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      • 시판 참기름 및 참깨제품의 진위판별에 있어서의 지방산 및 Sesamol 성분의 이용

        최효선,고영수 漢陽大學校 韓國生活科學硏究所 1995 韓國 生活 科學 硏究 Vol.- No.13

        An attempt was made to use the fatty acid and sesamol composition as a basis for the identification of sesame oil and sesame products adulteration. In 23 kinds sesame oil and 7 kinds of sesame and sesame products pressed experimentally, the ratio of oleic to linoleic acid content (O/L ratio) were in the variable ranges of 0.71-0.98. Only 14 among 30 collected sesame oils and sesame products were found to be pure sesame oil by fatly acid and sesamol content value determination. In 16 adulterated sesame oils, it was revealed 5 samples were adulted soybean oil, 4 with rice bran oil, 4 with corn and perilla seed oil and 3 with rape seed oil.

      • 유전알고리즘을 이용한 모터내장형 주축 시스템의 최적설계

        최영휴,박선균,김종무 國立 昌原大學校 産業技術硏究所 2002 産技硏論文集 Vol.16 No.-

        This study introduces the design optimization of a high speed spindle system for minimum critical speed, compliance, and weight using a genetic algorithm. The rotor, shaft, and bearing components are modelled as appropriate finite element respectively. In the design optimization, the length, inner and outer diameters of the shaft, bearing positions(or bearing span) and bearing stiffness were set as design variables. An unique objective function is obtained by multiplying an appropriate weighting factor by multi-objective functions, such as critical speed, compliance, and the total weight. The constraints are limitations of maximum critical speed, total weight, and vibration level of the spindle system. Optimization results show that critical speed, weight, and the compliance are reduced by 18.6%, 2.2% and 36% respectively compared with the initial design of the spindle system.

      • Comparison of anthracyclines used for induction chemotherapy in patients with <i>FLT3</i>-ITD-mutated acute myeloid leukemia

        Choi, Eun-Ji,Lee, Je-Hwan,Lee, Jung-Hee,Park, Han-Seung,Ko, Sun-Hye,Hur, Eun-Hye,Moon, Juhyun,Goo, Bon-Kwan,Kim, Yeonhee,Seol, Miee,Lee, Young-Shin,Kang, Young-Ah,Jeon, Mijin,Woo, Ji Min,Lee, Kyoo-Hyu Elsevier 2018 Leukemia research Vol.68 No.-

        <P><B>Abstract</B></P> <P>This retrospective analysis compared anthracyclines (as part of an induction regimen) in 128 newly diagnosed <I>FLT3</I>-ITD-mutated AML patients. Induction regimens comprised high-dose daunorubicin (HD-DN; 90 mg/m<SUP>2</SUP>/d × 3d; n = 44), standard-dose daunorubicin (SD-DN; 45 mg/m<SUP>2</SUP>/d × 3d; n = 51), or idarubicin (IDA; 12 mg/m<SUP>2</SUP>/d × 3d; n = 33) in combination with cytarabine (100–200 mg/m<SUP>2</SUP>/d × 7d). Fifty-three patients showing persistent leukemia on interim bone marrow examination received a second course of induction chemotherapy comprising 2 days of daunorubicin (45 mg/m<SUP>2</SUP>/d) or IDA (8 or 12 mg/m<SUP>2</SUP>/d) in addition to 5 days of cytarabine. Complete remission (CR) rates were 77.3%, 56.9%, and 69.7% for HD-DN, SD-DN, and IDA, respectively (<I>P</I> = 0.101; HD-DN <I>vs.</I> SD-DN, <I>P</I> = 0.036; HD-DN <I>vs.</I> IDA, <I>P</I> = 0.453; IDA <I>vs.</I> SD-DN, <I>P</I> = 0.237). The HD-DN showed higher overall survival (OS) and event-free survival (EFS) than SD-DN and IDA: the differences between HD-DN and SD-DN (<I>P</I> = 0.009 for OS and <I>P</I> = 0.010 for EFS) were statistically significant.</P> <P>Results of <I>in vitro</I> studies using <I>FLT3</I>-ITD-mutated cell lines supported these findings. In conclusion, HD-DN improved the CR rate, OS, and EFS of <I>FLT3</I>-ITD-mutated AML patients. HD-DN also tended to yield better outcomes than IDA, though the difference was not significant. The superiority of HD-DN over IDA should be confirmed in future studies.</P> <P><B>Highlights</B></P> <P> <UL> <LI> <I>FLT3</I>-ITD-mutated AML patients benefited from high-dose daunorubicin. </LI> <LI> High-dose daunorubicin seems to yield better results than idarubicin. </LI> <LI> The results of <I>in vitro</I> studies support these findings. </LI> </UL> </P>

