Who Consumes Political News through YouTube?: An Application of the OMA Framework to YouTube Use in South Korea

JeongHun Han(JeongHun Han) 한국학술연구원 2022 Korea Observer Vol.53 No.4

This study analyzes how individual motivations including political interest and media trust and cognitive abilities affect news consumption through YouTube in a high choice media environment of South Korea. In the empirical analysis, we use a nationally representative dataset differentiating respondents in tree types of users concerning YouTube - namely, non-users, non-news consumers, and news consumers. Applying a binary response model with sample selection, we resolve a potential selectin bias and prove that political interest is the strongest motivation leading individuals to consume news through YouTube. In addition, the positive impact of political interest is shown to increases as individuals trust less traditional news media. However, we do not find any evidence that news consumption through YouTube is biased toward a specific party or ideological orientation.

Bureaucratic and Legislative Characteristics in the Representation of the International Marriage Migrant Women in Korea

Han Jeonghun(한정훈) 21세기정치학회 2013 21세기 정치학회보 Vol.23 No.1

This article examines the bureaucratic and legislative characteristics in the representation of the International Marriage Migrant Women (IMMW) in Korea. Three theoretical hypotheses are developed from the consideration of institutional effectiveness, political parties' issue ownership and legislative bureaucratic collaboration. Empirical Results show first that the fragmentation and overlaps of bureaucratic authorities over the issues of the IMMW tends to limit the effectiveness of policy implementation. Second, IMMW issues are not owned by the members of a specific political party. Finally, the representation of the IMMW in Korea is more likely to be led by the bureaucratic agencies located at the lower level of bureaucratic hierarchy through the legislative collaboration with the governing party legislators.

Responding to Public

Han JeongHun 한국국제정치학회 2007 國際政治論叢 Vol.47 No.5

Rapid emergence and mechanisms of resistance by U87 glioblastoma cells to doxorubicin in an in vitro tumor microfluidic ecology

Han, Jeonghun,Jun, Yukyung,Kim, So Hyun,Hoang, Hong-Hoa,Jung, Yeonjoo,Kim, Suyeon,Kim, Jaesang,Austin, Robert H.,Lee, Sanghyuk,Park, Sungsu National Academy of Sciences 2016 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF Vol.113 No.50

<P>In vitro prediction of the probable rapid emergence of resistance to a drug in tumors could act to winnow out potential candidates for further costly development. We have developed a microfluidic device consisting of similar to 500 hexagonal microcompartments that provides a complex ecology with wide ranges of drug and nutrient gradients and local populations. This ecology of a fragmented metapopulation induced the drug resistance in stage IV U87 glioblastoma cells to doxorubicin in 7 d. Exome and transcriptome sequencing of the resistant cells identified mutations and differentially expressed genes. Gene ontology and pathway analyses of the genes identified showed that they were functionally relevant to the established mechanisms of doxorubicin action. Specifically, we identified (i) a frame-shift insertion in the filamin-A gene, which regulates the influx and efflux of topoisomerase II poisons; (ii) the overexpression of aldo-keto reductase enzymes, which convert doxorubicin into doxorubicinol; and (iii) activation of NF-kappa B via alterations in the nucleotide-binding oligomerization domain (NOD)-like receptor signaling pathway from mutations in three genes (CARD6, NSD1, and NLRP13) and the overexpression of inflammatory cytokines. Functional experiments support the in silico analyses and, together, demonstrate the effects of these genetic changes. Our findings suggest that, given the rapid evolution of resistance and the focused response, this technology could act as a rapid screening modality for genetic aberrations leading to resistance to chemotherapy as well as counter selection of drugs unlikely to be successful ultimately.</P>

[Free Paper] Effect of Berberine on p53 Expression by TPA in Breast Cancer Cells

Jeonghun Han,Sangmin Kim,Nam-Young Kim,Se Kyung Lee,Min-Young Choi,Jeonghui Lee,Jiyoung Kim,Seungpil Jung,Jee Soo Kim,Jung-Han Kim,Jun-Ho Choe,Jeong Eon Lee,Seok Jin Nam 대한외과학회 2011 대한외과학회 학술대회 초록집 Vol.2011 No.11

Recapitulation of cancer stem cell niches in glioblastoma on 3D microfluidic cell culture devices under gravity-driven perfusion

Han, Jeonghun,Oh, Seunghan,Hoang, Hong-Hoa,Nguyen, Dao Thi Thuy,Lim, Wanyoung,Shin, Tae Hwan,Lee, Gwang,Park, Sungsu THE KOREAN SOCIETY OF INDUSTRIAL AND ENGINEERING 2018 JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY -S Vol.62 No.-

