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Engineered Probiotics for the Management of Congenital Metabolic Diseases: A Systematic Review
Meisam Barati,Erfan Mosharkesh,Amir Hossein Tahmassian,Maryam Khodaei,Masoumeh Jabbari,Ali Kalhori,Mohsen Alipour,Afshin Abdi Ghavidel,Sajad Khalili-Moghadam,Anwar Fathollahi,Sayed Hossein Davoodi 한국식품영양과학회 2024 Preventive Nutrition and Food Science Vol.29 No.1
Engineered probiotics (EPs) can be used to treat/manage chronic and congenital diseases. However, to the best of our knowledge, no systematic review has evaluated the effects of EPs on congenital metabolic disorders in murine models and human subjects. Thus, the present study systematically reviewed interventional studies that assessed the effects of EPs on congenital metabolic disorders. PubMed, Web of Science, and Scopus databases were searched up to February 2023 to retrieve related publications. Seventy-six articles were obtained in the primary step. After screening the titles/abstracts based on the inclusion and exclusion criteria, 11 papers were included. Finally, only seven articles were included after performing full-text evaluation. The included articles evaluated the effects of EPs on managing phenylketonuria (PKU, n=4) and hyperammonemia (n=3). Moreover, these studies examined mice and/or rats (n=6), monkeys (n=1), and humans (n=2). Studies on EPs and hyperammonemia revealed that some wild strains such as Lactobacillus plantarum have an innate ammonia-hyper-consuming potential; thus, there was no need to manipulate them. However, manipulation is needed to obtain a phenylalanine- metabolizing strain. In conclusion, EPs can be used to manage or treat congenital metabolic diseases including PKU.
Hossein Farahani,Farzan Barati 국제구조공학회 2015 Structural Engineering and Mechanics, An Int'l Jou Vol.53 No.3
This paper focuses on vibration analysis of functionally graded cylindrical shell submerged in an incompressible fluid. The equation is established considering axial and lateral hydrostatic pressure based on first order shear deformation theory of shell motion using the wave propagation approach and classic Flügge shell equations. To study accuracy of the present analysis, a comparison carried out with a known data and the finite element package ABAQUS. With this method the effects of shell parameters, m, n, h/R, L/R, different boundary conditions and different power-law exponent of material of functionally graded cylindrical shells, on the frequencies are investigated. The results obtained from the present approach show good agreement with published results.
Discharge Coefficient and Energy Dissipation over Stepped Spillway under Skimming Flow Regime
Hossein Shahheydari,Ehsan Jafari Nodoshan,Reza Barati,Mehdi Azhdary Moghadam 대한토목학회 2015 KSCE JOURNAL OF CIVIL ENGINEERING Vol.19 No.4
Stepped spillways have a wide range of applicability as a hydraulic structure in large dams to dissipate energy of high-velocity flows at a downstream area of dams as well as release overflows into the downstream. In this study, the numerical simulation of the flow over the stepped spillway was investigated by using Flow3D software as an analytic flow field. The RNG k-ε model was applied as the turbulence model, and Volume of Fluid (VOF) model was used to determine the free surface flow profiles. At the first stage, the model was verified by reliable experimental data. Then, in order to investigate the various features of skimming flow regime, 112 numerical spillway models was designed, which 96 models were stepped spillway models and 16 models were smooth spillway models (i.e., WES profile). In these numerical experiment, two step sizes, six configuration, four passing discharge and four profile slopes (15, 30, 45 and 60 degrees) with various relative discharges were considered to investigate the energy dissipation and discharge coefficient rates. The results indicated that discharge coefficient rate and energy dissipation rate have inverse relationship. Also it was observed that when relative discharges increased, energy dissipation rate decreased and discharge coefficient rate increased.
Farahani, Hossein,Barati, Farzan Techno-Press 2015 Structural Engineering and Mechanics, An Int'l Jou Vol.53 No.3
This paper focuses on vibration analysis of functionally graded cylindrical shell submerged in an incompressible fluid. The equation is established considering axial and lateral hydrostatic pressure based on first order shear deformation theory of shell motion using the wave propagation approach and classic Fl$\ddot{u}$gge shell equations. To study accuracy of the present analysis, a comparison carried out with a known data and the finite element package ABAQUS. With this method the effects of shell parameters, m, n, h/R, L/R, different boundary conditions and different power-law exponent of material of functionally graded cylindrical shells, on the frequencies are investigated. The results obtained from the present approach show good agreement with published results.
Equivalent material properties of perforated metamaterials based on relative density concept
Mohammad Reza Barati,Hossein Shahverdi 국제구조공학회 2022 Steel and Composite Structures, An International J Vol.44 No.5
In this paper, the equivalent material properties of cellular metamaterials with different types of perforations have been presented using finite element (FE) simulation of tensile test in Abaqus commercial software. To this end, a Representative Volume Element (RVE) has been considered for each type of cellular metamaterial with regular array of circular, square, oval and rectangular perforations. Furthermore, both straight and perpendicular patterns of oval and rectangular perforations have been studied. By applying Periodic Boundary conditions (PBC) on the RVE, the actual behavior of cellular material under uniaxial tension has been simulated. Finally, the effective Young’s modulus, Poisson’s ratio and mass density of various metamaterials have been presented as functions of relative density of the RVE.
