Survey of research on the optimal design of sea harbours

Hassan Diab,Rafic Younes,Pascal Lafon 대한조선학회 2017 International Journal of Naval Architecture and Oc Vol.9 No.4

The design of harbours, as with any other system design, must be an optimization process. In this study, a global examination of the different constraints in coastal engineering was performed and an optimization problem was defined. The problem has multiple objectives, and the criteria to be minimized are the structure cost and wave height disturbance inside a harbour. As concluded in this survey, the constraints are predefined parameters, mandatory constraints or optional constraints. All of these constraints are categorized into four categories: environmental, fluid mechanical, structural and manoeuvring.

Serum Talin-1 is a Potential Novel Biomarker for Diagnosis of Hepatocellular Carcinoma in Egyptian Patients

Youns, Mahmoud M.,Abdel Wahab, Abdel Hady A.,Hassan, Zeinab A.,Attia, Mohamed S. Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.6

Background: Hepatocellular carcinoma (HCC) is a major cause of cancer mortality worldwide. The outcome of HCC depends mainly on its early diagnosis. To date, the performance of traditional biomarkers is unsatisfactory. Talins were firstly identified as cytoplasmic protein partners of integrins but Talin-1 appears to play a crucial role in cancer formation and progression. Our study was conducted to assess the diagnostic value of serum Talin-1 (TLN1) compared to the most feasible traditional biomarker alpha-fetoprotein (AFP) for the diagnosis of HCC. Methods: TLN1 was detected using enzyme linked immunosorbent assay (ELISA) in serum samples from 120 Egyptian subjects including 40 with HCC, 40 with liver cirrhosis (LC) and 40 healthy controls (HC). Results: ROC curve analysis was used to create a predictive model for TLN1 relative to AFP in HCC diagnosis. Serum levels of TLN1 in hepatocellular carcinoma patients were significantly higher compared to the other groups (p<0.0001). The diagnostic accuracy of TLN1 was higher than that of AFP regarding sensitivity, specificity, positive predictive value and negative predictive value in diagnosis of HCC. Conclusions: The present study showed for the first time that Talin-1 (TLN1) is a potential diagnostic marker for HCC, with a higher sensitivity and specificity compared to the traditional biomarker AFP.

Survey of research on the optimal design of sea harbours

Diab, Hassan,Younes, Rafic,Lafon, Pascal The Society of Naval Architects of Korea 2017 International Journal of Naval Architecture and Oc Vol.9 No.4

The design of harbours, as with any other system design, must be an optimization process. In this study, a global examination of the different constraints in coastal engineering was performed and an optimization problem was defined. The problem has multiple objectives, and the criteria to be minimized are the structure cost and wave height disturbance inside a harbour. As concluded in this survey, the constraints are predefined parameters, mandatory constraints or optional constraints. All of these constraints are categorized into four categories: environmental, fluid mechanical, structural and manoeuvring.

Integrating approach to size and site at a sanitary landfill in Selangor state, Malaysia

Mohammad Khairi Younes,Noor Ezlin Ahmad Basri,Zulkifli Mohammad Nopiaha,Hassan Basri,Mohammed F. M. Abushammala,Khairul Nizam Abdul Maulud 대한환경공학회 2015 Environmental Engineering Research Vol.20 No.3

Solid waste production increases due to population and consumption increments. Landfill is the ultimate destination for all kinds of municipal solid waste; and is the most convenient waste disposal method in developing countries. To minimize investment and operational costs and society’s opposition towards locating landfills nearby, proper landfill sizing and siting are essential. In this study, solid waste forecasting using Autoregressive Integrating Moving Average (ARIMA) was integrated with government future plans and waste composition to estimate the required landfill area for the state of Selangor, Malaysia. Landfill siting criteria were then prioritized based on expert’s preferences. To minimize ambiguity and the uncertainty of the criteria prioritizing process, the expert’s preferences were treated using integrated Median Ranked Sample Set (MRSS) and Analytic Hierarchy Process (AHP) models. The results show that the required landfill area is 342 hectares and the environmental criteria are the most important; with a priority equal to 48%.