<P><B>Abstract</B></P> <P>The low survival rate of patients with glioblastoma is in part due to the heterogeneity in the cell population of glioblastoma that includes cancer stem cells (CSCs). CSC niches include a hypoxic core that is also closely linked to self-renewal ability, migration, and drug resistance. Here, we report a CSC culture method in three-dimensional microfluidic cell culture devices under gravity-driven perfusion, which we dub hypoxia chips (H-chips). In H-chips, glioblastoma cells, U87, spontaneously formed spheroids within 12h, even without any addition of growth factors. Compared to monolayer-cultured cells in dishes, spheroids in H-chips showed higher expression of CSC markers, such as hypoxia-inducible factor-1α (HIF-1α), CD133, and nestin. Spheroids in H-chips were more resistant to doxorubicin than monolayer-cultured ones in dishes. Transcriptional profiling revealed that the expression of interleukin-6 (IL-6), one of the inflammatory cytokines, was higher in spheroids in H-chips than in monolayer-cultured cells in dishes. IL-6 depleted cells failed to form spheroids in H-chips, and their drug resistance decreased. These results suggest that in H-chips, glioblastoma cells increased the production of IL-6, and promoted spheroid formation and other cancer stem cell properties, such as drug resistance. Our microfluidic cell culture method is highly useful for recapitulating CSC niches.</P>

Validity and Reliability of Cognitive Assessment Using Virtual Environment Technology in Patients with Stroke

Ku, Jeonghun,Lee, Jang Han,Han, Kiwan,Kim, Sun I.,Kang, Youn Joo,Park, Eun Sook Wolters Kluwer Health, Inc. All rights reserved. 2009 AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITA Vol.88 No.9

Ku J, Lee JH, Han K, Kim SI, Kang YJ, Park ES: Validity and reliability of cognitive assessment using virtual environment technology in patients with stroke. OBJECTIVES:: We assessed the validity and reliability of a virtual environment technology (VET)-based cognitive assessment program that was developed as a measurement tool of cognitive abilities in patients after a stroke. DESIGN:: Twenty participants diagnosed with stroke caused by unilateral brain lesions were enrolled to assess the VET program’s validity and test-retest reliability. Participants underwent evaluation by paper-based neuropsychological tests including the Korean Mini-Mental Status Examination, the Korean-Wechsler Adult Intelligence Scale, the Motor Free Visual Perception Test, Rey-Kim Memory Test, and Kim’s Frontal-Executive Neuropsychologic Test as well as the VET-based cognitive assessment. Major variables and indices of the VET program were calculated. The VET program validity was evaluated using a simple correlation analysis between variables from the VET program and conventional paper-based neuropsychological measurements, and the reliability was evaluated by investigating the test-retest correlation coefficients. RESULTS:: Major variables and indices of the VET program in patients with stroke correlated significantly with the related scores of paper-based neuropsychological tests. In addition, the test-retest reliability analysis revealed that the correlation coefficients ranged from 0.528 to 0.926. CONCLUSION:: The VET-based cognitive assessment program showed adequate reliability and validity as a method of cognitive assessment in patients after stroke.

고려시대 강진지역 교통입지와 청자 유통

한정훈(Han, Jeonghun) 연세대학교 강진다산실학연구원 2016 다산과현대 Vol.9 No.-

The study examined land and water transportation networks in Gangjin area and transportation of Gangjin celadon porcelain through the transportation networks. Land and water transportation networks in Gangjin area were blocked by ‘MyeongRyangHang(鳴梁項)’ which is tough place in the sea and mountain areas in Wolchool(月出) mountain. So for sea route, besides Tamjin(耽津) and Mipo (彌浦) in Gangjin bay, Jodongpo(潮東浦) in Yeongam was actively used as an alternative harbor to avoid MyeongRyangHang(鳴梁項). In existing studies, it was understood that nearby Jangheungchang(長興倉) warehouse, one of Jochang(漕倉) is a main transit for transportation of Gangjin celadon porcelain and transportation activity actively used personal and physical basis of Jochang warehouse. But in the aspect of transportation history, it was identified that ship for Gangjin celadon porcelain for tribute started at Jochang warehouse and maybe could start in Mipo(彌浦) near Daeguso(大口所) as well. For Gangjin celadon porcelain, characteristic of celadon porcelain and transportation volume became main elements to decide departure place. Like Taean ship(태안선), large cargo of celadon porcelain preferred Mipo though burden to pass through MyeongRyangHang. Like Mado ship No.1(마도1호선), small cargo of celadon porcelain started in Jodongpo in Yeongam over uphill pass. Thus, at the Daeguso(大口所) which was the largest producer of celadon porcelain in Goryeo, using work force of Bugokmin(部曲民), Gangjin celadon porcelain was transported at not only Jochang warehouse but also Mipo. This is a unique characteristic of Gangjin Daeguso(大口所) different from Buan area which is another production place of celadon porcelain.

