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Ahmad, Bashir,Gul, Bushra,Ali, Sajid,Bashir, Shumaila,Mahmood, Nourin,Ahmad, Jamshed,Nawaz, Seema Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.11
Background: Due to the increase in morbidity and mortality rate, cancer has become an alarming threat to the human population worldwide. Since cancer is a progressive disorder, timely diagnosis would be helpful to prevent/stop cancer from progressing to severe stage. In Khyber Pakhtunkhwa, Pakistan, most of the time, tumors are diagnosed with endoscopy and biopsy; therefore rare studies exist regarding the diagnosis of gastrointestinal (GIT) carcinomas based on tumor markers, especially CEA. Objectives: This study made a comparative analysis of CEA in admitted hospitalized stomach and colon cancer patients diagnosed as GIT with biopsy. Materials and Methods: In this study, a total of 66 cases were included. The level of CEA was determined in the blood of these patients using ELISA technique. Results: Out of 66 patients, the level of CEA was high in 59.1% of the total, 60.7% in colon cancer patients and 57.9 % in stomach cancer patients. Moreover, the incidence of colorectal and stomach cancer was greater in males as compared to females. Patients were more of the age group of 40-60 and the level of CEA was comparatively higher in patients (51.5%) with histology which was moderately differentiated, than patients with well differentiated and poorly differentiated tumor histology. Conclusions: CEA level was high in more than 50% of the total patients. Moreover, CEA exhibited higher sensitivity for colon than stomach cancer.
Allgrove (Triple A) Syndrome: A Case Report from the Kashmir Valley
Raiz Ahmad Misgar,Nazir Ahmad Pala,Mahroosa Ramzan,Arshad Iqbal Wani,Mir Iftikhar Bashir,Bashir Ahmad Laway 대한내분비학회 2015 Endocrinology and metabolism Vol.30 No.4
Allgrove (Triple A) syndrome is a rare autosomal recessive disorder characterized by cardinal features of adrenal insufficiency due to adrenocorticotropic hormone (ACTH) resistance, achalasia, and alacrimia. It is frequently associated with neurological manifestations like polyneuropathy. Since its first description by Allgrove in 1978, approximately 100 cases have been reported in the literature. Here we report an 18-year-old boy diagnosed as having Allgrove syndrome, with ACTH resistant adrenal insufficiency, achalasia, alacrimia, and severe motor polyneuropathy. Alacrimia was the earliest feature evident at the age of 8 years. He presented with achalasia and adrenal insufficiency at 12 and 18 years respectively and developed neurological symptoms in the form of severe muscle wasting at the age of 15 years. Patients with Allgrove syndrome usually manifest adrenal insufficiency and achalasia during first decade of life. Our patient manifested adrenal insufficiency and achalasia in the second decade and manifested neurological dysfunction before adrenal dysfunction.
Bashir Ahmad,Ahmed Alsaedi,Doa'A Garout 대한수학회 2008 대한수학회지 Vol.45 No.5
In this paper, we consider an impulsive nonlinear second order ordinary differential equation with nonlinear three-point boundary conditions and develop a monotone iteration scheme by relaxing the convexity assumption on the function involved in the differential equation and the concavity assumption on nonlinearities in the boundary conditions. In fact, we obtain monotone sequences of iterates (approximate solutions) converging quadratically to the unique solution of the impulsive three-point boundary value problem. In this paper, we consider an impulsive nonlinear second order ordinary differential equation with nonlinear three-point boundary conditions and develop a monotone iteration scheme by relaxing the convexity assumption on the function involved in the differential equation and the concavity assumption on nonlinearities in the boundary conditions. In fact, we obtain monotone sequences of iterates (approximate solutions) converging quadratically to the unique solution of the impulsive three-point boundary value problem.
EXISTENCE RESULTS FOR FRACTIONAL DIFFERENTIAL INCLUSIONS WITH SEPARATED BOUNDARY CONDITIONS
Bashir Ahmad 대한수학회 2010 대한수학회보 Vol.47 No.4
In this paper, we apply Bohnenblust-Karlins fixed point theorem to prove the existence of solutions for a class of fractional differential inclusions with separated boundary conditions. Some applications of the main result are also presented.
