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Kazuhiko Goto,Takenao Sugi,Yoshitaka Matsuda,Satoru Goto,Hiroki Fukuda,Yoshinobu Goto,Takao Yamasaki,Shozo Tobimatsu 제어로봇시스템학회 2013 제어로봇시스템학회 국제학술대회 논문집 Vol.2013 No.10
Visual evoked potentials (VEPs) are the electrical responses from the brain concerned with visual information processing. Amplitude of VEPs is smaller than that of background EEG activity, and the stimulus-locked averaging method is usually used for obtained the waveform. VEP response to each stimulus is not completely the same however it is varying with its amplitude and duration. Therefore, amplitude of averaged VEP waveform deteriorates due to their variability in raw data. Feature extraction of background EEG activity during visual stimulation is also a one of significant items in VEP analysis. In that case, separation of VEP component and background EEG component (mainly posterior dominant rhythm) is crucial. In the past, we proposed the method of estimating both amplitude of VEP and dominant rhythm by use of EEG model. This present study, the proposed method was applied to actual recorded VEP data and its effectiveness was evaluated. EEGs with visual stimulus were recorded from nine healthy young adults. Usefulness of the proposed method was investigated by comparing the conventional power spectrum averaging method. The proposed method will be applicable to show an accurate VEP analysis and characteristic analysis of background activity under visual stimulus.
The leading ideal of a complete intersection of height two, Part II
Goto, Shiro,Heinzer, William,Kim, Mee-Kyoung Elsevier 2007 Journal of algebra Vol.312 No.2
<P><B>Abstract</B></P><P>Let (S,n) be a regular local ring and let I=(f,g) be an ideal in <I>S</I> generated by a regular sequence f,g of length two. Let R=S/I and m=n/I. As in [S. Goto, W. Heinzer, M.-K. Kim, The leading ideal of a complete intersection of height two, J. Algebra 298 (2006) 238–247], we examine the leading form ideal <SUP>I∗</SUP> of <I>I</I> in the associated graded ring G=<SUB>grn</SUB>(S). If <SUB>grm</SUB>(R) is Cohen–Macaulay, we describe precisely the Hilbert series H(<SUB>grm</SUB>(R),λ) in terms of the degrees of homogeneous generators of <SUP>I∗</SUP> and of their successive GCD's. If D=GCD(<SUP>f∗</SUP>,<SUP>g∗</SUP>) is a prime element of <SUB>grn</SUB>(S) that is regular on <SUB>grn</SUB>(S)/(<SUP>f∗</SUP>D,<SUP>g∗</SUP>D), we prove that <SUP>I∗</SUP> is 3-generated and a perfect ideal. If <SUB>ht<SUB>grn</SUB>(S)</SUB>(<SUP>f∗</SUP>,<SUP>g∗</SUP>,<SUP>h∗</SUP>)=2, where h∈I is such that <SUP>h∗</SUP> is of minimal degree in <SUP>I∗</SUP>∖(<SUP>f∗</SUP>,<SUP>g∗</SUP>)<SUB>grn</SUB>(S), we prove <SUP>I∗</SUP> is 3-generated and a perfect ideal of <SUB>grn</SUB>(S), so <SUB>grm</SUB>(R)=<SUB>grn</SUB>(S)/<SUP>I∗</SUP> is a Cohen–Macaulay ring. We give several examples to illustrate our theorems.</P>
No Association between the CDX2 G543C Polymorphism and Risk of Gastric Atrophy and Cancer
Goto, Yasuyuki,Kato, Tsuyoshi,Ando, Takafumi,Goto, Hidemi,Hamajima, Nobuyuki Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.11
Ectopic expression of CDX2 in the stomach is closely associated with chronic Helicobacter pylori (H. pylori) infection and intestinal metaplasia. Whether CDX2 has tumor suppression or tumorigenesis potential remains to be elucidated. In this study, we investigated the association between the CDX2 G543C polymorphism (silent mutation) and the risk for H. pylori-induced gastric atrophy and cancer as well as H. pylori infection, using 454 Japanese subjects undergoing a health checkup and 202 gastric cancer patients. The frequency of the minor allele was the same as previously reported in China, but different from that reported in England. CDX2 G543C was not associated with risk of H. pylori infection, gastric atrophy, or gastric cancer, although the point estimate for non-cardiac differentiated gastric cancer as compared to controls with gastric atrophy was 2.22 (95%CI=0.17-29.4). In conclusion, our results indicate that the CDX2 G543C polymorphism is unlikely to affect the H. pylori infection-gastric atrophy-gastric cancer sequence.
