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- 저자 : Hasson, Hasson M (검색결과 12 건)
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Hasson Denise C.,Mohan Shruthi,Rose James E.,Merrill Kyle A.,Goldstein Stuart L.,Benoit Stefanie W.,Varnell Charles D. 대한진단검사의학회 2024 Annals of Laboratory Medicine Vol.44 No.1
Background: Abnormal serum magnesium (Mg) concentrations are common and associated with worse mortality in kidney-transplant recipients. Many kidney and transplant-related factors affect Mg homeostasis. The concentration of the active form, ionized Mg (iMg), is not measured clinically, and total Mg (tMg) and iMg correlations have conflicted. We hypothesized that iMg and tMg concentrations show poor categorical agreement (i.e., low, normal, and high) in kidney-transplant recipients but that ionized calcium (iCa) correlates with iMg. Methods: We retrospectively evaluated hypomagnesemia in kidney-transplant recipients over a 2-yr period. We prospectively collected blood at 0–28 days post-transplant to measure correlations between iMg and iCa/tMg. iMg and iCa concentrations in the reference ranges of 0.44–0.65 and 1.0–1.3 mmol/L, respectively, were considered normal. Fisher’s exact test and unweighted kappa statistics revealed category agreements. Pearson’s correlation coefficients and linear regression measured correlations. Results: Among 58 retrospective kidney-transplant recipients, 54 (93%) had tMg<0.66 mmol/L, 28/58 (48%) received Mg supplementation, and 20/28 (71%) had tacrolimus dose adjustments during supplementation. In 13 prospective transplant recipients (N=43 samples), iMg and tMg showed strong category agreement (P=0.0003) and correlation (r=0.71, P<0.001), whereas iMg and iCa did not (P=0.7; r=–0.25, P=0.103, respectively). Conclusions: tMg and iMg exhibited strong correlation following kidney transplantation. However, iCa may not be an accurate surrogate for iMg. Determining the effect of Mg supplementation and the Mg concentration where supplementation is clinically necessary are important next steps.
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Hasson, Sidgi S.A.A,Al-Busaidi, Juma Zaid,Al-Qarni, Zahra A.M.,Rajapakse, S.,Al-Bahlani, Shadia,Idris, Mohamed Ahmed,Sallam, Talal A. Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.15
Breast cancer is a global health concern and is a major cause of death among women. In Oman, it is the most common cancer in women, with an incidence rate of 15.6 per 100,000 Omani females. Various anticancer remedies have been discovered from natural products in the past and the search is continuing for additional examples. Cytotoxic natural compounds may have a major role in cancer therapy either in potentiating the effect of chemotherapy or reducing its harmful effects. Recently, a few studies have reported advantages of using crude camel milk in treating some forms of cancer. However, no adequate data are available on the lyophilised camel's milk responsibility for triggering apoptosis and oxidative stress associated with human breast cancer. The present study aimed to address the role of the lyophilised camel's milk in inducing proliferation repression of BT-474 and HEp-2 cells compared with the non-cancer HCC1937 BL cell line. Lyophilized camel's milk fundamentally repressed BT-474 cells growth and proliferation through the initiation of either the intrinsic and extrinsic apoptotic pathways as indicated by both caspase-3 mRNA and its action level, and induction of death receptors in BT-474 but not the HEp-2 cell line. In addition, lyophilised camel's milk enhanced the expression of oxidative stress markers, heme-oxygenase-1 and reactive oxygen species production in BT-474 cells. Increase in caspase-3 mRNA levels by the lyophilised camel's milk was completely prevented by the actinomycin D, a transcriptional inhibitor. This suggests that lyophilized camel's milk increased newly synthesized RNA. Interestingly,it significantly (p<0.003) repressed the growth of HEp-2 cells and BT-474 cells after treatment for 72 hours while 24 hours treatment repressed BT-474 cells alone. This finding suggests that the lyophilised camel's milk might instigate apoptosis through initiation of an alternative apoptotic pathway.