      • 리니어 모터로 이송되는 탄성체의 진동 최소화를 위한 이송속도 최적화 연구

        최영휴,홍대선,최응영,최국진 국립7개대학공동논문집간행위원회 2005 공업기술연구 Vol.5 No.-

        Linear motor feed drive systems have been broadly used in machine tools or precision automatic systems. Recently, modern machine tools require high speed and high precision feed drive system to achieve high productivity. Unfortunately, a feed drive system, even though it was designed optimally, may experience severe transient vibrations during high-speed operation if its feed rate control is unsuitable. A rough feed rate curve having discontinuity in its acceleration profile causes serious vibrations in the feed slides system. This paper presents a feed rate optimization of a machine tool feed slide system, which is driven by a linear motor, for its minimum vibrations. Firstly, a 4-degree-of-freedom lumped parameter model is proposed for the vibration analysis of a linear motor driven machine tool feed drive system. Next, a feed rate optimization of the feed slide is carried out for minimum vibrations. The feed rate curve optimization strategy is to find out the most appropriate acceleration profile with jerk continuity. Of course, the optimized feed rate should approximate to the desired one as possible. A genetic algorithm with variable penalty function was used in this feed rate optimization.

      • Sampling Design of SSCs for Characterization at Shut-Down Power Plant

        Hyu Chang Choi,Jong Sun Hwang,Hye Jin Jung,Byong Sop Lim,Jong Hyuk Hong,Yo Gyeong Yun,Yoon Seok Kim 한국방사성폐기물학회 2023 한국방사성폐기물학회 학술논문요약집 Vol.21 No.2

        The radiological characterization of SSCs (Structure, Systems and Components) plays one of the most important role for the decommissioning of KORI Unit-1 during the preparation periods. Generally, a regulatory body and laws relating to the decommissioning focus on the separation and appropriate disposal or storage of radiological waste including ILW (intermediate level waste), LLW (low level waste), VLLW (very low level waste) and CW (clearance waste), aligned with their contamination characteristics. The result of the preliminary radiological characterization of KORI Unit-1 indicated that, apart from neutron activated the RV (reactor vessel), RVI (reactor vessel internals), and BS (biological shielding concrete), the majorities of contamination were sorted to be less than LLW. Radiological contamination can be evaluated into two methods. Due to the difficulties of directly measuring contamination on the interior surfaces of the pipe, called CRUD, the assessment was implemented by modeling method, that is measuring contamination on the exterior surfaces of the pipes and calculating relative factors such as thickness and size. This indirect method may be affected by the surrounding radiation distribution, and only a few gamma nuclides can be measured. Therefore, it has limitation in terms of providing detailed nuclide information. Especially, α and β nuclides can only be estimated roughly by scaling factors, comparing their relative ratios with the existing gamma results. To overcome the limitation of indirect measurement, a destructive sampling method has been employed to assess the contamination of the systems and component. Samples are physically taken some parts of the systems or components and subsequently analyzed in the laboratory to evaluate detailed nuclides and total contamination. For the characterization of KORI Unit-1, we conducted the radiation measurement on the exterior surfaces of components using portable instruments (Eberline E-600 SPA3, Thermo G20-10, Thermo G10, Thermo FH40TG) at BR (boron recycle system) and SP (containment spray system) in primary system. Based on these results, the ProUCL program was employed to determine the destructive sample collection quantities based on statistical approach. The total of 5 and 8 destructive sample quantities were decided by program and successfully collected from the BR and SP systems, respectively. Samples were moved to laboratory and analyzed for the detail nuclide characteristics. The outcomes of this study are expected to serve as valuable information for estimating the types and quantities of radiological waste generated by decommissioning of KORI Unit-1.