Quantitative analysis between visual mismatch negativity and psychopathology scale for schizophrenia
Kazuhiko Goto,Takenao Sugi,Toshihiko Maekawa,Katuya Ogata,Yoshinobu Goto,Shozo Tobimatsu,Masatoshi Nakamura 제어로봇시스템학회 2009 제어로봇시스템학회 국제학술대회 논문집 Vol.2009 No.8
Visual mismatch negativity (v-MMN) in electroencephalographic (EEG) record provides an index of preattentive information processing of the brain v-MMN is considered to reflect schizophrenia. The positive and negative syndrome scale (PANSS) is usually used in clinical diagnosis on patients with schizophyenia for estimating the degree of disorder. In this study, the relationship between v-MMN and PANSS was analyzed. Characteristic parameters of peals including N1, N2, P300, and MMN were established respectively. Estimated function was constructed by selected parameters. P300 was most significant characteristic related to all items of FANSS.
Tensile Properties and Fatigue Strength of Ultrafine Grained Pure Copper
Goto, Masahiro,Han, Seung Zeon,Kim, Sang Shik,Kawagoishi, Norio,Lim, Cha Yong Trans Tech Publications, Ltd. 2007 Key Engineering Materials Vol.353-358 No.3
<P>Oxygen-free copper was processed by equal channel angular pressing with different numbers of ECAP process cycles, NP. Tensile strength was increased with an increase in NP, but it tended to saturate after NP = 4. Conversely, elongation was dramatically decreased by first pressing, but it tended to saturate up to NP = 3, followed by slight increasing trend after NP = 4. Fatigue tests of specimens processed with NP = 4 and 8 were performed. The change in surface morphologies during fatigue was monitored successively. In addition to this, the change in surface hardness was measured. Significant decrease in surface hardness due to cyclic stresses was measured. The physical basis of fatigue damage of UFG copper was discussed based on the experimental results.</P>
Advancements in the Diagnosis of Gastric Subepithelial Tumors
Goto Osamu,Kaise Mitsuru,Iwakiri Katsuhiko 거트앤리버 소화기연관학회협의회 2022 Gut and Liver Vol.16 No.3
A diagnosis of subepithelial tumors (SETs) is sometimes difficult due to the existence of overlying mucosa on the lesions, which hampers optical diagnosis by conventional endoscopy and tissue sampling with standard biopsy forceps. Imaging modalities, by using computed tomography and endoscopic ultrasonography (EUS) are mandatory to noninvasively collect the target’s information and to opt candidates for further evaluation. Particularly, EUS is an indispensable diagnostic modality for assessing the lesions precisely and evaluating the possibility of malignancy. The diagnostic ability of EUS appears increased by the combined use of contrast-enhancement or elastography. Histology is the gold standard for obtaining the final diagnosis. Tissue sampling requires special techniques to break the mucosal barrier. Although EUS-guided fine-needle aspiration (EUS-FNA) is commonly applied, mucosal cutting biopsy and mucosal incision-assisted biopsy are comparable methods to definitively obtain tissues from the exposed surface of lesions and seem more useful than EUS-FNA for small SETs. Recent advancements in artificial intelligence (AI) have a potential to drastically change the diagnostic strategy for SETs. Development and establishment of noninvasive methods including AI-assisted diagnosis are expected to provide an alternative to invasive, histological diagnosis.