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      • KCI등재

        Effects of Intravesical Electrical Stimulation on Urinary Adenosine Triphosphate and Nitric Oxide in Rats With Detrusor Underactivity Induced By Bilateral Pelvic Nerve Crush Injury: The Possible Underlying Mechanism

        Han Deng,Limin Liao,Xing Li,Qinggang Liu,Xuesheng Wang,Zhonghan Zhou 대한배뇨장애요실금학회 2022 International Neurourology Journal Vol.26 No.4

        Purpose: To explore the effect of intravesical electrical stimulation (IVES) on urinary adenosine triphosphate (ATP) and nitric oxide (NO) in rats with detrusor underactivity (DU) induced by bilateral pelvic nerve crush (bPNC), and to determine the underlying peripheral mechanism. Methods: Twenty-four female Sprague-Dawley rats were equally divided into 3 groups: sham; bPNC; and IVES. Rats in the IVES group began to receive IVES treatment 10 days after bPNC (20 minutes per day for 14 consecutive days). After the 14th IVES, rat urine was collected and cystometry was performed. The serum creatinine, blood urea nitrogen, and urinary ATP and NO levels were measured, and a routine urinalysis was performed. Results: The maximum cystometric capacity (MCC), maximum changes in bladder pressure during filling (∆FP), and postvoid residual urine (PVR) in the IVES group were significantly lower than the bPNC group, and the maximum changes in bladder pressure during voiding (∆VP) was significantly higher than the bPNC group. Compared with the sham group, the MCC, ∆FP and PVR were significantly increased, and the maximum voiding pressure (MVP) and ∆VP were significantly decreased in the bPNC group. After bPNC, urinary ATP was significantly decreased, and urinary NO was significantly increased. In IVES-treated rats, urinary ATP was significantly higher than the bPNC group, and NO was significantly lower than the bPNC group. In addition, the ATP-to-NO ratio of the rats in the bPNC group was significantly lower than the sham and IVES groups. Correlation analysis showed that the ATP and NO were not correlated with the MCC, ∆FP, MVP, ∆VP, and PVR. Conclusions: Promoting the release of urothelial ATP and inhibiting the release of urothelial NO may be one of the peripheral mechanisms underlying IVES in the treatment of DU. Specifically, IVES may shift the balance between excitation and inhibition toward excitation

      • KCI등재

        Risk Factors Predicting Upper Urinary Tract Damage in Patients With Myelodysplasia: Data Analysis of 637 Cases From A Single Center

        Han Deng,Zhaoxia Wang,Limin Liao,Juan Wu,Yue Wang 대한배뇨장애요실금학회 2022 International Neurourology Journal Vol.26 No.S1

        Purpose: To determine the risk factors predicting upper urinary tract (UUT) damage using a grading system for upper urinary tract dilation (UUTD) and a descriptive system for all urinary tract dysfunction (AUTD) in patients with myelodysplasia. Methods: Six hundred thirty-seven patients with myelodysplasia were evaluated at our center from January 2008 to November 2019. Clinical data, ultrasonography, magnetic resonance urography, and video-urodynamics (VUDS) parameters were collected. Univariate and multivariate analyses were used to determine the risk factors predicting UUT damage. Results: Three hundred eighty-three males and 254 females were included. The average course of lower urinary tract symptoms (LUTS) was 14.08±7.07 years (range, 3–31 years). The urodynamic diagnoses of all patients were as follows: detrusor overactivity, 26.8%; detrusor underactivity, 6.44%; and acontractile detrusor, 66.72%. UUT damage was determined in 66.56% of the patients. Of the patients, 28.73 % had vesicoureteral reflux (VUR) during filling (bilateral, n=50; unilateral, n=133) on fluoroscopy during VUDS testing. Two hundred thirty-four patients had UUTD (bilateral, n=203; unilateral, n=31). The occurrence of hydronephrosis based on ultrasonography was closely related to ipsilateral VUR (P<0.05). Absent of bladder sensation, long-term course of LUTS, decreased maximum cystometric capacity (MCC) and bladder compliance (BC), and increased postvoid residual urine (PVR) were shown to be independent risk factors in logistic regression analysis. Conclusions: This retrospective study using UUTD and AUTD systems indicated that patients with myelodysplasia have a high incidence of UUT damage. Absence of bladder sensation, long-term course of LUTS, decreased MCC and BC, and increased PVR were independent risk factors predicting UUT damage.

