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      • SCISCIESCOPUS

        The 13th Data Release of the Sloan Digital Sky Survey: First Spectroscopic Data from the SDSS-IV Survey Mapping Nearby Galaxies at Apache Point Observatory

        Albareti, Franco D.,Prieto, Carlos Allende,Almeida, Andres,Anders, Friedrich,Anderson, Scott,Andrews, Brett H.,Aragó,n-Salamanca, Alfonso,Argudo-Ferná,ndez, Maria,Armengaud, Eric,Aubourg, American Astronomical Society 2017 The Astrophysical journal Supplement series Vol.233 No.2

        <P>The fourth generation of the Sloan Digital Sky Survey (SDSS-IV) began observations in 2014 July. It pursues three core programs: the Apache Point Observatory Galactic Evolution Experiment 2 (APOGEE-2), Mapping Nearby Galaxies at APO (MaNGA), and the Extended Baryon Oscillation Spectroscopic Survey (eBOSS). As well as its core program, eBOSS contains two major subprograms: the Time Domain Spectroscopic Survey (TDSS) and the SPectroscopic IDentification of ERosita Sources (SPIDERS). This paper describes the first data release from SDSS-IV, Data Release 13 (DR13). DR13 makes publicly available the first 1390 spatially resolved integral field unit observations of nearby galaxies from MaNGA. It includes new observations from eBOSS, completing the Sloan Extended QUasar, Emission-line galaxy, Luminous red galaxy Survey (SEQUELS), which also targeted variability-selected objects and X-ray-selected objects. DR13 includes new reductions of the SDSS-III BOSS data, improving the spectrophotometric calibration and redshift classification, and new reductions of the SDSS-III APOGEE-1 data, improving stellar parameters for dwarf stars and cooler stars. DR13 provides more robust and precise photometric calibrations. Value-added target catalogs relevant for eBOSS, TDSS, and SPIDERS and an updated red-clump catalog for APOGEE are also available. This paper describes the location and format of the data and provides references to important technical papers. The SDSS web site, http://www.sdss.org, provides links to the data, tutorials, examples of data access, and extensive documentation of the reduction and analysis procedures. DR13 is the first of a scheduled set that will contain new data and analyses from the planned similar to 6 yr operations of SDSS-IV.</P>

      • Temperature-responsive bioactive hydrogels based on a multifunctional recombinant elastin-like polymer

        Santo, Vitor E.,Prieto, Susana,Testera, Ana M.,Arias, Francisco J.,Alonso, Matilde,Mano, Joao F.,Rodriguez-Cabello, Jose Carlos Techno-Press 2015 Biomaterials and biomedical engineering Vol.2 No.1

        A bioactive and multifunctional elastin-like polymer (ELP) was produced by genetic engineering techniques to develop new artificial matrices with the ability to mimic the extracellular matrix (ECM). The basic composition of this ELP is a thermo- and pH-sensitive elastin pentapeptide which has been enriched with RGD-containing domains, the RGD loop of fibronectin, for recognition by integrin receptors on their sequence to promote efficient cell attachment. Hydrogels of this RGD-containing polymer were obtained by crosslinking with hexamethylene diisocyanate, a lysine-targeted crosslinker. These materials retain the "smart" nature and temperature-responsive character, and the desired mechanical behavior of the elastin-like polymer family. The influence of the degree of crosslinking on the morphology and properties of the matrices were tested by calorimetric techniques and scanning electron microscopy (SEM). Their mechanical behavior was studied by dynamical mechanical analysis (DMA). These results show the potential of these materials in biomedical applications, especially in the development of smart systems for tissue engineering.

      • Temperature-responsive bioactive hydrogels based on a multifunctional recombinant elastin-like polymer

        Santo, Vitor E.,Prieto, Susana,Testera, Ana M.,Arias, Francisco J.,Alonso, Matilde,Mano, Joao F.,Rodriguez-Cabello, Jose Carlos Techno-Press 2015 Biomaterials and Biomechanics in Bioengineering Vol.2 No.1

        A bioactive and multifunctional elastin-like polymer (ELP) was produced by genetic engineering techniques to develop new artificial matrices with the ability to mimic the extracellular matrix (ECM). The basic composition of this ELP is a thermo- and pH-sensitive elastin pentapeptide which has been enriched with RGD-containing domains, the RGD loop of fibronectin, for recognition by integrin receptors on their sequence to promote efficient cell attachment. Hydrogels of this RGD-containing polymer were obtained by crosslinking with hexamethylene diisocyanate, a lysine-targeted crosslinker. These materials retain the "smart" nature and temperature-responsive character, and the desired mechanical behavior of the elastin-like polymer family. The influence of the degree of crosslinking on the morphology and properties of the matrices were tested by calorimetric techniques and scanning electron microscopy (SEM). Their mechanical behavior was studied by dynamical mechanical analysis (DMA). These results show the potential of these materials in biomedical applications, especially in the development of smart systems for tissue engineering.

