원문 : 좌업 시간과 알코올 섭취가 30대 남자 사무직 근로자의 혈압과 혈관탄성에 미치는 영향

조봉오 ( Bong Oh Cho ),이인녕 ( In Yeong Lee ),정균근 ( Gyun Geun Jeong ),장창현 ( Chang Hyun Jang ) 한국운동생리학회(구 한국운동과학회) 2014 운동과학 Vol.23 No.3

조봉오, 이인녕, 정균근, 장창현. 좌업 시간과 알코올 섭취가 30대 남자 사무직 근로자의 혈압과 혈관탄성에 미치는 영향. 운동과학, 제23권 3호, 241-248, 2014. 본 연구의 목적은 일과 중 대부분을 좌업근무 형태로 업무를 수행하고, 스트레스로 인해 음주가 잦고, 운동이 부족한 30대 남자 사무직 음주자 15명을 대상으로 좌업 시간과 알코올 섭취가 혈압과 혈관탄성에 미치는 영향을 분석하여 사무직 근로자에게 건강관리에 필요한 정보를 제공하는데 있다. S대학 운동 생리학 실험실에서 사전 인적 사항과 설문을 작성하고, 신장, 체중, 채혈, 혈압, 혈관탄성, BMI를 측정하였다. 알코올 섭취 횟수, 섭취량, 좌업 시간, 그리고 음주 섭취 전과 후 및 시간대별 (10분, 40분, 60분) 혈압과 혈관탄성의 변화를 측정 분석한 결과를 요약하면 다음과 같다. 1) 평균 좌업시간이 9.87시간, 음주횟수 및 음주량은 월 평균 9.13회와 12.47잔 이였다. 2) 알코올 섭취횟수 및 섭취량에 따른 BMI, TC, LDL-C, HDL-C, 혈압과 혈관탄성 비교에서 알코올 섭취횟수에서 좌상지 혈관탄성은 통계적으로 유의한 차이를 나타냈다(p<.05). 3) 알코올 섭취 전, 후 비교 분석 결과 우상지와 좌상지의 혈관탄성에서 통계적으로 유의한 차이가 나타났다(p<.05). 4) 알코올 섭취 후 시간대별 우상지 혈관탄성은 통계적으로 유의한 차이를 나타냈다(p<.05). 이상의 결과를 종합해 볼 때, 좌업 시간이 혈압과 혈관탄성에 미치는 영향은 통계적으로 유의하게 나타나지 않았고, 알코올 섭취는 혈관탄성에 통계적으로 유의한 차이를 나타냄을 알 수 있었다. 따라서 이는 직장생활의 스트레스를 음주로 해소하는 경향이 있음을 보여주며 건강에 부정적인 영향을 주고 있음을 알 수 있었다. 또한, 신체가 음주에 적응되어 실험 시 섭취한 적은 양(1/2병)은 1회 12.47잔에 비해 혈압과 혈관탄성에 큰 영향을 미치지 못한 것으로 사료된다. Cho, Bong-Oh, Lee, In-Yeong, Jeong, Gyun-Geun, Jang, Chang-Hyun. Effects of Sedentary Occupation Time and Alcohol Intake on Blood Pressure and Vascular Compliance in 30s Male White-Collar Workers. Exercise Science, 23(3): 241-248. 2014. The purpose of this study was to examine effects of duration of sedentary office work and alcohol intake on blood pressure and vascular compliance in male subjects who were office workers aged between 30 to 39 and frequently drink alcoholic beverages to cope with their stress without exercising for health. The study was to provide health-related information necessary for white-collar workers. We collected data of demographic information, height, weight, blood sample, blood pressure, vascular compliance, and BMI from 15 subjects in S University`s Exercise Physiology Laboratory, and analyzed the frequency and amount of alcohol intake, duration of sedentary work, and changes in blood pressure and vascular compliance at diffident time points (10, 40, and 60 minutes post drinking) from baseline. I t was found that the average time of sedentary work was 9.87 hours, drinking 9.13 times a month on average, 12.47 glasses of alcohol beverages per drink. In comparison of BMI, TC, LDL-C, HDL-C, blood pressure and vascular compliance upon the frequency and amount of alcohol intake, the upper left limb`s vascular compliance had a statistically significant difference (p<.05). In the result of the comparative analysis of pre-and post-drinking, vascular compliance was significantly different in the upper right and left limbs (p<.05). Vascular compliance in the upper right limb after drinking significantly changed (p<.05). As a result, the duration of sedentary work had no statistically significant difference in blood pressure and vascular compliance. T he vascular compliance after drinking h ad a statistically significant difference. This suggested that the result was an index that shows the trend of the office workers releasing their work stress by drinking alcoholic beverages, and that drinking had negative impacts on them. In addition, a small amount of intake (a half bottle) at the test time, after the body was adjusted to drinking, compared with 12.47 glasses per intake, had no great impacts on blood pressure and vascular compliance.

