Facile One-Pot Synthesis and Optical Properties of Quinary Wurtzite Cu3ZnInSnS6 Nanocrystals

Dehui Li,Chen Zhang,Yajie Zhang,Weichen Qi,Jinxiang Dong,Jing Yang,Zhidong Qiu 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2016 NANO Vol.11 No.11

Nearly monodisperse bullet-like Cu3ZnInSnS6 (CZITS) nanocrystals with wurtzite structure were successfully synthesized through optimized noninjection method. The structure, composition, morphology and optical properties of CZITS nanocrystals were characterized by X-ray diffraction, energy dispersive spectrometry, transmission electron microscopy and UV-Vis–NIR absorption. Their suitable bandgap and photoresponsive behavior indicate a high potential application in the field of solar cells. The growth mechanism of the as-synthesized CZITS nanocrystals was preliminarily discussed. It was found that the formation of CZITS could be separated into two steps: nucleation of Cu7S4 and growth of the CZITS main body.

Response of Glucocorticoid Receptor Alpha and Histone Deacetylase 2 to Glucocorticoid Treatment Predicts the Prognosis of Sudden Sensorineural Hearing Loss

Xiuling Zhang,Jinxiang Chen,Ziwen Gao,Hui Qi,Yanhong Dai,Wandong She 대한이비인후과학회 2019 Clinical and Experimental Otorhinolaryngology Vol.12 No.4

Objectives. To investigate glucocorticoid receptor (GR) and histone deacetylase 2 (HDAC2) gene expression and protein levels in peripheral blood mononuclear cells (PBMCs) of patients with severe or profound sudden sensorineural hearing loss (SSNHL) and to explore the roles of GRs and HDAC2 in glucocorticoid (GC) insensitivity. Methods. Fifty-five severe or profound SSNHL patients were enrolled in the study. According to hearing improvement after GC treatment, patients were assigned into two groups: GC-sensitive and GC-resistant. A normal reference group included 20 healthy volunteers without hearing loss. Quantitative real-time polymerase chain reaction and Western blot analyses were used to detect the relative expression of GRα, GRβ, and HDAC2 in PBMCs at the mRNA and protein levels. Results. The protein levels of GRs and HDAC2 in PBMCs of SSNHL patients were lower than the normal reference values before GC treatment. Compared with the GC-resistant group, both the mRNA and protein levels of GRα and HDAC2 were significantly increased in the GC-sensitive group after GC treatment. Conclusion. A lack of GRα and HDAC2 induction following steroid treatment in GC-resistant SSNHL patients may play a fundamental mechanistic role in GC insensitivity. Response of GRα and HDAC2 to steroid treatment may, thus, predict the prognosis of hearing improvement in SSNHL patients.

A Study of Radio Voice Signal Based on the Time Delay Estimation

Xinrui Liu,Jinxiang Chen,Xianbo He,Wei Li,Gangyuan Zhang 보안공학연구지원센터 2016 International Journal of Hybrid Information Techno Vol.9 No.9

The wave of voice signal is narrow and unstable. Besides, it has a non-continuity in time domain and an inconsistent decline of the radio channel, especially the short wave channel, which makes estimating the time delay of the radio’s voice signal very difficult. To solve such problems, the authors creatively combine the voice activity detection with the short-segment processing technology. Meanwhile, by using Weighted Least Squares Phase Fitting method to work out the time delay, we conduct a research in the time delay estimation of radio’s voice signal. The laboratory finding finally shows that this method is far better than the typical Generalized Correlation Method for estimation of time delay.

Identification of Endogenous Genes for Normalizing Titer Variation of Citrus Tristeza Virus in Aphids at Different Post-acquisition Feeding Times

Hongsu Wang,Qi Chen,Luqin Liu,Yan Zhou,Huanhuan Wang,Zhongan Li,Jinxiang Liu 한국식물병리학회 2022 Plant Pathology Journal Vol.38 No.4

Citrus tristeza virus (CTV) is efficiently transmitted in a semi-persistent manner by the brown citrus aphid (Toxoptera citricida (Kirkaldy)). Currently, the most sensitive method for detecting plant viruses in insect vectors is reverse-transcription quantitative polymerase chain reaction (RT-qPCR). In this study, the elongation factor-1 alpha (EF-1α) gene and acidic p0 ribosomal protein (RPAP0) gene were confirmed to be suitable reference genes for RT-qPCR normalization in viruliferous T. citricida aphids using the geNorm, NormFinder, and BestKeeper tools. Then the relative CTV titer in aphids (T. citricida) at different post-acquisition feeding times on healthy plants was quantified by RT-qPCR using EF-1α and RPAP0 as reference genes. The relative CTV titer retained in the aphids gradually decreased with increasing feeding time. During the first 0.5 h of feeding time on healthy plants, the remaining CTV titer in aphids showed about 80% rapid loss for the highly transmissible isolate CT11A and 40% loss for the poorly transmissible isolate CTLJ. The relative CTV titer in aphids during more than 12 h post-acquisition times for CT11A was significantly lower than at the other feeding times, which is similar to the trend found for CTLJ. To our knowledge, this is the first report about the relative titer variation of CTV remaining in T. citricida at different post-acquisition feeding times on healthy plants.

