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      • KCI등재

        Distribution of elastic fibers in the head and neck: a histological study using late-stage human fetuses

        Hideaki Kinoshita,Takashi Umezawa,Yuya Omine,Masaaki Kasahara,José,Francisco Rodrí,guez-Vá,zquez,Gen Murakami,Shinichi Abe 대한해부학회 2013 Anatomy & Cell Biology Vol.46 No.1

        There is little or no information about the distribution of elastic fibers in the human fetal head. We examined this issue in 15 late-stage fetuses (crown-rump length, 220–320 mm) using aldehyde-fuchsin and elastica-Masson staining, and we used the arterial wall elastic laminae and external ear cartilages as positive staining controls. The posterior pharyngeal wall, as well as the ligaments connecting the laryngeal cartilages, contained abundant elastic fibers. In contrast with the sphenomandibular ligament and the temporomandibular joint disk, in which elastic fibers were partly present, the discomalleolar ligament and the fascial structures around the pterygoid muscles did not have any elastic fibers. In addition, the posterior marginal fascia of the prestyloid space did contain such fibers. Notably, in the middle ear, elastic fibers accumulated along the tendons of the tensor tympani and stapedius muscles and in the joint capsules of the ear ossicle articulations. Elastic fibers were not seen in any other muscle tendons or vertebral facet capsules in the head and neck. Despite being composed of smooth muscle, the orbitalis muscle did not contain any elastic fibers. The elastic fibers in the sphenomandibular ligament seemed to correspond to an intermediate step of development between Meckel’s cartilage and the final ligament. Overall, there seemed to be a mini-version of elastic fiber distribution compared to that in adults and a different specific developmental pattern of connective tissues. The latter morphology might be a result of an adaptation to hypoxic conditions during development.

      • Effectiveness of Priority Control Method by Using Cgroups in KVM

        Ryoji Kinoshita,Hideaki Moriyama,Yohei Ishikawa,Akira Suganuma 대한전자공학회 2015 ITC-CSCC :International Technical Conference on Ci Vol.2015 No.6

        Recently, the performance of CPUs is improving by the technology of integrating circuits. By this improving, CPUs satisfies the demand which is needed for executing software on the computer. Therefore, CPUs aren’t always used fully. To use CPU more efficiently, the virtualization technology is used in various situations such as Web service, database service, cloud computing service, and so on. In this technology, users can integrate plural VMs (Virtual Machines) on one physical computer. However, when the number of processor cores is less than the number of VMs, the scheduler can’t concurrently allocate the CPU to all VMs. In this situation, each VM is allocated the CPU by the time sharing. Therefore, when all processor cores are allocated to other executions, the executable VM waits for allocating the CPU. This situation becomes the problem when the CPU is needed for real time processing on the VM, which is ready to execute. To solve this problem, we proposed Priority Control Method, which enables us to control allocating the CPU resources for each VM. Moreover, we evaluated the effectiveness of Priority Control Method by using the priority of the process before. However, we didn’t evaluate this method in Fedora 20 that is latest version of Fedora. Moreover, Fedora 20 has cgroups (Control Groups) that is the function of managing resources. Cgroups includes the function for the control of allocating the CPU to each VM. In this paper, we describe the effectiveness of Priority Control Method with KVM (Kernel-based Virtual Machine), which is one of methods for the virtualization of the computer. Moreover, we describe the evaluation that we tried to control allocating CPU for VMs by using cgroups in KVM.

      • Coupled thermo-hydro-mechanical-chemical modeling by incorporating pressure solution for estimating the evolution of rock permeability

        Yasuhara, Hideaki,Kinoshita, Naoki,Ogata, Sho,Cheon, Dae-Sung,Kishida, Kiyoshi Elsevier 2016 International journal of rock mechanics and mining Vol.86 No.-

        <P><B>Abstract</B></P> <P>A coupled THMC numerical model has been developed to examine the long-term change in permeability of the porous sedimentary rocks that are assumed to be composed purely of quartz. Specifically, the chemo-mechanical process of the pressure solution was incorporated into the model. The developed model was validated by replicating the existing experimental measurements of the porosity reduction and the evolving silica concentration. Subsequently, by simulating the burial of high-level radioactive wastes in the deep subsurface, namely, by applying the simulated confining pressure and temperature conditions, the long-term evolution of the rock permeability was predicted. The model predictions clearly showed a significant influence of the pressure dissolution on the change in permeability with time. The predicted permeability of the rocks close to the wastes decreased by one order of magnitude in 10<SUP>4</SUP> years when considering the pressure dissolution, while the permeability changed little during the same period when the pressure dissolution was not considered. This reduction should delay the dispersion of the radioactive materials dissolved in the groundwater.</P> <P><B>Highlights</B></P> <P> <UL> <LI> A coupled THMC numerical model was developed to predict the long-term change in permeability. </LI> <LI> The developed model considers the pressure solution. </LI> <LI> The model was validated by replicating the existing experiments. </LI> <LI> The model enables the evolution of rock permeability to be predicted under arbitrary pressure and temperature conditions. </LI> </UL> </P>

