http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
OrCanome: a Comprehensive Resource for Oral Cancer
Bhartiya, Deeksha,Kumar, Amit,Singh, Harpreet,Sharma, Amitesh,Kaushik, Anita,Kumari, Suchitra,Mehrotra, Ravi Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.3
Oral cancer is one of the most prevalent cancers in India but the underlying mechanisms are minimally unraveled. Cancer research has immensely benefited from genome scale high throughput studies which have contributed to expanding the volume of data. Such datasets also exist for oral cancer genes but there has been no consolidated approach to integrate the data to reveal meaningful biological information. OrCanome is one of the largest and comprehensive, user-friendly databases of oral cancer. It features a compilation of over 900 genes dysregulated in oral cancer and provides detailed annotations of the genes, transcripts and proteins along with additional information encompassing expression, inhibitors, epitopes and pathways. The resource has been envisioned as a one-stop solution for genomic, transcriptomic and proteomic annotation of these genes and the integrated approach will facilitate the identification of potential biomarkers and therapeutic targets.
3.5 ㎓ High Power Pulsed Microwaves irradiated solutions and their biological evaluation
Pradeep Bhartiya,Sohail Mumtaz,Nagendra Kaushik,Eun Ha Choi 한국진공학회 2021 한국진공학회 학술발표회초록집 Vol.2021 No.2
Microwaves are used frequently for domestic, industrial and military purposes. This study is focused to investigate the cellular effects of 3.5 GHz pulsed high-power pulsed microwave radiation-irradiated liquid solutions on the functions and survival of human cancer and normal cells. We used different physiological solutions such as phosphate buffer saline, deionized water, and Dulbecco’s modified Eagle medium (DMEM) commonly used for cell culture growth which were irradiated with high power pulsed microwave radiation (45 shots with energy of 1 J/shot). We observed changes in metabolic viability, cell death and cell cycle alterations in cells treated with high power pulsed microwaves irradiated liquid solutions.
Linh Nhat Nguyen,Neha Kaushik,Pradeep Bhartiya,Sintayehu Kebede Gurmessa,김화정,Liem Quang Nguyen,Nagendra Kumar Kaushik,최은하 한국공업화학회 2021 Journal of Industrial and Engineering Chemistry Vol.100 No.-
The development of an efficient tumor-specific therapeutic approach, which functions against theprimary tumor and also repairs the host immune system to eradicate distant tumors, remains a clinicalissue. Herein, this study focuses on the use of polydopamine-coated gold nanoparticles (Au@PDA NPs)that showed excellent selectivity towards cancer cells. The Au@PDA NPs were prepared by a plasmasynthesis method with a short reaction time and minimize the use of chemicals. Prominently, Au@PDANPs not only exhibited high cellular internalization but also stimulated immunogenic cell death (ICD) inaggressive breast carcinoma cells. Moreover, it was observed that damage-associated molecular patterns(DAMPs) were released by damaged cells together with the autophagy process after Au@PDA NPsexposure, which acted as endogenous danger signals to regulate the consequent immune response. Thisstudy highlights the novel mechanism of Au@PDA NPs-triggered anti-tumor immunity againstimmunosuppressive cancers, demonstrated the potential of the Au@PDA NPs for cancer immunotherapy.
Ruthenium doped carbon aerogel with CO2 surface activation for enhanced electrochemical capacitance
Ashish Singh,D.K. Kohli,Sushmita Bhartiya,Rashmi Singh,M.K. Singh,P.K. Gupta 한국물리학회 2017 Current Applied Physics Vol.17 No.6
With the aim of enhancement of electrochemical capacitance, CO2 activation of carbon aerogel (CA) prepared by polycondensation of resorcinol with formaldehyde was performed to obtain activated carbon aerogel (ACA) having improved surface area properties. Ruthenium oxide nano-particles were loaded by impregnation method for utilizing pseudo-capacitive property of ruthenium oxide (RuO2) and the effect of activation treatment was studied. RuO2 loading of 20% by weight was accomplished in CA and ACA to synthesize RuO2 doped carbon aerogel (CA/RuO2) and activated carbon aerogel (ACA/RuO2). While the specific capacitance of carbon aerogel improved from 95 to 153 F/g on activation, RuO2 loading further led to enhancement in capacitance and specific capacitance of 308 F/g was obtained for ACA/ RuO2. The studies being important for Ru economy, showed the influence of surface area enhancement of base matrix in achieving high specific capacitance.
Singh, Ashish,Kohli, D.K.,Singh, Rashmi,Bhartiya, Sushmita,Singh, M.K.,Karnal, A.K. The Korean Electrochemical Society 2021 Journal of electrochemical science and technology Vol.12 No.2
We report, synthesis of high surface area composite carbon aerogel using additive based polymerization technique by incorporating graphitic porous carbon as additive. This additive was separately prepared using sol-gel polymerization of resorcinol-furfuraldehyde in iso-propyl alcohol medium at much above the routine gelation temperature to yield porous carbon (CA-IPA) having graphitic layered morphology. CA-IPA exhibited a unique combination of meso-pore dominated surface area (~ 700 m<sup>2</sup>/g) and good conductivity of ~ 300 S/m. The composite carbon aerogel (CCA) was synthesized by traditional aqueous medium based resorcinol-formaldehyde gelation with CA-IPA as additive. The presence of CA-IPA favored enhanced meso-porosity as well as contributed to improvement in bulk conductivity. Based on the surface area characteristics, CCA-8 composition having 8% additive was found to be optimum. It showed specific surface area of ~ 2056 m<sup>2</sup>/g, mesopore area of 827 m<sup>2</sup>/g and electrical conductivity of 180 S/m. The electrode formed with CCA-8 showed improved electrochemical behavior, with specific capacitance of 148 F/g & ESR < 1 Ω, making it a better choice as super capacitor for energy storage applications.
Sikka Kapil,Yogal Rijendra,Thakar Alok,Kumar Rakesh,Chaudhary Tanvi,Bhartiya Mao,Verma Hitesh,Sharma Sonam,Singh Chirom Amit 대한청각학회 2022 Journal of Audiology & Otology Vol.26 No.4
Background and Objectives: Single-sided deafness (SSD) leads to non-participation of the diseased ear in generating adequate auditory input, which results in poor speech discrimination in noisy surroundings. The present study objectively compared the audiological benefits rendered by contralateral routing of signal (CROS) hearing aid and bone conduction device (BCD) in patients with SSD >70 dB HL using the modified hearing in noise test (HINT).Materials and Methods: Patients with SSD >70 dB HL in poor and clinically normal hearing in the better ear were enrolled. Patients aged <18 or >70 years, with a history of neurological insult or ear infection in the last 3 months, mental retardation, psychiatric or developmental disorders, and diabetes were excluded. Modified HINT was performed with the affected ear unaided, aided with CROS hearing aid, and with BCD, generating three groups. Noise signal was presented at a fixed intensity of 65 dB at the neutral position in the center and speech signal was presented to either ear sequentially. The test was repeated with the speech signal fixed at the neutral position and the noise signal presented to either ear.Results: BCD led to a better signal-to-noise ratio (SNR) than CROS hearing aid in all situations except when noise was centralized and speech was presented to the affected ear.Conclusions: A benefit was observed when auditory rehabilitation was used for the affected ear as demonstrated by better SNR scores. The results showed that BCD performed better than CROS hearing aid.