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Dutta, N.,Sharma, K.,Hasan, Q.Z. Asian Australasian Association of Animal Productio 1999 Animal Bioscience Vol.12 No.5
The potential of Leucaena leucocephala and Prosopis cineraria leaves as nitrogen supplements ($16g/kg\;W^{0.75}/d$) to improve the utilization of a basal diet of rice straw by goats was assessed in a feeding trial. Rice straw supplementation with forage oats (Avena sativa) was fed as a control diet. DMI, $g/kgW^{0.75}$ of rice straw by goats receiving Leucaena was significantly (p<0.05) higher followed by Prosopis and oat fodder. The supplementation of Leucaena improved the digestibility coefficient of DM, OM, CP, NDF and ADF nutrient density. Goats on Prosopis or oat fodder supplemented straw responded similarly in terms of nutrient utilization. The intake ($g/kgW^{0.75}$) of DCP, TDN and nitrogen balance of goats were significantly higher (p<0.05) when Leucaena was fed. It is suggested that the Leucaena may be a useful N-supplement in areas where livestock are fed poor quality crop residues.
Jhulki, Lalmohan,Dutta, Parul,Santra, Manas Kumar,Cardoso, Marlon H.,Oshiro, Karen G. N.,Franco, Octá,vio L.,Bertolasi, Valerio,Isab, Anvarhusein A.,Bielawski, Christopher W.,Dinda, Joydev The Royal Society of Chemistry 2018 NEW JOURNAL OF CHEMISTRY Vol.42 No.16
<P>The synthesis, structures and anticancer studies of a series of precious metal complexes supported by 1-methyl-2-(phenyl)imidazo[1,5-<I>a</I>]pyridine-2-ylidene (1) have been highlighted. The Ag(i) (2), Au(i) (3) and Au(iii) (4) complexes were prepared using standard methods and characterized by a range of techniques, including NMR spectroscopy, X-ray crystallography and elemental analyses. The <I>in vitro</I> cytotoxicity activities displayed by 2-4 were explored against human colon adenocarcinoma (HCT116), lung cancer (A549) and breast cancer (MCF7) cell lines. A series of assays showed that all of the complexes exhibited significant growth inhibition in the aforementioned cell lines. Inspection of the data collected revealed that the Au(i) and Ag(i) complexes were more potent than their Au(iii) congener, a trend that was found to be consistent with molecular docking studies that utilized BCL-2 as a model as this protein regulates cell death through apoptosis.</P>
Dutta, N.,Sharma, K.,Hasan, Q.Z. Asian Australasian Association of Animal Productio 2000 Animal Bioscience Vol.13 No.4
The influence of feed allowance on intake and nutrient utilization by Barbari goats given green maize (Zea mays) and potential feeding value of left-overs were studied. The goats were offered food at 3 levels to give left-overs of about 20% (T-1), 35% (T-2) and 50% (T-3) DM of offered amount. A marked effect of refusal rate on intake and digestibility of nutrients was found. The DMI, g/kg $W^{0.75}$ increased from 39.86 in T-1 to 50.91 and 66.55 g in groups T-2 and T-3, respectively. Allowing selective consumption at higher levels (T-2 and T-3), the intake of TDN and DCP from green maize was found not only to meet the maintenance requirement but provided surplus energy and protein for substantial production. The variability in diet selectivity between goats under different treatments was pronounced. As the level of food excess increased to T-3, the left overs had a higher IVDMD and crude protein and decreased cell wall constituents (p<0.05). Considering the substantial increase in intake and digestibility from feeding green maize at high allowances to goats, further studies are needed to develop practical feeding strategies.
Dutta, N.,Sharma, K.,Hasan, Q.Z.,Pathak, N.N. Asian Australasian Association of Animal Productio 1999 Animal Bioscience Vol.12 No.5
Two experiments were conducted to determine the effect of feeding levels on intake and nutrient utilization of oat (Avena sativa) hay (OH) by goats and potential feeding value of leftovers from high levels of offer in sheep. In experiment 1, the goats (15) were offered OH at three levels of feeding to give leftovers of about 20% (T-1), 35% (T-2) and 50% (T-3) of DM offered. A marked effect of refusal rate of OH on intake and digestibility of nutrients was evident. Allowing selective consumption at higher levels (T-2 and T-3), the intake of DCP and TDN from OH was found not only to meet the maintenance requirement but provided surplus nutrients for moderate production. In experiment 2, Sheep (3) were offered one of the three dietary treatments viz OH, refusals left uneaten by goats in T-2 and T-3 (OHR) and 3% urea treated oat hay refusals (UTR) in a $3{\times}3$ latin square design. Though the potential feeding value of leftovers (OHR and UTR) was lower than OH, the results confirm the possibility of their effective use. It was concluded that feeding above the conventional ad libitum level could be an alternative to improve the performance of ruminants fed feeds like oat hay. The potential impact of the strategy would, however, depend on the effective reutilization of leftovers for feeding other animals.