Analysis of a Generalized ZVD Shaper Using Impulse Vectors

Chul-Goo Kang,Rubayet Hassan,Kyung-Youn Kim 제어·로봇·시스템학회 2020 International Journal of Control, Automation, and Vol.18 No.8

Recently, an impulse vector was introduced as an effective mathematical tool to design and analyze input shapers. In this paper, we generalize the ZV (zero vibration) and ZVD (zero vibration and derivative) shapers by using impulse vectors. The proposed generalized ZVD shaper is defined by letting the ratio m of the third impulse vector magnitude to the first impulse vector magnitude in the impulse vector diagram to be variable. Then two extreme cases of the generalized ZVD shaper are the ZV and ZVD shaper when m = 0 and m = 1, respectively. The generalized ZVD shaper has the performance between ZV and ZVD shaper performance in view of robustness to modeling errors. The validity of the proposed generalized ZVD shaper is demonstrated by simulation and experimental works using an up-and-down flexible beam device.

Adaptogenic effects of Panax ginseng on modulation of immune functions

Zubair Ahmed Ratan,Soo Hyun Youn,Yi-Seong Kwak,Chang-Kyun Han,Mohammad Faisal Haidere,Jin Kyeong Kim,Hyeyoung Min,You-Jung Jung,Hassan Hosseinzadeh,Sun Hee Hyun,Jae Youl Cho 고려인삼학회 2021 Journal of Ginseng Research Vol.45 No.1

Traditional medicinal practices have used natural products such as adaptogens to treat inflammatory, autoimmune, neurodegenerative, bacterial, and viral diseases since the early days of civilization. Panax ginseng Myer is a common herb used in East Asian countries for millennia, especially in Korea, China, and Japan. Numerous studies indicate that ginseng can modulate the immune system and thereby prevent diseases. Although the human immune system comprises many different types of cells, multiple studies suggest that each type of immune cell can be controlled or stimulated by ginseng or its derivatives. Provisional lists of ginseng’s potential for use against viruses, bacteria, and other microorganisms suggest it may prove to be a valuable pharmaceutical resource, particularly if higher-quality evidence can be found. Here, we reviewed the role of ginseng as an immune-modulating agent in attempt to provide a valuable starting point for future studies on the herb and the human immune system.

Characteristics of nonalcoholic fatty liver disease induced in wistar rats following four different diets

Nicole Fakhoury-Sayegh,Viviane Trak-Smayra,Aline Khazzaka,Fady Esseily,Omar Obeid,May Lahoud-Zouein,Hassan Younes 대한지역사회영양학회 2015 Nutrition Research and Practice Vol.5 No.6

BACKGROUND/OBJECTIVES: The prevalence of nonalcoholic fatty liver disease (NAFLD) has increased worldwide in parallel with overnutrition characterized by high-fat and high-carbohydrate intake. Our objective was to establish, in 16 weeks, a model of NAFLD in Wistar pathogen-free rats following four dietary types. MATERIALS/METHODS: Forty (6 weeks old) healthy Wistar male rats, weighing an average of 150 g were randomly divided into four groups of ten and assigned a diet with the same quantity (15 g/rat/day), but with different composition. The moderate-fat (MF) group was fed a moderate-fat diet (31.5% fat and 50% carbohydrates), the high-fat (HF) group was fed a fat-rich diet (51% fat), the high-sucrose (HS) group and the high-fructose (HFr) group were fed a carbohydrate-rich diet (61%). The carbohydrate contents of the HS group was composed of 60.3% sucrose while that of the HFr group was composed of 59.3% fructose. RESULTS: At week 16, the HF group had the highest percentage of cells enriched in fat (40%) and the highest weight and liver weight (P < 0.05). The HFr group showed significantly higher levels of serum triglycerides, alanine aminotransferase and adiponectin at week 16 as compared to week 1 (P < 0.05). CONCLUSIONS: The 15 g/rat/day diet composed of 51% fat or 61% carbohydrates enriched mainly in fructose may induce characteristics of NAFLD in rats.

