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      • SCIESCOPUSKCI등재

        True Digestibility of Phosphorus in Different Resources of Feed Ingredients in Growing Pigs

        Wu, X.,Ruan, Z.,Zhang, Y.G.,Hou, Y.Q.,Yin, Y.L.,Li, T.J.,Huang, R.L.,Chu, W.Y.,Kong, X.F.,Gao, B.,Chen, L.X. Asian Australasian Association of Animal Productio 2008 Animal Bioscience Vol.21 No.1

        To determine the true digestible phosphorus (TDP) requirement of growing pigs, two experiments were designed with the experimental diets containing five true digestible P levels (0.16%, 0.20%, 0.23%, 0.26% and 0.39%) and the ratio of total calcium to true digestible P (TDP) kept at 2:1. In Experiment 1, five barrows (Duroc${\times}$Landrace${\times}$Yorkshire) with an average initial body weight of 27.9 kg were used in a $5{\times}5$ Latin-square design to evaluate the effect of different dietary P levels on the digestibility and output of P and nitrogen. In Experiment 2, sixty healthy growing pigs (Duroc${\times}$Landrace${\times}$Yorkshire) with an average body weight (BW) of 21.4 kg were assigned randomly to one of the five dietary treatments (12 pigs/diet), and were used to determine the true digestible phosphorus (TDP) requirement of growing pigs on the basis of growth performance and serum biochemical indices. The results indicated that the true digestibility of P increased (p<0.05) linearly with increasing dietary TDP level below 0.26%. The true P digestibility was highest (56.6%) when dietary TDP was 0.34%. Expressed as g/kg dry matter intake (DMI), fecal P output increased (p<0.05) linearly with increasing P input. On the basis of g/kg fecal dry matter (DM), fecal P output was lowest for Diet 4 and highest (p<0.05) for Diet 5. The apparent digestibility of crude protein (CP) did not differ (p>0.05) among the five diets, with the average nitrogen output of 12.14 g/d and nitrogen retention of 66% to 74% (p>0.05), which suggested that there was no interaction between dietary P and CP protein levels. During the 28-d experimental period of Experiment 2, the average daily gain (ADG) of pigs was affected by dietary TDP levels as described by Eq. (1): $y=-809,532x^4+788,079x^3-276,250x^2+42,114x-1,759$; ($R^2=0.99$; p<0.01; y = ADG, g/d; x = dietary TDP, %), F/G for pigs by Eq. (2): $y=3,651.1x^4-3,480.4x^3+1,183.8x^2-172.5x+10.9$ ($R^2=0.99$; p<0.01; y = F/G; x = dietary TDP, %), and Total P concentrations in serum by Eq. (3): $y=-3,311.7x^4+3,342.7x^3-1,224.6x^2+195.6x-8.7$ (R2 = 0.99; p<0.01; y = total serum P concentration and x = dietary TDP, %). The highest ADG (782 g/d), the lowest F/G (1.07) and the highest total serum P concentration (3.1 mmol/L) were obtained when dietary TDP level was 0.34%. Collectively, these results indicate that the optimal TDP requirement of growing pigs is 0.34% of the diet at a total Ca to TDP ratio of 2:1.

      • SCISCIESCOPUS

        The multiple merger assembly of a hyperluminous obscured quasar at redshift 4.6

        Dí,az-Santos, T.,Assef, R. J.,Blain, A. W.,Aravena, M.,Stern, D.,Tsai, C.-W.,Eisenhardt, P.,Wu, J.,Jun, H. D.,Dibert, K.,Inami, H.,Lansbury, G.,Leclercq, F. American Association for the Advancement of Scienc 2018 Science Vol.362 No.6418

