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( Ga-eun Kim ),( Su-jee Park ),( Yeong Jin Kim ),( Seul-kee Kim ),( Tae-young Jung ) 대한뇌종양학회·대한신경종양학회·대한소아뇌종양학회 2023 Brain Tumor Research and Treatment Vol.11 No.3
Arachnoid cysts are usually asymptomatic and discovered incidentally. However, cysts may occasionally rupture because of minor head trauma. We describe the radiologic follow-up of 5 patients with ruptured arachnoid cysts featuring spontaneous resolution, subdural hygroma formation, and cystic and subdural hemorrhage. From January 2004 through July 2020, 5 patients (1.3%) with ruptured arachnoid cysts were evaluated out of 388 patients with arachnoid cysts encountered at our institution at that time. The 5 patients were all male, and they ranged in age from 6-17 years (median, 12 years). The median duration of radiologic follow-up was 3.5 years (range, 2.3-10.1 years). All of the ruptured arachnoid cysts were overlying the temporal lobe with Galassi type II. The median cyst diameter was 4.9 cm (range, 4.4-8.9 cm). Four patients had a history of recent minor head trauma. There were no particular neurologic symptoms in their past medical history in all patients. In the follow-up, two patients’ cysts resolved spontaneously without hemorrhage. One patient’s cyst resolved post-burr-hole drainage for chronic subdural hemorrhage. Another patient, whose cyst led to a hemorrhage and chronic subdural hemorrhage, recovered following a craniotomy, hematoma removal, and cyst fenestration. Another patient, presenting with hygroma, cystic hemorrhage, and chronic subdural hemorrhage, was treated with burr-hole drainage. Three patients recovered postoperatively. Arachnoid cysts rarely rupture, and surgical intervention is required for some cases associated with hemorrhage. Postoperatively, all patients had good outcomes without complications in this series.
Existence of glioma stroma mesenchymal stemlike cells in Korean glioma specimens.
Kim, Young Goo,Jeon, Soyoun,Sin, Ga-Yeong,Shim, Jin-Kyoung,Kim, Bo-Kyung,Shin, Hye-Jin,Lee, Ji-Hyun,Huh, Yong-Min,Lee, Su-Jae,Kim, Eui-Hyun,Park, Eun Kyung,Kim, Se-Hoon,Chang, Jong Hee,Kim, Dong Seok Springer Verlag 2013 Child’s nervous system Vol.29 No.4
<P>It was presented that mesenchymal stem cells (MSCs) can be isolated from western glioma specimens. However, whether MSCs exist in glioma specimens of different ethnicities is unknown. To verify the existence of MSCs in an independent cohort, we undertook studies to isolate MSCs from a group of Korean patients. We hypothesized that cells resembling MSCs that were deemed mesenchymal stemlike cells (MSLCs) exist in an independent cohort of Korean gliomas. We cultured fresh glioma specimens using the protocols used for culturing MSCs. The cultured cells were analyzed with fluorescence-activated cell sorting (FACS) for surface markers associated with MSCs. Cultured cells were exposed to mesenchymal differentiation conditions. To presume possible locations of MSLCs in the glioma, sections of glioma were analyzed by immunofluorescent labeling for CD105, CD31, and NG2. From nine of 31 glioma specimens, we isolated cells resembling MSCs, which were deemed Korean glioma stroma MSLCs (KGS-MSLCs). KGS-MSLCs were spindle shaped and adherent to plastic. KGS-MSLCs had similar surface markers to MSCs (CD105(+), CD90(+), CD73(+), and CD45(-)). KGS-MSLCs were capable of mesenchymal differentiation and might be located around endothelial cells, pericytes, and in a disorganized perivascular area inside glioma stroma. We found that cells resembling MSCs indeed exist in an independent cohort of glioma patients, as presented in western populations. We could presume that the possible location of KGS-MSLCs was in perivascular area or in glioma stroma that was a disorganized vascular niche. It might be possible that KGS-MSLCs could be one of constituent of stroma of glioma microenvironment.</P>
Kim, Ga Ram,Hur, Jin,Lee, Hye-Jeong,Nam, Ji Eun,Kim, Young Jin,Hong, Yoo Jin,Shim, Hyo Sup,Kim, Hee Yeong,Lee, Ji Won,Choi, Byoung Wook The American Cancer Society by Liss-Wiley, a subsi 2013 Cancer cytopathology Vol.121 No.4
<P>The purpose of this study was to assess whether analyses of tumor markers in cytological fluid can improve the performance of computed tomography (CT)-guided needle aspiration biopsy (NAB) for the diagnosis of ground-glass opacity (GGO) pulmonary lesions.</P>
Kim, Ga-Yeong,Heo, Jina,Kim, Hee-Sik,Han, Jong-In Elsevier 2017 Bioresource technology Vol.237 No.-
<P><B>Abstract</B></P> <P>In this study, bicarbonate was proposed as an alternative carbon source to overcome exceedingly low CO<SUB>2</SUB> fixation efficiency of conventional microalgae cultivation system. 5gL<SUP>−1</SUP> of sodium bicarbonate was found to well support the growth of <I>Dunaliella salina</I>, showing 2.84-fold higher specific growth rate than a bicarbonate-free control. This bicarbonate-fed cultivation also could yield biomass productivity similar to that of CO<SUB>2</SUB>-based system as long as pH was controlled. While the supplied CO<SUB>2</SUB>, because of its being a gas, was mostly lost and only 3.59% of it was used for biomass synthesis, bicarbonate was effectively incorporated into the biomass with 91.40% of carbon utilization efficiency. This study showed that the bicarbonate-based microalgae cultivation is indeed possible, and can even become a truly environment-friendly and workable approach, provided that a CO<SUB>2</SUB> mineralization technology is concomitantly established.</P> <P><B>Highlights</B></P> <P> <UL> <LI> To utilize bicarbonate as carbon source for microalgae cultivation was investigated. </LI> <LI> The specific growth rate of <I>Dunaliella</I> sp. was significantly increased with NaHCO<SUB>3</SUB>. </LI> <LI> pH control was important to obtain high biomass productivity with bicarbonate. </LI> <LI> NaHCO<SUB>3</SUB> positively affected not only for growth but also for carotenoid production. </LI> <LI> With bicarbonate, carbon utilization efficiency was apparently higher than with CO<SUB>2</SUB>. </LI> </UL> </P>