방울토마토중 Dichlofluanid 및 Iprodione의 생산단계별 잔류농약 경시변화

최규일,성기용,정태균,이주환,허장현,고광용,이규승 한국환경농학회 2002 한국환경농학회지 Vol.21 No.4

방울토마토의 생산단계에서의 잔류허용기준 설정과 수확후 저장기간중 경시변화 및 세척에 의한 잔류농약의 감소양상을 파악하였다. 해당약제를 안전사용기준의 기준량 및 배량을 각각 시설재배 포장에서 살포후 10일간 잔류양상을 조사하였고, 실온 및 냉장조건 하에서의 저장실험 및 세척에 따른 전류농약의 잔소량을 파악하여 생산단계부터, 출하, 저장, 소비단계까지의 잔류량을 예측할 수 있는 모델개발을 위한 자료로 이용하고자 연구를 수행하였다. Dichlofluanid와 iprodione은 포장조건에서 반감일수가 기준량 2.2, 3.3일 이었으며, 배량은 3.5, 5.4일로 나타났다. 저장조건하에서의 약제별 반감기는 포장조건보다 잔류량의 감소속도가 느린 것으로 나타나 반감일수가 증가하였고, 세척방법에 의한 잔류농약의 감소량을 조사한 결과 세제 사용시의 평균제거율은 dichlofluanid는 73.7%, iprodione은 64.3%로 나타났고, tap-water 사용시에는 dichlofluanid 73.5%, iprodione 63.5%로 나타났다. 이러한 결과는 작물의 생산단계에서 구한 합리적인 희귀식을 이용하여 잔류농약의 경시변화를 파악하고, 저장 및 세척과정을 거쳐 최종 소비단계에서의 잔류농약의 수준을 평가할 수 있었다. We studied the residual patterns of two fungicides, dichlofluanid and iprodione, in cherry tomato greenhouse after applying with the recommended and double dose. Also, the degradation patterns during storage periods of up to ten days were compared between at room temperature (20℃) and at cold temperature (4℃). Removal rates of fungicides by washing with tap-water and detergent solution (0.1%, 0.2%) were measured. Half-lives of dichlofluanid and iprodione in greenhouse cherrytomato were 2.2~3.5 and 3.3~5.4 days, respectively. During the storage period, the residues were dissipated more slow. Removal rates were 62.8~80.3% by tap-water, 60.4~83.1% by 0.1% detergent solution, and 65.3~77.6% by 0.2% detergent solution. So, we can predict of terminal residues from cultivation period to marketing, storage and consuming.

Optimal Selection of Sedative Drug during Gastroduodenoscopy in Cirrhotic Patients to Avoid Minimal Encephalopathy: Interim-Analysis of Randomized Controlled Trial

( Jeong-ju Yoo ),( Hyeon Jeong Goong ),( Sang Gyune Kim ),( Young Seok Kim ),( Soung Won Jeong ),( Jae Young Jang ),( Sae Hwan Lee ),( Hong Soo Kim ),( Baek Gyu Jun ),( Young Don Kim ),( Gab Jin Cheon 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1

Aims: The indiscriminate use of sedative drug during endoscopy can pose a risk of minimal hepatic encephalopathy (MHE) in patient with liver cirrhosis, . However, it has not been studied yet which drugs are safest and most inviting on these patients. The aim of this study is to evaluate which one among midazolam, propofol, or combination therapy, was the least likely to cause complications including MHE by using Stroop application in cirrhotic patients. Methods: This randomized prospective study included consecutive 32 patients who underwent upper GI endoscopy at tertiary hospitals in Korea. Patients were randomly assigned to one of three groups, midazolam, propofol, or combination group, and underwent Stroop test before endoscopy, and 2 hours after the completion of endoscopy. The vital signs was checked before and after the drug administration and the patient / physician / nurse satisfaction was scored after endoscopy. Results: Mean age of the patients was 54.0 ± 9.30 years and 81.3% were male. Fifteen patients (46.9%) were child-pugh class A, and 17 (53.1%) were child-pugh class B or C. Alcohol was the most common etiology (21, 65.6%). Patients did not show significant changes in Ontime, Offtime on Stroop test before and after drug administration, and there was no significant difference between the three treatment groups. Also, there was no significant vital sign changes after drug use in all groups. However, with respect to subjective indicators, the satisfaction scores of patient and nursing staff was higher in the combined group than in the other two groups, and time to recovery was shorter in propofol than other groups. Conclusions: In patients with cirrhosis, sedative endoscopy using midazolam, propofol, or combination therapy is relatively safe, and was not associated with increased risk of MHE. However, since there is subjective satisfaction or recovery time difference among sedative agents, it should be considered according to each individual patient.

