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      • KCI등재

        Braking performance and noise in excessive worn brake discs coated with HVOF thermal spray process

        Ali Öz,Habib Gürbüz,Ali Kemal Yakut,Selami Sağiroğlu 대한기계학회 2017 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.31 No.2

        In this paper, two excessive worn brake discs of a light commercial vehicle were coated with High velocity oxygen fuel (HVOF) thermal spray process for reuse. The coated discs were compared with uncoated Original equipment manufacturer (OEM) D1 disc in terms of braking performance and noise. The D2 disc was coated with tungsten-carbide-cobalt (88 %WC-12 %Co) powder and NiCr (80/20) binder, and 500 µm thick coating was obtained. The D3 disc was coated with Colmonoy-88 (Ni-W-Cr-B-Si) powder and NiCr (80/20) binder and 600 µm thick coating was obtained. Several test procedures (e.g. bedding, vibration, and structural-strength tests) was applied to three discs using inertia brake dynamometer. Results showed that coated D2 disc with tungsten carbide cobalt provided lower brake noise and higher brake performance compared with OEM disc. Considering the coefficient of friction and temperature, coated D3 disc has approximately equal braking performance with OEM D1 disc despite the high braking noise value.

      • KCI등재

        PROBING GALAXY FORMATION MODELS IN COSMOLOGICAL SIMULATIONS WITH OBSERVATIONS OF GALAXY GROUPS

        HABIB. G., KHOSROSHAHI,GOZALIASL, GHASSEM,FINOGUENOV, ALEXIS,RAOUF, MOJTABA,MIRAGHEE, HALIME The Korean Astronomical Society 2015 天文學論叢 Vol.30 No.2

        We use multi-wavelength observations of galaxy groups to probe the formation models for galaxy formation in cosmological simulations, statistically. The observations include Chandra and XMM-Newton X-ray observations, optical photometry and radio observations at 1.4 GHz and 610 MHz. Using a large sample of galaxy groups observed by the XMM-Newton X-ray telescope as part of the XMM-Large Scale Survey, we carried out a statistical study of the redshift evolution of the luminosity gap for a well defined mass-selected group sample and show the relative success of some of the semi-analytic models in reproducing the observed properties of galaxy groups up to redshift z ~ 1.2. The observed trend argues in favour of a stronger evolution of the feedback from active galactic nuclei at z < 1 compared to the models. The slope of the relation between the magnitude of the brightest cluster galaxy and the value of the luminosity gap does not evolve with redshift and is well reproduced by the models. We find that the radio power of giant elliptic galaxies residing in galaxy groups with a large luminosity gap are lower compared to giant ellipticals of the same stellar masses but in typical galaxy groups.

      • An improved method for the derivation of high quality iPSCs in the absence of c-Myc

        Habib, O.,Habib, G.,Choi, H.W.,Hong, K.S.,Tae Do, J.,Moon, S.H.,Chung, H.M. Academic Press 2013 Experimental cell research Vol.319 No.20

        Induced pluripotent stem cells (iPSCs) hold tremendous potential for the development of new regenerative medicine therapies and the study of molecular mechanisms of pluripotency and development. However, reactivation of c-Myc, which results in tumor formation in chimeric mice, is a major roadblock in the translation of iPSCs into therapies. Although ectopic expression of c-Myc is not absolutely required for somatic reprogramming, in the absence of c-Myc, the overall efficiency of reprogramming is drastically reduced and the reprogramming time is increased. Subtle, abnormal epigenetic modifications in iPSCs derived in the absence of c-Myc have also been documented. Therefore, we developed a reprogramming method without c-Myc to generate high-quality iPSCs, a prerequisite to harnessing the full potential of iPSCs. In this study, we determined that serum replacement (SR)-based culture conditions dramatically increased the transcription factor-mediated reprogramming of mouse embryonic fibroblast cells (MEFs). The process was shortened to approximately 8 days when Oct4/Sox2/Klf4 (3F)-transduced MEFs were first cultured for 3 days under low serum conditions (LS protocol). The 3F-derived iPSCs that were generated by this method resembled mouse ES cells (mESCs) in morphology, gene expression, and in vitro differentiation. Finally, we observed that 3F-derived iPSC colonies were able to reach definite pluripotency in terms of molecular signatures when the catalytic function of c-Myc was tolerated. The 3F induction of pluripotency described here should facilitate the use of iPSCs and may also facilitate the mechanistic dissection of somatic reprogramming.

