New prediction equations for the estimation of maxillary mandibular canine and premolar widths from mandibular incisors and mandibular first permanent molar widths

Fazal Shahid,Mohammad Khursheed Alam,Mohd Fadhli Khamis 대한치과교정학회 2016 대한치과교정학회지 Vol.46 No.3

Objective: The primary aim of the study was to generate new prediction equations for the estimation of maxillary and mandibular canine and premolar widths based on mandibular incisors and first permanent molar widths. Methods: A total of 2,340 calculations (768 based on the sum of mandibular incisor and first permanent molar widths, and 1,572 based on the maxillary and mandibular canine and premolar widths) were performed, and a digital stereomicroscope was used to derive the the digital models and measurements. Mesiodistal widths of maxillary and mandibular teeth were measured via scanned digital models. Results: There was a strong positive correlation between the estimation of maxillary (r = 0.85994, r² = 0.7395) and mandibular (r = 0.8708, r² = 0.7582) canine and premolar widths. The intraclass correlation coefficients were statistically significant, and the coefficients were in the strong correlation range, with an average of 0.9. Linear regression analysis was used to establish prediction equations. Prediction equations were developed to estimate maxillary arches based on Y = 15.746 + 0.602 × sum of mandibular incisors and mandibular first permanent molar widths (sum of mandibular incisors [SMI] + molars), Y = 18.224 + 0.540 × (SMI + molars), and Y = 16.186 + 0.586 × (SMI + molars) for both genders, and to estimate mandibular arches the parameters used were Y = 16.391 + 0.564 × (SMI + molars), Y = 14.444 + 0.609 × (SMI + molars), and Y = 19.915 + 0.481 × (SMI + molars). Conclusions: These formulas will be helpful for orthodontic diagnosis and clinical treatment planning during the mixed dentition stage.

Comparative evaluation of gastroulcerogenic potential of nitrogen isoforms of salicyl alcohol and aspirin in rats: biochemical and histological study

Gowhar Ali,Fazal Subhan,Nazar Ul Islam,Nasir Ullah,Muhammad Shahid,Sami Ullah,Ihsan Ullah,Rehmat Shah,Ikhtiar Khan,Robert D. E. Sewell,Ghulam Abbas 대한약학회 2014 Archives of Pharmacal Research Vol.37 No.7

The aim of the current study was to explorein vivo any relative gastroulcerogenic prospective propensityof newly synthesized nitrogen containing derivativesof salicyl alcohol; compound (I) [1-(2-hydroxybenzyl)piperidinium chloride], compound (II) [4-carbamoyl-1-(2-hydroxybenzyl)piperidinium chloride] and aspirin in albinorats. The experimental groups received the following oraltreatments daily for 6 days: group I saline control; group II,standard (aspirin) treatment group [150 mg/kg of bodyweight]; group III, test (compound I) treatment group [100,150 mg/kg]; group IV, test (compound II) treatment group[100, 150 mg/kg]. The results showed that in the case of theaspirin treated group and compound (I) [150 mg/kg], therewas a significant increase in gastric volume, free acidity,total acidity, ulcer score and a decrease in gastric pH. Furthermore, histopathological examination of gastricmucosa of these treated groups revealed detectable morphologicalchanges. Utilizing the same protocol, syntheticcompound (I) [100 mg/kg] and (II) [100, 150 mg/kg]exhibited no statistically significant ulcerogenic or cytotoxicproperties. A cyclooxygenase (COX) selectivity test indicatedthe preferential inhibition of COX-I and COX-IIenzymes by compounds (I) and (II). This study thereforeindicates that these synthetic compounds may possessreduced ulcerogenic potential and could be a functionalsubstitute to aspirin.

