Influence of Interface Structure on Dielectric Properties of Epoxy/Alumina Nanocomposites

Jinhong Yu,Genglin Wang,Ruimei Huo,Chao Wu,Xinfeng Wu,Pingkai Jiang 한국고분자학회 2012 Macromolecular Research Vol.20 No.8

Alumina (Al2O3) nanoparticles with three different interface structures have been selected as reinforcement fillers for epoxy nanocomposite, that is surface untreated Al2O3 nanoparticles, γ-aminopropyl-triethoxysilane modified Al2O3 nanoparticles (Al2O3-APS), and hyperbranched aromatic polyamide grafted Al2O3 nanoparticles (Al2O3-HBP). The interface structures of the Al2O3 nanoparticles were characterized by X-ray diffraction and atomic force micrographs. Our studies reported the influence of the interface structure of Al2O3 nanoparticles on the morphology and dielectric properties of epoxy nanocomposites. It was found that the incorporation of the Al2O3-APS and Al2O3-HBP nanoparticles not only improved the dispersion of the nanoparticles in the epoxy matrix, but also enhanced the glass transition temperatures (Tgs) and largely influenced the dielectric properties of the epoxy nanocomposites as compared with the nanocomposites filled with the surface untreated Al2O3 nanoparticles. The improvement of Tgs, volume resistivity, dielectric strength, and the reduction of dielectric loss could be attributed to the good dispersion and special interface structure of the Al2O3 nanoparticles in the epoxy matrix.

A Keyword Filters Method for Spam via Maximum Independent Sets

HaiLong Wang,FanJun Meng,HaiPeng Jia,JinHong Cheng,Jiong Xie 보안공학연구지원센터 2013 International Journal of Smart Home Vol.7 No.3

Piperine as a Potential Nutraceutical Agentfor Managing Diabetes and Its Complications: A Literature Review

Yujie Wang,Shan Xu,Lidan Tang,Jinhong Gong,Dan Su,Hao Yang 한국식품영양과학회 2023 Journal of medicinal food Vol.26 No.10

The global prevalence of diabetes and its related complications has increased drastically and is currently aworldwide health challenge. There is still an urgent need for safe and effective natural products and supplements as alternativeand/or adjunctive therapeutic interventions. Nowadays, people pay more and more attention to the nutritional and medicinalvalue of food ingredients. As one of the most widely employed spices in cooking, pepper also has novel medicinal valuesattributed to its main component, piperine (Pip). Pip is an amide alkaloid with pleiotropic properties such as antiinflammatory,antioxidant, anti-cancer, and other related activities. Recently, Pip has received increasing scientific attentiondue to its antidiabetic and related complication properties. However, the values of existing studies are limited due to beingscattered and unsystematic. The present study reviewed the therapeutic potential and possible mechanisms of Pip in diabetesand related complications, with the aim of providing promising candidates for the development of novel and effectivealternative and/or adjunctive nutraceutical agents for the management of diabetes.

Efficient Immobilization of Enzymes on Amino Functionalized MIL-125-NH2 Metal Organic Framework

Zichen Wang,Yang Liu,Jinhong Li,Guoqing Meng,Daoyu Zhu,Jiandong Cui,Shi Ru Jia 한국생물공학회 2022 Biotechnology and Bioprocess Engineering Vol.27 No.1

As a series of metal organic framework (MOFs), materials of institute lavoisier frameworks (MILs) are expected to be excellent supports for enzyme immobilization due to their good water-stability and acid tolerance. However, enzyme loading on MIL-125-NH2 is very low due to small pore size and few amino groups on the surface of the MIL-125-NH2. In this work, catalase (CAT) was immobilized on the MIL-125-NH2 and amino functionalized MIL-125-NH2 by adsorption (CAT@MIL-125-NH2) and covalent binding (CAT@Amino MIL-125-NH2), respectively. Compared with the CAT@MIL-125-NH2 and free CAT, the CAT@Amino MIL-125-NH2 displayed high activity recovery, good pH stability, stability against denaturants, and thermostability. Furthermore, activity recovery of CAT@Amino MIL-125-NH2 was 56% higher than CAT@MIL-125-NH2. The CAT@Amino MIL-125-NH2 still retained 50% residual activity for 14 days at room temperature, whereas free CAT lost activity after storage for 1 day at the same storage conditions. Furthermore, the CAT@Amino MIL-125-NH2 maintained 62% of its initial activity after 4 consecutive uses, showing good reusability. The results showed that the amino functionalized MIL- 125-NH2 is an excellent carrier of enzyme immobilization.