      • KCI등재후보

        Serum Sclerostin in Hepatitis C Virus Infected Patients

        E. González-Reimers,Javier López-Prieto,Ricardo Pelazas-González,M.Remedios Alemán-Valls,María José de la Vega-Prieto,Carlos Jorge-Ripper,M. Carmen Durán-Castellón,F Santolaria-Fernández 대한골대사학회 2014 대한골대사학회지 Vol.21 No.1

        Background: Sclerostin inhibits osteoblast functions, differentiations, and survival rates. As an endogenous inhibitor of the Wnt/β-catenin pathway, the sclerostin should be re-lated to decreased bone masses, although several studies indicate opposite results. Inaddition, it may be related to insulin resistances and carbohydrate metabolisms, a rela-tion shared with other markers of bone metabolisms, such as osteocalcin. Hepatitis C vi-rus (HCV) infected patients may present osteoporosis, and frequently show liver steato-sis, which is a consequence of insulin resistance. The behaviour of sclerostin in these pa-tients is yet unknown. The aim of this work is to analyse the relationships between se-rum sclerostin and osteocalcin levels and bone mineral density (BMD), liver functions,the intensity of liver steatosis and biochemical markers of bone homeostasis and insulinresistance in HCV-infected patients. Methods: Forty HCV patients with 20 years of ageand gender-matching controls were included in this study and underwent bone densi-tometry. Serum sclerostin, osteocalcin, collagen telopeptide, adiponectin, leptin, insulin,resistin, tumor necrosis factor (TNF)-α, and interleukin (IL)-6 were determined. Liver fatwas histomorphometrically assessed. Results: Sclerostin levels were slightly higher inpatients than in controls, and were directly related to BMD at different parts of the skele-ton, also to the serum telopeptide, and to the liver steatosis and TNF-α. On the contrary,osteocalcin showed a significant direct relationship with serum adiponectin, and an in-verse one with IL-6. Conclusions: Serum sclerostin levels were within the normal rangein HCV patients, and correlated directly with BMD and serum telopeptide. In addition,the relationships of sclerostin and osteocalcin with variables associated with insulin re-sistance suggested the role of bones for intermediary metabolisms.

      • KCI등재

        Adaptation and Cross-Adaptation of Listeria monocytogenes and Salmonella enterica to Poultry Decontaminants

        Alicia Alonso-Hernando,Rosa Capita,Miguel Prieto,Carlos Alonso-Calleja 한국미생물학회 2009 The journal of microbiology Vol.47 No.2

        Information on the potential for acquired reduced susceptibility of bacteria to poultry decontaminants occurring is lacking. Minimal Inhibitory Concentrations (MICs) were established for assessing the initial susceptibility and the adaptative and cross-adaptative responses of four bacterial strains (Listeria monocytogenes serovar 1/2a, L. monocytogenes serovar 4b, Salmonella enterica serotype Typhimurium, and S. enterica serotype Enteritidis) to four poultry decontaminants (trisodium phosphate, acidified sodium chlorite -ASC-, citric acid, and peroxyacetic acid). The initial susceptibility was observed to differ among species (all decontaminants) and between Salmonella strains (ASC). These inter- and intra-specific variations highlight (1) the need for strict monitoring of decontaminant concentrations to inactivate all target pathogens of concern, and (2) the importance of selecting adequate test strains in decontamination studies. MICs of ASC (0.17±0.02 to 0.21±0.02 mg/ml) were higher than the U.S. authorized concentration when applied as a pre-chiller or chiller solution (0.05 to 0.15 mg/ml). Progressively increasing decontaminant concentrations resulted in reduced susceptibility of strains. The highest increase in MIC was 1.88 to 2.71-fold (ASC). All decontaminants were shown to cause cross-adaptation of strains between both related and unrelated compounds, the highest increase in MIC being 1.82-fold (ASC). Our results suggest that the in-use concentrations of ASC could, in certain conditions, be ineffective against Listeria and Salmonella strains. The adaptative and cross-adaptative responses of strains tested to poultry decontaminants are of minor concern. However, the observations being presented here are based on in vitro studies, and further research into practical applications are needed in order to confirm these findings.