Optimization of the Structural Parameters of the Vertical Trabeculae Beetle Elytron Plate Based on the Mechanical and Thermal Insulation Properties

Zhijie Zhang,Elbashiry Mohamed Adam Elsafi,Jinxiang Chen,Peixing Wei,Yaqin Fu 대한토목학회 2020 KSCE JOURNAL OF CIVIL ENGINEERING Vol.24 No.12

According to the excellent structure of the beetle elytron plate (BEP), a new type of bionic prefabricated wallboard with vertical trabeculae and honeycomb walls (the vertical trabeculae beetle elytron plate: VBEPsc) was proposed. The relationships between the main structural parameters, including the concrete frame thickness (T), honeycomb wall thickness (t), trabecula number (N) and trabecular radius (R), and the performance of the VBEPsc were analyzed. In addition, to improve the mechanical and insulation performance of the VBEPsc, an initial optimal design was determined. The results showed that 1) in addition to the mechanical properties of the VBEPsc being mainly affected by T, as is known, N had an apparent impact on the stiffness of the VBEPsc; the insulation performance was affected greatly by T, N, and t. 2) Under the given conditions, the mechanical properties of the optimized VBEPsc met the requirements for bearing capacities and serviceability; The insulation performance of the optimized VBEPsc met the requirements for self-insulating walls of category II buildings in areas that are cold in winter and hot in summer. In addition, a double-layer mold and complete production technology for VBEPsc were proposed. These works started a discussion for the application of such prefabricated wallboards.

Investigation of (n,α) Reaction for Rare-earth Elements in the MeV Neutron Energy Region

Y. Gledenov,M. Sedysheva,Guohui Zhang,Jiaguo Zhang,Hao Wu,Jiaming Liu,Jinxiang Chen,P. Koehler,G. Khuukhenkhuu,P. Szalanski 한국물리학회 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.59 No.23

Cross sections and forward/backward ratios in the laboratory reference system were measured for ^(143)Nd(n,α)^(140)Ce at 4.0, 5.0, and 6.0 MeV, ^(147)Sm(n,α)^(144)Nd at 5.0 and 6.0 MeV, and ^(149)Sm(n,α)^(146)Nd at 6.0 MeV. A twin gridded ionization chamber and large-area back-to-back ^(143)Nd^2O^3 and ^(147,149)Sm^2O^3 samples were employed. Experiments were performed at the 4.5 MV Van de Graaff of Peking University, China. Fast neutrons were produced through the D(d, n)^3He reaction by using a deuterium gas target. A small ^(238)U fission chamber was employed for absolute neutron flux determination and a BF_3 long counter was used as neutron flux monitor. Present experimental data are compared with previous measurements, evaluations, and model calculations.

Ginseng berry polysaccharides on infl ammation-associated colon cancer: inhibiting T-cell differentiation, promoting apoptosis, and enhancing the effects of 5-fl uorouracil

Chong-Zhi Wang,Lifei Hou,Jin-Yi Wan,Haiqiang Yao,Jinbin Yuan,Jinxiang Zeng,Chan Woong Park,Su Hwan Kim,Dae Bang Seo,Kwang-Soon Shin,Chun-Feng Zhang,Lina Chen,Qi-Hui Zhang,Zhi Liu,Clara Sava-Segal,Chun 고려인삼학회 2020 Journal of Ginseng Research Vol.44 No.2