      • Modeling of coupled thermal-hydraulic-mechanical-chemical processes for predicting the evolution in permeability and reactive transport behavior within single rock fractures

        Ogata, Sho,Yasuhara, Hideaki,Kinoshita, Naoki,Cheon, Dae-Sung,Kishida, Kiyoshi Elsevier 2018 International journal of rock mechanics and mining Vol.107 No.-

        <P><B>Abstract</B></P> <P>A multi-physics numerical model was developed to predict the fluid flow and mass transport behavior of rock fractures under coupled thermal-hydraulic-mechanical-chemical (THMC) conditions. In particular, the model was employed for the purpose of describing the evolution of permeability and reactive transport behavior within rock fractures by taking into account the geochemical processes of the free-face dissolution and the pressure dissolution. In order to examine the capability of the developed model, the model was applied to replicate the experimental measurements of the evolution in hydraulic aperture, permeability, and element concentrations obtained from two flow-through experiments using single granite and mudstone fractures. The model predictions for the granite experiment were able to follow the actual data for the evolution in hydraulic aperture and effluent element concentrations without adopting any fitting parameters that are often used in other THMC coupled models obtained from literature. Furthermore, the model succeeded in replicating the actual changes in fracture permeability and effluent element concentrations within the mudstone fracture. Although some uncertain mismatches between the experiments and the model predictions, such as changes in the concentrations of several elements (i.e., Na and K concentrations in the granite fracture and Al in the mudstone fracture) were remaining at this stage, the developed model should be valid for evaluating the evolution in the fluid flow and mass transport behavior within rock fractures induced by mineral dissolution under stress- and temperature-controlled conditions.</P> <P><B>Highlights</B></P> <P> <UL> <LI> A coupled THMC numerical model was developed to predict changes in the permeability and reactive transport behavior within single rock fractures. </LI> <LI> The model was validated by replicating experimental measurements using granite and mudstone fractures. </LI> <LI> There were, however, some uncertain mismatches between the experiments and the model predictions in the concentrations of several elements. </LI> </UL> </P>

      • SCIESCOPUS

        Application of magnesium to improve uniform distribution of precipitated minerals in 1-m column specimens

        Putra, Heriansyah,Yasuhara, Hideaki,Kinoshita, Naoki,Hirata, Akira Techno-Press 2017 Geomechanics & engineering Vol.12 No.5

        This study discussed the possible optimization of enzyme-mediated calcite precipitation (EMCP) as a soil-improvement technique. Magnesium chloride was added to the injection solution to delay the reaction rate and to improve the homogenous distribution of precipitated minerals within soil sample. Soil specimens were prepared in 1-m PVC cylinders and treated with the obtained solutions composed of urease, urea, calcium, and magnesium chloride, and the mineral distribution within the sand specimens was examined. The effects of the precipitated minerals on the mechanical and hydraulic properties were evaluated by unconfined compressive strength (UCS) and permeability tests, respectively. The addition of magnesium was found to be effective in delaying the reaction rate by more than one hour. The uniform distribution of the precipitated minerals within a 1-m sand column was obtained when 0.1 mol/L and 0.4 mol/L of magnesium and calcium, respectively, were injected. The strength increased gradually as the mineral content was further increased. The permeability test results showed that the hydraulic conductivity was approximately constant in the presence of a 6% mineral mass. Thus, it was revealed that it is possible to control the strength of treated sand by adjusting the amount of precipitated minerals.