      • SCISCIESCOPUS

        THE ELEVENTH AND TWELFTH DATA RELEASES OF THE SLOAN DIGITAL SKY SURVEY: FINAL DATA FROM SDSS-III

        Alam, Shadab,Albareti, Franco D.,Prieto, Carlos Allende,Anders, F.,Anderson, Scott F.,Anderton, Timothy,Andrews, Brett H.,Armengaud, Eric,Aubourg, É,ric,Bailey, Stephen,Basu, Sarbani,Bautista, J IOP Publishing 2015 The Astrophysical journal Supplement series Vol.219 No.1

        <P>The third generation of the Sloan Digital Sky Survey (SDSS-III) took data from 2008 to 2014 using the original SDSS wide-field imager, the original and an upgraded multi-object fiber-fed optical spectrograph, a new near-infrared high-resolution spectrograph, and a novel optical interferometer. All of the data from SDSS-III are now made public. In particular, this paper describes Data Release 11 (DR11) including all data acquired through 2013 July, and Data Release 12 (DR12) adding data acquired through 2014 July (including all data included in previous data releases), marking the end of SDSS-III observing. Relative to our previous public release (DR10), DR12 adds one million new spectra of galaxies and quasars from the Baryon Oscillation Spectroscopic Survey (BOSS) over an additional 3000 deg(2) of sky, more than triples the number of H-band spectra of stars as part of the Apache Point Observatory (APO) Galactic Evolution Experiment (APOGEE), and includes repeated accurate radial velocity measurements of 5500 stars from the Multi-object APO Radial Velocity Exoplanet Large-area Survey (MARVELS). The APOGEE outputs now include the measured abundances of 15 different elements for each star. In total, SDSS-III added 5200 deg(2) of ugriz imaging; 155,520 spectra of 138,099 stars as part of the Sloan Exploration of Galactic Understanding and Evolution 2 (SEGUE-2) survey; 2,497,484 BOSS spectra of 1,372,737 galaxies, 294,512 quasars, and 247,216 stars over 9376 deg(2); 618,080 APOGEE spectra of 156,593 stars; and 197,040 MARVELS spectra of 5513 stars. Since its first light in 1998, SDSS has imaged over 1/3 of the Celestial sphere in five bands and obtained over five million astronomical spectra.</P>

      • SCISCIESCOPUS
      • KCI등재

        High Temperature Ferromagnetism in Mn Based Multilayers of Wide Gap Semiconductors: Mn/ZnO and Mn/SnO2: The Role of Interfaces

        Ana Espinosa,Eva C espedes,Carlos Prieto,Mar Garcia-Hernandez,Alicia de Andres 한국물리학회 2008 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.52 No.5

        We have investigated magnetic, electronic and structural properties of two series of multilayers, (Mn(d)/ZnO(₃ nm))N and (Mn(d)/SnO₂(₃nm))N, deposited onto Si(100) using magnetron sputtering. The nominal Mn layer thickness, d, ranged from 10 to 0.2 nm and the number of layers, N, was increased to keep the total amount of Mn constant. Structural information was deduced from X- ray re ectivity and XAS and Mn oxidation state is estimated from its K edge. The ferromagnetic transition temperature, TC, in those samples where a ferromagnetic order is established, is always above 400 K. The ferromagnetic fraction within each sample evidences an opposite behaviour as Mn layer thickness is reduced and N increased, in ZnO and SnO₂ series. While ferromagnetism is favoured in Mn/ZnO increasing d, the maximum value, in Mn/SnO₂, is obtained for 0.4 nm Mn layers. A Mn mixed valence state is not a sucient condition for ferromagnetism. We discuss the origin of this opposite behaviour which is related to the particular phases formed at the interfaces related to the dierent ability of ZnO and SnO₂ to participate and saturate Mn oxide phases. We have investigated magnetic, electronic and structural properties of two series of multilayers, (Mn(d)/ZnO(₃ nm))N and (Mn(d)/SnO₂(₃nm))N, deposited onto Si(100) using magnetron sputtering. The nominal Mn layer thickness, d, ranged from 10 to 0.2 nm and the number of layers, N, was increased to keep the total amount of Mn constant. Structural information was deduced from X- ray re ectivity and XAS and Mn oxidation state is estimated from its K edge. The ferromagnetic transition temperature, TC, in those samples where a ferromagnetic order is established, is always above 400 K. The ferromagnetic fraction within each sample evidences an opposite behaviour as Mn layer thickness is reduced and N increased, in ZnO and SnO₂ series. While ferromagnetism is favoured in Mn/ZnO increasing d, the maximum value, in Mn/SnO₂, is obtained for 0.4 nm Mn layers. A Mn mixed valence state is not a sucient condition for ferromagnetism. We discuss the origin of this opposite behaviour which is related to the particular phases formed at the interfaces related to the dierent ability of ZnO and SnO₂ to participate and saturate Mn oxide phases.

