaust emission reduction from vehicles through a lot of approaches, which consist of new engine design, innovative after-treatment systems, using clean (eco-friendly alternative) fuels and fuel quality improvement. This research has brought forward two main issues : exhaust emission and PM particle emissions of gasoline vehicle. Exhaust emission and PM(particulate matter) particle of automotive had many problem that cause of ambient pollution, health effects. The main particulate fraction of automotive exhaust emission consists of small particles. Because of their small size, inhaled particles may easily penetrate deep into the lungs. The rough surfaces of these particles make it easy for them to bind with other toxins in the environment, thus increasing the hazards of particle inhalation. Based on the oxygenated fuel types (MTBE, Bio-ETBE, Bio-ethanol, Bio-butanol), this paper discussed the influence of oxygen contents on gasoline vehicle exhaust and nano-particle emissions. Also, this paper assessed exhaust emission characteristics using 2 type test mode. The test modes were CVS-75 and HWFET mode.

Synthesis of vertical MnO₂ wire arrays on hemp-derived carbon for efficient and robust green catalysts

Yang, MinHo,Kim, Dong Seok,Sim, Jae-Wook,Jeong, Jae-Min,Kim, Do Hyun,Choi, Jae Hyung,Kim, Jinsoo,Kim, Seung-Soo,Choi, Bong Gill Elsevier BV * North-Holland 2017 Applied Surface Science Vol.407 No.-

<P><B>Abstract</B></P> <P>Three-dimensional (3D) carbon materials derived from waste biomass have been attracted increasing attention in catalysis and materials science because of their great potential of catalyst supports with respect to multi-functionality, unique structures, high surface area, and low cost. Here, we present a facile and efficient way for preparing 3D heterogeneous catalysts based on vertical MnO<SUB>2</SUB> wires deposited on hemp-derived 3D porous carbon. The 3D porous carbon materials are fabricated by carbonization and activation processes using hemp (<I>Cannabis Sttiva</I> L.). These 3D porous carbon materials are employed as catalyst supports for direct deposition of vertical MnO<SUB>2</SUB> wires using a one-step hydrothermal method. The XRD and XPS results reveal the crystalline structure of α-MnO<SUB>2</SUB> wires. The resultant composites are further employed as a catalyst for glycolysis of poly(ethylene terephthalate) (PET) with high conversion yield of 98%, which is expected to be expressly profitable for plastics recycling industry.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The three-dimensional nanocomposites based on vertical MnO<SUB>2</SUB> array on hemp-derived carbon (HDC) were prepared by hydrothermal method. </LI> <LI> The 3D v-MnO<SUB>2</SUB>/HDC nanocomposites showed well-defined porous nature with a high specific surface area of 382.3m<SUP>2</SUP> g<SUP>−1</SUP>. </LI> <LI> PET glycolysis was performed using the 3D v-MnO<SUB>2</SUB>/HDC nanocomposites as a catalyst, leading to efficient catalytic performance. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Proteomic analysis for the effects of non-saponin fraction with rich polysaccharide from Korean Red Ginseng on Alzheimer's disease in a mouse model

Sujin Kim,Yunkwon Nam,Min-jeong Kim,Seung-hyun Kwon,Junhyeok Jeon,Soo Jung Shin,Soyoon Park,Sungjae Chang,Hyun Uk Kim,Yong Yook Lee,Hak Su Kim,Minho Moon The Korean Society of Ginseng 2023 Journal of Ginseng Research Vol.47 No.2

Background: The most common type of dementia, Alzheimer's disease (AD), is marked by the formation of extracellular amyloid beta (Aβ) plaques. The impairments of axons and synapses appear in the process of Aβ plaques formation, and this damage could cause neurodegeneration. We previously reported that non-saponin fraction with rich polysaccharide (NFP) from Korean Red Ginseng (KRG) showed neuroprotective effects in AD. However, precise molecular mechanism of the therapeutic effects of NFP from KRG in AD still remains elusive. Methods: To investigate the therapeutic mechanisms of NFP from KRG on AD, we conducted proteomic analysis for frontal cortex from vehicle-treated wild-type, vehicle-treated 5XFAD mice, and NFP-treated 5XFAD mice by using nano-LC-ESI-MS/MS. Metabolic network analysis was additionally performed as the effects of NFP appeared to be associated with metabolism according to the proteome analysis. Results: Starting from 5,470 proteins, 2,636 proteins were selected for hierarchical clustering analysis, and finally 111 proteins were further selected for protein-protein interaction network analysis. A series of these analyses revealed that proteins associated with synapse and mitochondria might be linked to the therapeutic mechanism of NFP. Subsequent metabolic network analysis via genome-scale metabolic models that represent the three mouse groups showed that there were significant changes in metabolic fluxes of mitochondrial carnitine shuttle pathway and mitochondrial beta-oxidation of polyunsaturated fatty acids. Conclusion: Our results suggested that the therapeutic effects of NFP on AD were associated with synaptic- and mitochondrial-related pathways, and they provided targets for further rigorous studies on precise understanding of the molecular mechanism of NFP.