      • SCISCIESCOPUS

        Transfer kinetics of perfluorooctane sulfonate from water and sediment to a marine benthic fish, the marbled flounder ( <i>Pseudopleuronectes yokohamae</i> )

        Sakurai, Takeo,Kobayashi, Jun,Kinoshita, Kyoko,Ito, Nozomi,Serizawa, Shigeko,Shiraishi, Hiroaki,Lee, Jeong-Hoon,Horiguchi, Toshihiro,Maki, Hideaki,Mizukawa, Kaoruko,Imaizumi, Yoshitaka,Kawai, Toru,Suz Wiley Periodicals 2013 Environmental toxicology and chemistry Vol.32 No.9

        <P>The authors investigated the kinetics of transfer of perfluorooctane sulfonate (PFOS) from water, suspended sediment, and bottom sediment to a marine benthic fish, the marbled flounder (<I>Pseudopleuronectes yokohamae</I>). Fish were exposed in 3 treatments to PFOS in combinations of these exposure media for 28 d and then depurated for 84 d. A major part (37–66%) of PFOS in the fish was in the carcass (i.e., whole body minus muscle and internal organs). Three first-order-kinetic models that differed in exposure media, that is, 1) sum of dissolved and particulate phases and sediment; 2) dissolved phase, particulate phase, and sediment; and 3) dissolved phase only, were fitted to the data assuming common rate constants among the treatments. The uptake efficiency of dissolved PFOS at the respiratory surfaces was estimated to be 3.2% that of oxygen, and the half-life of PFOS in the whole body to be 29 d to 31 d. The better fit of models 1 and 2 and the values of the estimated uptake rate constants suggested that the PFOS in suspended and bottom sediments, in addition to that dissolved in water, contributed to the observed body burden of the fish. Based on an evaluation of several possible contributing factors to the uptake of PFOS from suspended and bottom sediments, the authors propose that further investigation is necessary regarding the mechanisms responsible for the uptake. <I>Environ Toxicol Chem</I> 2013;32:2009–2017. © 2013 The Authors. <I>Environmental Toxicology and Chemistry</I> Published by Wiley Periodicals, Inc., on behalf of SETAC. This is an open access article under the terms of the Creative Commons Attribution Non-Commercial License, which permits use, distribution, and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.</P>

      • Drilling force and speed for mandibular trabecular bone in oral implant surgery

        bin Kamisan, Mohammad Aimaduddin Atiq,Yokota, Kenichiro,Ueno, Takayuki,Kinoshita, Hideaki,Homma, Shinya,Yajima, Yasutomo,Abe, Shinichi,Takano, Naoki Techno-Press 2016 Biomaterials and biomedical engineering Vol.3 No.1

        Based on a survey done recently in Japan, 30 percent of the serious accidents occurred in oral implant surgery were concerned with the mandibular canal and 3/4 of them were related to drilling. One of the reasons lies in the lack of the education system. To overcome this problem, a new educational system focusing on drilling the mandibular trabecular bone has been developed mainly for dental college students in the form of an oral implant surgery training simulator that enables student to sense the reaction force during drilling. On the other hand, the conventional system uses polymeric model. Based on these systems, two approaches were proposed; the evaluation by experienced clinicians using the simulator, and experimental works on the polymeric model. Focusing on the combination of the drilling force sensed and drilling speed obtained through both approaches, the results were compared. It was found that the polymeric models were much softer especially near the mandibular canal. In addition, the study gave us an insight of the understanding in bone quality through tactile sensation of the drilling force and speed. Furthermore, the clinicians positively reviewed the simulator as a valid tool.

      • Drilling force and speed for mandibular trabecular bone in oral implant surgery

        bin Kamisan, Mohammad Aimaduddin Atiq,Yokota, Kenichiro,Ueno, Takayuki,Kinoshita, Hideaki,Homma, Shinya,Yajima, Yasutomo,Abe, Shinichi,Takano, Naoki Techno-Press 2016 Biomaterials and Biomechanics in Bioengineering Vol.3 No.1

        Based on a survey done recently in Japan, 30 percent of the serious accidents occurred in oral implant surgery were concerned with the mandibular canal and 3/4 of them were related to drilling. One of the reasons lies in the lack of the education system. To overcome this problem, a new educational system focusing on drilling the mandibular trabecular bone has been developed mainly for dental college students in the form of an oral implant surgery training simulator that enables student to sense the reaction force during drilling. On the other hand, the conventional system uses polymeric model. Based on these systems, two approaches were proposed; the evaluation by experienced clinicians using the simulator, and experimental works on the polymeric model. Focusing on the combination of the drilling force sensed and drilling speed obtained through both approaches, the results were compared. It was found that the polymeric models were much softer especially near the mandibular canal. In addition, the study gave us an insight of the understanding in bone quality through tactile sensation of the drilling force and speed. Furthermore, the clinicians positively reviewed the simulator as a valid tool.

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