Adaptive Sliding Mode Control with Enhanced Optimal Reaching Law for Boost Converter Based Hybrid Power Sources in Electric Vehicles

Wang, Bin,Wang, Chaohui,Hu, Qiao,Ma, Guangliang,Zhou, Jiahui The Korean Institute of Power Electronics 2019 JOURNAL OF POWER ELECTRONICS Vol.19 No.2

This paper proposes an adaptive sliding mode control (ASMC) strategy with an enhanced optimal reaching law (EORL) for the robust current tracking control of the boost converter based hybrid power source (HPS) in an electric vehicle (EV). A conventional ASMC strategy based on state observers and the hysteresis control method is used to realize the current tracking control for the boost converter based HPS. Then a novel enhanced exponential reaching law is proposed to improve the ASMC. Moreover, an enhanced exponential reaching law is optimized by particle swarm optimization. Finally, the adaptive control factor is redesigned based on the EORL. Simulations and experiments are established to validate the ASMC strategy with the EORL. Results show that the ASMC strategy with the EORL has an excellent current tracking control effect for the boost converter based HPS. When compared with the conventional ASMC strategy, the convergence time of the ASMC strategy with the EORL can be effectively improved. In EV applications, the ASMC strategy with the EORL can achieve robust current tracking control of the boost converter based HPS. It can guarantee the active and stable power distribution for boost converter based HPS.

Active Patchy Colloids with Shape-Tunable Dynamics

Wang, Zuochen,Wang, Zhisheng,Li, Jiahui,Cheung, Simon Tsz Hang,Tian, Changhao,Kim, Shin-Hyun,Yi, Gi-Ra,Ducrot, Etienne,Wang, Yufeng American Chemical Society 2019 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY - Vol.141 No.37

<P>Controlling the complex dynamics of active colloids-the autonomous locomotion of colloidal particles and their spontaneous assembly-is challenging yet crucial for creating functional, out-of-equilibrium colloidal systems potentially useful for nano- and micromachines. Herein, by introducing the synthesis of active “patchy” colloids of various low-symmetry shapes, we demonstrate that the dynamics of such systems can be precisely tuned. The low-symmetry patchy colloids are made in bulk via a cluster-encapsulation-dewetting method. They carry essential information encoded in their shapes (particle geometry, number, size, and configurations of surface patches, etc.) that programs their locomotive and assembling behaviors. Under AC electric field, we show that the velocity of particle propulsion and the ability to brake and steer can be modulated by having two asymmetrical patches with various bending angles. The assembly of monopatch particles leads to the formation of dynamic and reconfigurable structures such as spinners and “cooperative swimmers” depending on the particle’s aspect ratios. A particle with two patches of different sizes allows for “directional bonding”, a concept popular in static assemblies but rare in dynamic ones. With the capability to make tunable and complex shapes, we anticipate the discovery of a diverse range of new dynamics and structures when other external stimuli (e.g., magnetic, optical, chemical, etc.) are employed and spark synergy with shapes.</P> [FIG OMISSION]</BR>

Adaptive Sliding Mode Control with Enhanced Optimal Reaching Law for Boost Converter Based Hybrid Power Sources in Electric Vehicles

Bin Wang,Chaohui Wang,Qiao Hu,Guangliang Ma,Jiahui Zhou 전력전자학회 2019 JOURNAL OF POWER ELECTRONICS Vol.19 No.2

This paper proposes an adaptive sliding mode control (ASMC) strategy with an enhanced optimal reaching law (EORL) for the robust current tracking control of the boost converter based hybrid power source (HPS) in an electric vehicle (EV). A conventional ASMC strategy based on state observers and the hysteresis control method is used to realize the current tracking control for the boost converter based HPS. Then a novel enhanced exponential reaching law is proposed to improve the ASMC. Moreover, an enhanced exponential reaching law is optimized by particle swarm optimization. Finally, the adaptive control factor is redesigned based on the EORL. Simulations and experiments are established to validate the ASMC strategy with the EORL. Results show that the ASMC strategy with the EORL has an excellent current tracking control effect for the boost converter based HPS. When compared with the conventional ASMC strategy, the convergence time of the ASMC strategy with the EORL can be effectively improved. In EV applications, the ASMC strategy with the EORL can achieve robust current tracking control of the boost converter based HPS. It can guarantee the active and stable power distribution for boost converter based HPS.