Ahmad, Bashir,Shrivastava, Vinoy K.,Saleh, Ramadan,Henkel, Ralf,Agarwal, Ashok The Korean Society for Reproductive Medicine 2018 Clinical and Experimental Reproductive Medicine Vol.45 No.4
Objective: Zearalenone (ZEA) is a mycotoxin with potent estrogenic effects. Saffron is an herbal product that has antioxidant activities. The objective of this study was to investigate the protective role of saffron against reproductive toxicity induced by ZEA in female mice. Methods: Ninety 8-week-old female mice were randomly allocated into three treatment groups. The first group received an intraperitoneal injection of ZEA (2.5 mg/kg) on alternate days. The second group received ZEA (2.5 mg/kg) on alternate days plus oral saffron daily (50 mg/kg). The third group was treated with a vehicle of 1% dimethyl sulfoxide (DMSO) on alternate days, as a control. Ten mice were euthanized from each group at 30, 60, and 90 days of treatment. Serum levels of luteinizing hormone (LH), follicle-stimulating hormone (FSH), estradiol ($E_2$), and progesterone (P) were assessed. The uterus and ovaries were examined for changes in size or morphology. Results: Serum levels of LH, FSH, $E_2$, and P in the female mice treated with ZEA plus saffron were significantly higher than in those treated with ZEA alone, and were not significantly different from those treated with 1% DMSO. The female mice treated with ZEA alone showed a reduction in size of the uterus and abnormal architecture of the ovaries. Conclusion: The administration of saffron to female mice resulted in a significant reduction in ZEA-induced alterations in reproductive hormone levels, the size of the uterus, and the morphology of the ovaries.
New prospective approaches in controlling the insect infestation in stored grains
Ahmad Mir Shabir,Bashir Mir Mudasir,Ahmad Shah Manzoor,Mumtaz Hamdani Afshan,Valiyapeediyekkal Sunooj Kappat,Phimolsiripol Yuthana,Mousavi Khaneghah Amin 한국응용곤충학회 2023 Journal of Asia-Pacific Entomology Vol.26 No.2
After harvest, food grains are kept in storage facilities for longer periods. Grain infestation during storage causes a significant loss in quality and market value. Various chemical methods have been implemented to control insect infestation in stored grains. However, the chemical fumigants for insects have been limited due to the resistance of insects, environmental concerns, and adverse effects on human health. Therefore, there is a need for viable alternatives for insect disinfestation, which can be residue-free and acceptable at the national and international markets. The new techniques used in the grain industry for insect control during storage gave promising results with high mortality. New methods, such as cold plasma, are becoming a safer tool for the disinfestation of stored grains. The new techniques are rapid and can be applied to bulk material without affecting the quality of grains.
Bashir Ahmad Dar,Meena Sharma,Baldev Singh,Arup Chakraborty,Parduman R. Sharma,Varsha Shrivastava,Amrita Bhowmik,Dushyant Vyas,Prince Bhatti 한국공업화학회 2013 Journal of Industrial and Engineering Chemistry Vol.19 No.3
An easy to prepare aluminium pillared interlayered clay (PILC) has been developed as a stable, recyclable and heterogeneous catalyst to promote the one-pot three component synthesis of a-aminophosphonates under solvent-free conditions using grindstone chemistry. Utilization of mild reaction conditions, clean conversion and greater selectivity under grinding conditions along with effortless separation, and purification of reaction products make this process extra attractive.
Catalyst free, one pot synthesis of phosphoramidates under environment friendly conditions
Bashir Ahmad Dar 한국공업화학회 2016 Journal of Industrial and Engineering Chemistry Vol.36 No.-
An efficient and mild one pot synthesis of phosphoramidates has been reported from simple azideprecursors like benzyl, allyl and propargyl halides. The method is simple, metal free giving products ingood to excellent yields with wide substrate scope. Benzyl halide derivatives (Y–C6H4–CH2–X: X = Cl, Br;Y = p-F, Br, NO2 & o-Cl, NO2) reacted with NaN3 and P(OR’)3 at room temperature gave the correspondingphosphoramidates in 86–96% yields, while the reaction with allyl halides (R1,R2C = CH–CH2–X: X = Cl,Br, R1 & R2 = H, Me) in 60–73% yields. In polar solvents like DMF, DMSO, THF, acetonitrile, methanolmoderate yields were obtained (60%–67%) with incomplete substrate conversion. Yields were better inbinary polar solvents and water–ethanol was found to be the optimum green solvent in which upto 96%yield was obtained within 4.5 h. It was also observed that triethylphosphite showed better reactivitythan trimethylphosphite. Secondary and tertiary halides did not react at all under the optimizedconditions. This is the first catalyst free method for the one pot synthesis of phosphoramidates whichoffers significant green advantages like avoids hazardous organic azides, use of environment friendlyethanol and water as a green reaction medium.
EXISTENCE RESULTS FOR FRACTIONAL DIFFERENTIAL INCLUSIONS WITH SEPARATED BOUNDARY CONDITIONS
Ahmad, Bashir Korean Mathematical Society 2010 대한수학회보 Vol.47 No.4
In this paper, we apply Bohnenblust-Karlins fixed point theorem to prove the existence of solutions for a class of fractional differential inclusions with separated boundary conditions. Some applications of the main result are also presented.