Characteristics of nonalcoholic fatty liver disease induced in wistar rats following four different diets

Fakhoury-Sayegh, Nicole,Trak-Smayra, Viviane,Khazzaka, Aline,Esseily, Fady,Obeid, Omar,Lahoud-Zouein, May,Younes, Hassan The Korean Nutrition Society 2015 Nutrition Research and Practice Vol.9 No.4

BACKGROUND/OBJECTIVES: The prevalence of nonalcoholic fatty liver disease (NAFLD) has increased worldwide in parallel with overnutrition characterized by high-fat and high-carbohydrate intake. Our objective was to establish, in 16 weeks, a model of NAFLD in Wistar pathogen-free rats following four dietary types. MATERIALS/METHODS: Forty (6 weeks old) healthy Wistar male rats, weighing an average of 150 g were randomly divided into four groups of ten and assigned a diet with the same quantity (15 g/rat/day), but with different composition. The moderate-fat (MF) group was fed a moderate-fat diet (31.5% fat and 50% carbohydrates), the high-fat (HF) group was fed a fat-rich diet (51% fat), the high-sucrose (HS) group and the high-fructose (HFr) group were fed a carbohydrate-rich diet (61%). The carbohydrate contents of the HS group was composed of 60.3% sucrose while that of the HFr group was composed of 59.3% fructose. RESULTS: At week 16, the HF group had the highest percentage of cells enriched in fat (40%) and the highest weight and liver weight (P < 0.05). The HFr group showed significantly higher levels of serum triglycerides, alanine aminotransferase and adiponectin at week 16 as compared to week 1 (P < 0.05). CONCLUSIONS: The 15 g/rat/day diet composed of 51% fat or 61% carbohydrates enriched mainly in fructose may induce characteristics of NAFLD in rats.

Characteristics of nonalcoholic fatty liver disease induced in wistar rats following four different diets

Nicole Fakhoury-Sayegh,Viviane Trak-Smayra,Aline Khazzaka,Fady Esseily,Omar Obeid,May Lahoud-Zouein,Hassan Younes 한국영양학회 2015 Nutrition Research and Practice Vol.9 No.4

BACKGROUND/OBJECTIVES: The prevalence of nonalcoholic fatty liver disease (NAFLD) has increased worldwide in parallel with overnutrition characterized by high-fat and high-carbohydrate intake. Our objective was to establish, in 16 weeks, a model of NAFLD in Wistar pathogen-free rats following four dietary types. MATERIALS/METHODS: Forty (6 weeks old) healthy Wistar male rats, weighing an average of 150 g were randomly divided into four groups of ten and assigned a diet with the same quantity (15 g/rat/day), but with different composition. The moderate-fat (MF) group was fed a moderate-fat diet (31.5% fat and 50% carbohydrates), the high-fat (HF) group was fed a fat-rich diet (51% fat), the high-sucrose (HS) group and the high-fructose (HFr) group were fed a carbohydrate-rich diet (61%). The carbohydrate contents of the HS group was composed of 60.3% sucrose while that of the HFr group was composed of 59.3% fructose. RESULTS: At week 16, the HF group had the highest percentage of cells enriched in fat (40%) and the highest weight and liver weight (P < 0.05). The HFr group showed significantly higher levels of serum triglycerides, alanine aminotransferase and adiponectin at week 16 as compared to week 1 (P < 0.05). CONCLUSIONS: The 15 g/rat/day diet composed of 51% fat or 61% carbohydrates enriched mainly in fructose may induce characteristics of NAFLD in rats.