        <P><B>Mergers drive a powerful dusty quasar</B></P><P>Massive galaxies in the early Universe host supermassive black holes at their centers. When material falls toward the black hole, it releases energy and is observed as a quasar. Astronomers found a population of powerful distant quasars that are obscured by dust, but it has been unclear how they are formed. Díaz-Santos <I>et al.</I> observed the dust-obscured quasar WISE J224607.56-052634.9 at submillimeter wavelengths, finding three small companion galaxies connected to the quasar by bridges of gas and dust. They inferred that galaxy mergers can provide both the raw material to power a quasar and large quantities of dust to obscure it.</P><P><I>Science</I>, this issue p. 1034</P><P>Galaxy mergers and gas accretion from the cosmic web drove the growth of galaxies and their central black holes at early epochs. We report spectroscopic imaging of a multiple merger event in the most luminous known galaxy, WISE J224607.56−052634.9 (W2246−0526), a dust-obscured quasar at redshift 4.6, 1.3 billion years after the Big Bang. Far-infrared dust continuum observations show three galaxy companions around W2246−0526 with disturbed morphologies, connected by streams of dust likely produced by the dynamical interaction. The detection of tidal dusty bridges shows that W2246−0526 is accreting its neighbors, suggesting that merger activity may be a dominant mechanism through which the most luminous galaxies simultaneously obscure and feed their central supermassive black holes.</P>

      • DISCOVERY OF X-RAY PULSATION FROM THE GEMINGA-LIKE PULSAR PSR J2021+4026

        Lin, L. C. C.,Hui, C. Y.,Hu, C. P.,Wu, J. H. K.,Huang, R. H. H.,Trepl, L.,Takata, J.,Seo, K. A.,Wang, Y.,Chou, Y.,Cheng, K. S. IOP Publishing 2013 ASTROPHYSICAL JOURNAL LETTERS - Vol.770 No.1

        <P>We report the discovery of an X-ray periodicity of similar to 265.3 ms from a deep XMM-Newton observation of the radio-quiet gamma-ray pulsar, PSR J2021+4026, located at the edge of the supernova remnant G78.2+2.1 (gamma-Cygni). The detected frequency is consistent with the gamma-ray pulsation determined by the observation of the Fermi Gamma-ray Space Telescope at the same epoch. The X-ray pulse profile resembles the modulation of a hot spot on the surface of the neutron star. The phase-averaged spectral analysis also suggests that the majority of the observed X-rays have thermal origins. This is the third member in the class of radio-quiet pulsars with significant pulsations detected from both X-ray and gamma-ray regimes.</P>

      • PANCHROMATIC OBSERVATIONS OF THE TEXTBOOK GRB 110205A: CONSTRAINING PHYSICAL MECHANISMS OF PROMPT EMISSION AND AFTERGLOW

        Zheng, W.,Shen, R. F.,Sakamoto, T.,Beardmore, A. P.,De Pasquale, M.,Wu, X. F.,Gorosabel, J.,Urata, Y.,Sugita, S.,Zhang, B.,Pozanenko, A.,Nissinen, M.,Sahu, D. K.,Im, M.,Ukwatta, T. N.,Andreev, M.,Klun IOP Publishing 2012 The Astrophysical journal Vol.751 No.2

        <P>We present a comprehensive analysis of a bright, long-duration (T-90 similar to 257 s) GRB 110205A at redshift z = 2.22. The optical prompt emission was detected by Swift/UVOT, ROTSE-IIIb, and BOOTES telescopes when the gamma-ray burst (GRB) was still radiating in the gamma-ray band, with optical light curve showing correlation with gamma-ray data. Nearly 200 s of observations were obtained simultaneously from optical, X-ray, to gamma-ray (1 eV to 5 MeV), which makes it one of the exceptional cases to study the broadband spectral energy distribution during the prompt emission phase. In particular, we clearly identify, for the first time, an interesting two-break energy spectrum, roughly consistent with the standard synchrotron emission model in the fast cooling regime. Shortly after prompt emission (similar to 1100 s), a bright (R = 14.0) optical emission hump with very steep rise (alpha similar to 5.5) was observed, which we interpret as the reverse shock (RS) emission. It is the first time that the rising phase of an RS component has been closely observed. The full optical and X-ray afterglow light curves can be interpreted within the standard reverse shock (RS) + forward shock (FS) model. In general, the high-quality prompt and afterglow data allow us to apply the standard fireball model to extract valuable information, including the radiation mechanism (synchrotron), radius of prompt emission (R-GRB similar to 3 x 10(13) cm), initial Lorentz factor of the outflow (Gamma(0) similar to 250), the composition of the ejecta (mildly magnetized), the collimation angle, and the total energy budget.</P>

