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Jingsong He,Ni Xie,Jianbo Yang,Hong Guan,Weicai Chen,Huisheng Wu,Zishan Yuan,Kun Wang,Guojin Li,Jie Sun,Limin Yu 한국유방암학회 2014 Journal of breast cancer Vol.17 No.3
Purpose: Synuclein-γ (SNCG), which was initially identified asbreast cancer specific gene 1, is highly expressed in advancedbreast cancers, but not in normal or benign breast tissue. Thisstudy aimed to evaluate the effects of SNCG siRNA-treatmenton breast cancer cells and elucidate the associated mechanisms. Methods: Vectors containing SNCG and negative control(NC) siRNAs were transfected into MDA-MB-231 cells; mRNAlevels were determined by real-time polymerase chain reaction. Cell proliferation was evaluated using the MTT assay, cell migrationwas assessed by the Transwell assay, apoptosis and cellcycle analyses were conducted with the flow cytometer, andWestern blot analysis was performed to determine the relativelevels of AKT, ERK, p-AKT, and p-ERK expression. Results:SNCG mRNA levels were significantly reduced in MDA-MB-231cells transfected with SNCG siRNA. Our results indicate that inSNCG siRNA-treated cells, cell migration and proliferation decreasedsignificantly, apoptosis was induced, and the cell cyclewas arrested. Western blot analysis indicated that the proteinlevels of p-AKT and p-ERK were much lower in the SNCG siRNA-treated groups, than in the control and NC groups. Conclusion:SNCG siRNA could decrease the migration and proliferationof breast cancer cells by downregulating the phosphorylationof AKT and ERK.
Research progress of triazine flame retardants
Jingsong Wang,Shouwu Yu,Shujuan Xiao 한국고분자학회 2023 Macromolecular Research Vol.31 No.4
With the concept of environmental protection deeply rooted in the hearts of the people, people pay more attention to the development of environmentally friendly flame retardants. Triazine flame retardants, which are environmentally friendly, have good compatibility with polymer matrix and strong molecular designability, have attracted extensive attention. In this paper, the general strategies for synthesizing small molecule triazine flame retardants, linear triazine flame retardants and hyperbranched triazine flame retardants are introduced, and the synthesis principle and application effect are emphasized. The development direction of triazine-based flame retardants in the future is also prospected.
Direct Observation of Radiative Flux in the Southern Yellow Sea
Lu, Lian-Gang,Yu, Fei,Diao, Xinyuan,Guo, Jingsong,Wang, Huiwu,Wei, Chuanjie The Korean Society of Oceanography 2008 Ocean science journal Vol.43 No.2
Direct measurements of four radiative components at air-sea boundary layer were conducted in the southern Yellow Sea during three cruises (seasons) in 2007. Simultaneous observations of meteorological (cloud cover, air temperature and humidity) and oceanographic (sea surface temperature) parameters were carried out. Observational results of radiative fluxes and meteorological and oceanographic parameters are presented. Mean diurnal cycles of four radiative components, net radiation, and sea surface albedo are calculated to achieve averages in different seasons. Net radiative fluxes in three seasons (winter, spring, autumn) are 8, 146, $60\;W/m^2$, respectively. Comparisons between the observed radiative fluxes and those estimated with formulas are taken.
Ultrathin Planar Graphene Supercapacitors
Yoo, Jung Joon,Balakrishnan, Kaushik,Huang, Jingsong,Meunier, Vincent,Sumpter, Bobby G.,Srivastava, Anchal,Conway, Michelle,Mohana Reddy, Arava Leela,Yu, Jin,Vajtai, Robert,Ajayan, Pulickel M. American Chemical Society 2011 Nano letters Vol.11 No.4
<P>With the advent of atomically thin and flat layers of conducting materials such as graphene, new designs for thin film energy storage devices with good performance have become possible. Here, we report an “in-plane” fabrication approach for ultrathin supercapacitors based on electrodes comprised of pristine graphene and multilayer reduced graphene oxide. The in-plane design is straightforward to implement and exploits efficiently the surface of each graphene layer for energy storage. The open architecture and the effect of graphene edges enable even the thinnest of devices, made from as grown 1−2 graphene layers, to reach specific capacities up to 80 μFcm<SUP>−2</SUP>, while much higher (394 μFcm<SUP>−2</SUP>) specific capacities are observed multilayer reduced graphene oxide electrodes. The performances of devices with pristine as well as thicker graphene-based structures are examined using a combination of experiments and model calculations. The demonstrated all solid-state supercapacitors provide a prototype for a broad range of thin-film based energy storage devices.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/nalefd/2011/nalefd.2011.11.issue-4/nl200225j/production/images/medium/nl-2011-00225j_0001.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/nl200225j'>ACS Electronic Supporting Info</A></P>
Progress and challenges in full spectrum photocatalysts: Mechanism and photocatalytic applications
Jinghang Xu,Jun Shen,Haopeng Jiang,Xiaohui Yu,Waqar Ahmad Qureshi,Chanez Maouche,Jingsong Gao,Juan Yang,Qinqin Liu 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.119 No.-
How to efficiently convert solar energy into storable chemical energy has always been an urgent problemin the field of semiconductor-based photocatalysis. Broaden the light-absorption range of photocatalystsis an important strategy to improve the efficiency of solar energy conversion. This paper focused on therecent reported photocatalytic systems that can make use of full spectrum solar energy, and comparativelyexpounded their design, fabrication methods, mechanism and applications (H2 generation, CO2reduction, chemical synthesis and sterilization). Emphases were given to the specific mechanisms forfull-spectrum absorption in various photocatalysts, including semiconductors with narrow bandgaps,defective semiconductors, plasmonic nano-materials. The outlook was put forward that the future ofphotocatalytic research is infinite, and ongoing efforts should be devoted on the utilization of infraredlightpart in solar spectrum.