태양광 발전시스템의 그림자 영향을 고려한 능동형 모듈 개발

정학균(Hak-Gyun Jeong),고재섭(Jae-Sub Ko),이진국(Jin-Gook Lee),정다은(Da-Eun Jeong),장미금(Mi-Geum Jang),정동화(Dong-Hwa Chung) 한국조명·전기설비학회 2012 한국조명·전기설비학회 학술대회논문집 Vol.2012 No.5

Effect of rice hull biochar treatment on net ecosystem carbon budget and greenhouse gas emissions in Chinese cabbage cultivation on infertile soil

Park Do-Gyun,Jeong Hyeon-Cheol,Jang Eun-Bin,Lee Jong-Mun,Lee Hyoung-Seok,Park Hye-Ran,Lee Sun-Il,Park Do-Gyun,Jang Eun-Bin,Oh Taek-Keun 한국응용생명화학회 2024 Applied Biological Chemistry (Appl Biol Chem) Vol.67 No.-

Biochar, with its potential to enhance soil fertility, sequester carbon, boost crop yields and reduce greenhouse gas emissions, offers a solution. Addressing the challenges posed by climate change is crucial for food security and agriculture. However, its widespread adoption in agriculture remains in its infancy. This study assessed the effects of rice hull biochar on cabbage production and greenhouse gas emissions, especially nitrous oxide (N 2 O). A trial, employing a randomized block design in triplicate was conducted from September 13 to November 23, 2022, where "Cheongomabi" cabbage was cultivated with N-P 2 O 5 -K 2 O fertilization at 32 $$-$$ - 7.8 $$-$$ - 19.8 kg 10a −1 . Additional fertilizer was applied twice post-sowing. The Biochar application rates were control = 0 ton ha −1 , B1 = 1 ton ha −1 , B3 = 3 ton ha −1 , and B5 = 5 ton ha −1 . The aboveground biomass of autumn cabbage harvested 82 days after sowing was 2.40–2.70 kg plant −1 in the control and biochar treatments (B1, B3, and B5), with no significant differences ( p  > 0.05). Cumulative CO 2 emissions during cultivation varied across treatment groups, with initial and cumulative emissions of 10.40–17.94 g m −2  day −1 and 3.63–4.43 ton ha −1 , respectively. N 2 O emissions decreased with higher biochar application: reductions of 2.9%, 25.4%, and 41.1% in the B1, B3, and B5 treatments, respectively, compared to the control. The biochar application had no significant impact on yield but curbed soil emissions, Net ecosystem carbon balance during cabbage cultivation ranged from 0.42 to 3.41 ton ha −1 for the B1, B3, and B5 treatments, respectively, compared to control. Overall, the study underscores biochar’s role in mitigating emissions and boosting soil carbon during cabbage cultivation in fall. Biochar, with its potential to enhance soil fertility, sequester carbon, boost crop yields and reduce greenhouse gas emissions, offers a solution. Addressing the challenges posed by climate change is crucial for food security and agriculture. However, its widespread adoption in agriculture remains in its infancy. This study assessed the effects of rice hull biochar on cabbage production and greenhouse gas emissions, especially nitrous oxide ( N2O). A trial, employing a randomized block design in triplicate was conducted from September 13 to November 23, 2022, where "Cheongomabi" cabbage was cultivated with N-P2O5-K2O fertilization at 32−7.8−19.8 kg 10a− 1. Additional fertilizer was applied twice post-sowing. The Biochar application rates were control = 0 ton ha− 1, B1 = 1 ton ha− 1, B3 = 3 ton ha− 1, and B5 = 5 ton ha− 1. The aboveground biomass of autumn cabbage harvested 82 days after sowing was 2.40– 2.70 kg plant− 1 in the control and biochar treatments (B1, B3, and B5), with no significant differences (p > 0.05). Cumulative CO2 emissions during cultivation varied across treatment groups, with initial and cumulative emissions of 10.40–17.94 g m− 2 day− 1 and 3.63–4.43 ton ha− 1, respectively. N2O emissions decreased with higher biochar application: reductions of 2.9%, 25.4%, and 41.1% in the B1, B3, and B5 treatments, respectively, compared to the control. The biochar application had no significant impact on yield but curbed soil emissions, Net ecosystem carbon balance during cabbage cultivation ranged from 0.42 to 3.41 ton ha− 1 for the B1, B3, and B5 treatments, respectively, compared to control. Overall, the study underscores biochar’s role in mitigating emissions and boosting soil carbon during cabbage cultivation in fall.

