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Comprehensive Analysis of Blood Culture Performed at Nine University Hospitals in Korea
Shin, Jeong Hwan,Song, Sae Am,Kim, Mi-Na,Lee, Nam Yong,Kim, Eui-Chong,Kim, Sunjoo,Koo, Sun-Hoi,Ryoo, Nam Hee,Kim, Jae-Seok,Cho, Ji-Hyun The Korean Society for Laboratory Medicine 2011 Annals of Laboratory Medicine Vol.31 No.2
<P><B>Background</B></P><P>Optimal blood culture performance is critical for successful diagnosis and treatment of sepsis. To understand the status of blood culture, we investigated several aspects of the procedure at 9 university hospitals.</P><P><B>Methods</B></P><P>The process of ordering blood culture sets and sampling volume for adults and children was investigated from January 2010 to April 2010, while the positive rate of detection and growth of skin contaminants were compared in 2009. Microbial growth in aerobic and anaerobic bottles was investigated prospectively.</P><P><B>Results</B></P><P>A majority of the hospitals used 2 sets of bottles for adults and 1 bottle for children. The average blood volume in each set was 7.7 mL for adults and 2.1 mL for children. The positive rate of microorganisms was 8.0%, and the isolation rate of the normal flora of the skin was 2.1%. Bacterial growth rates in aerobic and anaerobic bottles only were 31.8% and 24.5% respectively.</P><P><B>Conclusions</B></P><P>Ordering blood culture sets and sampling volumes did not comply with CLSI guidelines. However, the rate of positive cultures and skin contamination rates were acceptable. Anaerobic bottles are useful in enhancing the yield of microorganisms.</P>
A new mid-late maturing japonica rice variety Hyeonpum with a good grain quality and eating quality
Jeong-Ju Kim,Woon-Chul Shin,Mun-Sik Shin,Ki-Yeong Kim,Bo-Kyeong Kim,Jeong-Kwon Nam,Jong-Cheol Ko,Hyeon-Su Park,Ki-Yong Ha,Man-Kee Baek,So-Hyeon Baek,Young-Jun Mo,Woo-Jae Kim,Hyeon-Jung Kang,Jae-Kwon K 한국육종학회 2013 한국육종학회 심포지엄 Vol.2013 No.07
‘Hyeonpum’ is a new japonica rice variety developed by a cross breeding between Iksan469 having a good canopy architecture and Sindongjin and Musashino 7 having a good eating-quality with a view to develop a new variety having high quality of grain and palatability by the rice breeding team of Rice Breeding and Cultivation Research Division, Department of Rice and Winter Cereal Crop, NICS, RDA in 2012. The heading date of this variety is August 18 and later than that of check variety, Nampyeongbyeo, by four days. ‘Hyeonpum’ has 74cm of culm length and 101 spikelets per panicle. This variety showed resistance to bacterial leaf blight and rice stripe virus, but susceptible to leaf blast and planthoppers. The milled rice of this variety exhibits translucent and very clear non-glutinous endosperm. ‘Hyeonpum’ has much better palatability of cooked rice than that of Nampyeongbyeo. The whole grain rate of milled rice and milled rice recovery of ‘Hyeonpum’ are slightly higher than those of Nampyeongbyeo as 91.8% and 75.2% respectively. The yield of ‘Hyeonpum’ is 5.6 MT/ha in milled rice. ‘Hyeonpum’ could be adaptable to the southern part plain area of Pyeongtaek and southwestern costal areas in Korea.