제6회 지방선거의 투표율과 후보자들의 정책공약

한정훈(HAN Jeonghun) 한국정치학회 2014 한국정치학회보 Vol.48 No.5

본 연구는 기초단체장 선거구별로 지방선거 후보자들의 선거공약적 특성이 투표율에 미치는 영향력을 분석한다. 특히 제6회 지방선거의 서울경기지역 56개 선거구를 대상으로 후보자들이 선거공약을 통해 동일정당 후보와의 정책적 연합을 꾀하는 강도와 경쟁정당 후보와의 정책적 대결의 강도에 따른 투표율의 변화를 분석한다. 이를 위해 각 후보자의 선거공보에 대한 내용분석을 시도하고, 그 결과물을 활용하여 선거구별 후보자 간 선거공약이 공유되는 정도를 측정한다. 분석결과는 각 선거구의 후보자들이 동일정당에 소속된 광역단체장 후보와 선거공약을 공유하는 강도가 높을수록 해당 선거구의 투표율이 하락하는 경향을 보여준다. 반면, 각 선거구에서 경쟁하는 후보들이 선거공약을 공유하는 강도가 높을수록 투표율이 상승하는 경향이 관찰되었다. 본 연구 결과는 한국 선거분석에서 미진한 후보자의 정책과 투표율의 연관성에 대한 논의를 보강하는 의미를 지닌다. This article analyzes the effect of electoral commitments on turnout rates at 56 districts of Seoul and Gyeonggi province in the 2014 Korean local elections. After conducting a content analysis with election campaign booklets of each candidate, it develops the empirical indicators measuring respectively the levels of similarity of policy commitments at each district resulting from two different candidate"s strategies: using similar policy commitments with her party member who competes at the higher level of electoral district and competing at her district with distinct policy commitments from her competitors. Empirical analysis shows that as candidates in a district are more likely to share policy commitments with her party member competing at the higher level of electoral district, turnout rate of the district is likely to be lower. In contrast, the more policy commitments are shared between competitors at a district, the higher the turnout rate is. These findings would extend our understandings of the relationship between turnout and policy commitment at Korean elections.

유권자와 정당의 연계성(linkage)

한정훈(Jeonghun Han) 명지대학교 미래정치연구소 2013 미래정치연구 Vol.3 No.1

본 연구는 지역과 정당과의 피상적 연계성이 약화되면서 나타난 한국 정당정치의 위기에 대응하여 한국 정당들이 유권자와의 연계성을 강화할 수 있는 방안을 모색하고자 한다. 이를 위해 초국적 정당인 유럽사회당의 유럽의회 내 원내정당이라 할 수 있는 유럽진보연합에 대한 문헌 자료 수집과 기술적 사례분석을 시도하였다. 특히 1979년 이후 유럽사회당의 메니페스토 및 상징물의 변화를 분석하였다. 연구결과는 유럽통합 초기부터 유럽사회당의 회원국 정당들 간 정책 공조의 노력은 유권자에게 지속적으로 일관된 정책적 입장을 전달해 왔음을 보여준다. 이러한 정책적 일관성은 유럽사회당의 유럽의회 내 원내정당이라 할 수 있는 유럽진보연합의 득표율 및 유럽연합 회원국들의 투표율의 안정성과 일정 정도 연관성이 있음이 드러났다. This article explores a way of improving the linkage between Korean voters and parties in response to the current crisis of party politics in Korea. In so doing, it performs a descriptive analysis of the policy consistency at the Party of the European Socialists(PES), a part of whose members consists of the Progressive Alliance of Socialists and Democrats (S&D) in the European Parliament. Results from the analysis of the party’s official documents such as party manifestoes show that the arty has made enduring efforts to deliver consistent policy positions to their supporters in Europe. In addition, high turnout rates in the European elections among the old member states and low rates of defection from party support show that the policy consistency of the party may help to develop a stable party support among European voters.