      • Fiber hypertrophy and increased oxidative capacity can occur simultaneously in pig glycolytic skeletal muscle

        Scheffler, T. L.,Scheffler, J. M.,Park, S.,Kasten, S. C.,Wu, Y.,McMillan, R. P.,Hulver, M. W.,Frisard, M. I.,Gerrard, D. E. American Physiological Society 2014 American journal of physiology. Cell physiology Vol.306 No.4

        <P>An inverse relationship between skeletal muscle fiber cross-sectional area (CSA) and oxidative capacity suggests that muscle fibers hypertrophy at the expense of oxidative capacity. Therefore, our objective was to utilize pigs possessing mutations associated with increased oxidative capacity [AMP-activated protein kinase (AMPKγ<SUB>3</SUB><SUP>R200Q</SUP>)] or fiber hypertrophy [ryanodine receptor 1 (RyR1<SUP>R615C</SUP>)] to determine if these events occur in parallel. Longissimus muscle was collected from wild-type (control), AMPKγ<SUB>3</SUB><SUP>R200Q</SUP>, RyR1<SUP>R615C</SUP>, and AMPKγ<SUB>3</SUB><SUP>R200Q</SUP>-RyR1<SUP>R615C</SUP> pigs. Regardless of AMPK genotype, RyR<SUP>R615C</SUP> increased fiber CSA by 35%. In contrast, AMPKγ<SUB>3</SUB><SUP>R200Q</SUP> pig muscle exhibited greater citrate synthase and β-hydroxyacyl CoA dehydrogenase activity. Isolated mitochondria from AMPKγ<SUB>3</SUB><SUP>R200Q</SUP> muscle had greater maximal, ADP-stimulated oxygen consumption rate. Additionally, AMPKγ<SUB>3</SUB><SUP>R200Q</SUP> muscle contained more (∼50%) of the mitochondrial proteins succinate dehydrogenase and cytochrome <I>c</I> oxidase and more mitochondrial DNA. Surprisingly, RyR1<SUP>R615C</SUP> increased mitochondrial proteins and DNA, but this was not associated with improved oxidative capacity, suggesting that altered energy metabolism in RyR1<SUP>R615C</SUP> muscle influences mitochondrial proliferation and protein turnover. Thus pigs that possess both AMPKγ3<SUP>R200Q</SUP> and RyR<SUP>R615C</SUP> exhibit increased muscle fiber CSA as well as greater oxidative capacity. Together, our findings support the notion that hypertrophy and enhanced oxidative capacity can occur simultaneously in skeletal muscle and suggest that the signaling mechanisms controlling these events are independently regulated.</P>

      • KCI등재

        Suboptimal control strategy in structural control implementation

        J. Y. Xu,Q. S. Li,G. Q. Li,J. R. Wu,J. Tang 국제구조공학회 2005 Structural Engineering and Mechanics, An Int'l Jou Vol.19 No.1

        The suboptimal control rule is introduced in structural control implementation as an alternative over the optimal control because the optimal control may require large amount of processing time when applied to complex structural control problems. It is well known that any time delay in structural control implementation will cause un-synchronized application of the control forces, which not only reduce the effectiveness of an active control system, but also cause instability of the control system. The effect of time delay on the displacement and acceleration responses of building structures is studied when the suboptimal control rule is adopted. Two examples are given to show the effectiveness of the suboptimal control rule. It is shown through the examples that the present method is easy in implementation and high in efficiency and it can significantly reduce the time delay in structural control implementation without significant loss of performance.