      • SCIESCOPUSKCI등재

        Synthesis of Thiazolo[4,5-d]pyrimidine Derivatives as Potential Antimicrobial Agents

        Habib, Nargues S.,Soliman, Raafat,El-Tombary, Alaa A.,El-Hawash, Soad A.,Shaaban, Omaima G. 대한약학회 2007 Archives of Pharmacal Research Vol.30 No.12

        In this study, we report the synthesis and antimicrobial evaluation of several new thiazolo[4,5-d]pyrimidine derivatives, namely 7-substituted amino-5-methyl-3-phenylthiazolo[4,5-d]pyrimidine-2(3H)-thiones 4a-e, 8, 13, 15, ethyl 2-cyano-2-(7-substituted-5-methyl-3-phenylthiazolo [4,5-d]-pyrimidin-2(3H)-ylidene)acetates 5a-b, 2-(7 -substituted-5-methyl-3-phenylthiazolo[4,5-d]pyrimidin-2(3H)-ylidene)malononitriles 6a-b, 5-methyl-7-morpholino-3-phenylthiazolo[4,5-d]pyrimidine-2(3H)-one 7, and 7-[4-(1-substituted-5-phenyl-4,5-dihydro-1H-pyrazolin-3-yl)anilino]-5-methyl-3-phenylthiazolo[4,5-d]pyrimidine-2(3H)-thiones 10-12. Some of the tested compounds were more active against C. albicans than E. coli and P. aeruginosa, and all were inactive against S. aureus.

      • SCIESCOPUSKCI등재

        Effect of Cattle Genotype and Variable Feed Supply on Forage Intake and Digestibility

        Habib, M.,Pollott, G.E.,Leaver, J.D. Asian Australasian Association of Animal Productio 2008 Animal Bioscience Vol.21 No.10

        An experiment was carried out to investigate whether a local breed of cattle is better adapted than European breed crosses to low quality feeds and to variations in their supply. Four Red Chittagong (RC) and four Holstein cross Sahiwal (Hx) cattle were used to compare the intake and digestibility of German grass (Echinocloa crusgalli) and rice straw with four regimes of feed supply. These were; a choice of German grass and rice straw each offered ad libitum on the same day (A); German grass and rice straw offered ad libitum on alternate days (B); rice straw offered ad libitum for 5 days followed by German grass ad libitum for 5 days (C); and German grass offered ad libitum for 5 days followed by rice straw ad libitum for 5 days (D). Each breed was offered the treatments in a $4{\times}4$ Latin Square design. The German grass intake and total dry matter intake per kg metabolic live weight were significantly higher for the Hx than for RC, but there were no significant effects of genotype on digestibility of nutrients or live weight. Treatment A had the highest proportion of German grass relative to rice straw in the total DM intake, and had the highest total DM intake and apparent digestibility of nutrients compared with treatments B, C and D. It was concluded that there was no significant evidence that the RG cattle were better adapted to a variable supply of low quality feed than Hx cattle, and that the variable feed supply reduced the ability of cattle to select a preferred diet and consequently nutrient intake was depressed.

      • KCI등재

        Synthesis of Thiazolo[4,5-d]pyrimidine Derivatives as Potential Antimicrobial Agents

        Nargues S. Habib,Raafat Soliman,Alaa A. El-Tombary,Soad A. El-Hawash,Omaima G. Shaaban 대한약학회 2007 Archives of Pharmacal Research Vol.30 No.12

