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Dongbo Liu,Chengchuan An,Muhammad Yasir,Jian Lu,Jingxin Xia 대한토목학회 2022 KSCE JOURNAL OF CIVIL ENGINEERING Vol.26 No.5
Real-time and accurate queue length information is crucial to developing effective queue management applications in modern traffic control systems to alleviate traffic congestion. A Random Forests (RF) based real-time queue length estimation method is proposed using the vehicle Global Position System (GPS) trajectory and License Plate Recognition (LPR ) Data. The RF model is trained to predict the vehicle stop locations provided by the GPS data by features of traffic flow characteristics extracted from the LRP data. The predicted stop locations are further used to estimate the cyclic maximum queue length for each approach lane. The proposed method has been implemented on sixteen lanes of eight links from both major and minor arterials in Kunshan City, China. Key findings and conclusions include: 1) By feature selection, the travel time has the most significant impact on the prediction accuracy of the vehicle stop location, and the number of departed vehicles is the secondary informative feature. 2) The RF model achieves a satisfying accuracy for the stop location prediction and cyclic maximum queue length estimation, which has the best performance with a larger sample size in the training data. 3) Comparative analysis also shows the superiorities of the proposed model to have more accurate results by incorporating comprehensive features and a machine learning process.
Scheduling Performance Analysis on Parameter Sweep Applications in Cloud Environments
Ning Han,Dongbo Liu 보안공학연구지원센터 2016 International Journal of Grid and Distributed Comp Vol.9 No.4
Recently, cloud computing has becoming a promising networking infrastructure paradigm which enable us to deploy large-scale applications in a cost-effective manner. However, many existing cloud platforms are designed for supporting commercial applications instead of large-scale scientific computing workloads. As a result, the effectiveness of running such kind of applications on cloud platforms is still an opening issue, especially when the performance penalties introduced by virtualization technology is taken into consideration. In this work, we take effects on analyzing the scheduling performance of cloud platforms for Parameter Sweep Applications (PSA), which is one of most used program models in large-scale scientific computing applications. All the experiments are conducted on our integrated performance evaluation middleware. The experimental results indicate that many conventional scheduling algorithms which are effective in classic distributed systems (i.e. grid, cluster) need to take into account the negative effects introduced by virtualization technology. In addition, the experimental results also indicate some useful hints for improving the scheduling performance of PSA workloads in cloud environments.
Degradation Characteristics and Metabolic Pathway of 17β-estradiol (E2) by Rhodococcus sp. DS201
Qingmiao Yu,Ping Wang,Dongbo Liu,Ruixia Gao,Huanhuan Shao,Hongyan Zhao,Zhe Ma,Dan Wang,Hongliang Huo 한국생물공학회 2016 Biotechnology and Bioprocess Engineering Vol.21 No.6
In this study an E2-degrading bacterium was isolated from the activated sludge of a municipal treatment plant that treats the waste from a contraceptive medicineprocessing factory in Beijing, China. Using the observed morphological and physiological features of the bacterium and 16S rRNA sequence analysis, this bacterial strain was identified as Rhodococcus sp. DS201. Using single-factor experiments and orthogonal tests, it was demonstrated that, when strain DS210 bacteria were inoculated into MM medium at an initial concentration of 1 mg/L with an initial pH of 7 and an inoculum amount of 1%, complete degradation of E2 by this strain was achieved within 3 days at 30oC. After strain DS201 had degraded the E2, several E2 metabolites were detected in the culture extracts using high-performance liquid chromatography (HPLC); they were then further identified using HPLC with tandem mass spectrometry (LC-MS/MS). Mass spectrum analysis of the E2 degradation identified the following products: pent- 4-enoic acid; 2-ethyl-3-hydroxy-6-methylcyclohexane-1- carboxylic acid; 3-(7a-methyl-1,5-dioxooctahydro-1H-inden- 4-yl) propanoic acid; and 5-hydroxy-4-(3-hydroxypropyl)- 7a-methyloctahydro-1H-inden-1-one. These products have not previously been reported as parts of a mechanism for microbial E2 degradation and were suspected to be new metabolite products. Therefore, the E2 degradation pathway by strain DS201 is proposed herein.
Zheng Wang,Yanni Liang,Dongbo Zhang,Xue Wu,Jingao Yu,Zhen Zhang,Yi Li,Chen Sun,Zhishu Tang,Li Liu 한국식품영양과학회 2020 Journal of medicinal food Vol.23 No.2
Polysaccharide from Ma-chi-xian (Portulacae oleracea L., POLP) was prepared and the therapeutic effect on dextran sodium sulfate-induced colitis mice was investigated in this study. The results of clinical activity score and H&E staining confirmed the therapeutic effect of POLP. POLP could diminished the symptoms of colitis and improve colon histopathological structure of the colitis mice. The expression levels of four cytokines were determined. The concentrations of PGE2 and IL-6 were downregulated by POLP treatment. The COX-2 protein expression levels and the STAT3 phosphorylation levels were detected. The results showed that these two protein levels were all increased in colitis and decreased after POLP treatment, indicating that these two proteins were closely related with the protective effect of POLP. Because the synthesis of PGE2 is catalyzed by COX-2 and phosphorylation of STAT3 can induce the expression of COX-2, it was concluded that STAT3 was a key protein related to the POLP exerting its activity in colitis.
Analysis of mechanical contact behavior between the catheter and trachea tissue during bronchoscopy
Yudong Bao,Shengqian Qu,Dongbo Qi,Wen Wei,Yang Zhan,Hejun Liu 대한기계학회 2023 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.37 No.3
As for the contact mechanics between the catheter and trachea tissue during bronchoscopy, the anterior and curved part of the catheter were selected for analysis. The material parameters of each sample were obtained by uniaxial tensile experiments. And this paper verified the stress changes during the contact process using ABAQUS software from three aspects: different material property parameters, contact angle, and catheter bending angle. The results show that: when the characteristic parameter is 90°, the force on the trachea is minimal. And the force changes in a small range when the contact angle is kept at 45°-75°. When the catheter enters the next level of the trachea, the bending part is in contact with the trachea wall. At this time, keeping the bending angle at 15°-30° helps to reduce the contact force. This study could provide a theoretical basis for surgical instruments' interventional therapy.