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Compositional Correlations in Canine Genome Reflects Similarity with Human Genes
Joy, Faustin,Basak, Surajit,Gupta, Sanjib Kumar,Das, Pranab Jyoti,Ghosh, Shankar Kumar,Ghosh, Tapash Chandra Korean Society for Biochemistry and Molecular Biol 2006 Journal of biochemistry and molecular biology Vol.39 No.3
The base compositional correlations that hold among various coding and noncoding regions of the canine genome have been analysed. The distribution pattern of genes, on the basis of $GC_3$ composition, shows a wide range similar to that observed in human. However the occurrence of maximum number of genes was observed in the range of 65-75% of $GC_3$ composition. The correlation between the coding DNA sequences of canine with the different noncoding regions (introns and flanking regions) is found to be significant and in many cases the degree of correlation show similarity to human genome. We found that these correlations are not limited to the GC content alone, but is holding at the level of the frequency of individual bases as well. The present study suggests that canines ideally belong to the predicted 'general mammalian pattern' of genome composition along with human beings.
Mahuya Pakhira,Subhajit Ghosh,Surajit Ghosh,Dhruba P. Chatterjee,Arun K. Nandi 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.112 No.-
Biocidal and anti-fouling properties in the same polymeric membranes are important in biomedical fieldfor their capability to protect serious infection and filtration of biological molecules. For this purpose wereport random graft copolymer of poly(vinylidene fluoride) (PVDF-graft-poly(tBAEMA-ran-OEGMA,PVBO) membranes showing both antifouling and antibacterial activity. The PVBO copolymer is synthesisedusing ATRP technique and the polymer membranes are produced by breath figure (PVBO-1) andphase inversion (PVBO-2) techniques. The former shows well-developed hexagonal pores (diameter15 ± 3.5 nm), and good hydrophilicity (contact angle 41.3). PVBO-1 membrane exhibits good antifoulingproperty for both lysozyme and BSA solutions. Antimicrobial activity measured from agar diffusionmethod indicates that PVBO-1 shows a large zone of inhibition in case of gram-negative E coli andgram-positive S. aureus bacteria, whereas PVBO-2 and its HCl treated state (PVBO-3) membranes exhibitonly a moderate zone of inhibition. The MBC and MIC values indicate that the synthesized membranesare bactericidal in nature and not bacteriostatic. Live and dead cell assay indicates that PVBO-1 can significantlyinhibit growth of bacteria even at high bacteria concentration confirming high antimicrobialactivity. MTT assay suggests PVBO-1 is non-cytotoxic to mammalian cells and co-culturing activity resultsuggests high cellular selectivity of PVBO-1.
Did the countrywide lockdown act like a catalyst in turning a cyclone to a super‑cyclone AMPHAN?
Amit Kumar Chowdhury,Suvendu Manna,Paulami Ghosh,Surajit Mondal 대한공간정보학회 2022 Spatial Information Research Vol.30 No.6
Amid the COVID-19 pandemic and countrywide lockdown, the super-cyclone Amphan collided with the eastern coast of India, majorly affecting the Indian state of West Bengal. The lockdown restricted the industrial emissions of greenhouse gases known for increasing the average global temperature, however the sea-surface temperature (SST) profile over the Bay of Bengal indicated higher than average SST values in preceding 5 years. The unexpected increase in sea-surface temperature might have played a major role in formation cyclonic disturbances over the Bay of Bengal, which might have triggered the formation of super cyclone Amphan. The anomalous increase in average SST could be attributed to the sudden lowering of particulate matter concentration due to the lockdown, which resulted in the increase in levels of solar insolation on the sea-surface due to the absence of particulate matter load, which reflects/ absorbs the incoming solar radiation to the surface keeping the sea-surface temperature at lower levels.
Kumar Arvind,Kumar Manish,Chandra Sati Prakash,Srivastava Manish Kumar,Ghosh Surajit,Kumar Shiv 한국물리학회 2021 Current Applied Physics Vol.32 No.-
Control on the size of copper oxide (CuO) in the nano range is a highly motivating approach to study its multifunctional nature. The present investigation reports a sol-gel derived Ni doped CuO nanoparticles (Cu1- xNixO). Rietveld refinement of the XRD spectra confirms the formation of single monoclinic phase of Cu1-xNixO nanoparticles having crystallite size within the range of 19–21 nm. Raman spectra show the presence of characteristics Raman active modes and vibrational bands in the Cu1-xNixO samples that corroborate the monoclinic phase of the samples as revealed by refinement of XRD data. The estimated band gap of pure CuO is found to be ~1.43 eV, which decreases with the increase of dopant concentration into CuO matrix. This result is in line with estimated crystallite size. Magnetization curves confirm the weak ferromagnetic nature of Cu1-xNixO nanoparticles which reveal the DMS phase. This weak magnetic nature may be induced in the samples due to the exchange interaction between the localized magnetic d-spins of Ni ions and carriers (holes or electrons) from the valence band of pristine CuO lattice. Replacement of Cu+2 by Ni+2 ions into the host CuO lattice induces the magnetization. The quantified value of squareness ratio (S < 0.5) confirms the inter-grain magnetic interactions in the Cu1-xNixO nanoparticles which is also the reason of weak induced magnetization.
Aggravation of CoVID-19 infections due to air pollutant concentrations in Indian cities
Asha Sunilkumar,Shishir Kumar Singh,Amit Kumar Mondal,Paulami Ghosh,Surajit Mondal 대한공간정보학회 2023 Spatial Information Research Vol.31 No.5
The CoVID-19 infections began rising worldwide during the initial weeks of March 2020, reacting to which the Government of India called for nationwide lockdown for ~ 3 weeks. The concentration of pollutants during the lockdown were compared with pollution levels recorded during the preceding year for the same time frame. A direct relationship was established between the high level of air pollutants (PM2.5, PM10, NO2 and SO2) and CoVID-19 infections being reported in the Indian cities. The correlation indicates that the air pollutants like PM2.5, PM10, NO2 and SO2 are aggravating the number of casualties due to the CoVID-19 infections. The transmission of the virus in the air is in the form of aerosols; and hence places which are highly polluted may see a proportionate rise in CoVID-19 cases The high-level exposure of PM2.5 over a long period is found to be significantly correlated with the mortality per unit confirmed CoVID-19 cases as compared to other air pollutant parameters like PM10, NO2 and SO2.