Masahiro Inoue,Hisamitsu Ide,Koji Kurihara,Tatsuro Koseki,Jingsong Yu,Toshiyuki China,Keisuke Saito,Shuji Isotani,Satoru Muto,Shigeo Horie 대한비뇨의학회 2012 Investigative and Clinical Urology Vol.53 No.6
Purpose: The purpose of this study was to investigate the clinical and hormonal features of patients with incidentally discovered adrenal adenomas in relation to corticotropin releasing hormone (CRH) testing and the clinical outcome of adrenalectomy. Materials and Methods: Twenty-three consecutive patients with incidentally detected adrenal adenomas were included in this retrospective study. All the patients underwent abdominal computed tomography scans and hormonal assays, including assessment of circadian rhythms of plasma cortisol and corticotropin (adrenocorticotropic hormone, ACTH), a corticotropin stimulation test, and low-dose and high-dose dexamethasone tests. The patients were reevaluated at regular intervals (6, 12, and 24 months) for a median period of 24 months. Subclinical Cushing’s syndrome (SCS) was diagnosed in patients with subtle hypercortisolism who did not present clinical signs of Cushing’s syndrome. Results: We calculated the responsive index (peak value of ACTH in CRH test/baseline value of ACTH in CRH test). Of 23 patients, 6 had Cushing’s syndrome, 8 had SCS, and 9 had a non-functioning tumor. All patients underwent laparoscopic adrenalectomy. Several patients (5 of 6 with Cushing’s syndrome and 2 of 8 with SCS) required cortisol replacement therapy after surgery. The remaining patients required no hormonal replacement after surgery. Those who required hormone replacement had a responsive index of less than 1.2. Those who did not need hormone replacement therapy had a responsive index of more than 2.0. Conclusions: In our limited experience, the responsive index of the CRH test might be a valuable tool for predicting the need for cortisol replacement after surgery in patients with SCS. Purpose: The purpose of this study was to investigate the clinical and hormonal features of patients with incidentally discovered adrenal adenomas in relation to corticotropin releasing hormone (CRH) testing and the clinical outcome of adrenalectomy. Materials and Methods: Twenty-three consecutive patients with incidentally detected adrenal adenomas were included in this retrospective study. All the patients underwent abdominal computed tomography scans and hormonal assays, including assessment of circadian rhythms of plasma cortisol and corticotropin (adrenocorticotropic hormone, ACTH), a corticotropin stimulation test, and low-dose and high-dose dexamethasone tests. The patients were reevaluated at regular intervals (6, 12, and 24 months) for a median period of 24 months. Subclinical Cushing’s syndrome (SCS) was diagnosed in patients with subtle hypercortisolism who did not present clinical signs of Cushing’s syndrome. Results: We calculated the responsive index (peak value of ACTH in CRH test/baseline value of ACTH in CRH test). Of 23 patients, 6 had Cushing’s syndrome, 8 had SCS, and 9 had a non-functioning tumor. All patients underwent laparoscopic adrenalectomy. Several patients (5 of 6 with Cushing’s syndrome and 2 of 8 with SCS) required cortisol replacement therapy after surgery. The remaining patients required no hormonal replacement after surgery. Those who required hormone replacement had a responsive index of less than 1.2. Those who did not need hormone replacement therapy had a responsive index of more than 2.0. Conclusions: In our limited experience, the responsive index of the CRH test might be a valuable tool for predicting the need for cortisol replacement after surgery in patients with SCS.