      • SCIESCOPUS

        Analysis of thermally induced vibration of cable-beam structures

        Deng, Han-Qing,Li, Tuan-Jie,Xue, Bi-Jie,Wang, Zuo-Wei Techno-Press 2015 Structural Engineering and Mechanics, An Int'l Jou Vol.53 No.3

        Cable-beam structures characterized by variable stiffness nonlinearities are widely found in various structural engineering applications, for example in space deployable structures. Space deployable structures in orbit experience both high temperature caused by sun's radiation and low temperature by Earth's umbral shadow. The space temperature difference is above 300K at the moment of exiting or entering Earth's umbral shadow, which results in structural thermally induced vibration. To understand the thermally induced oscillations, the analytical expression of Boley parameter of cable-beam structures is firstly deduced. Then, the thermally induced vibration of cable-beam structures is analyzed using finite element method to verify the effectiveness of Boley parameter. Finally, by analyzing the obtained numerical results and the corresponding Boley parameters, it can be concluded that the derived expression of Boley parameter is valid to evaluate the occurrence conditions of thermally induced vibration of cable-beam structures and the key parameters influencing structural thermal flutter are the cable stiffness and thickness of beams.

      • KCI등재

        Analysis of thermally induced vibration of cable-beam structures

        Han-Qing Deng,Tuan-Jie Li,Bi-Jie Xue,Zuo-Wei Wang 국제구조공학회 2015 Structural Engineering and Mechanics, An Int'l Jou Vol.53 No.3

        Cable-beam structures characterized by variable stiffness nonlinearities are widely found in various structural engineering applications, for example in space deployable structures. Space deployablestructures in orbit experience both high temperature caused by sun’s radiation and low temperature by Earth’s umbral shadow. The space temperature difference is above 300K at the moment of exiting or entering Earth’s umbral shadow, which results in structural thermally induced vibration. To understand the thermally induced oscillations, the analytical expression of Boley parameter of cable-beam structures is firstly deduced. Then, the thermally induced vibration of cable-beam structures is analyzed using finite element method to verify the effectiveness of Boley parameter. Finally, by analyzing the obtained numerical results and the corresponding Boley parameters, it can be concluded that the derived expression of Boley parameter is valid to evaluate the occurrence conditions of thermally induced vibration of cable-beam structures and the key parameters influencing structural thermal flutter are the cable stiffness and thickness of beams.

      • Incorporating price preferences for product recommendation in electronic commerce

        Han Chen,Weiwei Deng 한국지능정보시스템학회 2022 한국지능정보시스템학회 학술대회논문집 Vol.2022 No.6

        Product recommendation methods have become the cornerstone of electronic commerce platforms due to their ability to solve the information overload problem and inform customers about their potentially interesting products. However, previous recommendation methods fail to consider customers’ price preferences, which are essential in recommending suitable products. To bridge this gap, this study proposes a hybrid recommendation method that combines customer behaviors, product content, and price preferences for product recommendations. In the proposed method, two strategies are designed to model customers’ price preferences. The proposed method is evaluated with a real-world data set and compared with three baseline methods. The evaluation results show that the proposed recommendation method with either strategy significantly outperforms the three baseline methods in terms of precision, recall. F-score, and mean average precision (MAP) measures.

      • KCI등재

        Does vegetation matter for the criminal behavior among people with serious mental illness?