Modeling and Analysis of Magnetized Nanomaterial Williamson Towards a Variable Thicked Surface Subject to Joule Heating and Activation Energy

Wei-Miao Qian,Fazal Haq,M. Ijaz Khan,Sohail A. Khan,Shahid Farooq 한국자기학회 2021 Journal of Magnetics Vol.26 No.2

Comparative evaluation of gastroulcerogenic potential of nitrogen isoforms of salicyl alcohol and aspirin in rats: biochemical and histological study

Ali, Gowhar,Subhan, Fazal,Islam, Nazar Ul,Ullah, Nasir,Shahid, Muhammad,Ullah, Sami,Ullah, Ihsan,Shah, Rehmat,Khan, Ikhtiar,Sewell, Robert D. E.,Abbas, Ghulam 대한약학회 2014 Archives of Pharmacal Research Vol.37 No.7

The aim of the current study was to explore in vivo any relative gastroulcerogenic prospective propensity of newly synthesized nitrogen containing derivatives of salicyl alcohol; compound (I) [1-(2-hydroxybenzyl) piperidinium chloride], compound (II) [4-carbamoyl-1-(2- hydroxybenzyl)piperidinium chloride] and aspirin in albino rats. The experimental groups received the following oral treatments daily for 6 days: group I saline control; group II, standard (aspirin) treatment group [150 mg/kg of body weight]; group III, test (compound I) treatment group [100, 150 mg/kg]; group IV, test (compound II) treatment group [100, 150 mg/kg]. The results showed that in the case of the aspirin treated group and compound (I) [150 mg/kg], there was a significant increase in gastric volume, free acidity, total acidity, ulcer score and a decrease in gastric pH. Furthermore, histopathological examination of gastric mucosa of these treated groups revealed detectable morphological changes. Utilizing the same protocol, synthetic compound (I) [100 mg/kg] and (II) [100, 150 mg/kg] exhibited no statistically significant ulcerogenic or cytotoxic properties. A cyclooxygenase (COX) selectivity test indicated the preferential inhibition of COX-I and COX-II enzymes by compounds (I) and (II). This study therefore indicates that these synthetic compounds may possess reduced ulcerogenic potential and could be a functional substitute to aspirin.

Influence of ultrasonic radiation on extraction and green dyeing of mordanted cotton using neem bark extract

Khalid Mahmood Zia,Shahid Adeel,Fazal-ur- Rehman,Habiba Aslam,Muhammad Kaleem Khosa,Mohammad Zuber 한국공업화학회 2019 Journal of Industrial and Engineering Chemistry Vol.77 No.-

The current research presents the exploration of coloring potential of neem bark under the influence ofultrasonic treatment. It is found that good color strength is obtained when tannin from bark is extractedin acidified methanol medium and is used to dye irradiated cotton fabric. New shades and good ratings offastness were obtained when optimal fabric was mordanted with herbal biomolecules where excellentrating has been obtained after bio-mordanting the fabrics under optimal conditions. It is concluded thatUS treatment being green tool in natural dyeing has a great potential to isolate colorants from plantsources under mild conditions.

Diversity in Betasatellites Associated with Cotton Leaf Curl Disease During Source-To-Sink Movement Through a Resistant Host

Iftikhar Ali Khan,Khalid Pervaiz Akhtar,Fazal Akbar,Ishtiaq Hassan,Imran Amin,Muhammad Saeed,Shahid Mansoor 한국식물병리학회 2016 Plant Pathology Journal Vol.32 No.1