Enhanced Thermal and Mechanical Properties of Polyimide/Graphene Composites

Wen Dai,Jinhong Yu,Yi Wang,Yingze Song,Hua Bai,Kazuhito Nishimura,Huiwei Liao,Nan Jiang 한국고분자학회 2014 Macromolecular Research Vol.22 No.9

Polyimide (PI)/graphene sheets (GSs) composites were prepared by solution blending. The incorporationof GSs into PI increased the thermal conductivity, thermal stability and mechanical properties of PI. The thermal conductivityof PI/GSs composites was significantly improved compared with that of neat PI from 0.254 to 1.002 W/mK; this can be attributed to the homogeneous dispersion of graphene and the formation of heat conduction pathway. Furthermore, the Young modulus of PI/GSs was raised up to 4.04 GPa, approximately two-fold enhancement incomparison with that of neat PI. In addition, the incorportation of GSs in PI indicated excellent optical transparencyat the lowest weight fractions of GSs and modified wettability of PI films.

Physical Layer Security in Heterogeneous Cellular Networks

Hui-Ming Wang,Tong-Xing Zheng,Jinhong Yuan,Towsley, Don,Moon Ho Lee IEEE 2016 IEEE TRANSACTIONS ON COMMUNICATIONS Vol.64 No.3

<P>The heterogeneous cellular network (HCN) is a promising approach to the deployment of 5G cellular networks. This paper comprehensively studies physical layer security in a multitier HCN where base stations (BSs), authorized users, and eavesdroppers are all randomly located. We first propose an access threshold-based secrecy mobile association policy that associates each user with the BS providing the maximum truncated average received signal power beyond a threshold. Under the proposed policy, we investigate the connection probability and secrecy probability of a randomly located user and provide tractable expressions for the two metrics. Asymptotic analysis reveals that setting a larger access threshold increases the connection probability while decreases the secrecy probability. We further evaluate the network-wide secrecy throughput and the minimum secrecy throughput per user with both connection and secrecy probability constraints. We show that introducing a properly chosen access threshold significantly enhances the secrecy throughput performance of a HCN.</P>

Dynamical Expression of MicroRNA-127-3p in Proliferating and Differentiating C2C12 Cells

Li, Jie,Wang, Gaofu,Jiang, Jing,Zhou, Peng,Liu, Liangjia,Zhao, Jinhong,Wang, Lin,Huang, Yongfu,Ma, Youji,Ren, Hangxing Asian Australasian Association of Animal Productio 2016 Animal Bioscience Vol.29 No.12

MicroRNAs (miRNAs) are highly conserved, short non-coding RNAs that regulate gene expression at the posttranscriptional level. Although many miRNAs are identified in muscles and muscle cells, their individual roles are still not fully understood. In the present study, we investigated a muscle highly-expressed miRNA, miR-127-3p, in C2C12 myoblasts and tissues of goats with different muscle phenotypes (Boer vs Wushan black goats). Our results demonstrated that i) miR-127-3p was extensively expressed in tissues of goats; ii) miR-127-3p was higher expressed in muscle, spleen, heart, and skin in the muscular goats (Boer goats) than the control (Wushan black goats). Then we further characterized the dynamical expression of miR-127-3p, MyoD, MyoG, Myf5, Mef2c, and Myosin in the proliferating and differentiating C2C12 myoblasts at day of 0, 1, 3, 5, and 7 in culture mediums. Especially, we found that miR-127-3p was significantly higher expressed in the proliferating than differentiating cells. Our findings suggest that miR-127-3p probably plays roles in the proliferation and differentiation of myoblasts, which further underlies regulation of muscle phenotype in goats.