20(S)-ginsenoside Rh2 ameliorates ATRA resistance in APL by modulating lactylation-driven METTL3

Siyu Cheng,Langqun Chen,Jiahui Ying,Ying Wang,Wenjuan Jiang,Qi Zhang,Hong Zhang,Jiahe Wang,Chen Wang,Huimin Wu,Jing Ye,Liang Zhang 고려인삼학회 2024 Journal of Ginseng Research Vol.48 No.3

Background: 20(S)-ginsenoside Rh2(GRh2), an effective natural histone deacetylase inhibitor, can inhibit acute myeloid leukemia (AML) cell proliferation. Lactate regulated histone lactylation, which has different temporal dynamics from acetylation. However, whether the high level of lactylation modification that we first detected in acute promyelocytic leukemia (APL) is associated with all-trans retinoic acid (ATRA) resistance has not been reported. Furthermore, Whether GRh2 can regulate lactylation modification in ATRA-resistant APL remains unknown. Methods: Lactylation and METTL3 expression levels in ATRA-sensitive and ATRA-resistant APL cells were detected by Western blot analysis, qRT-PCR and CO-IP. Flow cytometry (FCM) and APL xenograft mouse models were used to determine the effect of METTL3 and GRh2 on ATRA-resistance. Results: Histone lactylation and METTL3 expression levels were considerably upregulated in ATRA-resistant APL cells. METTL3 was regulated by histone lactylation and direct lactylation modification. Overexpression of METTL3 promoted ATRA-resistance. GRh2 ameliorated ATRA-resistance by downregulated lactylation level and directly inhibiting METTL3. Conclusions: This study suggests that lactylation-modified METTL3 could provide a promising strategy for ameliorating ATRA-resistance in APL, and GRh2 could act as a potential lactylation-modified METTL3 inhibitor to ameliorate ATRA-resistance in APL.

Protective Effect of Schisandra chinensis Polysaccharides Against the Immunological Liver Injury in Mice Based on Nrf2/ARE and TLR4/NF-κB Signaling Pathway

Yingying Shan,Bin Jiang,Jiahui Yu,Jiaye Wang,Xiaoli Wang,He Li,Chunmei Wang,JianGuang Chen,Jinghui Sun 한국식품영양과학회 2019 Journal of medicinal food Vol.22 No.9

We have previously demonstrated the hepatoprotective effect of Schisandra chinensis polysaccharides (SCP) against the liver injury induced by alcohol, high-fat diet, and carbon tetrachloride in mice. In this study, we investigated the effect of SCP against the immunological liver injury induced by concanavalin A (Con A) in mice. The results showed that SCP could significantly reduce the level of alanine aminotransferase (ALT), aspartate aminotransferase (AST), tumor necrosis factor-α (TNF-α), interferon-γ (IFN-γ), interleukin-1β (IL-1β), and interleukin-6 (IL-6) in the serum of mice with immunological liver injury. SCP could significantly decrease the content of malondialdehyde (MDA) and nitric oxide (NO) and increase the activity of superoxide dismutase (SOD) and glutathione (GSH) in the liver tissue. SCP could significantly increase the number of CD4+ and decrease the number of CD8+ in the peripheral blood, and elevate the ratio of CD4+/CD8+. SCP could significantly downregulate the expression of Kelch-like ECH-associated protein 1 (Keap1) and upregulate the expression of nuclear factor-erythroid 2-related factor2 (Nrf2) and downstream gene heme oxygenase-1 (HO-1), and downregulate the expression of toll-like receptor 4 (TLR4), myeloid differentiation primary response gene 88 (MyD88), and nuclear factor-kappa B (NF-κB) proteins. This study indicates that SCP can reduce the release of a large number of inflammatory factors to inhibit the oxidative stress in mice with the immunological liver injury induced by Con A, and its mechanism is closely related to the regulation of Nrf2/antioxidant response element and TLR4/NF-κB signaling pathways.