Cotton leaf curl is devastating disease of cotton characterized by leaf curling, vein darkening and enations. The disease symptoms are induced by DNA satellite known as Cotton leaf curl Multan betasatellite (CLCuMuB), dominant betasatellite in cotton but another betasatellite known as Chili leaf curl betasatellite (ChLCB) is also found associated with the disease. Grafting experiment was performed to determine if host plant resistance is determinant of dominant population of betasatellite in cotton (several distinct strains of CLCuMuB are associated with the disease). Infected scion of Gossypium hirsutum collected from field (the source) was grafted on G. arboreum, a diploid cotton species, resistant to the disease. A healthy scion of G. hirsutum (sink) was grafted at the top of G. arboreum to determine the movement of virus/betasatellite to upper susceptible scion of G. hirsutum. Symptoms of disease appeared in the upper scion and presence of virus/betasatellite in the upper scion was confirmed via molecular techniques, showing that virus/betasatellite was able to move to upper scion through resistant G. arboreum. However, no symptoms appeared on G. arboreum. Betasatelites were cloned and sequenced from lower scion, upper scion and G. arboreum which show that the lower scion contained both CLCuMuB and ChLCB, however only ChLCB was found in G. arboreum. The upper scion contained CLCuMuB with a deletion of 78 nucleotides (nt) in the non-coding region between Arich sequence and βC1 gene and insertion of 27 nt in the middle of βC1 ORF. This study may help in investigating molecular basis of resistance in G. arboreum.

Diversity in Betasatellites Associated with Cotton Leaf Curl Disease During Source-To-Sink Movement Through a Resistant Host

Khan, Iftikhar Ali,Akhtar, Khalid Pervaiz,Akbar, Fazal,Hassan, Ishtiaq,Amin, Imran,Saeed, Muhammad,Mansoor, Shahid The Korean Society of Plant Pathology 2016 Plant Pathology Journal Vol.32 No.1

Cotton leaf curl is devastating disease of cotton characterized by leaf curling, vein darkening and enations. The disease symptoms are induced by DNA satellite known as Cotton leaf curl Multan betasatellite (CLCuMuB), dominant betasatellite in cotton but another betasatellite known as Chili leaf curl betasatellite (ChLCB) is also found associated with the disease. Grafting experiment was performed to determine if host plant resistance is determinant of dominant population of betasatellite in cotton (several distinct strains of CLCuMuB are associated with the disease). Infected scion of Gossypium hirsutum collected from field (the source) was grafted on G. arboreum, a diploid cotton species, resistant to the disease. A healthy scion of G. hirsutum (sink) was grafted at the top of G. arboreum to determine the movement of virus/betasatellite to upper susceptible scion of G. hirsutum. Symptoms of disease appeared in the upper scion and presence of virus/betasatellite in the upper scion was confirmed via molecular techniques, showing that virus/betasatellite was able to move to upper scion through resistant G. arboreum. However, no symptoms appeared on G. arboreum. Betasatelites were cloned and sequenced from lower scion, upper scion and G. arboreum which show that the lower scion contained both CLCuMuB and ChLCB, however only ChLCB was found in G. arboreum. The upper scion contained CLCuMuB with a deletion of 78 nucleotides (nt) in the non-coding region between Arich sequence and ${\beta}C1$ gene and insertion of 27 nt in the middle of ${\beta}C1$ ORF. This study may help in investigating molecular basis of resistance in G. arboreum.

Association between genetic polymorphisms and external apical root resorption

Shifat A Nowrin,Saidi Jaafar,Norma Ab Rahman,Rehana Basri,Mohammad Khursheed Alam,Fazal Shahid 대한치과교정학회 2018 대한치과교정학회지 Vol.48 No.6

Objective: To date, only a few studies have investigated the relationships between genetic polymorphisms and external apical root resorption (EARR). Hence, the aim of this systematic review was to explore the relationship between different gene polymorphisms and their association with EARR. Methods: A complete literature search was conducted by two independent reviewers. The PubMed, Science Direct, and Scopus databases were searched. In addition, the bibliographies of all textbooks and relevant articles were searched manually. A meta-analysis was performed using data entered into the electronic databases until February 28, 2017. Results: On the basis of the search, we identified 17 and 7 publications for the systematic review and meta-analysis, respectively. Odds ratio (OR) was used to evaluate the association of the interleukin 1B (+3954) polymorphism and the risk of EARR. The overall OR from the studies was used to estimate the risk of EARR. However, no association was found and no publication bias was apparent for the risk of EARR in patients receiving orthodontic treatment. Conclusions: More research on the relationship between gene polymorphism and EARR is necessary to determine better specificity of possible interactions.