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      • Efficient Query Processing Platform for Uncertain Big Data

        Zhenhua Huang,Jiawen Zhang,Qiang Fang 보안공학연구지원센터 2015 International Journal of Database Theory and Appli Vol.8 No.5

        Query processing technology has recently received a lot of attention in the business intelligence and information service communities. However, the existing approaches can not efficiently optimize the query performance in the uncertain big data environment. In this paper, we propose QPPUBG, a novel and efficient query processing platform for uncertain big data. QPPUBG mainly includes four modules: (i) query equivalence reconstructing for uncertain big data; (ii) multiple query optimization over probability relation components; (iii) query execution plan constructing over probability relation components, and (iv) physical implementation solution of query for uncertain big data. Specially, QPPUBG can support the possible world instance semantics and efficiently handle arbitrary decision spaces. Moreover, QPPUBG can seamlessly integrate the above four modules into the modern parallel computation frameworks. We present the extensive experiments that demonstrate QPPUBG is both efficient and effective.

      • KCI등재

        Resistance Behaviours of Clamped HFR-LWC Beam Using Membrane Approach

        Wanxiang Chen,Jiawen Cai,Junxuan Huang,Xiaoyu Yang,Jianjun Ma 한국콘크리트학회 2024 International Journal of Concrete Structures and M Vol.18 No.3

        Beam-like members sustaining the combined action of transverse load and membrane force exhibit a special load response to progressive deflection. A theoretical model is therefore developed to depict the resistance behaviours of clamped reinforced concrete (RC) beams observed in tests. The support-induced membrane effects are simulated by a longitudinal spring and a rotational spring. The load responses to progressive deflection are obtained using the membrane approach, and the prediction accuracies of proposed method are validated by a series of four-point bending tests on hybrid fibre reinforced-lightweight aggregate concrete (HFR-LWC) beam. It is illustrated that the bearing capacities of clamped HFR-LWC beam are significantly enhanced by the membrane effect. Ultimate load of the clamped beam ranges from 64.0 to 184.0 kN, and the larger bearing capacity compared with simply supported beam is obtained. An ultimate load of 1.85 to 5.31 times the yield line value is achieved, and thereby, the ultimate resistance of the clamped beam might be seriously underestimated using yield line approach. A strong support constraint is beneficial for increasing the load-carrying capacity of clamped HFR-LWC beam, although the large longitudinal restraint stiffness would inevitably gives rise to brittle failure. The relative errors between predicted load and measured value are less than 7.23%, indicating that the presented model is a promising tool to estimate the ultimate load of clamped beam-like member.

      • SCISCIESCOPUS

        High speed intravascular photoacoustic imaging with fast optical parametric oscillator laser at 1.7 <i>μ</i>m

        Piao, Zhonglie,Ma, Teng,Li, Jiawen,Wiedmann, Maximilian T.,Huang, Shenghai,Yu, Mingyue,Kirk Shung, K.,Zhou, Qifa,Kim, Chang-Seok,Chen, Zhongping American Institute of Physics 2015 Applied Physics Letters Vol.107 No.8

        <P>Intravascular photoacoustic imaging at 1.7 mu m spectral band has shown promising capabilities for lipid-rich vulnerable atherosclerotic plaque detection. In this work, we report a high speed catheter-based integrated intravascular photoacoustic/intravascular ultrasound (IVPA/IVUS) imaging system with a 500 Hz optical parametric oscillator laser at 1725 nm. A lipid-mimicking phantom and atherosclerotic rabbit abdominal aorta were imaged at 1 frame per second, which is two orders of magnitude faster than previously reported in IVPA imaging with the same wavelength. Clear photoacoustic signals by the absorption of lipid rich deposition demonstrated the ability of the system for high speed vulnerable atherosclerotic plaques detection. (C) 2015 AIP Publishing LLC.</P>

      • KCI등재

        Efficient mercury removal from flue gas using high-quality spinel mixed ferrites obtained from wastewater

        Daorong Sun,Zhen Li,Shouqiang Huang,Fengli Yang,Jiawen Chi,Songjian Zhao 한국공업화학회 2021 Journal of Industrial and Engineering Chemistry Vol.100 No.-

        High-quality spinel mixed ferrites (M-Fe) are obtained from the electroplating wastewater, which arethen used as adsorbents for the removal of elemental mercury (Hg0) in theflue gas to simultaneouslyrealize the purpose of waste resource utilization and pollution control. In the “ferrite process”, throughadjusting the dosages of ferrous sulfate (FeSO4 7H2O), the chromium (Cr) in wastewater can be fullyrecycled to synthesize the M-Fe adsorbents with good crystal morphology and chemical stability, andthey can be easily separated by applying a magneticfield. Hg0 removal experiments indicated that thefeeding mass ratio of FeSO4 7H2O: Cr6+ and temperatures had great influence on mercury removalefficiency, and the M-Fe adsorbents with FeSO4 7H2O: Cr6+ mass ratio of 100: 1 (M-Fe (100)) had thehighest Hg0 removal performance with nearly 100% at 100℃. In addition, M-Fe (100) presented goodsulfur resistance, which remained above 90% Hg0 removal efficiency after SO2 injection, and it can recoveractivity when stopping SO2. The XPS and desorption dynamics analysis showed mercury existed in theform of physically and chemically adsorbed states. Adsorption kinetic studies manifested that surfaceactive sites were the adsorption rate controlling step, and inner active sites played an important role inmercury adsorption process. Mercury equilibrium analysis indicated mercury amount during adsorptionand desorption process was approximately identical, manifesting M-Fe (100) was well recyclablemagnetic adsorbent.