Magnetically separable attapulgite−TiO2−FexOy composites with superior activity towards photodegradation of methyl orange under visible light radiation

Jiahui Zhang,Lili Zhang,Shouyong Zhou,Haiqun Chen,Hui Zhong,Yijiang Zhao,Xin Wang 한국공업화학회 2014 Journal of Industrial and Engineering Chemistry Vol.20 No.5

A magnetically recoverable composite photocatalyst was obtained by introducing TiO2–FexOy hybrid oxide onto the surface of attapulgite via an in-situ deposit technique (marked as ATT–TiO2–FexOy-r, r represents molar ratio of r = nTi/(nTi + nFe)). The obtained composites were carefully characterized and results showed TiO2–FexOy particles with an average size of 10 nm were successfully loaded onto attapulgite fibers’ surface. The FexOy (mixture of Fe2O3 and Fe3O4) acted not only as magnetic source but also took part in the formation of TiO2–Fe2O3 heterojunction structure, which resulted in the obvious absorption in visible light region for the obtained ATT–TiO2–FexOy. The obtained ATT–TiO2–FexOy-r exhibited quite good catalytic activity towards photodegradation of methyl orange under visible light irradiation. The highest degradation ratio and COD removal of methyl orange reached to 94.13% and 90.91% for ATT–TiO2–FexOy-0.5. Moreover, ATT–TiO2–FexOy could be readily recovered and the degradation ratio maintains 83.89% after 5 cycles. Possible mechanism for this enhancement was proposed.

Multifunctional nanozyme‑reinforced copper‑coordination polymer nanoparticles for drug‑resistance bacteria extinction and diabetic wound healing

Jiahui Zhao,Tengfei Xu,Jichao Sun,Haitao Yuan,Mengyun Hou,Zhijie Li,Jigang Wang,Zhen Liang 한국생체재료학회 2023 생체재료학회지 Vol.27 No.00

Background Drug-resistant bacterial infections in chronic wounds are a persistent issue, as they are resistant to antibiotics and can cause excessive inflammation due to generation of reactive oxygen species (ROS). An effective solution would be to not only combat bacterial infections but also scavenge ROS to relieve inflammation at the wound site. Scaffolds with antioxidant properties are attractive for their ability to scavenge ROS, and there is medical demand in developing antioxidant enzyme-mimicking nanomaterials for wound healing. Methods In this study, we fabricated copper-coordination polymer nanoparticles (Cu-CPNs) through a self-assembly process. Furthermore, ε-polylysine (EPL), an antibacterial and cationic polymer, was integrated into the Cu-CPNs structure through a simple one-pot self-assembly process without sacrificing the glutathione peroxidase (GPx) and superoxide dismutase (SOD)-mimicking activity of Cu-CPNs. Results The resulting Cu-CPNs exhibit excellent antioxidant propertiesin mimicking the activity of glutathione peroxidase and superoxide dismutase and allowing them to effectively scavenge harmful ROS produced in wound sites. The in vitro experiments showed that the resulting Cu-CPNs@EPL complex have superior antioxidant properties and antibacterial effects. Bacterial metabolic analysis revealed that the complex mainly affects the cell membrane integrity and nucleic acid synthesis that leads to bacterial death. Conclusions The Cu-CPNs@EPL complex has impressive antioxidant properties and antibacterial effects, making it a promising solution for treating drug-resistant bacterial infections in chronic wounds. The complex’s ability to neutralize multiple ROS and reduce ROS-induced inflammation can help relieve inflammation at the wound site.

