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박준성 ( Junseong Park ),서영일 ( Young Il Seo ),장충식 ( Choong Sik Jang ),박병수 ( Byung Soo Park ),박상식 ( Sang Sik Park ),안영수 ( Young Su An ),박준수 ( Junsu Park ),강명희 ( Myounghee Kang ) 한국어업기술학회 2016 수산해양기술연구 Vol.52 No.2
Acoustic surveys using a scientific echosounder and trawl surveys were concurrently carried out in between Geoje and Tongyeong of the South Sea by season. The anchovy schools were identified by trawling in each station and used for frequency response analysis. Frequency responses of anchovy schools by season and species composition ratio were examined using multi-frequencies (18, 38, 70, 120 and 200 kHz). The frequency response r(f), is one of the acoustic characteristics which means the volume back-scattering strength ratio between a reference frequency and other frequencies. In spring, the r(f) of anchovy schools decreased with increased frequency, with the exception of 120kHz. While, in winter, the r(f) continuously decreased inversely proportional to the increase in frequency. Frequency response of anchovy schools presented a distinctive difference between spring and winter, however it did not different in spife of different species composition ratios in schools.
박준성 ( Junseong Park ),이정훈 ( Jeong Hoon Lee ),김두남 ( Doo Nam Kim ),박영글 ( Yeongguel Park ),장충식 ( Choong Sik Jang ),박병수 ( Byung Soo Park ),강명희 ( Myounghee Kang ) 한국수산해양기술학회 2015 수산해양기술연구 Vol.51 No.3
The hydro-acoustic technology has been widely used in not only South Korea but also many foreign countries for various scientific purposes. Unfortunately acoustic data especially collected from field surveys may contain noises caused by a variety of sources. Therefore, it is exceedingly important to eliminate noises when acoustic data are analyzed to derive quantitative results. This study introduced two methods for eliminating noises easily and effectively using post-processing software. Used acoustic data were collected on the Jinhae bay and Tongyeong coast of the South Sea in April 2015. The first method, that is the Wang’s method, placed emphasis on ‘erosion filter’ to eliminate only data samples contaminated by noises. The second method (Yamandu’s method) focused on the ‘resample by number of pings’ to remove pings contained noises. To substantiate the effectiveness of two methods, the mean Sv (Volume backscattering strength), mean height and depth of the fish schools detected were compared between before and after using the noise elimination methods. In the Wang’s method the mean Sv was decreased from -52.4 dB to -52.9 dB, and in the Yamandu’s method from -52.6 dB to -53.3 dB, indicating that noises were successfully eliminated. The mean height (1.5 m) and depth (19.0 m) were same between before and after using two methods showing that the shapes of fish schools were not changed.
Junseong Park,Sung H. Han,Kyudong Park 대한인간공학회 2018 대한인간공학회 학술대회논문집 Vol.2018 No.5
Automated vehicles can perform many parts of driving tasks that used to be managed by a human driver these days. However, it is important to calibrate appropriate levels of trust to make drivers accept the technology. The aim of this study is to derive design factors for the automated vehicles to calibrate trust based on literature reviews. This study is a fundamental one in automated vehicles before their commercialization, and conducted literature reviews to find factors estimating trust and factors determining trust. As a result, a total of 12 trust estimating factors were found: deceptive, underhanded manner, suspicious, wary, harmful or injurious outcome, confident, security, integrity, dependable, reliable, trust, and familiar. and they were categorized into five representative groups: performance, experience, information, faults, and display. This study can be used to calibrate trust of automated vehicles.
Park Junseong,Kim Yoon-Seob,Zhang Songzi,Kim Dokyeong,Shin Sun,Lee Sug Hyung,Chung Yeun-Jun 한국유전학회 2023 Genes & Genomics Vol.45 No.9
Background Although cytoreductive surgery followed by adjuvant chemotherapy is effective as a standard treatment for early-stage ovarian cancer, the majority of ovarian cancer cases are diagnosed at the advanced stages with dissemination to the peritoneal cavity, leading to a poor prognosis. Therefore, it is crucial to understand the cellular and molecular mechanisms underlying metastasis and identify novel therapeutic targets. Objective In this study, we aimed to elucidate the mechanisms underlying gene expression alterations during the acquisition of metastatic potential and characterize the metastatic subpopulations within ovarian cancer cells. Methods We conducted single-cell RNA sequencing of two human ovarian cancer cell lines: SKOV-3 and SKOV-3-13, a highly metastatic subclone of SKOV-3. Suppression of NFE2L1 expression was performed through siRNA-mediated knockdown and CRISPR-Cas9-mediated knockout. Results Clustering and pseudotime trajectory analysis revealed pro-metastatic subpopulation within these cells. Furthermore, gene set enrichment analysis and prognosis analysis indicated that NFE2L1 could be a key transcription factor in the acquisition of metastasis potential. Inhibition of NFE2L1 significantly reduced migration and viability of both cells. In addition, NFE2L1 knockout cells exhibited significantly reduced tumor growth in a mouse xenograft model, recapitulating in silico and in vitro results. Conclusion The results presented in this study deepen our understanding of the molecular pathogenesis of ovarian cancer metastasis with the ultimate goal of developing treatments targeting pro-metastatic subclones prior to metastasis.
Butadiene Polymerization Catalyzed by Tri(aryloxo)aluminum Adduct of Cobalt Acetate
Park, Ji Hae,Kim, Ahreum,Jun, Sung Hae,Kwag, Gwanghoon,Park, Ka Hyun,Lee, Junseong,Lee, Bun Yeoul Korean Chemical Society 2012 Bulletin of the Korean Chemical Society Vol.33 No.12
Tris(2-phenylphenoxo)aluminum ($(2-PhC_6H_4O)_3Al$) exists as a dimeric form in toluene. When toluene-insoluble anhydrous cobalt acetate is treated with tris(2-phenylphenoxo)aluminum in toluene, the toluene-soluble adduct $(2-PhC_6H_4O)_3Al{\cdot}Co(OAc)_2$ is formed. The 2-phenylphenoxo ligand in the adduct can be replaced with another aryloxo ligand to give (aryloxo)$(2-PhC_6H_4O)_2Al{\cdot}Co(OAc)_2$ (aryloxo = 2-methylphenoxo, 2-isopropylphenoxo, 4-methylphenoxo, 4-isopropylphenoxo, or 4-tert-butylphenoxo). These complexes are active for butadiene polymerization without gel formation when activated with an equivalent amount of $(2-PhC_6H_4O)AlEt_2$ for 2 h. The highest activity, 175 kg/mol-Co (turnover number, 3200) was achieved with $(2-PhC_6H_4O)_3Al{\cdot}Co(OAc)_2$ at $65^{\circ}C$ for 2 h. The microstructure of the polymer chains is mostly trans-1,4-configuration (70-75%) with the remaining being 1,2-vinyl. The cis-1,4-configuration observed by IR is minimal (1-5%). By replacing the 2-phenylpheoxo with a 4-alkylphenoxo ligand, the amount of 1,4-configuration slightly increases, resulting in increase in the endothermic melting signal at $-30{\sim}50^{\circ}C$ in the DSC curve. The molecular weights of the polymers are high ($M_n$: 300000~800000) with a fairly narrow molecular weight distribution ($M_w/M_n$, 2.0-2.7).