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RISS 인기검색어
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- 저자 : Sava-Se (검색결과 2 건)
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High performance GaAs metal-insulator–semiconductor devices using TiO2 as insulator layer
Savaş Sönmezoğlu,Seçkin Akın 한국물리학회 2012 Current Applied Physics Vol.12 No.5
In the present study, Cu/TiO2/n-GaAs Metal-InsulatoreSemiconductor (MIS) structure was fabricated and the variation in electrical characteristics of this structure have been analyzed as a function of temperature using currentevoltage (I-V) measurements in the temperature range 50e290 K with a steps of 40 K. It has shown that the ideality factor (n) was decreased with increasing temperature, however, the zero-bias barrier height (Φb,0) was increased with increasing temperature. Furthermore, Gaussian potential model was used in order to explain the barrier height inhomogeneity observed in this structure. This discrepancy could be explained by local inhomogeneities at the metal-semiconductor interface by considering fluctuations in the local surface potential. This value of Richardson constant, obtained the modified Richardson plot in the first region (290-170 K) according to the Gaussian distribution (GD), is in excellent agreement with the theoretical value for n-type GaAs. These results show that understanding the temperature dependence electrical characteristics of this structure may be of great help in improving the quality of TiO2 grown on GaAs substrates for the future of the device technology. In the present study, Cu/TiO2/n-GaAs Metal-InsulatoreSemiconductor (MIS) structure was fabricated and the variation in electrical characteristics of this structure have been analyzed as a function of temperature using currentevoltage (I-V) measurements in the temperature range 50e290 K with a steps of 40 K. It has shown that the ideality factor (n) was decreased with increasing temperature, however, the zero-bias barrier height (Φb,0) was increased with increasing temperature. Furthermore, Gaussian potential model was used in order to explain the barrier height inhomogeneity observed in this structure. This discrepancy could be explained by local inhomogeneities at the metal-semiconductor interface by considering fluctuations in the local surface potential. This value of Richardson constant, obtained the modified Richardson plot in the first region (290-170 K) according to the Gaussian distribution (GD), is in excellent agreement with the theoretical value for n-type GaAs. These results show that understanding the temperature dependence electrical characteristics of this structure may be of great help in improving the quality of TiO2 grown on GaAs substrates for the future of the device technology.
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Wang, Chong-Zhi,Hou, Lifei,Wan, Jin-Yi,Yao, Haiqiang,Yuan, Jinbin,Zeng, Jinxiang,Park, Chan Woong,Kim, Su Hwan,Seo, Dae Bang,Shin, Kwang-Soon,Zhang, Chun-Feng,Chen, Lina,Zhang, Qi-Hui,Liu, Zhi,Sava-Se The Korean Society of Ginseng 2020 Journal of Ginseng Research Vol.44 No.2
Background: Ginseng is a commonly used herbal medicine in treating various medical conditions. Chronic gut inflammation is a recognized factor for the development of colorectal cancer (CRC). In this project, Asian ginseng berry polysaccharide preparations were used to assess their effects on CRC and related immune regulation mechanisms. Methods: Ginseng berry polysaccharide extract (GBPE) and purified ginseng berry polysaccharide portion (GBPP) were used to evaluate their activities on human HCT-116 and HT-29 CRC cell proliferation. Interleukin-8 secretion analysis was performed on HT-29 cells. Naive CD4 cell isolation and T-helper cell differentiation were performed and determined using flow cytometry for Th1 and Treg in addition to cell cycle and apoptotic investigation. Results: GBPE and GBPP significantly inhibited interleukin-8 secretion and cancer cell proliferation, inhibited CD4<sup>+</sup>IFN-γ<sup>+</sup> cell (Th1) differentiation, and decreased CD4<sup>+</sup>FoxP3<sup>+</sup> cell (Treg) differentiation. Compared to the GBPE, GBPP showed more potent antiinflammatory activities on the malignant cells. This is consistent with the observation that GBPP can also inhibit Th1-cell differentiation better, suggesting that it has an important role in antiinflammation, whereas Treg cells hinder the body's immune response against malignancies. Supported by cell cycle and apoptosis data, GBPE and GBPP, at various degrees, remarkably enhanced the anticancer activities of 5-fluorouracil. Conclusion: Data from this project suggested that Asian ginseng berry potentially has clinical utility in managing enteric inflammation and suppressing CRC through immunomodulation mechanisms.
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