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Lee, Yong-Jin,Lee, Tong-Geon,Jeon, Woong-Bae,Kim, Dae-Yeon,Hong, Min-Jeong,Lee, Man-Bo,Hyun, Jong-Nae,Kim, Mi-Jung,Lee, Mi-Ja,Park, Cheol-Su,Seo, Yong-Weon 한국작물학회 2010 Journal of crop science and biotechnology Vol.13 No.2
Cereal seed storage proteins are encoded by complex multigene families and their subunit profiles are highly related to end-use qualities. Each fraction of albumin and hordein was extracted and its subunit profile was evaluated in related to malt and grain quality parameters. The purpose of this study was to provide selection criteria for high quality malting barley using grain and malt quality parameters and biochemical-genetic information. Grain and malt quality of 13 local adaptability test (LAT) lines were evaluated for malting process. A total of 16 germplasm accessions of high or low seed storage protein content were also evaluated for biochemical-genetic analysis. The correlation coefficients among quality parameters were analyzed. Several important quality parameters in brewing process showed significant positive or negative correlations. Seed storage protein subunits of albumin and hordein of all tested lines and accessions were evaluated using 12% 1D SDS-PAGE. Scored data of protein subunit's presence or absence was applied to Agglomerative Hierarchical Clustering (AHC) for statistical analysis and showed specific grouping patterns among tested lines. Clustered lines with subunit information were highly related with agricultural performance and grain and malt qualities. Based on the profiles of seed storage protein subunits, association of hordein subunit of 38, 43, and 65 kDa with high malt scored lines was found. The obtained results would provide improved selection criteria for high quality malting barley in the malting barley breeding program.
Lee, Geon-Woong,Bang, Dae-Suk,Cho, Dong-Hwan,Kumar, Satish Korean Carbon Society 2007 Carbon Letters Vol.8 No.4
A method for evaluating bulk sensitive structural characteristics of unpurified, as-purified, and acid treated single walled carbon nanotubes (SWNTs) was described in the present study. The optical spectra of SWNT solutions were well resolved after prolonged sonication and they were correlated to the diameter and the distribution of nanotubes. The acid-treated SWNTs were similar to as-purified SWNTs in terms of catalyst residue, radial breathing mode (RBM) in the Raman spectra, and the first band gap energy of semiconducting tubes in the optical spectra. The solution phase optical spectra were more sensitive to changes in the small diameter and metallic tubes after the acid treatment than were the RBM spectra.
Feasibility of α-fetoprotein as a diagnostic tool for hepatocellular carcinoma in Korea
( Dae Geon Ahn ),( Hyung Joon Kim ),( Hyun Kang ),( Hyun Woong Lee ),( Si Hyun Bae ),( Joon Hyoek Lee ),( Yong Han Paik ),( June Sung Lee ) 대한내과학회 2016 The Korean Journal of Internal Medicine Vol.31 No.1
Background/Aims: The aim of this study was to evaluate the feasibility of α-fetoprotein (AFP) as a diagnostic tool for hepatocellular carcinoma (HCC) in Korean patients. Methods: We retrospectively reviewed the medical records of HCC and cirrhosis patients at three hospitals. For each HCC patient, a cirrhosis patient matched for age, sex, etiology, and Child-Pugh classification was selected by simple random sampling. The performance of AFP in the diagnosis of HCC was determined using receiver operating characteristic curve analysis. Results: A total of 732 patients with HCC or cirrhosis were selected for each case and the control groups. The mean age was 54 years, and 72.4% of patients were male. The mean serum AFP levels in the HCC group and cirrhosis group were 3,315.6 and 117.2 ng/mL, respectively (p < 0.001). The area under the receiver operating characteristic curve for all HCC patients was 0.757. The sensitivity, specificity, and positive predictive value of AFP was 50.55%, 87.70%, and 80.43%, respectively, at a cut-off of 20 ng/mL; 37.70%, 95.90%, and 90.20%, respectively, at a cut-off of 100 ng/mL, and 30.05%, 97.27%, and 91.67%, respectively, at a cut-off of 200 ng/mL. A cut-off of 100 ng/mL was more sensitive than one of 200 ng/mL with equivalent specificity and positive predictive value. Conclusions: The cut-off AFP value for early-stage HCC was 17.4 ng/mL. Our study cautiously suggests that AFP has a role in the diagnosis of HCC, and that the appropriate value of AFP for the diagnosis of HCC may be 100 ng/mL rather than 200 ng/mL.
이건식(Geon-Sik Lee),모동영(Dong-Yeong Mo),이상철(Sang-Cheol Lee),최창영(Chang-Young Choi),조춘호(Chun-Ho Cho),김태웅(Tae-Woong Kim),박귀근(Gwi-Geun Park) 전력전자학회 2010 전력전자학술대회 논문집 Vol.2010 No.7
매트릭스컨버터의 제어기법은 입력측의 전류형과 출력측의 전압형의 조합에 의해 구성된 미래지향형 AC/AC 전력변환시스템이다. 이를 제어하기위해서 기존 SVPWM을 적용하면 섹터정보 및 인가시간의 계산과정이 복잡해지고 계산량이 많아지는 단점이 있다. 본 논문에서는 상기의 문제점을 해결하기 위해 전압형 인버터에 사용하고 있는 기존 간략형 SVPWM과 함께 입력측 전류형에도 이를 변형하여 적합한 간략형 SVPWM를 동시에 적용하여 전체의 PWM에 관련된 계산과정을 단순화시키고 계산량을 저감시킬 수 있는 제어기법을 제안한다.
( Yeong Geon Lee ),( Jae Woong Hwang ),( Sang Bum Park ),( Il Seob Shin ),( Soo Kyung Kang ),( Kwang Won Seo ),( Yong Soon Lee ),( Kyung Sun Kang ) 한국조직공학·재생의학회 2008 조직공학과 재생의학 Vol.5 No.4
Therapy using stem cells for the liver fibrosis is a prospective alternative to overcome the insufficiency of transplantable liver donor. Here, we demonstrated xenogeneic human cell therapy for the treatment of rat liver fibrosis without the use of an immunosuppressant. Liver fibrosis was induced by dimethylnitrosamine for 5 weeks in six-week-old male Sprague-Dawley rats. Human umbilical cord blood- and adipose tissue-derived multipotent stem cells were injected intravenously by the tail vein after one week. Blood samples were collected and liver samples were stained with Masson`s trichrome in order to evaluate the amount of fibrosis. After the cell injection, the level of total protein, albumin, alanine transaminase and aspartic acid transaminase was recovered to the similar level of the normal rats. The liver weight per body weight increased after the cell injection. Collagen fiber, near the portal triad and marginal region, was reduced, significantly. Taken together, it is suggested that xenotransplantation of multipotent stem cells might be a candidate for the treatment of liver fibrosis without the use of an immunosuppresant.