3D Bioprinted GelMA/PEGDA Hybrid Scaffold for Establishing an In Vitro Model of Melanoma

( Jiahui Duan ),( Yanyan Cao ),( Zhizhong Shen ),( Yongqiang Cheng ),( Zhuwei Ma ),( Lijing Wang ),( Yating Zhang ),( Yuchuan An ),( Shengbo Sang ) 한국미생물생명공학회 2022 Journal of microbiology and biotechnology Vol.32 No.4

Due to the high incidence of malignant melanoma, the establishment of in vitro models that recapitulate the tumor microenvironment is of great biological and clinical importance for tumor treatment and drug research. In this study, 3D printing technology was used to prepare GelMA/PEGDA composite scaffolds that mimic the microenvironment of human malignant melanoma cell (A375) growth and construct in vitro melanoma micro-models. The GelMA/PEGDA hybrid scaffold was tested by the mechanical property, cell live/dead assay, cell proliferation assay, cytoskeleton staining and drug loading assay. The growth of tumor cells in two- and three-dimensional culture systems and the anti-cancer effect of luteolin were evaluated using the live/dead staining method and the Cell Counting Kit-8 (CCK-8) method. The results showed a high aggregation of tumor cells on the 3D scaffold, which was suitable for long-term culture. Cytoskeleton staining and immunofluorescent protein staining were used to evaluate the degree of differentiation of tumor cells under 2D and 3D culture systems. The results indicated that 3D bioprinted scaffolds were more suitable for tumor cell expansion and differentiation, and the tumor cells were more aggressive. In addition, luteolin was time- and dose-dependent on tumor cells, and tumor cells in the 3D culture system were more resistant to the drug.

The evolution of radiation-induced point defects near symmetrical tilt Σ5 (310) <001> grain boundary in pure δ-plutonium: A molecular dynamics study

Wang, Yangzhong,Liu, Wenbo,Zhang, Jiahui,Yun, Di,Chen, Piheng Korean Nuclear Society 2021 Nuclear Engineering and Technology Vol.53 No.5

The effects of the symmetrical tilt Σ5 (310) <001> grain boundary (GB) on the evolution of radiation-induced point defects in pure δ-plutonium (Pu) were studied by Molecular dynamics (MD) simulations. The evolution of radiation-induced point defects was obtained when primary knock-on atom (PKA) was respectively set as -15 Å and 15 Å far from the GB and the number of residual defects was obtained as the distance from PKA to GB was changed. According to the results, compared with vacancies, interstitial atoms were more easily absorbed by GB. In addition, the formation energy of point defects was also calculated. The results showed that there was almost no difference for the formation energy of vacancies in the all matrix. However, the formation energy of interstitial atoms close to the GB was lower than that in the other bulk regions.

Twin Deterministic Policy Gradient Adaptive Dynamic Programming for Optimal Control of Affine Nonlinear Discrete-time Systems

Jiahui Xu,Jingcheng Wang,Jun Rao,Yanjiu Zhong,Shangwei Zhao 제어·로봇·시스템학회 2022 International Journal of Control, Automation, and Vol.20 No.9

Recent achievements in the field of adaptive dynamic programming (ADP), as well as the data resources and computational capabilities in modern control systems, have led to a growing interest in learning and data-driven control technologies. This paper proposes a twin deterministic policy gradient adaptive dynamic programming (TDPGADP) algorithm to solve the optimal control problem for a discrete-time affine nonlinear system in a modelfree scenario. To solve the overestimation problem resulted from function approximation errors, the minimum value between the double Q network is taken to update the control policy. The convergence of the proposed algorithm in which the value function is served as the Lyapunov function is verified. By designing a twin actor-critic network structure, combining the target network and a specially designed adaptive experience replay mechanism, the algorithm is convenient to implement and the sample efficiency of the learning process can be improved. Two simulation examples are conducted to verify the efficacy of the proposed method.