        In this study, we report the synthesis and antimicrobial evaluation of several new thiazolo[4,5- d]pyrimidine derivatives, namely 7-substituted amino-5-methyl-3-phenylthiazolo[4,5-d]pyrimidine- 2(3H)-thiones 4a-e, 8, 13, 15, ethyl 2-cyano-2-(7-substituted-5-methyl-3-phenylthiazolo [4,5-d]-pyrimidin-2(3H)-ylidene)acetates 5a-b, 2-(7-substituted-5-methyl-3-phenylthiazolo[4,5- d]pyrimidin-2(3H)-ylidene)malononitriles 6a-b, 5-methyl-7-morpholino-3-phenylthiazolo[4,5-d] pyrimidine-2(3H)-one 7, and 7-[4-(1-substituted-5-phenyl-4,5-dihydro-1H-pyrazolin-3-yl)anilino]-5- methyl-3-phenylthiazolo[4,5-d]pyrimidine-2(3H)-thiones 10-12. Some of the tested compounds were more active against C. albicans than E. coli and P. aeruginosa, and all were inactive against S. aureus.

      • KCI등재

        GROUPS OF GALAXIES IN HISTORY: EVOLUTION IN THE MILLENNIUM SIMULATION

        HASHEMIZADEH, ABDOLHOSEIN,KHOSROSHAHI, HABIB G.,RAOUF, MOJTABA,NEZHAD, ALIREZA MOLAEI The Korean Astronomical Society 2015 天文學論叢 Vol.30 No.2

        We use the millennium simulation for studying the evolution of groups of galaxies over time. We find fossil and non-fossil groups as well as old and young groups at redshift z = 0 and follow them back in time to investigate the evolution of their parameters, such as mass assembly, luminosity gap and halo mass concentration. We find that fossils assemble a larger fraction of their mass at z = 0 than controls. The magnitude gaps between fossil and non-fossil groups are not the same because of major and minor mergers, in old and young groups as well. We also find that WMAP1 and WMAP7 cosmologies lead to the same evolutionary history for fossil and control groups.

      • SCIESCOPUSKCI등재

        Study of Factors Leading to Seasonality of Reproduction in Dairy Buffaloes. II. Non-Nutritional Factors

        Qureshi, M.S.,Habib, G.,Samad, H.A.,Lodhi, L.A.,Usmani, R.H. Asian Australasian Association of Animal Productio 1999 Animal Bioscience Vol.12 No.7

        Fifth one Nili-Ravi dairy buffaloes in their last two months of gestation, were selected in NWFP Pakistan. Rectal palpation was carried out fortnightly, until the occurrence of first estrus. Ovulation was confirmed per rectum and milk progesterone levels (MPL). Body condition score (BCS)was recorded weekly. Milk samples were collected weekly for MPL and blood samples fortnightly for metabolites analysis. Milk yield was recorded and samples were collected for milk fat. The buffaloes calving during the normal breeding season (NBS, August to January)had short (p<0.01) postpartum estrus interval of $55.95{\pm}4.90$ days versus $91.15{\pm}11.61 $ days in the buffaloes calving during the low breeding season (LBS, February to July). MPL in the LBS calvers remained lower than NBS calves (p<0.01). The incidence of silent ovulation was higher during LBS as compared to NBS (70.6% versus 29.4%). MPL showed a pattern opposite to atmospheric temperature. In NBS calvers serum glucose levels were higher (p<0.01) and magnesium levels were lower (p<0.01) than LBS calvers. Higher serum urea was found in summer and spring than that autumn and winter (p<0.05). The reproductive performance in buffaloes calving in the LBS coincided with a low BCS (p<0.01). Fat corrected milk production (FCM) was higher in NBS than LBS (p<0.01) calvers.

      • KCI등재

        AGE DATING GALAXY GROUPS IN THE MILLENNIUM SIMULATION

        RAOUF, MOJTABA,KHOSROSHAHI, HABIB G. The Korean Astronomical Society 2015 天文學論叢 Vol.30 No.2

        We study galaxies drawn from the semi-analytic models of Guo et al. (2011) based on the Millennium Simulation. We establish a set of four observationally measurable parameters which can be used in combination to identify a subset of galaxy groups which are old, with a very high probability. We therefore argue that a sample of fossil groups selected based on the luminosity gap will result in a contaminated sample of old galaxy groups. By adding constraints on the luminosity of the brightest galaxy, and its offset from the group luminosity centroid, we can considerably improve the age-dating.

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