      • SCIESCOPUSKCI등재

        Effect of Triticale Dried Distillers Grains with Solubles on Ruminal Bacterial Populations as Revealed by Real Time Polymerase Chain Reaction

        Wu, R.B.,Munns, K.,Li, J.Q.,John, S.J.,Wierenga, K.,Sharma, R.,Mcallister, T.A. Asian Australasian Association of Animal Productio 2011 Animal Bioscience Vol.24 No.11

        Real time PCR was used in this study to determine the effect of triticale dried distillers grains with solubles (TDDGS) as a replacement for grain or barley silage in finishing diets on the presence of six classical ruminal bacterial species (Succinivibrio dextrinosolvens, Selenomonas ruminantium, Streptococcus bovis, Megasphaera elsdenii, Prevotella ruminicola and Fibrobacter succinogenes) within the rumen contents of feedlot cattle. This study was divided into a step-wise adaptation experiment (112 days) that examined the effects of adaptation to diets containing increasing levels of TDDGS up to 30% (n = 4), a short-term experiment comparing animals (n = 16) fed control, 20%, 25% or 30% TDDGS diets over 28 days, and a rapid transition experiment (56 days) where animals (n = 4) were rapidly switched from a diet containing 30% TDDGS to a barley-based diet with no TDDGS. It was found that feeding TDDGS as replacement for barley grain (control vs. 20% TDDGS) decreased 16S rRNA copy numbers of starch-fermenting S. ruminantium and S. bovis (p<0.001 and p = 0.04, respectively), but did not alter 16S rRNA copy numbers of the other rumen bacteria. Furthermore, feeding TDDGS as a replacement barley silage (20% vs. 25% and 30% TDDGS) increased 16S rRNA copy numbers of S. ruminantium, M. elsdenii and F. succinogenes (p<0.001; p = 0.03 and p<0.001, respectively), but decreased (p<0.001) the 16S rRNA copy number of P. ruminicola. Upon removal of 30% TDDGS and return to the control diet, 16S rRNA copy numbers of S. ruminantium, M. elsdenii and F. succinogenes decreased (p = 0.01; p = 0.03 and p = 0.01, respectively), but S. dextrinosolvens and S. bovis increased (p = 0.04 and p = 0.009, respectively). The results suggest that replacement of TDDGS for grain reduces 16S rRNA copy numbers of starch-fermenting bacteria, whereas substitution for barley silage increases 16S rRNA copy numbers of bacteria involved in fibre digestion and the metabolism of lactic acid. This outcome supports the contention that the fibre in TDDGS is highly fermentable.

      • DISCOVERY OF GAMMA-RAY EMISSION FROM THE SUPERNOVA REMNANT Kes 17 WITH <i>FERMI</i> LARGE AREA TELESCOPE

        Wu, J. H. K.,Wu, E. M. H.,Hui, C. Y.,Tam, P. H. T.,Huang, R. H. H.,Kong, A. K. H.,Cheng, K. S. IOP Publishing 2011 ASTROPHYSICAL JOURNAL LETTERS - Vol.740 No.1

        <P>We report the discovery of GeV emission at the position of supernova remnant Kes 17 by using the data from the Large Area Telescope on board the Fermi Gamma-ray Space Telescope. Kes 17 can be clearly detected with a significance of similar to 12 sigma in the 1-20 GeV range. Moreover, a number of gamma-ray sources were detected in its vicinity. The gamma-ray spectrum of Kes 17 can be described well by a simple power law with a photon index of Gamma similar to 2.4. Together with the multiwavelength evidence for its interactions with the nearby molecular cloud, the gamma-ray detection suggests that Kes 17 is a candidate acceleration site for cosmic rays.</P>

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