Dutta, N.K.,Mazumdar, K.,Park, J.-H. Blackwell Publishing Ltd 2009 Letters in applied microbiology Vol.48 No.6
<P>Abstract</P><P>Aims: </P><P>A total of nine <I>Listeria monocytogenes</I> strains (seven serotypes) were studied to ascertain whether the non-steroidal anti-inflammatory drug diclofenac (Dc) used in combination with the conventional antilisterial antibiotic gentamicin (Gm) or ampicillin (Am) synergistically augments the efficacy of the antibiotic <I>in vitro</I>.</P><P>Methods and Results: </P><P>The effect of combination was evaluated by the checkerboard method to obtain a fractional inhibitory concentration (FIC) index followed by kill curves. Dc was synergistic with Gm (FIC 0·37) and there was indifference with Am (FIC 1) against <I>L. monocytogenes</I> ATCC 51774. The magnitude of the differences between killing by a single agent and the combination observed at 24 h was significant (<I>P</I> < 0·05) for Dc plus Gm but not Dc plus Am.</P><P>Conclusions: </P><P>Thus, the ability of extended antibiotic therapy may be improved with the help of this synergistic drug pair in listeriosis.</P><P>Significance and Impact of the Study: </P><P>Such findings may indicate parallel administration of anti-inflammatory and anti listeriosis drugs.</P>
Singh, M.,Sharma, K.,Dutta, N.,Singh, P.,Verma, A.K.,Mehra, U.R. Asian Australasian Association of Animal Productio 2007 Animal Bioscience Vol.20 No.10
A study was carried out to study the response of total purine derivatives (PD) excretion in urine to determine microbial N (MN) supply at four fixed levels of feed intake (namely 95, 80, 60 and 40% of voluntary intake). The crossbred (CB) calves were allocated according to a $4{\times}4$ Latin Square Design and fed wheat straw and concentrate (1:1). The rate of PD excretion (mmol/d) as a linear function of feed intake was 15.85/kg DMI and 20.12/kg DOMI. Based on the endogenous and PD excretion rates obtained in this study, a relationship between daily urinary PD excretion (Y, mmol) and daily microbial protein supply (X, mmol) was developed for crossbred calves as Y = 0.83X+0.296 kg $W^{0.75}$. The derived microbial N values using this equation differed (p<0.001) among the 4 groups and was the highest in L-95 followed by L-80, L-60 and L-40. The relationship between urinary nitrogen loss (Y, g/d) and DOMI (X, kg/d) was established as: Y = 6.038X+21.753 ($r^2$ = 0.663, p<0.01). When urinary excretion of PD (Y, mmol/d) was plotted against intake of DM and DOM (X, kg/d), the equations obtained were: Y = 7.1711X+8.674 ($r^2$ = 0.889, p<0.01) and Y = 12.434X+7.683 ($r^2$ = 0.896, p<0.01), respectively. The proportional contribution of allantoin and uric acid to total PD remained stable irrespective of level of feed intake. Similarly, urinary excretion of creatinine did not differ (p>0.05) between animals fed at different levels. The MN supply was the highest to animals at intake levels L-95, and decreased linearly with corresponding decrease in feed intake. However, the MN supply when expressed per kg DOMI remained statistically (p>0.05) similar irrespective of level of intake. The results revealed that the excretion of urinary purine derivatives were positively correlated with the level of feed intake as well as rumen microbial supply and thus it could be a good indicator for measuring the microbial protein supply and nutritional status of animals.
Dutta, S.,Ghatak, K.L.,Ganguly, S.N. The Korean Society of Pharmacognosy 1997 Natural Product Sciences Vol.3 No.2
A new pentacyclic triterpene acid, elliptic acid was isolated from the ethanolic extract of the leaves of Rubus ellipticus. On the basis of physical evidences coupled with chemical investigations, the structure of elliptic acid was given as, 3,7, 11-trihydroxy ursolic acid.
N. P. Maity,Reshmi Maity,Subir Dutta,Subhasish Deb,K. Girija Sravani,K. Srinivasa Rao,S. Baishya 한국전기전자재료학회 2020 Transactions on Electrical and Electronic Material Vol.21 No.3
Surface potential and drain current models for a physically based double halo metal–oxide–semiconductor-fi eld-eff ect-transistor(MOSFET) are reported. The proposed models have been established in sub-threshold mode of MOSFET operation. The depletion layer depth used in the pseudo two dimensional Poisson’s equation comprises the effect of two symmetrical pocket implantations at both the ends of the channel region. In this effort, improvement in the investigation is brought in by taking lateral asymmetric channel owing to non-uniform doping. The conventional silicon-dioxide (SiO2) material is replaced with a promising high-k dielectric material hafnium oxide (HfO2) to analyze the surface potential and drain current models. Analytical results have been compared using Synopsys technology computer aided design (TCAD). Excellent conformities between the analytical models and simulations are observed.
Bi-Event Subtraction Technique at hadron colliders
Dutta, B.,Kamon, T.,Kolev, N.,Krislock, A. North-Holland Pub. Co 2011 Physics letters: B Vol.703 No.4
We propose the Bi-Event Subtraction Technique (BEST) as a method of modeling and subtracting large portions of the combinatoric background during reconstruction of particle decay chains at hadron colliders. The combinatoric background arises when it is impossible to know experimentally which observed particles come from the decay chain of interest. The background shape can be modeled by combining observed particles from different collision events and be subtracted away, greatly reducing the overall background. This idea has been demonstrated in various experiments in the past. We generalize it by showing how to apply BEST multiple times in a row to fully reconstruct a cascade decay. We show the power of BEST with two simulated examples of its application towards reconstruction of the top quark and a supersymmetric decay chain at the Large Hadron Collider.