Mohammad Reza Barati,Hossein Shahverdi 국제구조공학회 2016 Structural Engineering and Mechanics, An Int'l Jou Vol.60 No.4
In this paper, thermal vibration of a nonlocal functionally graded (FG) plates with arbitrary boundary conditions under linear and non-linear temperature fields is explored by developing a refined shear deformation plate theory with an inverse cotangential function in which shear deformation effect was involved without the need for shear correction factors. The material properties of FG nanoplate are considered to be temperature-dependent and graded in the thickness direction according to the Mori-Tanaka model. On the basis of non-classical higher order plate model and Eringen’s nonlocal elasticity theory, the small size influence was captured. Numerical examples show the importance of non-uniform thermal loadings, boundary conditions, gradient index, nonlocal parameter and aspect and side-to-thickness ratio on vibrational responses of size-dependent FG nanoplates.
Mohammad Mashhour,Mohammad Reza Barati,Hossein Shahverdi 국제구조공학회 2023 Steel and Composite Structures, An International J Vol.46 No.5
In the present work, the flutter characteristics of porous nanocomposite cylindrical shells, reinforced with graphene platelets (GPLs) in supersonic airflow, have been investigated. Different distributions for GPLs and porosities have been considered which are named uniform and non-uniform distributions thorough the shell’s thickness. The effective material properties have been determined via Halpin-Tsai micromechanical model. The cylindrical shell formulation considering supersonic airflow has been developed in the context of first-order shell and first-order piston theories. The governing equations have been solved using Galerkin’s method to find the frequency-pressure plots. It will be seen that the flutter points of the shell are dependent on the both amount and distribution of porosities and GPLs and also shell geometrical parameters.
Differential Effects of FonF and FonFS on Learning English Lax Vowels in an EFL Context
Farhad Tabandeh,Ahmad Moinzadeh,Hossein Barati 아시아테플 2019 The Journal of Asia TEFL Vol.16 No.2
This study investigated the differential effects of focus-on-form (FonF: explicit instruction followed by focused tasks) and focus-on-forms (FonFS: explicit instruction followed by controlled exercises) on learning English lax vowels (i.e., /ɪ/, /ʊ/, /ʌ/) by Persian English as a foreign language (EFL) learners. To this end, 48 learners took a voluntary 6-hour course: the experimental group (n = 17) received FonF, the comparison group (n = 16) received FonFS, and the control group (n = 15) engaged in theme-based discussions with no focus on the target vowels. Learners’ pronunciations were elicited in controlled read-aloud and spontaneous picture description tasks and acoustically measured for phonetic accuracy based on tongue positions (i.e., formant 1 [F1] for the height and formant 2 [F2] for the backness of the tongue). Results revealed that whereas both instructional types significantly improved learners’ phonetic accuracy (i.e., adjusting F1/F2 values) in the controlled task, only the FonF methodology proved effective in the spontaneous task with large effects in the delayed posttest. The control group revealed no improvement in any tasks. Overall, the results show that FonF instruction may offer substantial benefits to EFL learners to have more accurate pronunciations in EFL speech. The paper concludes with the pedagogical implications of the findings.
Visceral Leishmaniasis in Rural Areas of Alborz Province of Iran and Implication to Health Policy
Aliehsan Heidari,Mehdi Mohebali,Kourosh Kabir,Hojatallah Barati,Yousef Soultani,Hossein Keshavarz,Behnaz Akhoundi,Homa Hajjaran,Hosein Reisi 대한기생충학열대의학회 2015 The Korean Journal of Parasitology Vol.53 No.4
Optimal Design of Labyrinth Spillways using Meta-Heuristic Algorithms
Khosrow Hosseini,Ehsan Jafari Nodoushan,Reza Barati,Hossein Shahheydari 대한토목학회 2016 KSCE JOURNAL OF CIVIL ENGINEERING Vol.20 No.1
The labyrinth spillway continues to be a popular type of the control structures. The focus of the present study is that on the optimization of the shape of the labyrinth spillway through the minimization of the construction costs because the use of it is a suitable solution in the rehabilitation process of existing reservoirs. An Adaptive Neural Fuzzy Inference System (ANFIS) model was developed to determine the discharge coefficient of the labyrinth spillway as a function of the angle between alignment of the crest and direction of flow, the relative depth of flow over spillway and its crest height. Differential Evolution (DE) algorithm and Genetic Algorithm (GA) were adopted to minimize the spillway cost as the objective function by considering certain hydraulic conditions as the constraints of the optimization procedure. The results indicated that DE and GA can respectively reduce 19.3% and 16.6% the construction cost of a real benchmark design.