Serotonin Inhibits Osteoblast Differentiation and Bone Regeneration in Rats
Nam, Soon-Shin,Lee, Jeong Cheol,Kim, Hyo Jeong,Park, Jin-Woo,Lee, Jae-Mok,Suh, Jo-Young,Um, Heung-Sik,Kim, Jae-Young,Lee, Youngkyun,Kim, Yong-Gun American Academy of Periodontology 2016 Journal of periodontology Vol.87 No.4
<P>Background: Although increasing evidence indicates that serotonin (SER; 5-hydroxytrypamine [5-HT]) is involved in the regulation of bone metabolism, conflicting data exist regarding whether SER promotes or inhibits osteoblast differentiation and bone formation. Regeneration of functional bone is required for proper osseointegration of dental implants. Noticeably, the use of selective SER reuptake inhibitors was recently associated with the failure of osseointegrated dental implants. The present study examines the direct role of peripheral SER on the regulation of bone regeneration. Methods: The effect of SER on osteoblast differentiation and bone regeneration was examined using rat calvarial cell cultures in vitro and a rat critical-sized calvarial defect model in vivo. Results: Rat calvarial cells expressed SER receptors Htr1 (5HT1) and Htr2 (5-HT2), which are known to transmit signals in bone cells. In vitro, SER significantly reduced osteogenic differentiation and mineralization of rat calvarial cells with concomitant reduction of osteoblast marker genes including alkaline phosphatase (Alpl), osterix (Sp7), and osteocalcin (Bglap). Histologic and radiologic analyses using the rat critical-sized calvarial defect model revealed that the existence of SER significantly inhibited beta-phase tricalcium phosphate-induced bone regeneration. Conclusion: Results suggest that SER in the local bone microenvironment might play a negative role in osteoblast differentiation and bone formation in rats.</P>
Prevalence And Risk Factors For Atrial Fibrillation in the Elderly Korean Population
( Jung Nam Eun ),( Jeong Gwan Cho ),( Sung Soo Kim ),( Hyung Wook Park ),( Ki Hong Lee ),( Nam Sik Yoon ),( Yong Woon Yun ),( Min Ho Shin ),( Jun Ho Shin ) 대한내과학회 2015 대한내과학회 추계학술대회 Vol.2015 No.1
Background: Atrial fibrillation (AF) is the most common arrhythmia in elderly persons and associated with increased risk for thromboembolism and stroke. However, prevalence and risk factors for AF have not been known well in Korean population. Also, electrocardiographic (ECG) screening for AF in general population showed inconsistent results for reducing thromboembolism. We aimed to evaluate prevalence, risk factors for AF and benefit for ECG screening the elderly single cohort study. Methods: Consecutive 1,483 participants over 60 yr-old underwent ECG screening at the Bitgoel senior health town from March 2014.This cohort study include questionnaire for quality of life, physical examination, and further laboratory and echocardiographic findings in patients with AF. Multivariate analysis was performed to evaluate independent risk factors for AF. Benefit for ECG screening will be evaluated after 5-year completion of participants enrollment. Results: Prevalence of AF was 3.1% and increased with stepwise manner according to age group (1.0% vs. 3.3% vs. 7.2%, p<0.001). Patients with AF was elder, and more likely to be male, smoker and obese. Also, they had higher prevalence of diabetes mellitus and heart failure compared with patients without AF. Nearly half patients with AF (43.4 %) were newly detected via ECG screening. CHA2DS2-VASc and HAS-BLED score were not different between the patients with newly detected AF and already diagnosed AF. Anticoagulation was done 12 (26%) patients with CHA2DS2-VASc ≥2. Multivariable analysis demonstrated that AF was associated with increasing age (adjusted odds ratio [OR] 1.10, 95% confidence interval [CI] 1.04-1.16, p<0.001), male gender (adjusted OR 4.92, 95% CI 1.75-13.82, >p=0.002), obesity (BMI >25, adjusted OR 2.25, 95% CI 1.19-4.24, p=0.012) and heart failure (adjusted OR 7.28, 95% CI 1.17-45.24, p=0.033). Conclusions: The prevalence of AF was 3.1% in the elderly, which was much lower than western countries. Most of them were under-detected and under-treated in terms of anticoagulation. Further studies will determine that routine ECG screening might reduce the risk for thromboembolism in patients with AF.