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      • KCI우수등재

        SOLVING FUZZY FRACTIONAL WAVE EQUATION BY THE VARIATIONAL ITERATION METHOD IN FLUID MECHANICS

        FIRDOUS KHAN,KIRTIWANT P. GHADLE 한국산업응용수학회 2019 Journal of the Korean Society for Industrial and A Vol.23 No.4

        In this paper, we are extending fractional partial differential equations to fuzzy fractional partial differential equation under Riemann-Liouville and Caputo fractional derivatives, namely Variational iteration methods, and this method have applied to the fuzzy fractional wave equation with initial conditions as in fuzzy. It is explained by one and two-dimensional wave equations with suitable fuzzy initial conditions.

      • KCI등재후보
      • SCIESCOPUSKCI등재

        Changes in Chemical Composition of Sorghum as Influenced by Growth Stage and Cultivar

        Firdous, Rafia,Gilani, Abrar Hussain Asian Australasian Association of Animal Productio 2001 Animal Bioscience Vol.14 No.7

        To determine the effect of different growth stages and cultivars on the chemical composition of sorghum plant and its morphological fractions, samples of whole plant, leaf and stem of J.S-263, J.S-88 and Hegari cultivars, harvested at various growth stages were drawn for analysis. All the samples were analysed for their dry matter contents and various cell wall components such as NDF, ADF. hemicellulose, cellulose, lignin, cutin and silica. Significant increase in DM contents of whole sorghum plant, leaf and stem was observed with advancing stage of growth. The highest DM content was recorded in leaf fraction of the plant. All the cell wall constituents increased significantly in whole sorghum plant, leaf and stem as the plant matured. The maximum NDF, ADF, cellulose and lignin contents were observed in stem fraction, followed by whole plant. However, the hemicellulose, cutin and silica contents were higher in leaf fraction of the plant. The cultivars were found to have some effect on the chemical composition of whole plant, leaf and stem fractions. The results indicated that plant maturity had a much greater effect on the chemical composition of sorghum plant, whereas it was little affected by cultivars.

      • SCIESCOPUSKCI등재

        Effect of Stage of Growth and Cultivar on Chemical Composition of Whole Maize Plant and Its Morphological Fractions

        Firdous, R.,Gilani, A.H. Asian Australasian Association of Animal Productio 1999 Animal Bioscience Vol.12 No.3

        Samples of whole plant, leaf and stem of Akbar, Neelum, UM-81 and lZ-31 cultivars of maize fodder harvested up to 14 weeks at different growth stages were drawn and analysed for dry matter contents and various cell wall constituents such as NDF, ADF, hemicellulose, cellulose, lignin, cutin and silica. The dry matter contents of whole maize plant, leaf and stem increased significantly (p<0.01) with advancing plant age. Maximum dry matter was found in the leaf fraction of the plant. The cell wall components continued to increase significantly (p<0.001) in whole maize plant and its morphological fractions as the age advanced. Maximum values for NDF, ADF, cellulose and lignin were observed in stem followed by whole plant and leaf, whereas hemicellulose, cutin and silica contents were higher in leaf fraction of the plant. The cultivars were observed to have some effects on chemical composition of all plant fraction. The results indicated that maturity had a much greater effect on the concentration of all the structural components than did the cultivars. It was concluded that maize fodder should be cut preferably between 8th to 9th week of age (flowering stage) to obtain more nutritious and digestible feed for livestock. Among the maize cultivars, Neelum proved to be the best, due to its higher dry matter contents and lower lignin concentration.

      • Preliminary studies on the microplastic pollution in Dal lake, Kashmir (first report)

        Firdous, Juhi,Mathur, Yatindra Kumar,Jeelani, Mubashir,Aziz, Adnan,Azmat, Seema,Mudasir, Syeed Techno-Press 2020 Advances in environmental research Vol.9 No.4

        We provide the first study on the occurrence of microplastics in Dal lake, Kashmir, India. Microplastics act as catastrophe that trigger many environmental problems. The key origins of microplastics are larger plastics, which split into smaller plastics after UV light disintegration. There is relatively little work carried out on the existence of microplastics. The present work has been undertaken on the occurrence of microplastics at four pre-selected sites (surface water) in Dal lake, Kashmir. The samples were taken to the laboratory to dissolve organic matter by using H2O2 (6%). To speed up the organic digestion; the treated mixture was heated on a hot plate at 70℃. The mixture was then subjected to density separation. The supernatant obtained was observed under the microscope (10X) and measurements were taken. At site-I, the microplastics ranged from 2-3 mm, site-II 5-6 mm, site-III 3-4 mm, site-IV 4-5 mm in thickness, indicating the presence of microplastics in the lake. The presence of microplastics indicated that the lake has undergone an anthropogenic change over a period of time. Our research highlights the value of enhancing the quality of the drainage system and sewage disposal. This work can be helpful to recognize successful microplastic control management techniques and possible threats associated with the Dal lake. So far, no such data on the presence of microplastics in Kashmir lakes is available.