      • KCI등재

        Self-regulated learning strategies and student video engagement trajectory in a video-based asynchronous online course: a Bayesian latent growth modeling approach

        김동호,조일현,송동길,Hua Zheng,Li, Jingwei,Zhu, Jiawen,Huang, Xing,Yan, Wei,Xu, Zhen 서울대학교 교육연구소 2021 Asia Pacific Education Review Vol.22 No.2

        The self-paced nature of asynchronous online learning (AOL) is recognized as an obstacle that disrupts student success in the learning environment. Without on-time interventions provided by instructors, students find it challenging to use learning strategies tailored to the learning environment, and their use of self-regulated learning (SRL) strategies has been regarded one of the key indicators of success in AOL. To examine how student SRL strategies are associated with their video engagement trajectory and learning outcomes, we used student video engagement data collected at multiple time points. Participants were 159 students who were taking a self-paced asynchronous online statistics course. Results revealed that student video engagement was found to increase over time and student management strategies contributed to the upward change. We also found that the growth of engagement predicted student achievement in the course. Our findings shed light on instructional strategies to support students in AOL contexts.

      • KCI등재

        Analysis of the Transcriptome of Polygonatum odoratum (Mill.) Druce Uncovers Putative Genes Involved in Isofavonoid Biosynthesis

        Shengxiang Zhang,Yuanyuan Shi,Chunmiao Shan,Liqiang Zhao,Kelong Ma,Luqi Huang,Jiawen Wu 한국식물학회 2020 Journal of Plant Biology Vol.63 No.3

        Polygonatum odoratum (Mill.) Druce (P. odoratum) is a traditional Chinese herb. The isofavonoids of P. odoratum are important medicinal bioactive compounds for the treatment of hypoimmunity, rheumatic heart disease, cardiovascular diseases, and diabetes. This study used RNA sequencing to identify potential genes regulating isofavonoid biosynthesis in P. odoratum. To do this, we generated an overview of metabolic and secondary metabolic pathways, using MAPMAN, and identifed 96 genes encoding seven key enzymes involved in isofavonoid biosynthesis through their KEGG annotation. Alignment of phenylalanine ammonia-lyase or chalcone synthase amino acid sequences revealed well-conserved sequences, spatial structures, and active sites. We also verifed the expression of key genes encoding phenylalanine ammonia-lyase and chalcone synthase by quantitative real-time PCR (qRT-PCR). This analysis of the isofavonoid biosynthesis pathway and its crucial enzymes in P. odoratum lays the foundation for uncovering the regulatory mechanism of isofavonoid biosynthesis.

      • KCI등재

        Inhibition of Fatty Acid β-Oxidation by Fatty Acid Binding Protein 4 Induces Ferroptosis in HK2 Cells Under High Glucose Conditions

        Zhihua Zheng,Jiasi Chen,Keping Wu,Yan Lei,Mingcheng Huang,Lokyu Cheng,Hui Guan,Jiawen Lin,Ming Zhong,Xiaohua Wang 대한내분비학회 2023 Endocrinology and metabolism Vol.38 No.2

        Background: Ferroptosis, which is caused by an iron-dependent accumulation of lipid hydroperoxides, is a type of cell death linked todiabetic kidney disease (DKD). Previous research has shown that fatty acid binding protein 4 (FABP4) is involved in the regulation of ferroptosis in diabetic retinopathy. The present study was constructed to explore the role of FABP4 in the regulation of ferroptosis in DKD. Methods: We first detected the expression of FABP4 and proteins related to ferroptosis in renal biopsies of patients with DKD. Then, we used a FABP4 inhibitor and small interfering RNA to investigate the role of FABP4 in ferroptosis induced by high glucosein human renal proximal tubular epithelial (HG-HK2) cells. Results: In kidney biopsies of DKD patients, the expression of FABP4 was elevated, whereas carnitine palmitoyltransferase-1A (CPT1A), glutathione peroxidase 4, ferritin heavy chain, and ferritin light chain showed reduced expression. In HG-HK2 cells, the induction of ferroptosis was accompanied by an increase in FABP4. Inhibition of FABP4 in HG-HK2 cells changed the redox state, suppressing the production of reactive oxygen species, ferrous iron (Fe2+), and malondialdehyde, increasing superoxide dismutase, and reversing ferroptosis-associated mitochondrial damage. The inhibition of FABP4 also increased the expression of CPT1A, reversed lipiddeposition, and restored impaired fatty acid β-oxidation. In addition, the inhibition of CPT1A could induce ferroptosis in HK2 cells. Conclusion: Our results suggest that FABP4 mediates ferroptosis in HG-HK2 cells by inhibiting fatty acid β-oxidation.

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