Background: Ginseng is a commonly used herbal medicine in treating various medical conditions. Chronic gut inflammation is a recognized factor for the development of colorectal cancer (CRC). In thisproject, Asian ginseng berry polysaccharide preparations were used to assess their effects on CRC andrelated immune regulation mechanisms. Methods: Ginseng berry polysaccharide extract (GBPE) and purified ginseng berry polysaccharideportion (GBPP) were used to evaluate their activities on human HCT-116 and HT-29 CRC cell proliferation. Interleukin-8 secretion analysis was performed on HT-29 cells. Naive CD4 cell isolation and T-helper celldifferentiation were performed and determined using flow cytometry for Th1 and Treg in addition to cellcycle and apoptotic investigation. Results: GBPE and GBPP significantly inhibited interleukin-8 secretion and cancer cell proliferation,inhibited CD4þIFN-gþ cell (Th1) differentiation, and decreased CD4þFoxP3þ cell (Treg) differentiation. Compared to the GBPE, GBPP showed more potent antiinflammatory activities on the malignant cells. This is consistent with the observation that GBPP can also inhibit Th1-cell differentiation better, suggestingthat it has an important role in antiinflammation, whereas Treg cells hinder the body’s immuneresponse against malignancies. Supported by cell cycle and apoptosis data, GBPE and GBPP, at variousdegrees, remarkably enhanced the anticancer activities of 5-fluorouracil. Conclusion: Data from this project suggested that Asian ginseng berry potentially has clinical utility inmanaging enteric inflammation and suppressing CRC through immunomodulation mechanisms.

^(64)Zn and ^(67)Zn (n,α) Reactions in the MeV Neutron Energy Region

Guohui Zhang,Jiaguo Zhang,Hao Wu,Jiaming Liu,Jinxiang Chen,Yuri Gledenov,Milana Sedysheva,Gonchigdorj Khuukhenkhuu,Pavel Szalanski 한국물리학회 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.59 No.23

Nuclear reactions of ^(64)Zn(n,α)^(61)Ni and ^(67)Zn(n,α)^(64)Ni are important because they are gas pro-duction reactions and zinc is a reactor constituent element with a signicant fraction. But the cross section data of these reactions are scanty because the residual nuclei ^(61)Ni and ^(64)Ni are stable and the commonly used activation method is not feasible. In the present work, differential cross sections and angleintegrated cross sections were measured for the ^(64)Zn(n,α)^(61)Ni reaction at neutron energies of 2.5, 4.0, 5.0, 5.5, and 6.0 MeV and cross sections of the ^(67)Zn(n,α)^(64)Ni reaction were measured at 4.0, 5.0, and 6.0 MeV. A twin gridded ionization chamber was employed as alpha particle detector. Experiments were performed at the 4.5 MV Van de Graaff accelerator of Peking University. Monoenergetic neutrons of 2.5 MeV were produced through the T(p, n)^3He reaction with a solid Ti-T target, and those of other energies were produced through the D(d, n)^3He reaction with a deuterium gas target. Absolute neutron fluxes were determined through the ^(238)U(n, f) reaction and a BF^3 long counter was used as the neutron flux monitor. Present results are compared with other measurements and evaluations.

Ginseng berry polysaccharides on inflammation-associated colon cancer: inhibiting T-cell differentiation, promoting apoptosis, and enhancing the effects of 5-fluorouracil

Wang, Chong-Zhi,Hou, Lifei,Wan, Jin-Yi,Yao, Haiqiang,Yuan, Jinbin,Zeng, Jinxiang,Park, Chan Woong,Kim, Su Hwan,Seo, Dae Bang,Shin, Kwang-Soon,Zhang, Chun-Feng,Chen, Lina,Zhang, Qi-Hui,Liu, Zhi,Sava-Se The Korean Society of Ginseng 2020 Journal of Ginseng Research Vol.44 No.2

Background: Ginseng is a commonly used herbal medicine in treating various medical conditions. Chronic gut inflammation is a recognized factor for the development of colorectal cancer (CRC). In this project, Asian ginseng berry polysaccharide preparations were used to assess their effects on CRC and related immune regulation mechanisms. Methods: Ginseng berry polysaccharide extract (GBPE) and purified ginseng berry polysaccharide portion (GBPP) were used to evaluate their activities on human HCT-116 and HT-29 CRC cell proliferation. Interleukin-8 secretion analysis was performed on HT-29 cells. Naive CD4 cell isolation and T-helper cell differentiation were performed and determined using flow cytometry for Th1 and Treg in addition to cell cycle and apoptotic investigation. Results: GBPE and GBPP significantly inhibited interleukin-8 secretion and cancer cell proliferation, inhibited CD4⁺IFN-γ⁺ cell (Th1) differentiation, and decreased CD4⁺FoxP3⁺ cell (Treg) differentiation. Compared to the GBPE, GBPP showed more potent antiinflammatory activities on the malignant cells. This is consistent with the observation that GBPP can also inhibit Th1-cell differentiation better, suggesting that it has an important role in antiinflammation, whereas Treg cells hinder the body's immune response against malignancies. Supported by cell cycle and apoptosis data, GBPE and GBPP, at various degrees, remarkably enhanced the anticancer activities of 5-fluorouracil. Conclusion: Data from this project suggested that Asian ginseng berry potentially has clinical utility in managing enteric inflammation and suppressing CRC through immunomodulation mechanisms.