        Han Woojae,Marzell Miesha,Deng Chengbin 한국사회복지학회 2020 Asian Social Work and Policy Review Vol.14 No.1

        This study attempts to examine the effect of vegetation on arrests of offenders with and without serious mental illness (SMI). Data from the MacArthur mental health court study were analyzed. Objective arrest data were obtained 12–18 months preand post‐court involvement between 2005 and 2007. Vegetation data were captured by the normalized difference vegetation index, which can be regarded as a general measure of “vegetation” and linked with GeoID, obtained from the American Community Survey. We analyzed data of sociodemographic factors (e.g., age, gender), crime‐related factors (e.g., age of first arrest), and vegetation in related to the crime on 652 offenders with mental illness. Multilevel negative binomial regression revealed no significant effect of vegetation on arrests among offenders without SMI; however, for those with SMI, a significant variation in vegetation on arrests was found among all study models. Our findings suggest that vegetation is significantly associated with arrests, with a positive effect on reducing the recidivism only among offenders with SMI. Given that practice and policy almost exclusively focus on individual factors of crimes, it is important to have more considerations about how neighborhood factors affect criminal behavior, depending on SMI in order to have more comprehensive methods of crime prevention.

      • SCOPUS

        A Novel Hybrid Intelligence Algorithm for Solving Combinatorial Optimization Problems

        Deng, Wu,Chen, Han,Li, He Korean Institute of Information Scientists and Eng 2014 Journal of Computing Science and Engineering Vol.8 No.4

        The ant colony optimization (ACO) algorithm is a new heuristic algorithm that offers good robustness and searching ability. With in-depth exploration, the ACO algorithm exhibits slow convergence speed, and yields local optimization solutions. Based on analysis of the ACO algorithm and the genetic algorithm, we propose a novel hybrid genetic ant colony optimization (NHGAO) algorithm that integrates multi-population strategy, collaborative strategy, genetic strategy, and ant colony strategy, to avoid the premature phenomenon, dynamically balance the global search ability and local search ability, and accelerate the convergence speed. We select the traveling salesman problem to demonstrate the validity and feasibility of the NHGAO algorithm for solving complex optimization problems. The simulation experiment results show that the proposed NHGAO algorithm can obtain the global optimal solution, achieve self-adaptive control parameters, and avoid the phenomena of stagnation and prematurity.

      • KCI등재

        Prognostic value of preoperative neutrophil-to-lymphocyte ratio in histological variants of non-muscle-invasive bladder cancer

        Deng-xiong Li,Xiao-ming Wang,Yin Tang,Yu-bo Yang,Dechao Feng,Ao Li,Fa-cai Zhang,Yun-jin Bai,Ping Han 대한비뇨의학회 2021 Investigative and Clinical Urology Vol.62 No.6

        Purpose: Many studies identified that the preoperative neutrophil-to-lymphocyte ratio (PNLR) was associated with patient prognosis in non-muscle-invasive bladder cancer (NMIBC). We hypothesized that PNLR could be prognostic in patients with histological variants of NMIBC (VH-NMIBC). Materials and Methods: This retrospective study included patients with VH-NMIBC admitted at our center between January 2009 and May 2019. The best cut-off value of NLR was measured by the receiver operating characteristic curve and Youden index. The Kaplan-Meier method and Cox proportional hazard regression models were employed to evaluate the association between PNLR and disease prognosis, including recurrence-free survival (RFS), progression-free survival (PFS), cancer-specific survival (CSS), and overall survival (OS). Results: A total of 243 patients with VH-NMIBC were enrolled in our study. According to the Kaplan-Meier method results, patients with PNLR ≥2.2 were associated with poor RFS (p<0.001), PFS (p<0.001), CSS (p<0.001), and OS (p<0.001). Multivariable analyses indicated that PNLR ≥ 2.2 was an independent prognostic factor of RFS (hazard ratio [HR], 2.11; 95% confidence interval [CI, 1.57–1.83; p<0.001), PFS (HR, 2.34; 95% CI, 1.70–3.21; p<0.001), CCS (HR, 2.87; 95% CI, 1.96–4.18; p< 0.001), and OS (HR, 2.83; 95% CI, 1.96–4.07; p<0.001). Conclusions: This study identified that PNLR ≥2.2 was usually associated with a poor prognosis for patients with VH-NMIBC.

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