      • KCI등재

        Effect of Supplementation of Trehalose, Glycerol on Conventional Freezing and Vitrification of Boar Sperm

        Sun-Ho Choi,Mi-Jin Lee,Kyung-Mi Lee,Soo-Jin Sa,Hyun-Jong Kim,Hyun-Ju Jin,Yong-Sup Song,Jun-Cheol Park 한국수정란이식학회 2014 한국동물생명공학회지 Vol.29 No.4

        The boar sperm has more lipid droplets and specialty of seminal plasma compared with other species, causing difficulties of freezing sperm and decreases for the utilization of frozen semen into the artificial insemination. However, several studies reported significant results for the recovery of sperm motility and reproductive by addition of cryoprotectants and seminal plasma after thawing. This study was designed to investigate the effects of supplementation of trehalose or glycerol in the LEY (lactose and egg yolk in BTS) solution for the conventional freezing and vitrification process. Two boars aged 16 months were used to collect semen for 2 times in a week. The samples were allotted to 3 freezing solutions (LEY + glycerol 10.5% + OEP 1.5%, LEY + trehalose 1M + OEP 1.5%, and sucrose 1.5M + trehalose 1 M + OEP 1.5%) after centrifugation at 800 g for 10 minutes. Semen was equilibrated in freezing solutions for 10 minutes and injected into plastic straws with 2∼3 air bubbles to minimize freezing damages. Vitrification was performed to locate sperm in 5 cm above LN2 for 5 minutes, and the conventional freezing was conducted with an automatic freezer. Motility and survival rates were measured by CASA (Computer assisted sperm an alyzing system) and FITC (Fluorescein isothiocyanate), respectively after thawing semen at 50℃ for 12 seconds. The results were analyzed by ANOVA with STATVIEW statistical program. The vitrificatioin solution (LEY + 10.5% glycerol + 1.5% OEP) presented higher motility (20.9%) than other solutions while the solution (LEY + 1M trehalose + 1.5% OEP) showed the lowest (motility : 5.2%). However, survival rates of vitrified sperms detected by FITC showed 1~4% live sperms in almost of dead sperms at all vitrification solutions’ groups, but survival rate of freezing solution of LEY + 1M trehalose + 1.5% OEP LEY and LEY + 10.5% glycerol + 1.5% OEP were showed 49%, and 79%, respectively. There were differences (P<0.05) survival rate of conventional freezing in LEY + 10.5% glycerol + 1.5% OEP and LEY + 1M trehalose + 1.5% OEP and the remaining showed no differences. The results suggested that vitrified boar semen was not enough to be utilized for the artificial insemination, but it showed possibility to utilize for ICSI and conventional freezing with glycerol would be useful method for artificial insemination in pig while we choose the outstanding semen against tolerance to freezing damages.

      • KCI등재

        Effects of Rice Straw Incorporation by Cutting Methods on Soil Properties and Rice Yield in a Paddy Field

        Chang-Hyu Yang(양창휴),Taek-Kyum Kim(김택겸),Jin-Hee Ryu(유진희),Sang-Bog Lee(이상복),Sun Kim(김선),Nam-Hyun Baek(백남현),Weon-Young Choi(최원영),Doug-Young Chung(정덕영),Si-Ju Kim(김시주) 한국토양비료학회 2010 한국토양비료학회지 Vol.43 No.6

        본 연구는 논토양 비옥도에 대한 예취높이별 볏짚 혼입효과를 구명하고자 수행하였다. 예취높이별 잔존량은 1,420 kg ha<SUP>-1</SUP> (10 cm), 1,850 kg ha<SUP>-1</SUP> (15 cm), 2,400 kg ha<SUP>-1</SUP> (20 cm)를 나타냈다. 볏짚 혼입으로 토양경도, 용적밀도는 낮아졌고 공극 률이 증가하여 토양물리성이 개선되었다. 볏짚 수거로 토양유기물, 유효인산 및 유효규산 함량이 적어지고 양이온치환용량 이 낮아졌다. 토양에 볏짚 혼입시 비옥도 감소 폭이 적었고 예취높이별 잔존량이 많을수록 혼입효과가 크게 나타났다. 볏짚 혼입에 따라 수수, 영화수 확보가 많고 등숙비율이 높아졌으며 쌀수량은 관행 (3.67 Mg ha<SUP>-1</SUP>)대비 28~32% 증수되었다. 연구결과 예취방법에 의하여 볏짚을 혼입한 재배기술이 수거에 비하여 쌀수량을 증가시켰고 논토양을 개선하였다. This study was to investigate the effects of rice straw incorporation by cutting height on paddy soil fertility. The average residual amount of rice straw by cutting height were showed 1,420 kg ha<SUP>-1</SUP>, 1,850 kg ha<SUP>-1</SUP>, and 2,400 kg ha<SUP>-1</SUP> for depths of 10 cm, 15 cm, and 20 cm, respectively. For soil physical properties, soil hardness and bulk density were decreased while porosity was increased by rice straw incorporation. But soil organic matter (SOM), available silicate content, and cation exchange capacity (CEC) were significantly decreased when rice straw was removed from the field. These results indicated that the SOM as residual amount of rice straw was influenced by level of cutting height. Milled rice yield was increased by 28% and 32% for cutting heights of 15 cm and 20 cm, compared with that of control, respectively. The number of spikelets per square meter and the percentage of ripeness were increased with increasing incorporation by lower level of cutting height of rice straw. Therefore, incorporation of rice straw practices under cutting method influenced soil improvement and rice yield in paddy field.