Ketogenic Diet in Infants with Early-Onset Epileptic Encephalopathy and SCN2A Mutation

Xiaoyu Tian,Yange Zhang,Jinhong Zhang,Yan Lu,Xinyi Men,Xiuxia Wang 연세대학교의과대학 2021 Yonsei medical journal Vol.62 No.4

Research has shown mutations in the voltage-gated sodium channel gene SCN2A to be associated with developmental delaysand infantile seizures in patients with early-onset epileptic encephalopathies (EOEEs). Here, we report the case of an infant witha de novo SCN2A mutation with EOEE who had medically refractory seizures that improved with a ketogenic diet (KD) implementedat an age less than 2 months. On the day of his birth, the infant presented with a pattern of convulsions with dozens ofepisodes per day. An initial video electroencephalogram revealed poor reactivity of background activity, with multiple partial episodesstarting from the right temporal region, and abnormal electrical activity in the right hemisphere. The seizures previouslywere not controlled with successive therapy with phenobarbital, topiramate, and levetiracetam. Genetic testing revealed the presenceof a mutation in the SCN2A gene (c.4425C>G, p.Asn1475Lys). The infant’s seizures decreased significantly with a combinationof KD and medication. The present case exemplifies the potential for personalized genomics in identifying the etiology of anillness. Furthermore, the KD appears to feasible in infants younger than 2 months and might elicit good responses to EOEE associatedwith SCN2A mutation.

Research of Electronic Power Information System Based-on Multi-core Processors

FanJun Meng,HaiLong Wang,JinHong Cheng,Jiong Xie 보안공학연구지원센터 2013 International Journal of Control and Automation Vol.6 No.3

Effects of TLR9/NF-κB on oxidative stress and inflammation in IPEC-J2 cells

Ma Lixia,Geng Jinhong,Chen Wei,Qin Ming,Wang Lixue,Zeng Yongqing 한국유전학회 2022 Genes & Genomics Vol.44 No.10

Background: Oxidative stress is one of the most important factors affecting large-scale breeding, especially the performance of pigs. Oxidative stress plays a role by affecting various genes in pigs, which can cause serious body damage, functional degradation and reduce production performance. Objective: The purpose of this study was to investigate the effect of Toll like receptor 9 (TLR9) pathway on IPEC-J2 cells under oxidative stress and to provide reference for the growth development of Dapulian pigs. Methods: In this study, Diquat was used as a source of oxidative stress to study the effects on Dapulian pigs by detecting relevant indicators. Then the IPEC-J2 cells were selected to verify the TLR9 signaling pathway in oxidative stress. Results: Compared with the control group, superoxide dismutase (SOD) in experimental group decreased significantly, malondialdehyde (MDA) was significantly increased, accompanied by inflammatory reaction, and inflammatory factors were significantly increased in the experimental group. Oxidative stress model was constructed by H2O2 incubating IPEC-J2 cells. The interference and overexpression vectors of TLR9 and myeloid differentiation primary response protein 88 (MyD88) were constructed to detect the activity of antioxidant enzymes and related proteins. The results showed that overexpression of TLR9 enhanced the activity of antioxidant enzymes, decreased the secretion of inflammatory factors, and decreased the activity of MDA,reactive oxygen species (ROS); the results were opposite after TLR9 interference. This study also showed that H2O2 can activate the nuclear factor-κB (NF-κB) pathway and promote the translocation of NF-κB into the nucleus. After co-transfection with TLR9 and MyD88, the results showed that TLR9 regulated the expression of NF-κB through MyD88. Conclusion: The study showed that TLR9 pathway had a significant positive effect on antioxidant.