Design and Analysis of Collimator in Spectrophotometer for Transmission Spectroscopy of Exoplanets

Yeonho Choi,Kang-Min Kim,Chan Park,Jeong-Gyun Jang,Inwoo Han,Byeong-Cheol Lee,Bi-Ho Jang,Jong-Ung Lee,Eui-Jeong Jeong,Myeong-Gu Park 한국천문학회 2020 天文學會報 Vol.45 No.1

Node-Positive Bladder Cancer After Neoadjuvant Chemotherapy Followed by Radical Cystectomy: A Single-Center Retrospective Study

Jang Ho Cho(조장호),Ghee-Young Kwon(권기영),Minyong Kang(강민용),Hyun Hwan Sung(성현환),Hwang Gyun Jeon(전황균),Byong Chang Jeong(정병창),Seong Il Seo(서성일),Seong Soo Jeon(전성수),Hyun Moo Lee(이현무),Han-Yong Choi(최한용),Su Ji 대한비뇨기종양학회 2020 대한비뇨기종양학회지 Vol.18 No.3

Purpose: There remains a lot of unmet need to increase understanding of node-positive (ypN+) muscle invasive bladder cancer (MIBC) after neoadjuvant chemotherapy and radical cystectomy to decide the appropriate therapeutics. Materials and Methods: In a retrospective study using the center cancer chemotherapy registry, we found 113 MIBC patients who were treated with neoadjuvant chemotherapy involving gemcitabine and cisplatin (GP) followed by radical cystectomy between 2010 and 2014. Disease-free survival (DFS) and overall survival (OS) were compared according to the pathologic node positivity (ypN- vs. ypN+). Among a total of 165 patients with MIBC who received neoadjuvant chemotherapy involving GP, 118 underwent radical cystectomy. In 46 patients with ypN+ disease, DFS and OS were evaluated according to administration of adjuvant GP. Results: After neoadjuvant chemotherapy and radical cystectomy, 41% of patients had ypN+ disease, which showed significantly shorter DFS (median, 7.4 months; 95% confidence interval [CI], 5.3–9.6 months) and OS (median, 20.0 months; 95% CI, 13.4–26.6 months) compared to those with ypN- disease. The patients with ypN+ disease had a high risk of recurrence or death, regardless of the administration of adjuvant chemotherapy or adjuvant regimen. Conclusions: Within the limitations of this retrospective study, MIBC patients with ypN+ disease despite neoadjuvant chemotherapy and radical cystectomy had a poor prognosis. Further studies involving novel, effective adjuvant treatment including immunotherapy agents are needed to reduce the high risk of recurrence or death in these patients.

Factors affecting bone mineral density in children and adolescents with secondary osteoporosis

Jang Min Jeong,Shin Chungwoo,Kim Seongkoo,Lee Jae Wook,Chung Nack-Gyun,Cho Bin,Jung Min Ho,Suh Byung-Kyu,Ahn Moon Bae 대한소아내분비학회 2023 Apem Vol.28 No.1

Purpose: This study aimed to investigate the clinical factors associated with bone mineral density (BMD) among children and adolescents with osteoporosis secondary to treatment for underlying clinical conditions.Methods: We retrospectively reviewed the medical records of patients aged 10–18 years and evaluated them for lumbar spine BMD (LSBMD) after treatment for underlying diseases, including hemato-oncologic, rheumatologic system, and inflammator y bowel diseases. LSBMD measured by dual-energy x-ray absorptiometry (DXA) performed from March 2019 to March 2021 was evaluated. We analyzed 117 patients who underwent initial DXA after treatment for underlying diseases.Results: Subjects in this study had multiple underlying diseases: hemato-oncologic (78.6%), rheumatologic (11.1%), and inflammatory bowel diseases (10.3%). There was no significant association between the z-score and bone metabolic markers (P>0.05). However, higher cumulative glucocorticoid (GC) dose significantly reduced LSBMD z-score (<i>P</i>=0.029). Moreover, the association between cumulative dose of GC and initial z-score of LSBMD was significant in logarithmic regression analysis (<i>P</i>=0.003, R²=0.149). GC accumulation was a significant risk factor for vertebral fracture when the initial BMD was evaluated after treatment (<i>P</i>=0.043). Bone metabolic markers did not significantly influence the risk of vertebral fracture.Conclusion: Initial bone mass density of the lumbar spine evaluated after long-term GC use for underlying diseases is a predictor of further vertebral fractures.

