http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Effects of double-atom vacancies on the electronic properties of graphyne: a DFT investigation
Wu, Si,Yuan,Ai, Hongqi,Lee, Jin Yong,Kang, Baotao The Royal Society of Chemistry 2018 Physical chemistry chemical physics Vol.20 No.35
<P>Vacancy defects are one of the key impurities that strongly affect the properties of materials. In the present study, some different double-atom vacancies were introduced into α-graphyne (Gy), βGy, and γGy, depending on their own structural characteristics. Subsequently, density functional theory (DFT) calculations were carried out to evaluate the changes in the structural and electronic properties induced by the double-atom vacancies. The results indicated that the double-atom vacancies only lead to an in-plane structural rearrangement of all three of the Gy systems. It was further revealed that the position of the double-atom vacancies is a crucial factor in the manipulation of the electronic properties of αGy and βGy as compared with γGy. Our work is expected to yield new Gy materials with the desired properties obtained by altering the position of induced double-atom vacancies.</P>
Regulation of cuticular wax biosynthesis in plants under abiotic stress
Md Shaheenuzzamn,Shandang Shi,Kamran Sohail,Hongqi Wu,Tianxiang Liu,Peipei An,Zhonghua Wang,Mirza Hasanuzzaman 한국식물생명공학회 2021 Plant biotechnology reports Vol.15 No.1
Cuticular waxes are the covering of the outer layer of the plant, consist of hydrocarbon appears like whitish flm or bloom in plant organs. They play a vital role like a safeguard from diferent stress condition in the plant. Since environmental factors are active regulators of cuticular wax biosynthesis, composition, quantity, and deposition, it is evident that cuticular wax is associated with plant stress responses. The diversity of cuticular wax compositions is a proof of the wealth of genes associated in plant wax production. Moreover, a number of wax genes were distinguished in plant/crops at abiotic stress conditions but, regulation of control of those wax genes has not been studied very well in major crop plants at abiotic conditions. A very few transcriptions factors were identifed to regulate the expression level of wax genes of cuticular wax biosynthesis at abiotic stress condition. However, further study is needed to identify more candidate transcriptional regulation factors to cuticular wax production in diferent crop plants in diverse abiotic environments. Therefore, regulation of cuticular wax production under diverse abiotic stresses and the role of transcription factors into the plant cuticular wax accumulation will be helpful to engineer crop plants and improve transgenic crops for stress tolerance. In this review, we focused on a new perspective on transcriptional factors to regulate functional genes of cuticular wax biosynthesis in plants at abiotic stresses.
Decorin: a potential therapeutic candidate for ligamentum flavum hypertrophy by antagonizing TGF-β1
Wang Shanxi,Qu Yunkun,Fang Xuan,Ding Qing,Zhao Hongqi,Yu Xiaojun,Xu Tao,Lu Rui,Jing Shaoze,Liu Chaoxu,Wu Hua,Liu Yang 생화학분자생물학회 2023 Experimental and molecular medicine Vol.55 No.-
Ligamentum flavum hypertrophy (LFH) is the main physiological and pathological mechanism of lumbar spinal canal stenosis (LSCS). The specific mechanism for LFH has not been completely clarified. In this study, bioinformatic analysis, human ligamentum flavum (LF) tissues collection and analysis, and in vitro and in vivo experiments were conducted to explore the effect of decorin (DCN) on LFH pathogenesis. Here, we found that TGF-β1, collagen I, collagen III, α-SMA and fibronectin were significantly upregulated in hypertrophic LF samples. The DCN protein expression in hypertrophic LF samples was higher than that in non-LFH samples, but the difference was not significant. DCN inhibited the expression of TGF-β1-induced fibrosis-associated proteins in human LF cells, including collagen I, collagen III, α-SMA, and fibronectin. ELISAs showed that TGF-β1 can upregulate PINP and PIIINP in the cell supernatant, and this effect was inhibited after DCN administration. Mechanistic studies revealed that DCN suppressed TGF-β1-induced fibrosis by blocking the TGF-β1/SMAD3 signaling pathway. In addition, DCN ameliorated mechanical stress-induced LFH in vivo. In summary, our findings indicated that DCN ameliorated mechanical stress-induced LFH by antagonizing the TGF-β1/SMAD3 signaling pathway in vitro and in vivo. These findings imply that DCN is a potential therapeutic candidate for ligamentum flavum hypertrophy.