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Epidemiology of Breast Cancer among Females in Basrah
Habib, Omran S,Hameed, Lamis A,Ajeel, Narjis A,Al-Hawaz, Mazin H,Al-Faddagh, Zaki A,Nasr, Ghalib N,Al-Sodani, Ali H,Khalaf, Asaad A,Hasson, Hasson M,Abdul-Samad, Aida A Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.no.sup3
Breast cancer is the most frequent cancer in females. Its incidence is higher in developed countries than in developing ones partly due to variation in risk exposure and partly due to better detection methods. Scattered evidence in Basrah, Iraq, suggests that breast cancer has been increasing at a significant pace in recent years. This study aimed to measure the current level of risk of breast cancer among females in Basrah and to describe the time trend over almost a decade of years. Data on breast cancer cases from all sources of cancer registration in Basrah governorate were compiled for the years 2005-2012. The data for each year were first checked separately for duplicate reporting of cases among various sources. Then the eight files were pooled together and checked again for any duplicate cases among years of registration. The final set of data contained 2,284 cases of breast cancer (2,213 female cases and 71 male cases). All patients were inhabitants of Basrah governorate at the time of diagnosis. Figures on the Basrah population were obtained from various sources including the Ministry of Health, Ministry of Planning and Developmental Collaboration and local household surveys. It was possible to have total population estimates for each year and by age and sex. The data were imported into SPSS (version 17) software. Age specific and year specific incidence rates were calculated. The age standardized incidence rate was also calculated using world population as the standard population to be 34.9 per 100,000 females. Age-wise, no case was reported among children aged less than 15 years and the incidence increased with advancing age reaching a peak of 123.8/100,000 females at the age range of 50-54 years. The time trend of the crude incidence rate showed only modest increased risk with passage of years and no age shift could be documented in this study. Breast cancer in females in Basrah is a significant health problem. The current incidence rate (crude, 23.7/100,000, age-standardized, 34.9/100,000) is high and justifies intensive efforts to improve early detection of cases, provide better treatment amenities and introduce long term preventive measures. Using the age standardized incidence rate as reported in this paper, it is possible to put the risk in Basrah within a regional and international context.
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Free vibration analysis of cantilever cylindrical tanks
Hadid, H.A.,Hasson, D.A. Techno-Press 1995 Structural Engineering and Mechanics, An Int'l Jou Vol.3 No.1
General free vibration characteristics of cantilevered circular cylindrical tanks are analyzed using the integral equations technique with the cubic spline functions. For computations, the partial differential equations for thin shallow shells as given by Flugge's have been employed after the addition of the inertia forces. The application of the method is illustrated with a numerical examples of tanks which are free at the top edge and fixed at the bottom. The results obtained by this method have been compared with the available results and a good agreement was found.
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Zarrin Milad,Nakhostin Ansari Noureddin,Naghdi Soofia,Hasson Scott,Forogh Bijan,Rezaee Mehdi 사단법인약침학회 2023 Journal of Acupuncture & Meridian Studies Vol.16 No.5
Background: Dry needling (DN) is recommended as a therapeutic modality for various neuromusculoskeletal disorders. No study has been performed on the impact of DN on arthrogenic muscle inhibition (AMI) after anterior cruciate ligament reconstruction (ACLR). This study protocol is aimed to investigate the impacts of DN on AMI of quadriceps femoris, corticomotor, and spinal reflex excitability in patients with ACLR. Methods: A double-blind, between-subject, randomized, controlled trial will be conducted to measure changes in AMI after DN. Twenty-four subjects with ACLR will be recruited to receive a DN or a sham DN, providing that they met the inclusion criteria. Three sessions of DN on the quadriceps femoris will be applied during a one-week period. The primary outcome measures are the active motor threshold, motor evoked potential, and Hmax – Mmax ratio. The secondary outcomes are the International Knee Documentation Committee subjective knee form questionnaire score and maximum quadriceps isometric torque. Data will be collected at baseline, immediately after the first session, after the third session, and at the one-month follow-up visit. Discussion: The results of this study will provide preliminary evidence regarding the effects of DN on AMI of quadriceps femoris in patients with ACLR.