Size and Location of Ruptured Intracranial Aneurysms

Jeong, Young-Gyun,Jung, Yong-Tae,Kim, Moo-Seong,Eun, Choong-Ki,Jang, Sang-Hwan The Korean Neurosurgical Society 2009 Journal of Korean neurosurgical society Vol.45 No.1

Objective : The aim of study was to review our patient population to determine whether there is a critical aneurysm size at which the incidence of rupture increases and whether there is a correlation between aneurysm size and location. Methods : We reviewed charts and radiological findings (computed tomography (CT) scans, angiograms, CT angiography, magnetic resonance angiography) for all patients operated on for intracranial aneurysms in our hospital between September 2002 and May 2004. Of the 336 aneurysms that were reviewed, measurements were obtained from angiograms for 239 ruptured aneurysms by a neuroradiologist at the time of diagnosis in our hospital. Results : There were 115 male and 221 female patients assessed in this study. The locations of aneurysms were the middle cerebral artery (MCA, 61), anterior communicating artery (ACoA, 66), posterior communicating artery (PCoA, 52), the top of the basilar artery (15), internal carotid artery (ICA) including the cavernous portion (13), anterior choroidal artery (AChA, 7), A1 segment of the anterior cerebral artery (3), A2 segment of the anterior cerebral artery (11), posterior inferior cerebellar artery (PICA, 8), superior cerebellar artery (SCA, 2), P2 segment of the posterior cerebral artery (1), and the vertebral artery (2). The mean diameter of aneurysms was $5.47{\pm}2.536\;mm$ in anterior cerebral artery (ACA), $6.84{\pm}3.941\;mm$ in ICA, $7.09{\pm}3.652\;mm$ in MCA and $6.21{\pm}3.697\;mm$ in vertebrobasilar artery. The ACA aneurysms were smaller than the MCA aneurysms. Aneurysms less than 6 mm in diameter included 37 (60.65%) in patients with aneurysms in the MCA, 43 (65.15%) in patients with aneurysms in the ACoA and 29 (55.76%) in patients with aneurysms in the PCoA. Conclusion : Ruptured aneurysms in the ACA were smaller than those in the MCA. The most prevalent aneurysm size was 3-6 mm in the MCA (55.73%), 3-6 mm in the ACoA (57.57%) and 4-6 mm in the PCoA (42.30%). The more prevalent size of the aneurysm to treat may differ in accordance with the location of the aneurysm.

Clinical Significance of Relative Adrenal Insufficiency on the Development of Complications and Mortality in Patients with Liver Cirrhosis

( Jeong-ju Yoo ),( Sang Gyune Kim ),( Seong Joon Chun ),( Young Seok Kim ),( Young Chang ),( Soung Won Jeong ),( Jae Young Jang ),( Sae Hwan Lee ),( Hong Soo Kim ),( Baek Gyu Jun ),( Young Don Kim ),( 대한간학회 2020 춘·추계 학술대회 (KASL) Vol.2020 No.1

Aims: It is not yet known how much relative adrenal insufficiency (RAI) affects the prognosis of patients with liver cirrhosis. We evaluated the prevalence of RAI in hospitalized patients with liver cirrhosis, and examined their association with prognosis. Methods: This study included 297 consecutive cirrhosis patients who underwent rapid ACTH stimulation test. RAI was defined by a delta cortisol lower than 9 g/dL and/or a peak cortisol lower than 18 g/dL. Results: RAI was diagnosed in 183 patients (61.6%) of the 297 patients. The group in RAI (+) had older age, a higher rate with infection, and a deteriorated liver function than the group in RAI (-). In addition, the cause of death from infection was higher in RAI (+) group than RAI (-) group (26.8% vs. 11.8%). The presence of RAI increased significantly the risk of hepatic encephalopathy, acute kidney injury and 3-month mortality. The clinical effect of RAI was further enhanced in the subgroup with relatively higher muscle mass (> ~~)and lower white blood cell count group (< 10,000 μL). Conclusions: The presence of RAI is relatively frequent in cirrhotic patients with older age, poor liver function and infection In addition, RAI significantly affects the development of complications and the prognosis of liver cirrhosis.