      • SCISCIESCOPUS

        Sloan Digital Sky Survey IV: Mapping the Milky Way, Nearby Galaxies, and the Distant Universe

        Blanton, Michael R.,Bershady, Matthew A.,Abolfathi, Bela,Albareti, Franco D.,Prieto, Carlos Allende,Almeida, Andres,Alonso-Garcí,a, Javier,Anders, Friedrich,Anderson, Scott F.,Andrews, Brett,Aqu American Institute of Physics 2017 The Astronomical journal Vol.154 No.1

        <P>We describe the Sloan Digital Sky Survey IV (SDSS-IV), a project encompassing three major spectroscopic programs. The Apache Point Observatory Galactic Evolution Experiment 2 (APOGEE-2) is observing hundreds of thousands of Milky Way stars at high resolution and. high signal-to-noise ratios in the near-infrared. The Mapping Nearby Galaxies at Apache Point Observatory (MaNGA) survey is obtaining spatially resolved spectroscopy for thousands of nearby galaxies (median z similar to 0.03). The extended Baryon Oscillation Spectroscopic Survey (eBOSS) is mapping the galaxy, quasar, and neutral gas distributions between z similar to 0.6 and 3.5 to constrain cosmology using baryon acoustic oscillations, redshift space distortions, and the shape of the power spectrum. Within eBOSS, we are conducting two major subprograms: the SPectroscopic IDentification of eROSITA Sources (SPIDERS), investigating X-ray AGNs. and galaxies in X-ray clusters, and the Time Domain Spectroscopic Survey (TDSS), obtaining spectra of variable sources. All programs use the 2.5 m Sloan Foundation Telescope at the. Apache Point Observatory; observations there began in Summer 2014. APOGEE-2 also operates a second near-infrared spectrograph at the 2.5 m du Pont Telescope at Las Campanas Observatory, with observations beginning in early 2017. Observations at both facilities are scheduled to continue through 2020. In keeping with previous SDSS policy, SDSS-IV provides regularly scheduled public data releases; the first one, Data Release 13, was made available in 2016 July.</P>

      • A simple means of producing highly transparent graphene on sapphire using chemical vapor deposition on a copper catalyst

        Anemone, Gloria,Climent-Pascual, Esteban,Al Taleb, Amjad,Yu, Hak Ki,Jimé,nez-Villacorta, Felix,Prieto, Carlos,Wodtke, Alec M.,De André,s, Alicia,Farí,as, Daniel Elsevier 2018 Carbon Vol.139 No.-

        <P><B>Abstract</B></P> <P>Chemical vapor deposition (CVD) is one of the best ways to scalably grow low cost, high quality graphene on metal substrates; unfortunately, it not ideal for producing graphene on dielectric substrates. Here, we demontrate production of a high quality graphene layer on Sapphire using CVD with a copper catalyst. The catalyst consists of a thin copper film grown epitaxially on <I>α</I>- <SUB> Al 2 </SUB> <SUB> O 3 </SUB> (0001). After CVD growth of Graphene, the copper can be removed by simple evaporation in the presence of a carbon source ( <SUB> C 2 </SUB> <SUB> H 4 </SUB> ). We characterized the resulting graphene layer using Raman spectroscopy, atomic force microscopy (AFM), optical transmission and helium atom scattering (HAS). The sample exhibited a reduced Raman D peak and an excellent 2D to G ratio. AFM and HAS show large graphene domains over a macroscopic region. We measured > 86 % transparency over the visible spectrum.</P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

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