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Leading for Safety: A Question of Leadership Focus
Molnar, Malin Mattson,Schwarz, Ulrica Von Thiele,Hellgren, Johnny,Hasson, Henna,Tafvelin, Susanne Occupational Safety and Health Research Institute 2019 Safety and health at work Vol.10 No.2
Background: There is considerable evidence that leadership influences workplace safety, but less is known about the relative importance of different leadership styles for safety. In addition, a leadership style characterized by an emphasis and a focus on promoting safety has rarely been investigated alongside other more general leadership styles. Methods: Data were collected through a survey to which 269 employees in a paper mill company responded. A regression analysis was conducted to examine the relative roles of transformational, transactional (management-by-exception active; MBEA), and safety-specific leadership for different safety behavioral outcomes (compliance behavior and safety initiative behaviors) and for minor and major injuries. Results: A safety-specific leadership contributed the most to the enhanced safety of the three different kinds of leadership. Transformational leadership did not contribute to any safety outcome over and above that of a safety-specific leadership, whereas a transactional leadership (MBEA) was associated with negative safety outcomes (fewer safety initiatives and increased minor injuries). Conclusion: The most important thing for leaders aiming at improving workplace safety is to continuously emphasize safety, both in their communication and by acting as role models. This highlights the importance for leadership training programs aiming to improve safety to actually focus on safety-promoting communication and behaviors rather than general leadership. Furthermore, an overly monitoring and controlling leadership style can be detrimental to attempts at achieving improved workplace safety.
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CFRP strengthening of continuous RC T-beams at hogging moment zone across the flange
Mohammad Mohie Eldin,Ahmed M. Tarabia,Rahma F. Hasson 국제구조공학회 2017 Structural Engineering and Mechanics, An Int'l Jou Vol.64 No.6
Carbon Fiber Reinforced Polymer (CFRP) laminates are used widely either for repairing or strengthening of existing structures. When CFRP laminates are used for strengthening of RC continuous T-beams in the Hogging Moment Zone (HMZ); above and around the intermediate supports, it is important to study the expected positions of the laminates across the width of the beam flange. Although, it is traditional to consider CFRP laminates added above the beam web, this is not practical since walls and columns are located in such positions in general. This paper examines the effect of changing the positions of CFRP laminates used for the strengthening of the hogging moment zone across the beam flange of two-span-T-section beams. The Finite Element (FE) Package ANSYS is used to create 3-D theoretical models needed for the study. It can be concluded that changing the position of CFRP strengthening across the beam flange, in the hogging moment zone, is effective upon the overall behavior. The best locations are either above the web or at the flange just beside the web, due to the presence of walls and/or columns.
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Leading for Safety: A Question of Leadership Focus
Malin Mattson Molnar,Ulrica Von Thiele Schwarz,Johnny Hellgren,Henna Hasson,Susanne Tafvelin 한국산업안전보건공단 산업안전보건연구원 2019 Safety and health at work Vol.10 No.2
Background: There is considerable evidence that leadership influences workplace safety, but less is known about the relative importance of different leadership styles for safety. In addition, a leadership style characterized by an emphasis and a focus on promoting safety has rarely been investigated alongside other more general leadership styles. Methods: Data were collected through a survey to which 269 employees in a paper mill company responded. A regression analysis was conducted to examine the relative roles of transformational, transactional (management-by-exception active; MBEA), and safety-specific leadership for different safety behavioral outcomes (compliance behavior and safety initiative behaviors) and for minor and major injuries. Results: A safety-specific leadership contributed the most to the enhanced safety of the three different kinds of leadership. Transformational leadership did not contribute to any safety outcome over and above that of a safety-specific leadership, whereas a transactional leadership (MBEA) was associated with negative safety outcomes (fewer safety initiatives and increased minor injuries). Conclusion: The most important thing for leaders aiming at improving workplace safety is to continuously emphasize safety, both in their communication and by acting as role models. This highlights the importance for leadership training programs aiming to improve safety to actually focus on safety-promoting communication and behaviors rather than general leadership. Furthermore, an overly monitoring and controlling leadership style can be detrimental to attempts at achieving improved workplace safety.
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