      • KCI등재

        새만금 신간척지 토양의 염농도별 식생특성

        김선(Sun Kim),김택겸(Taek-Kyum Kim),정재혁(Jae-Hyeok Jeong),양창휴(Chang-Hyu Yang),이장희(Jang-Hee Lee),최원영(Weon-Young Choi),김영두(Young-Doo Kim),김시주(Si-Ju Kim),성기영(Ki-Young Seong) 韓國雜草學會 2012 Weed&Turfgrass Science Vol.32 No.1

        간척지를 농업용지로 개발하는데 간척지에 자생하는 식생의 이용가능성에 관한 기초 자료를 얻고자 새만금 간척지 내 계화지구에서 식생군락에 따라 식물종을 분류하고 토양 화학성과의 관계를 분석한 결과는 다음과 같다. 담수면 토양을 기점으로 조사된 위치별 토양염농도는 담수면 인접부가 22.3dS m-1 로 가장 높았고 육지쪽으로 진행될수록 낮아져 해수면에서 2km이상 되는 지점에서는 1.1~3.44dS m-1를 나타냈다. 자생하는 식물은 6과 26종이 조사되었으며, 식물종별 발생빈도는 갯개미취, 비짜루국화가 61.5로 가장 높은 빈도를 나타냈고, 이어 갈대와 갯꾸러미풀이 53.8이었다. 식생의 발생은 토양 염농도 14dS m-1 지점에서 시작되었고 주로 명아주과 염생식물들인 퉁퉁마디, 나문재, 칠면초, 해홍나물 등이 나타났다. 이후 6.7dS m-1지점에서부터 화본과 식물인 갈대, 갯꾸러미풀 등이 나타났고, 5dS m-1 에서 사초과 식물이 나타났다. 3dS m-1이하에서는 비짜루국화, 갈대, 피, 갯잔디, 망초 등 중성식물들이 나타났다. 식생 종수는 염생식물과 중생식물이 동시에 나타나는 5dS m-1 지점에서 많았고, Biomass는 갈대가 우점한 식생구가 가장 많았으며, 다음으로는 갈대+자귀풀이 우점한 식생에서 많았다. 식생의 생장량은 토양 염농도와는 부의상관을 나타냈고, 유기물함량과는 정의상관을 나타냈으며, pH와 식생의 우점도간에는 부의 상관을 나타냈다. This study was conducted to survey vegetation changes and soil characteristics in Saemangeum new reclaimed tidal land. Soil salinity in border area to tidal land was 22.3 dS m-1 but showed 1.1~3.44 dS m-1 over the distance of 2 km from border line. The vascular plants in survey sites were recorded as total 26 taxa in 6 families. The frequency of species appearance of Aster tripolium, A. subulatus var. sandwicensis were highest by 61.5 and that of Phragmites communis, Puccinellia nipponica were 53.8. The almost vegetations occurred in the patch which range of soil salinity 14 dS m-1 were halophytes as Salicornia europaea, Suaeda asparagoides, S. japonica. As lowed soil salinity as 6.7 dS m-1, mixed vegetation of halophytes with P. communis, P. nipponica, Carex pumila were occurred. Dominant species in the range of 3.0 dS m-1 area were A. subulatus var. sandwicensis, P. communis, Echinochloa spp., Zoysia sinica and Conyza canadensis. Biomass production was the highest in the area of dominant vegetation with P. communis, and mixed zone with P. communis and Aeschynomene indica are followed. The correlation between vegetation biomass and soil salinity, soil pH and dominance index of vegetation were negative. But that of vegetation biomass and soil organic content were positive.

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