      • SCIESCOPUSKCI등재

        Effect of Stage of Maturity and Cultivars on the Digestibility of Whole Maize Plant and its Morphological Fractions

        Firdous, R.,Gilani, A.H. Asian Australasian Association of Animal Productio 1999 Animal Bioscience Vol.12 No.8

        A study was conducted on four maize cultivars to determine the dry matter and fibre digestibility as influenced by advancing plant age. Samples of maize cultivars Akbar, Neelum, UM-81 and IZ-31 were harvested at weekly intervals/ growth stages. The samples of morphological fractions such as leaf and stem were also collected at various growth stages. Whole mixed fodder and different fractions of maize plant were analysed for their chemical composition and in vitro digestibility. The results showed that in vitro dry matter digestibility (IVDMD) of whole maize plant, leaf and stem decreased significantly with advancing stage of maturity. Digestibility of NDF, ADF, hemicellulose and cellulose decreased significantly in all plant parts with advancing plant age/growth stages. Maximum values for the digestibility of dry matter and various cell wall constituents were observed in leaf, followed by whole plant and stem fractions. Cultivars were observed to have significant effect of IVDMD and digestibility of NDF, ADF and cellulose in all plant fractions. The results indicated that digestibility of maize fodder was affected by stage of maturity and cultivars. However, maturity had a greater effect on digestibility in all plant fractions than did cultivars. Dry matter contents were found to be significantly and negatively correlated with IVDMD of whole plant and its leaf and stem fractions. Based on correlations, regression equations were computed to predict IVDMD.

      • KCI우수등재

        SYSTEMATIC APPROXIMATION OF THREE DIMENSIONAL FRACTIONAL PARTIAL DIFFERENTIAL EQUATIONS IN FLUID MECHANICS

        FIRDOUS KHAN,KIRTIWANT P. GHADLE 한국산업응용수학회 2019 Journal of the Korean Society for Industrial and A Vol.23 No.3

        In this article, a systematic solution based on the sequence of expansion method is planned to solve the time-fractional diffusion equation, time-fractional telegraphic equation and time-fractional wave equation in three dimensions using a current and valid approximate method, namely the ADM, VIM, and the NIM subject to the estimate initial condition. By using these three methods it is likely to find the exact solutions or a nearby approximate solution of fractional partial differential equations. The exactness, efficiency, and convergence of the method are demonstrated through the three numerical examples.

      • KCI등재

        Ophiamides A-B, New Potent Urease Inhibitory Sphingolipids from Heliotropium ophioglossum

        Sadiqa Firdous,Abdul Malik,Nida Hassan Ansari,Itrat Fatima,Nighat Afza,Lubna Iqbal,Mehreen Lateef 대한약학회 2012 Archives of Pharmacal Research Vol.35 No.7

        Ophiamides A (1) and B (2), two new sphingolipids have been isolated from the n-hexane subfraction of the MeOH extract of the whole plant of Heliotropium ophioglossum along with glycerol monopalmitate (3) and β-sitosterol 3-O-β-D-glucoside (4) reported for the first time from this species. Their structures were elucidated by spectroscopic techniques including MS and 2D-NMR spectroscopy. Both the compounds 1 and 2 showed potent inhibitory activity against the enzyme urease.

      • Design and application of chitosan microspheres as oral and nasal vaccine carriers: an updated review

        Islam, Mohammad Ariful,Firdous, Jannatul,Choi, Yun-Jaie,Yun, Cheol-Heui,Cho, Chong-Su Dove Medical Press 2012 INTERNATIONAL JOURNAL OF NANOMEDICINE Vol.7 No.-

        <P>Chitosan, a natural biodegradable polymer, is of great interest in biomedical research due to its excellent properties including bioavailability, nontoxicity, high charge density, and mucoadhesivity, which creates immense potential for various pharmaceutical applications. It has gelling properties when it interacts with counterions such as sulfates or polyphosphates and when it crosslinks with glutaraldehyde. This characteristic facilitates its usefulness in the coating or entrapment of biochemicals, drugs, antigenic molecules as a vaccine candidate, and microorganisms. Therefore, chitosan together with the advance of nanotechnology can be effectively applied as a carrier system for vaccine delivery. In fact, chitosan microspheres have been studied as a promising carrier system for mucosal vaccination, especially via the oral and nasal route to induce enhanced immune responses. Moreover, the thiolated form of chitosan is of considerable interest due to its improved mucoadhesivity, permeability, stability, and controlled/extended release profile. This review describes the various methods used to design and synthesize chitosan microspheres and recent updates on their potential applications for oral and nasal delivery of vaccines. The potential use of thiolated chitosan microspheres as next-generation mucosal vaccine carriers is also discussed.</P>

      • 5'-CpG Island Promoter Hypermethylation of the CAV-1 Gene in Breast Cancer Patients of Kashmir

        Syeed, Nidda,Hussain, Firdous,Husain, Syed Akhtar,Siddiqi, Mushtaq A. Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.1

        Background: Caveolin-1 (CAV-1), encoding the structural component of cellular caveolae, is a suggested tumor suppressor gene involved in cell signalling. Aberrant promoter methylation of CAV-1 is associated with inactivation of expression. We previously observed CAV-1 mutations in breast cancers and therefore devised this study to examine the hypermethylation status of the promoter region of CAV-1 with reference to breast cancer progression and development. Methods: Hypermethylation status of CAV-1 was analyzed by methylation specific PCR. Loss of expression of the CAV-1 gene was further evaluated by semi-quantitative rt-PCR. Results: 28/130 (21.5%) breast cancer cases showed promoter hypermethylation with reduced CAV-1 expression levels when compared with adjacent normal breast tissue. CAV-1 gene hypermethylation was significantly related to menopausal status, histopathological grade and age. Conclusion: The rationale of our study is that CAV-1 gene is transcriptionally repressed in breast cancer cells due to hypermethylation. Our results reveal that promoter hypermethylation and loss of expression of the CAV-1 gene is an important alternative mechanism for inactivation of CAV-1 leading to complete gene silencing.

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